Revitalization

Revitalization is a key component of protecting the future and the integrity of your colony. Inotiv’s extensive experience with revitalization enables us to provide an unparalleled level of personal support in your European* research program. If you need to regenerate a colony of animals from cryopreserved material, Inotiv has a procedure to establish a small cohort of specific pathogen-free animals from cryopreserved material (embryos or sperm). In fact, our experts can discuss with you several revitalization options we offer that are similar to our speed rederivation program.

NOTE: Embryos produced from in vitro fertilization will be transferred into recipient animals to produce the rederived offspring.

*Only available in Europe

Options available:

Service	Requirements	Project outcome
Revitalization of embryos with health screening	100 cryopreserved embryos; Thawing protocol	Revitalization to generate a small cohort (10 offspring) at SOPF Health Status from cryopreserved embryos. Includes rederivation services, recipient and offspring housing and health monitoring.
Revitalization of sperm with health screening (your line can remain at Inotiv for colony maintenance and breeding or shipped back to your facility)	3-5 straws of cryopreserved sperm; Thawing protocol	Revitalization to generate a small cohort (10 offspring) at SOPF Health Status from cryopreserved embryos. Includes rederivation services, recipient and offspring housing and health monitoring.
Revitalization of sperm with health screening (from cryopreserved embryos of a discontinued mouse line)	Minimum of forty (40) cryopreserved embryos	Revitalization to generate a minimum of 1 offspring at SOPF Health Status from cryopreserved embryos of a discontinued line. Includes rederivation services, recipient and offspring housing and health monitoring.