Integrated High-Quality In Vivo Services For Safety Evaluations

Safety pharmacology evaluations are essential in assessing acute risks and potential undesirable effects of novel pharmaceuticals as part of IND-enabling programs.

Use our deep expertise in safety assessment to your advantage. At Inotiv, our team understands the importance and complexity of the drug development process and will be there to guide you to success by offering an integrated safety pharmacology solution that includes respiratory, central nervous system and cardiovascular as a standalone safety pharmacology service or as part of a full IND/CTA program.

Click here to view our presentation: Cardiovascular Safety Pharmacology Best Practice Considerations for the In Vivo QTc Core Assay.

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Gain the insight and expertise to help you progress to your next milestone with:

Fully capable core battery of studies
- Central nervous system (CNS) – functional observational battery of modified Irwin’s
- Telemetered cardiovascular (CV) – blood pressure, heart rate, and electrocardiogram
- Respiratory
  - Plethysmography in rodent
  - Large animal with CV telemetry (large animal cardiopulmonary telemetry)
Regulated or non-regulated services
Expertise in surgical procedures
Integrated safety pharmacology package that includes respiratory, CNS, and CV studies as:
- Standalone services
- Part of a full IND/CTA program
Traditional research models available
Access to industry leading DSI™ hardware and Ponemah software

In Vivo Services In Vivo Services From discovery to regulatory-enabling safety assessments in advanced developmental and reproductive toxicology (DART), we have the in vivo services and associated bioanalysis capabilities you need to find answers.

Surgical Models and Medical Device Testing Surgical Models and Medical Device Testing Our nonclinical testing services feature veterinary surgeons, state-of-the-art imaging, and a commitment to excellence to advance your medical device.

Histology Histology Our industry-leading histology laboratories support your discovery and nonclinical development projects with a wide range of services. From tissue processing to digital analysis, our team delivers the quality you expect.

Pathology Pathology Access world-class anatomical, clinical, and medical device pathology services, from routine histochemistry, IHC, IF, and ISH to stereology.

Consulting Consulting Our experts deliver the insights you deserve to get the answers you need, whether in DMPK data analysis, biomarker analysis, or bioequivalence studies.

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