Typically heterozygous rats are cryo-recovered in 10-12 weeks to an age of 7 weeks old. Subsequently homozygous rats to an age of 7 weeks old can be produced within 20-22 weeks.
Availability: Cryopreserved as heterozygous embryos
Zygosity: Heterozygous as live colony
Developed in collaboration with The Michael J. Fox Foundation, this model contains a deletion of the Lrrk1 gene, encoding for the leucine-rich repeat kinase 1. This model is useful in understanding Lrrk1 biology.