Nonregulated Discovery Bioanalysis

Inotiv provides a fully integrated non-GLP bioanalytical drug discovery solution customized to your company’s project goals. We offer pharmacological and toxicological assessment across multiple therapeutic areas and species to ensure the right studies are performed at the right time.

Our discovery solution supports your therapeutic candidates with in vitro / in vivo DMPK, biology, PK, PD, and toxicology using high-throughput technology platforms. As your partner, you have access to unique insights that rapidly advance your discovery efforts for small molecule and biotherapeutic development.

To talk to an expert about our Nonregulated Bioanalytical Services, please click here.

We offer extensive platform suites available for small molecule bioanalysis, comprised of industry-leading instrumentation to support global studies with rapid, precise, and reproducible results. Discovery bioanalysis platforms include:

Liquid Chromatography, Tandem Mass Spectrometry
- AB SCIEX™ Platform (4000, 5500, 6500, 7500)
Contemporary Method Development
- Ballistic gradients, UPLC-ready columns
Tiered Stage-Appropriate Rigor for Bioanalysis
- Level 1 for screening; Level 2 for non-GLP IND-enabling
High Resolution Mass Spectrometry Technology
- Thermo Exploris™, LTQ Orbitrap, and Agilent 6550 Q-TOF
TECAN – Liquid Handling and Assay Automation
HT Tissue Cryo-Homogenization and VAMS Processing
Watson LIMS™ (Accessioning/PK Analysis) – Discovery Stage

To learn more about our Small Molecule Nonregulated Discovery Bioanalytical service click here.

Our experienced non-GLP bioanalytical team utilize state-of-the-art molecular and cell-based platforms to rapidly develop and validate methods to support the biomarker discovery, gene therapy and biotherapeutic programs. Our capabilities include:

DNA/RNA Isolation
RT-PCR, qPCR
Flow Cytometry
Cytokine Panels
Protein Expression Analysis
ELISA (single and multiplex)
Transporter Assays: Solution Carrier (SLC) and ATP-Binding Cassettes (ABC)
Hepatitis B Virus (HBV) Titers

To learn more about our Biotherapeutic services for Nonregulated Discovery Bioanalytical click here.

Drug Metabolism and Pharmacokinetics (DMPK) Drug Metabolism and Pharmacokinetics (DMPK) Whatever you need, from method development to metabolite ID, our phase-appropriate bioanalytical services help you analyze, answer, and advance.

Histology Histology Our industry-leading histology laboratories support your discovery and nonclinical development projects with a wide range of services. From tissue processing to digital analysis, our team delivers the quality you expect.

Pathology Pathology Access world-class anatomical, clinical, and medical device pathology services, from routine histochemistry, IHC, IF, and ISH to stereology.

In Vivo Services In Vivo Services From discovery to regulatory-enabling safety assessments in advanced developmental and reproductive toxicology (DART), we have the in vivo services and associated bioanalysis capabilities you need to find answers.

Consulting Consulting Our experts deliver the insights you deserve to get the answers you need, whether in DMPK data analysis, biomarker analysis, or bioequivalence studies.

NONREGULATED BIOANALYSIS

Supporting Your Drug Discovery and Nonregulated Bioanalysis