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    Sprague Dawley® outbred rats

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    Aging

    Malmo, V., Kelly, A., Garten, K. S., Stolen, T., Rolim, N. P. L., Wisloff, U., . . . Loennechen, J. P. (2018)., Aerobic interval training prevents age-dependent vulnerability to atrial fibrillation in rodents, Frontiers in Physiology, 9, 206. doi:10.3389/fphys.2018.00206 [doi]
    Pushkar, Y., Robison, G., Sullivan, B., Fu, S. X., Kohne, M., Jiang, W., . . . Zheng, W. (2013)., Aging results in copper accumulations in glial fibrillary acidic protein-positive cells in the subventricular zone., Aging Cell, 12(5), 823-832. doi:10.1111/acel.12112 [doi]
    Cao S, Wastney ME, Lachcik PJ, Xiao HH, Weaver CM, Wong MS., Both Oleanolic Acid and a Mixture of Oleanolic and Ursolic Acids Mimic the Effects of Fructus ligustri lucidi on Bone Properties and Circulating 1,25-Dihydroxycholecalciferol in Ovariectomized Rats, J Nutr. 2018 Dec 1;148(12):1895-1902. doi: 10.1093/jn/nxy242.
    Lukefahr, A. L., Frye, J. B., Wright, L. E., Marion, S. L., Hoyer, P. B., & Funk, J. L. (2012), Decreased bone mineral density in rats rendered follicle-deplete by an ovotoxic chemical correlates with changes in follicle-stimulating hormone and inhibin A., Calcified Tissue International, 90(3), 239-249. doi:10.1007/s00223-011-9565-2 [doi]
    Russ DW, Dimova K, Morris E, Pacheco M, Garvey SM, Scordilis SP., Dietary fish oil supplement induces age-specific contractile and proteomic responses in muscles of male rats, Lipids Health Dis. 2020 Jul 9;19(1):165. doi: 10.1186/s12944-020-01333-4.
    Laast, V. A., Larsen, T., Allison, N., Hoenerhoff, M. J., & Boorman, G. A. (2014), Distinguishing cystic degeneration from other aging lesions in the adrenal cortex of sprague-dawley rats., Toxicologic Pathology, 42(5), 823-829. doi:10.1177/0192623313502258 [doi]
    Thunhorst, R. L., Beltz, T. G., & Johnson, A. K. (2013)., Effects of aging on mineralocorticoid-induced salt appetite in rats, American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 305(12), R1498-505. doi:10.1152/ajpregu.00349.2013 [doi]
    Owusu, B. Y., Stapley, R., Honavar, J., & Patel, R. P. (2013)., Effects of erythrocyte aging on nitric oxide and nitrite metabolism, Antioxidants & Redox Signaling, 19(11), 1198-1208. doi:10.1089/ars.2012.4884 [doi]
    Warden, S. J., Galley, M. R., Hurd, A. L., Wallace, J. M., Gallant, M. A., Richard, J. S., & George, L. A. (2013), Elevated mechanical loading when young provides lifelong benefits to cortical bone properties in female rats independent of a surgically induced menopause., Endocrinology, 154(9), 3178-3187. doi:10.1210/en.2013-1227 [doi]
    Geissler, S., Textor, M., Schmidt-Bleek, K., Klein, O., Thiele, M., Ellinghaus, A., . . . Strube, P. (2013)., In serum veritas-in serum sanitas? cell non-autonomous aging compromises differentiation and survival of mesenchymal stromal cells via the oxidative stress pathway, Cell Death & Disease, 4, e970. doi:10.1038/cddis.2013.501 [doi]
    Witty, C. F., Foster, T. C., Semple-Rowland, S. L., & Daniel, J. M. (2012)., Increasing hippocampal estrogen receptor alpha levels via viral vectors increases MAP kinase activation and enhances memory in aging rats in the absence of ovarian estrogens., PloS One, 7(12), e51385. doi:10.1371/journal.pone.0051385 [doi]
    Stouffer, E. M., & Heisey, J. L. (2013), Latent learning of spatial information is impaired in middle-aged rats., Developmental Psychobiology, 55(3), 309-315. doi:10.1002/dev.21021 [doi]
    Daniel, J. M., Witty, C. F., & Rodgers, S. P. (2015)., Long-term consequences of estrogens administered in midlife on female cognitive aging., Hormones and Behavior, doi:S0018-506X(15)00062-8 [pii]
    Mackert GA, Schulte M, Hirche C, Kotsougiani D, Vogelpohl J, Hoener B, Fiebig T, Kirschner S, Brockmann MA, Lehnhardt M, Kneser U, Harhaus L., Low-energy extracorporeal shockwave therapy (ESWT) improves metaphyseal fracture healing in an osteoporotic rat model, PLoS One. 2017 Dec 12;12(12):e0189356. doi: 10.1371/journal.pone.0189356. eCollection 2017.
    Frye, J. B., Lukefahr, A. L., Wright, L. E., Marion, S. L., Hoyer, P. B., & Funk, J. L. (2012)., Modeling perimenopause in sprague-dawley rats by chemical manipulation of the transition to ovarian failure., Comparative Medicine, 62(3), 193-202.
    Barha, C. K., Lieblich, S. E., Chow, C., & Galea, L. A. (2015)., Multiparity-induced enhancement of hippocampal neurogenesis and spatial memory depends on ovarian hormone status in middle age., Neurobiology of Aging, 36(8), 2391-2405. doi:10.1016/j.neurobiolaging.2015.04.007 [doi]
    Ferreira, J. A., Foley, A. M., & Brown, M. (2012)., Sex hormones differentially influence voluntary running activity, food intake and body weight in aging female and male rats., European Journal of Applied Physiology, 112(8), 3007-3018. doi:10.1007/s00421-011-2271-y [doi]
    Shavlakadze, T., Zhu, J., Wang, S., Zhou, W., Morin, B., Egerman, M. A., . . . Glass, D. J. (2018)., Short-term low-dose mTORC1 inhibition in aged rats counter-regulates age-related gene changes and blocks age-related kidney pathology., The Journals of Gerontology.Series A, Biological Sciences and Medical Sciences, 73(7), 845-852. doi:10.1093/gerona/glx249 [doi]
    Uliana DL, Gomes FV, Grace AA., Stress impacts corticoamygdalar connectivity in an age-dependent manner, Neuropsychopharmacology. 2020 Oct 23. doi: 10.1038/s41386-020-00886-3. Online ahead of print.
    Ho AM, Peyton MP, Scaletty SJ, Trapp S, Schreiber A, Madden BJ, Choi DS, Matthews DB., Chronic Intermittent Ethanol Exposure Alters Behavioral Flexibility in Aged Rats Compared to Adult Rats and Modifies Protein and Protein Pathways Related to Alzheimer's Disease, ACS Omega. 2022 Dec 7;7(50):46260-46276. doi: 10.1021/acsomega.2c04528. eCollection 2022 Dec 20.
    Crowley EK, Grabrucker S, Long-Smith CM, Stack A, O'Gorman DM, Nolan YM., A Reduction in Behavioral Pattern Separation Is Attenuated by Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend in Middle-Aged Rats, J Med Food. 2022 Sep;25(9):924-929. doi: 10.1089/jmf.2020.0213. Epub 2021 Jun 29.
    de Oliveira AA, Mendoza VO, Priviero F, Webb RC, Nunes KP., Age-Related Decline in Vascular Responses to Phenylephrine Is Associated with Reduced Levels of HSP70, Biomolecules. 2022 Aug 16;12(8):1125. doi: 10.3390/biom12081125.
    Yu X, Nguyen P, Burns NC, Heaps CL, Stallone JN, Sohrabji F, Han G., Activation of G protein-coupled estrogen receptor fine-tunes age-related decreased vascular activities in the aortae of female and male rats, Steroids. 2022 Jul;183:108997. doi: 10.1016/j.steroids.2022.108997. Epub 2022 Mar 18.
    Green TRF, Murphy SM, Ortiz JB, Rowe RK., Age-At-Injury Influences the Glial Response to Traumatic Brain Injury in the Cortex of Male Juvenile Rats, Front Neurol. 2022 Jan 17;12:804139. doi: 10.3389/fneur.2021.804139. eCollection 2021.

    Cardiovascular

    Murninkas M, Gillis R, Lee DI, Elyagon S, Bhandarkar NS, Levi O, Polak R, Klapper-Goldstein H, Mulla W, Etzion Y., A new implantable tool for repeated assessment of supraventricular electrophysiology and atrial fibrillation susceptibility in freely moving rats, Am J Physiol Heart Circ Physiol. 2020 Dec 18. doi: 10.1152/ajpheart.00676.2020. Online ahead of print.
    George J, Rappaport M, Shimoni S, Goland S, Voldarsky I, Fabricant Y, Edri O, Cuciuc V, Lifshitz S, Tshori S, Fassler M., A novel monoclonal antibody targeting aggregated transthyretin facilitates its removal and functional recovery in an experimental model, Eur Heart J. 2020 Mar 21;41(12):1260-1270. doi: 10.1093/eurheartj/ehz695.
    Sharifi Kia D, Benza E, Bachman TN, Tushak C, Kim K, Simon MA., Angiotensin Receptor-Neprilysin Inhibition Attenuates Right Ventricular Remodeling in Pulmonary Hypertension, J Am Heart Assoc. 2020 Jul 7;9(13):e015708. doi: 10.1161/JAHA.119.015708. Epub 2020 Jun 18.
    Nural-Guvener, H. F., Mutlu, N., & Gaballa, M. A. (2013)., BACE1 levels are elevated in congestive heart failure, Neuroscience Letters, 532, 7-11. doi:10.1016/j.neulet.2012.10.051 [doi]
    Yu, H., Shao, H., Yan, J., Tsoukias, N. M., & Zhou, M. S. (2012)., Bone marrow transplantation improves endothelial function in hypertensive dahl salt-sensitive rats. Journal, Journal of the American Society of Hypertension : JASH, 6(5), 331-337. doi:10.1016/j.jash.2012.08.003 [doi]
    Stover, K. R., & Cleary, J. D. (2015)., Cardiac response to centrally administered echinocandin antifungals., The Journal of Pharmacy and Pharmacology, 67(9), 1279-1283. doi:10.1111/jphp.12429 [doi]
    Micucci M, Budriesi R, Aldini R, Fato R, Bergamini C, Vivarelli F, Canistro D, Bolchi C, Chiarini A, Rizzardi N, Pallavicini M, Frosini M, Angeletti A., Castanea sativa Mill. bark extract cardiovascular effects in a rat model of high-fat diet, Phytother Res. 2020 Dec 8. doi: 10.1002/ptr.6967. Online ahead of print.
    Wang Z, Cui M, Shah AM, Tan W, Liu N, Bassel-Duby R, Olson EN., Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution, Cell Rep. 2020 Dec 8;33(10):108472. doi: 10.1016/j.celrep.2020.108472.
    Hooper, J. S., Hadley, S. H., Morris, K. F., Breslin, J. W., Dean, J. B., & Taylor-Clark, T. E. (2016)., Characterization of cardiovascular reflexes evoked by airway stimulation with allylisothiocyanate, capsaicin, and ATP in sprague-dawley rats., Journal of Applied Physiology (Bethesda, Md.: 1985), 120(6), 580-591. doi:10.1152/japplphysiol.00944.2015 [doi]
    Hoyt, R. E., Speakman, R. O., Brown, D. R., Cassis, L. A., Silcox, D. L., Anigbogu, C. N., & Randall, D. C. (2013)., Chronic angiotensin-II treatment potentiates HR slowing in sprague-dawley rat during acute behavioral stress. Autonomic Neuroscience, Basic & Clinical, 174(1-2), 42-46. doi:10.1016/j.autneu.2012.12.004 [doi]
    da Silva AA, Pinkerton MA, Spradley FT, Palei AC, Hall JE, do Carmo JM., Chronic CNS-mediated cardiometabolic actions of leptin: potential role of sex differences, Am J Physiol Regul Integr Comp Physiol. 2020 Nov 18. doi: 10.1152/ajpregu.00027.2020. Online ahead of print.
    Wong EM, Tablin F, Schelegle ES., Comparison of nonparametric and parametric methods for time-frequency heart rate variability analysis in a rodent model of cardiovascular disease, PLoS One. 2020 Nov 9;15(11):e0242147. doi: 10.1371/journal.pone.0242147. eCollection 2020.
    Ye, S., Weng, Y., Sun, S., Chen, W., Wu, X., Li, Z., . . . Tang, W. (2012)., Comparison of the durations of mild therapeutic hypothermia on outcome after cardiopulmonary resuscitation in the rat., Circulation, 125(1), 123-129. doi:10.1161/CIRCULATIONAHA.111.062257 [doi]
    Dedkov, E. I., Oak, K., Christensen, L. P., & Tomanek, R. J. (2014)., Coronary vessels and cardiac myocytes of middle-aged rats demonstrate regional sex-specific adaptation in response to postmyocardial infarction remodeling., Biology of Sex Differences, 5(1), 1-6410-5-1. doi:10.1186/2042-6410-5-1 [doi]
    Xia P, Chen J, Liu Y, Fletcher M, Jensen BC, Cheng Z., Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1, J Biol Chem. 2020 Mar 27;295(13):4265-4276. doi: 10.1074/jbc.RA119.011571. Epub 2020 Feb 19.
    Cui M, Wang Z, Chen K, Shah AM, Tan W, Duan L, Sanchez-Ortiz E, Li H, Xu L, Liu N, Bassel-Duby R, Olson EN., Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing, Dev Cell. 2020 Apr 6;53(1):102-116.e8. doi: 10.1016/j.devcel.2020.02.019. Epub 2020 Mar 26.
    Terashvili MN, Kozak KN, Gebremedhin D, Allen LA, Gifford AL, Allen KP, Thulin JD, Lombard JH., Effect of Nearby Construction Activity on Endothelial Function, Sensitivity to Nitric Oxide, and Potassium Channel Activity in the Middle Cerebral Arteries of Rats, J Am Assoc Lab Anim Sci. 2020 May 13;59(4):411-22. doi: 10.30802/AALAS-JAALAS-19-000116. Online ahead of print.
    Gibson, N. M., Quinn, C. J., Pfannenstiel, K. B., Hydock, D. S., & Hayward, R. (2014), Effects of age on multidrug resistance protein expression and doxorubicin accumulation in cardiac and skeletal muscle., Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 44(5), 472-479. doi:10.3109/00498254.2013.846489 [doi]
    Yurista SR, SilljĂŠ HHW, van Goor H, Hillebrands JL, Heerspink HJL, de Menezes Montenegro L, Oberdorf-Maass SU, de Boer RA, Westenbrink BD., Effects of Sodium-Glucose Co-transporter 2 Inhibition with Empaglifozin on Renal Structure and Function in Non-diabetic Rats with Left Ventricular Dysfunction After Myocardial Infarction, Cardiovasc Drugs Ther. 2020 Jun;34(3):311-321. doi: 10.1007/s10557-020-06954-6.
    Bhatia, P. M., Chamberlain, R., Luo, X., Hartley, E. W., & Divani, A. A. (2012)., Elevated blood pressure causes larger hematoma in a rat model of intracerebral hemorrhage, Translational Stroke Research, 3(4), 428-434. doi:10.1007/s12975-012-0199-0 [doi]
    Buniam, Jariya; Chukijrungroat, Natsasi; Khamphaya, Tanaporn; Weerachayaphorn, Jittima; Saengsirisuwan, Vitoon;, Estrogen and voluntary exercise attenuate cardiometabolic syndrome and hepatic steatosis in ovariectomized rats fed a high-fat high-fructose diet. American journal of physiology., Endocrinology and metabolism Vol.316, 2019
    Bradley, J. M., Cryar, K. A., El Hajj, M. C., El Hajj, E. C., & Gardner, J. D. (2013)., Exposure to diesel exhaust particulates induces cardiac dysfunction and remodeling., Journal of Applied Physiology (Bethesda, Md.: 1985), 115(7), 1099-1106. doi:10.1152/japplphysiol.00343.2013 [doi]
    Steagall, R. J., Daniels, C. R., Dalal, S., Joyner, W. L., Singh, M., & Singh, K. (2014)., Extracellular ubiquitin increases expression of angiogenic molecules and stimulates angiogenesis in cardiac microvascular endothelial cells., Microcirculation (New York, N.Y.: 1994), 21(4), 324-332. doi:10.1111/micc.12109 [doi]
    Belanger KM, Crislip GR, Gillis EE, Abdelbary M, Musall JB, Mohamed R, Baban B, Elmarakby A, Brands MW, Sullivan JC., Greater T Regulatory Cells in Females Attenuate DOCA-Salt-Induced Increases in Blood Pressure Versus Males, Hypertension. 2020 Jun;75(6):1615-1623. doi: 10.1161/HYPERTENSIONAHA.119.14089. Epub 2020 Apr 27.
    Garcia-Prieto, C. F., Hernandez-Nuno, F., Rio, D. D., Ruiz-Hurtado, G., Aranguez, I., Ruiz-Gayo, M., . . . Fernandez-Alfonso, M. S. (2015)., High-fat diet induces endothelial dysfunction through a down-regulation of the endothelial AMPK-PI3K-akt-eNOS pathway., Molecular Nutrition & Food Research, 59(3), 520-532. doi:10.1002/mnfr.201400539 [doi]
    Harmon, A., Cornelius, D., Amaral, L., Paige, A., Herse, F., Ibrahim, T., . . . LaMarca, B. (2015)., IL-10 supplementation increases tregs and decreases hypertension in the RUPP rat model of preeclampsia., Hypertension in Pregnancy, 34(3), 291-306. doi:10.3109/10641955.2015.1032054 [doi]
    Carmichael, C. Y., Carmichael, A. C., Kuwabara, J. T., Cunningham, J. T., & Wainford, R. D. (2016), Impaired sodium-evoked paraventricular nucleus neuronal activation and blood pressure regulation in conscious sprague-dawley rats lacking central Galphai2 proteins, Acta Physiologica (Oxford, England), 216(3), 314-329. doi:10.1111/apha.12610 [doi]
    Seymour, A. M., Giles, L., Ball, V., Miller, J. J., Clarke, K., Carr, C. A., & Tyler, D. J. (2015)., In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy, Cardiovascular Research, 106(2), 249-260. doi:10.1093/cvr/cvv101 [doi]
    Ocak U, Eser Ocak P, Huang L, Xu W, Zuo Y, Li P, Gamdzyk M, Zuo G, Mo J, Zhang G, Zhang JH., Inhibition of mast cell tryptase attenuates neuroinflammation via PAR-2/p38/NFÎşB pathway following asphyxial cardiac arrest in rats, J Neuroinflammation. 2020 May 4;17(1):144. doi: 10.1186/s12974-020-01808-2.
    Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD., Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure, Circ Heart Fail. 2020 Dec 28:CIRCHEARTFAILURE120007684. doi: 10.1161/CIRCHEARTFAILURE.120.007684. Online ahead of print.
    Salman IM, Ameer OZ, McMurray S, Giarola AS, Sridhar A, Lewis SJ, Hsieh YH., Laterality Influences Central Integration of Baroreceptor Afferent Input in Male and Female Sprague Dawley Rats, Front Physiol. 2020 May 27;11:499. doi: 10.3389/fphys.2020.00499. eCollection 2020.
    Yang, Y., Wu, Z., Meininger, C. J., & Wu, G. (2015), L-leucine and NO-mediated cardiovascular function., Amino Acids, 47(3), 435-447. doi:10.1007/s00726-014-1904-y [doi]
    Torres Fernandez, E. D., Adams, K. V., Syed, M., Maranon, R. O., Romero, D. G., & Yanes Cardozo, L. L. (2018)., Long-lasting androgen-induced cardiometabolic effects in polycystic ovary syndrome., Journal of the Endocrine Society, 2(8), 949-964. doi:10.1210/js.2018-00131 [doi]
    Patel, J. R., Pleitner, J. M., Moss, R. L., & Greaser, M. L. (2012)., Magnitude of length-dependent changes in contractile properties varies with titin isoform in rat ventricles., American Journal of Physiology.Heart and Circulatory Physiology, 302(3), H697-708. doi:10.1152/ajpheart.00800.2011 [doi]
    Fujioka, H., Tandler, B., & Hoppel, C. L. (2012)., Mitochondrial division in rat cardiomyocytes: An electron microscope study., Anatomical Record (Hoboken, N.J.: 2007), 295(9), 1455-1461. doi:10.1002/ar.22523 [doi]
    Walsh, K. R., Kuwabara, J. T., Shim, J. W., & Wainford, R. D. (2016)., Norepinephrine-evoked salt-sensitive hypertension requires impaired renal sodium chloride cotransporter activity in sprague-dawley rats, American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 310(2), R115-24. doi:10.1152/ajpregu.00514.2014 [doi]
    DiStefano, P. V., Smrcka, A. V., & Glading, A. J. (2016)., Phospholipase cepsilon modulates Rap1 activity and the endothelial barrier. Plo, PloS One, 11(9), e0162338. doi:10.1371/journal.pone.0162338 [doi]
    Manole MD, Hook MJA, Nicholas MA, Nelson BP, Liu AC, Stezoski QC, Rowley AP, Cheng JP, Alexander H, Moschonas EH, Bondi CO, Kline AE., Preclinical neurorehabilitation with environmental enrichment confers cognitive and histological benefits in a model of pediatric asphyxial cardiac arrest, Exp Neurol. 2021 Jan;335:113522. doi: 10.1016/j.expneurol.2020.113522. Epub 2020 Nov 2.
    Cruz, M. V., Luker, J. N., Carney, B. C., Brummel-Ziedins, K. E., Bravo, M. C., Orfeo, T., . . . Shupp, J. W. (2017)., Reference ranges for rotational thromboelastometry in male sprague dawley rats, Thrombosis Journal, 15, 31-017-0154-0. eCollection 2017. doi:10.1186/s12959-017-0154-0 [doi]
    Gliozzi M, Scarano F, Musolino V, Carresi C, Scicchitano M, Ruga S, Zito MC, Nucera S, Bosco F, Maiuolo J, MacrĂŹ R, Guarnieri L, Mollace R, Coppoletta AR, Nicita C, Tavernese A, Palma E, Muscoli C, Mollace V., Role of TSPO/VDAC1 Upregulation and Matrix Metalloproteinase-2 Localization in the Dysfunctional Myocardium of Hyperglycaemic Rats, Int J Mol Sci. 2020 Oct 9;21(20):7432. doi: 10.3390/ijms21207432.
    Sridharan, V., Tripathi, P., Sharma, S., Moros, E. G., Zheng, J., Hauer-Jensen, M., & Boerma, M. (2014)., Roles of sensory nerves in the regulation of radiation-induced structural and functional changes in the heart., International Journal of Radiation Oncology, Biology, Physics, 88(1), 167-174. doi:10.1016/j.ijrobp.2013.10.014 [doi]
    Kochi C, Pokkunuri I, Salvi A, Asghar M, Salim S., Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function, Clin Exp Hypertens. 2020 Aug 17;42(6):571-579. doi: 10.1080/10641963.2020.1766059. Epub 2020 May 19.
    Todorova, V. K., Beggs, M. L., Delongchamp, R. R., Dhakal, I., Makhoul, I., Wei, J. Y., & Klimberg, V. S. (2012)., Transcriptome profiling of peripheral blood cells identifies potential biomarkers for doxorubicin cardiotoxicity in a rat model., PloS One, 7(11), e48398. doi:10.1371/journal.pone.0048398 [doi]
    Buiochi, E. B., Miller, R. J., Hartman, E., Buiochi, F., Bassani, R. A., Costa, E. T., & O'Brien, W. D. (2012)., Transthoracic cardiac ultrasonic stimulation induces a negative chronotropic effect, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 59(12), 2655-2661. doi:10.1109/TUFFC.2012.2506 [doi]
    Nora, G. J., Harun, R., Fine, D. F., Hutchison, D., Grobart, A. C., Stezoski, J. P., . . . Wagner, A. K. (2017)., Ventricular fibrillation cardiac arrest produces a chronic striatal hyperdopaminergic state that is worsened by methylphenidate treatment., Journal of Neurochemistry, 142(2), 305-322. doi:10.1111/jnc.14058 [doi]
    Shafiei-Irannejad V, Abbaszadeh S, Janssen PML, Soraya H., Memantine and its benefits for cancer, cardiovascular and neurological disorders, Eur J Pharmacol. 2021 Nov 5;910:174455. doi: 10.1016/j.ejphar.2021.174455. Epub 2021 Aug 27.
    Yurista SR, Silljé HHW, Nijholt KT, Dokter MM, van Veldhuisen DJ, de Boer RA, Westenbrink BD., Factor Xa Inhibition with Apixaban Does Not Influence Cardiac Remodelling in Rats with Heart Failure After Myocardial Infarction, Cardiovasc Drugs Ther. 2021 Oct;35(5):953-963. doi: 10.1007/s10557-020-06999-7.
    Messmer SJ, Fraser JF, Pennypacker KR, Roberts JM., Method of intra-arterial drug administration in a rat: Sex based optimization of infusion rate, J Neurosci Methods. 2021 Jun 1;357:109178. doi: 10.1016/j.jneumeth.2021.109178. Epub 2021 Apr 2.
    Yu Y, Wei SG, Weiss RM, Felder RB., Silencing Epidermal Growth Factor Receptor in Hypothalamic Paraventricular Nucleus Reduces Extracellular Signal-regulated Kinase 1 and 2 Signaling and Sympathetic Excitation in Heart Failure Rats, Neuroscience. 2021 May 21;463:227-237. doi: 10.1016/j.neuroscience.2021.01.025. Epub 2021 Feb 2.
    Pettinato AM, Yoo D, VanOudenhove J, Chen YS, Cohn R, Ladha FA, Yang X, Thakar K, Romano R, Legere N, Meredith E, Robson P, Regnier M, Cotney JL, Murry CE, Hinson JT., Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment, Cell Rep. 2021 May 4;35(5):109088. doi: 10.1016/j.celrep.2021.109088.
    El-Nachef D, Bugg D, Beussman KM, Steczina S, Martinson AM, Murry CE, Sniadecki NJ, Davis J., Engrafted Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Undergo Clonal Expansion In Vivo, Circulation. 2021 Apr 20;143(16):1635-1638. doi: 10.1161/CIRCULATIONAHA.119.044974. Epub 2021 Apr 19.
    Nguyen ITN, Wiggenhauser LM, Bulthuis M, Hillebrands JL, Feelisch M, Verhaar MC, van Goor H, Joles JA., Cardiac Protection by Oral Sodium Thiosulfate in a Rat Model of L-NNA-Induced Heart Disease, Front Pharmacol. 2021 Apr 15;12:650968. doi: 10.3389/fphar.2021.650968. eCollection 2021.
    Chinyere IR, Hutchinson M, Moukabary T, Koevary JW, Juneman E, Goldman S, Lancaster JJ., Modulating the Infarcted Ventricle's Refractoriness with an Epicardial Biomaterial, J Investig Med. 2021 Feb;69(2):364-370. doi: 10.1136/jim-2020-001486. Epub 2020 Oct 28.
    Chinyere IR, Moukabary T, Hutchinson MD, Lancaster JJ, Juneman E, Goldman S., Progression of infarct-mediated arrhythmogenesis in a rodent model of heart failure, Am J Physiol Heart Circ Physiol. 2021 Jan 1;320(1):H108-H116. doi: 10.1152/ajpheart.00639.2020. Epub 2020 Nov 8.
    Manole MD, Hook MJA, Nicholas MA, Nelson BP, Liu AC, Stezoski QC, Rowley AP, Cheng JP, Alexander H, Moschonas EH, Bondi CO, Kline AE., Preclinical neurorehabilitation with environmental enrichment confers cognitive and histological benefits in a model of pediatric asphyxial cardiac arrest, Exp Neurol. 2021 Jan;335:113522. doi: 10.1016/j.expneurol.2020.113522. Epub 2020 Nov 2.
    Almutlaq RN, Newell-Fugate AE, Evans LC, Fatima H, Gohar EY., Aromatase inhibition increases blood pressure and markers of renal injury in female rats, Am J Physiol Renal Physiol. 2022 Sep 1;323(3):F349-F360. doi: 10.1152/ajprenal.00055.2022. Epub 2022 Jul 28.
    Das S, Komnenov D, Newhouse L, Rishi AK, Rossi NF., Paraventricular Nucleus V(1a) Receptor Knockdown Blunts Neurocardiovascular Responses to Acute Stress in Male Rats after Chronic Mild Unpredictable Stress, Physiol Behav. 2022 Sep 1;253:113867. doi: 10.1016/j.physbeh.2022.113867. Epub 2022 Jun 2.
    Getsy PM, Young AP, Grossfield A, Seckler JM, Wilson CG, Gaston B, Bates JN, Lewis SJ., D-cysteine ethyl ester and D-cystine dimethyl ester reverse the deleterious effects of morphine on arterial blood-gas chemistry and Alveolar-arterial gradient in anesthetized rats, Respir Physiol Neurobiol. 2022 Aug;302:103912. doi: 10.1016/j.resp.2022.103912. Epub 2022 Apr 18.
    He F, Zheng G, Hu J, Ge W, Ji X, Bradley JL, Peberdy MA, Ornato JP, Tang W., Necrosulfonamide improves post-resuscitation myocardial dysfunction via inhibiting pyroptosis and necroptosis in a rat model of cardiac arrest, Eur J Pharmacol. 2022 Jul 5;926:175037. doi: 10.1016/j.ejphar.2022.175037. Epub 2022 May 16.
    Cho JS, Han YS, Jensen C, Sieck G., Effects of arginase inhibition on myocardial Ca(2+) and contractile responses, Physiol Rep. 2022 Jul;10(14):e15396. doi: 10.14814/phy2.15396.
    Morin EE, Salbato S, Walker BR, Naik JS., Endothelial cell membrane cholesterol content regulates the contribution of TRPV4 channels in ACh-induced vasodilation in rat gracilis arteries, Microcirculation. 2022 Jul;29(4-5):e12774. doi: 10.1111/micc.12774. Epub 2022 Jun 21.
    Mohamed R, Crislip GR, McLarnon S, Wei Q, O'Connor PM, Sullivan JC., Persistent vascular congestion in male spontaneously hypertensive rats contributes to delayed recovery of renal function following renal ischemia perfusion compared with females, Clin Sci (Lond). 2022 Jun 17;136(11):825-840. doi: 10.1042/CS20220002.
    Rahimi O, Melo AC, Westwood B, Grier RDM, Tallant EA, Gallagher PE., Angiotensin-(1-7) reduces doxorubicin-induced aortic arch dysfunction in male and female juvenile Sprague Dawley rats through pleiotropic mechanisms, Peptides. 2022 Jun;152:170784. doi: 10.1016/j.peptides.2022.170784. Epub 2022 Mar 12.
    Ledford BT, Akerman AW, Sun K, Gillis DC, Weiss JM, Vang J, Willcox S, Clemons TD, Sai H, Qiu R, Karver MR, Griffith JD, Tsihlis ND, Stupp SI, Ikonomidis JS, Kibbe MR., Peptide Amphiphile Supramolecular Nanofibers Designed to Target Abdominal Aortic Aneurysms, ACS Nano. 2022 May 24;16(5):7309-7322. doi: 10.1021/acsnano.1c06258. Epub 2022 May 3.
    Alexander ED, Aldridge JL, Burleson TS, Frasier CR., Teriflunomide treatment exacerbates cardiac ischemia reperfusion injury in isolated rat hearts, Cardiovasc Drugs Ther. 2022 Apr 30:1-6. doi: 10.1007/s10557-022-07341-z. Online ahead of print.
    Gohar EY, De Miguel C, Obi IE, Daugherty EM, Hyndman KA, Becker BK, Jin C, Sedaka R, Johnston JG, Liu P, Speed JS, Mitchell T, Kriegel AJ, Pollock JS, Pollock DM., Acclimation to a High-Salt Diet Is Sex Dependent, J Am Heart Assoc. 2022 Mar;11(5):e020450. doi: 10.1161/JAHA.120.020450. Epub 2022 Feb 22.
    Cramer M, Chang J, Li H, Serrero A, El-Kurdi M, Cox M, Schoen FJ, Badylak SF., Tissue response, macrophage phenotype, and intrinsic calcification induced by cardiovascular biomaterials: Can clinical regenerative potential be predicted in a rat subcutaneous implant model?, J Biomed Mater Res A. 2022 Feb;110(2):245-256. doi: 10.1002/jbm.a.37280. Epub 2021 Jul 29.
    Frame AA, Nist KM, Kim K, Kuwabara JT, Wainford RD., Natriuresis During an Acute Intravenous Sodium Chloride Infusion in Conscious Sprague Dawley Rats Is Mediated by a Blood Pressure-Independent α(1)-Adrenoceptor-Mediated Mechanism, Front Physiol. 2022 Jan 17;12:784957. doi: 10.3389/fphys.2021.784957. eCollection 2021.

    COVID-19

    Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R., SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia, Pain. 2020 Oct 1. doi: 10.1097/j.pain.0000000000002097. Online ahead of print.

    Diabetes induced obesity

    Aranaz P , Zabala M , Romo-Hualde A , Navarro-Herrera D , LĂłpez-Yoldi M , Vizmanos JL , MartĂ­nez JA , Milagro FI , GonzĂĄlez-Navarro CJ ., A combination of borage seed oil and quercetin reduces fat accumulation and improves insulin sensitivity in obese rats, Food Funct. 2020 May 1;11(5):4512-4524. doi: 10.1039/d0fo00504e. Epub 2020 May 11.
    Daniels SJ, Leeming DJ, Detlefsen S, Bruun MF, Hjuler ST, Henriksen K, Hein P, Krag A, Karsdal MA, Nielsen MJ, Brockbank S, Cruwys S., Addition of trans fat and alcohol has divergent effects on atherogenic diet-induced liver injury in rodent models of steatohepatitis, Am J Physiol Gastrointest Liver Physiol. 2020 Mar 1;318(3):G410-G418. doi: 10.1152/ajpgi.00066.2019. Epub 2020 Jan 6.
    Derman RC, Ferrario CR., Affective Pavlovian motivation is enhanced in obesity susceptible populations: Implications for incentive motivation in obesity, Behav Brain Res. 2020 Feb 17;380:112318. doi: 10.1016/j.bbr.2019.112318. Epub 2019 Nov 21.
    Ansari P, Flatt PR, Harriott P, Abdel-Wahab YHA., Anti-hyperglycaemic and insulin releasing effects of Camellia sinensis leaves and isolation and characterization of active compounds, Br J Nutr. 2020 Dec 17:1-35. doi: 10.1017/S0007114520005085. Online ahead of print.
    Noli B, Brancia C, Corda G, Ferri GL, Cocco C., Dynamic of TLQP-peptides upon fasting, Tissue Cell. 2020 Aug;65:101368. doi: 10.1016/j.tice.2020.101368. Epub 2020 Apr 15.
    Ansari P, Hannon-Fletcher MP, Flatt P, Abdel-Wahab YHA., Effects of 22 traditional anti-diabetic medicinal plants on DPP-IV enzyme activity and glucose homeostasis in high-fat fed obese diabetic rats, Biosci Rep. 2021 Jan 8:BSR20203824. doi: 10.1042/BSR20203824. Online ahead of print.
    Ansari P, Flatt PR, Harriott P, Abdel-Wahab YHA., Evaluation of the Antidiabetic and Insulin Releasing Effects of A. squamosa, Including Isolation and Characterization of Active Phytochemicals, Plants (Basel). 2020 Oct 12;9(10):1348. doi: 10.3390/plants9101348.
    Richardson JR, O'Dell LE, Nazarian A., Examination of nicotine and saccharin reward in the Goto-Kakizaki diabetic rat model, Neurosci Lett. 2020 Mar 16;721:134825. doi: 10.1016/j.neulet.2020.134825. Epub 2020 Feb 6.
    Volcko KL, Carroll QE, Brakey DJ, Daniels D., High-fat diet alters fluid intake without reducing sensitivity to glucagon-like peptide-1 receptor agonist effects, Physiol Behav. 2020 Jul 1;221:112910. doi: 10.1016/j.physbeh.2020.112910. Epub 2020 Apr 10.
    Han L, Bittner S, Dong D, Cortez Y, Bittner A, Chan J, Umar M, Shen WJ, Peterson RG, Kraemer FB, Azhar S., Molecular changes in hepatic metabolism in ZDSD rats-A new polygenic rodent model of obesity, metabolic syndrome, and diabetes, Biochim Biophys Acta Mol Basis Dis. 2020 May 1;1866(5):165688. doi: 10.1016/j.bbadis.2020.165688. Epub 2020 Jan 24.
    Yang TY, Gardner JC, Gao Z, Pan YX, Liang NC., Role of glucocorticoid signaling in exercise-associated changes in high-fat diet preference in rats, Am J Physiol Regul Integr Comp Physiol. 2020 Mar 1;318(3):R515-R528. doi: 10.1152/ajpregu.00288.2019. Epub 2020 Jan 15.
    Yang TY, Gao Z, Liang NC., Sex-Dependent Wheel Running Effects on High Fat Diet Preference, Metabolic Outcomes, and Performance on the Barnes Maze in Rats, Nutrients. 2020 Sep 5;12(9):2721. doi: 10.3390/nu12092721.
    Larsen AT, Gydesen S, Sonne N, Karsdal MA, Henriksen K., The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile, BMC Endocr Disord. 2021 Jan 7;21(1):10. doi: 10.1186/s12902-020-00678-2.
    Sonne N, Larsen AT, Andreassen KV, Karsdal MA, Henriksen K., The Dual Amylin and Calcitonin Receptor Agonist, KBP-066, Induces an Equally Potent Weight Loss Across a Broad Dose Range While Higher Doses May Further Improve Insulin Action, J Pharmacol Exp Ther. 2020 Apr;373(1):92-102. doi: 10.1124/jpet.119.263723. Epub 2020 Jan 28.
    Saande CJ, Bries AE, Pritchard SK, Nass CA, Reed CH, Rowling MJ, Schalinske KL., Whole Egg Consumption Decreases Cumulative Weight Gain in Diet-Induced Obese Rats, J Nutr. 2020 Jul 1;150(7):1818-1823. doi: 10.1093/jn/nxaa114.
    Niepoetter P, Butts-Wilmsmeyer C, Kaviani S, Viernow C, Ruholl H, Gopalan C., Correlation between ketones and mental fatigue in high fat-induced obese and non-obese rats, Physiol Rep. 2021 Jul;9(13):e14930. doi: 10.14814/phy2.14930.
    Dasilva G, Lois S, Méndez L, Miralles-Pérez B, Romeu M, Ramos-Romero S, Torres JL, Medina I., Fish Oil Improves Pathway-Oriented Profiling of Lipid Mediators for Maintaining Metabolic Homeostasis in Adipose Tissue of Prediabetic Rats, Front Immunol. 2021 Apr 21;12:608875. doi: 10.3389/fimmu.2021.608875. eCollection 2021.
    Roglans N, Fauste E, Bentanachs R, Velázquez AM, Pérez-Armas M, Donis C, Panadero MI, Alegret M, Otero P, Bocos C, Laguna JC., Bempedoic Acid Restores Liver H(2)S Production in a Female Sprague-Dawley Rat Dietary Model of Non-Alcoholic Fatty Liver, Int J Mol Sci. 2022 Dec 28;24(1):473. doi: 10.3390/ijms24010473.
    Jobgen WS, Lee MJ, Fried SK, Wu G., l-Arginine supplementation regulates energy-substrate metabolism in skeletal muscle and adipose tissue of diet-induced obese rats, Exp Biol Med (Maywood). 2022 Dec 21:15353702221139207. doi: 10.1177/15353702221139207. Online ahead of print.
    Niepoetter P, Butts-Wilmsmeyer C, Gopalan C., Intermittent fasting and mental and physical fatigue in obese and non-obese rats, PLoS One. 2022 Nov 2;17(11):e0275684. doi: 10.1371/journal.pone.0275684. eCollection 2022.
    Sonne N, Larsen AT, Karsdal MA, Henriksen K., The Impact of Exposure Profile on the Efficacy of Dual Amylin and Calcitonin Receptor Agonist Therapy, Biomedicines. 2022 Sep 22;10(10):2365. doi: 10.3390/biomedicines10102365.
    Kamat V, Radtke JR, Hu Q, Wang W, Sweet IR, Hampe CS., Autoantibodies directed against glutamate decarboxylase interfere with glucose-stimulated insulin secretion in dispersed rat islets, Int J Exp Pathol. 2022 Aug;103(4):140-148. doi: 10.1111/iep.12437. Epub 2022 Mar 4.
    Pathak R, Kumar A, Palfrey HA, Stone KP, Raju NR, Gettys TW, Murthy SN., Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague-Dawley rats fed a high-cholesterol diet, Inflamm Res. 2022 Jun;71(5-6):711-722. doi: 10.1007/s00011-022-01572-4. Epub 2022 May 16.
    Yun H, Dumbell R, Hanna K, Bowen J, McLean SL, Kantamneni S, Pors K, Wu QF, Helfer G., The Chemerin-CMKLR1 Axis is Functionally important for Central Regulation of Energy Homeostasis, Front Physiol. 2022 May 30;13:897105. doi: 10.3389/fphys.2022.897105. eCollection 2022.
    Bier A, Shapira E, Khasbab R, Sharabi Y, Grossman E, Leibowitz A., High-Fructose Diet Increases Renal ChREBPβ Expression, Leading to Intrarenal Fat Accumulation in a Rat Model with Metabolic Syndrome, Biology (Basel). 2022 Apr 18;11(4):618. doi: 10.3390/biology11040618.

    Diet induced obesity

    Hsu, T. M., Noble, E. E., Liu, C. M., Cortella, A. M., Konanur, V. R., Suarez, A. N., . . . Kanoski, S. E. (2018), A hippocampus to prefrontal cortex neural pathway inhibits food motivation through glucagon-like peptide-1 signaling, Molecular Psychiatry, 23(7), 1555-1565. doi:10.1038/mp.2017.91 [doi]
    Davidson, E. P., Coppey, L. J., Kardon, R. H., & Yorek, M. A. (2014)., Differences and similarities in development of corneal nerve damage and peripheral neuropathy and in diet-induced obesity and type 2 diabetic rats., Investigative Ophthalmology & Visual Science, 55(3), 1222-1230. doi:10.1167/iovs.13-13794 [doi]
    Apolzan, J. W., & Harris, R. B. (2012)., Differential effects of chow and purified diet on the consumption of sucrose solution and lard and the development of obesity., Physiology & Behavior, 105(2), 325-331. doi:10.1016/j.physbeh.2011.08.023 [doi]
    Wu, M. J., & Chang, C. J. (2016), High fat diet-induced breast cancer model in rat., Bio-Protocol, 6(13), 10.21769/BioProtoc.1852. doi:e1852 [pii]
    Song, M., Schuschke, D. A., Zhou, Z., Chen, T., Pierce, W. M.,Jr, Wang, R., . . . McClain, C. J. (2012), High fructose feeding induces copper deficiency in sprague-dawley rats: A novel mechanism for obesity related fatty liver, Journal of Hepatology, 56(2), 433-440. doi:10.1016/j.jhep.2011.05.030 [doi]
    Song, Z., Xie, W., Chen, S., Strong, J. A., Print, M. S., Wang, J. I., . . . Zhang, J. M. (2017)., High-fat diet increases pain behaviors in rats with or without obesity., Scientific Reports, 7(1), 10350-017-10458-z. doi:10.1038/s41598-017-10458-z [doi]
    Stengel, A., Goebel-Stengel, M., Wang, L., Hu, E., Karasawa, H., Pisegna, J. R., & Tache, Y. (2013)., High-protein diet selectively reduces fat mass and improves glucose tolerance in western-type diet-induced obese rats., American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 305(6), R582-91. doi:10.1152/ajpregu.00598.2012 [doi]
    Liu, Xuefei; Zheng, Hong;, Leptin-Mediated Sympathoexcitation in Obese Rats: Role for Neuron-Astrocyte Crosstalk in the Arcuate Nucleus., Frontiers in neuroscience Vol.13, 2019
    Lee, S. J., Sanchez-Watts, G., Krieger, J. P., Pignalosa, A., Norell, P. N., Cortella, A., . . . Watts, A. G. (2018), Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity., Molecular Metabolism, 11, 33-46. doi:S2212-8778(18)30143-1 [pii]
    Vivarelli, F., Canistro, D., Sapone, A., De Nicola, G. R., Babot Marquillas, C., Iori, R., . . . Paolini, M. (2016)., Raphanus sativus cv. sango sprout juice decreases diet-induced obesity in sprague dawley rats and ameliorates related disorders., PloS One, 11(3), e0150913. doi:10.1371/journal.pone.0150913 [doi]
    Northcott, C. A., Fink, G. D., Garver, H., Haywood, J. R., Laimon-Thomson, E. L., McClain, J. L., . . . Dorrance, A. M. (2012)., The development of hypertension and hyperaldosteronism in a rodent model of life-long obesity, Endocrinology, 153(4), 1764-1773. doi:10.1210/en.2011-1176 [doi]
    Davidson, T. L., Monnot, A., Neal, A. U., Martin, A. A., Horton, J. J., & Zheng, W. (2012), The effects of a high-energy diet on hippocampal-dependent discrimination performance and blood-brain barrier integrity differ for diet-induced obese and diet-resistant rats, Physiology & Behavior, 107(1), 26-33. doi:10.1016/j.physbeh.2012.05.015 [doi]

    General studies

    Taki, F. A., Abdel-Rahman, A. A., & Zhang, B. (2014)., A comprehensive approach to identify reliable reference gene candidates to investigate the link between alcoholism and endocrinology in sprague-dawley rats, PloS One, 9(5), e94311. doi:10.1371/journal.pone.0094311 [doi]
    Stouffer, E. M., Warninger, E. E., & Michener, P. N. (2015)., A high-fat diet impairs learning that is dependent on the dorsal hippocampus but spares other forms of learning., Hippocampus, doi:10.1002/hipo.22476 [doi]
    Edwards J, Kowal M, VanDreel A, Lamar P, Prozialeck W., A Method for the Evaluation of Site-Specific Nephrotoxic Injury in the Intact Rat Kidney, Toxics. 2020 Jan 20;8(1):4. doi: 10.3390/toxics8010004.
    Carvajal Monroy, P. L., Grefte, S., Kuijpers-Jagtman, A. M., Helmich, M. P., Ulrich, D. J., Von den Hoff, J. W., & Wagener, F. A. (2013), A rat model for muscle regeneration in the soft palate, PloS One, 8(3), e59193. doi:10.1371/journal.pone.0059193 [doi]
    Sharma PK, Avula B, Panda A, Wang YH, Khan IA, Murthy SN., A sensitive bioanalytical method for quantitative determination of resiniferatoxin in rat plasma using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and its application in pharmacokinetic study, J Pharm Biomed Anal. 2019 Feb 20;165:284-291. doi: 10.1016/j.jpba.2018.12.024. Epub 2018 Dec 14.
    Hurley MM, Anderson EM, Chen C, Maunze B, Hess EM, Block ME, Patel N, Cooper Z, McCoy R, Dabra T, Conley W, Reilly MJ, Hearing M, Choi S., Acute Blockade of PACAP-Dependent Activity in the Ventromedial Nucleus of the Hypothalamus Disrupts Leptin-Induced Behavioral and Molecular Changes in Rats, Neuroendocrinology. 2020;110(3-4):271-281. doi: 10.1159/000501337. Epub 2019 Jun 6.
    Lovelock DF, Deak T., Acute stress imposed during adolescence has minimal effects on hypothalamic-pituitary-adrenal (HPA) axis sensitivity in adulthood in female Sprague Dawley rats, Physiol Behav. 2020 Jan 1;213:112707. doi: 10.1016/j.physbeh.2019.112707. Epub 2019 Oct 18.
    Przybysz, K. R., Werner, D. F., & Diaz, M. R. (2017), Age-dependent regulation of GABA transmission by kappa opioid receptors in the basolateral amygdala of sprague-dawley rats., Neuropharmacology, 117, 124-133. doi:S0028-3908(17)30035-7 [pii]
    King, H. E., Wetzell, B., Rice, K. C., & Riley, A. L. (2015), An assessment of MDPV-induced place preference in adult sprague-dawley rats., Drug and Alcohol Dependence, 146, 116-119. doi:10.1016/j.drugalcdep.2014.11.002 [doi]
    Radford KD, Spencer HF, Zhang M, Berman RY, Girasek QL, Choi KH., Association between intravenous ketamine-induced stress hormone levels and long-term fear memory renewal in Sprague-Dawley rats, Behav Brain Res. 2020 Jan 27;378:112259. doi: 10.1016/j.bbr.2019.112259. Epub 2019 Sep 24.
    Kramer, P. R., Umorin, M., & Bellinger, L. L. (2015)., Attenuation of myogenic orofacial nociception and mechanical hypersensitivity by viral mediated enkephalin overproduction in male and female rats., BMC Neurology, 15, 34-015-0285-5. doi:10.1186/s12883-015-0285-5 [doi]
    Gatch MB, Shetty RA, Sumien N, Forster MJ., Behavioral effects of four novel synthetic cathinone analogs in rodents, Addict Biol. 2020 Nov 5:e12987. doi: 10.1111/adb.12987. Online ahead of print.
    Jackson, K. L., Dayton, R. D., Deverman, B. E., & Klein, R. L. (2016)., Better targeting, better efficiency for wide-scale neuronal transduction with the synapsin promoter and AAV-PHP.B., Frontiers in Molecular Neuroscience, 9, 116. doi:10.3389/fnmol.2016.00116 [doi]
    Podoll, Terry; Pearson, Paul G; Evarts, Jerry; Ingallinera, Tim; Bibikova, Elena; Sun, Hao; Gohdes, Mark; Cardinal, Kristen; Sanghvi, Mitesh; Slatter, J Greg;, Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Human, Drug metabolism and disposition: the biological fate of chemicals Vol.47, 2019
    Gupta, A., Liberati, T. A., Verhulst, S. J., Main, B. J., Roberts, M. H., Potty, A. G., . . . El-Amin Iii, S. F. (2015), Biocompatibility of single-walled carbon nanotube composites for bone regeneration, Bone & Joint Research, 4(5), 70-77. doi:10.1302/2046-3758.45.2000382 [doi]
    Calik, M. W., & Carley, D. W. (2014), Cannabinoid type 1 and type 2 receptor antagonists prevent attenuation of serotonin-induced reflex apneas by dronabinol in sprague-dawley rats, PloS One, 9(10), e111412. doi:10.1371/journal.pone.0111412 [doi]
    Revollo JR, Dad A, Pearce MG, Mittelstaedt RA, Casildo A, Lapidus RG, Robison TW, Dobrovolsky VN., CD59-deficient bone marrow erythroid cells from rats treated with procarbazine and propyl-nitrosourea have mutations in the Pig-a gene, Environ Mol Mutagen. 2020 Oct;61(8):797-806. doi: 10.1002/em.22402. Epub 2020 Aug 18.
    Schalla MA, Kühne SG, Friedrich T, Kobelt P, Goebel-Stengel M, Long M, Rivalan M, Winter Y, Mori M, Rose M, Stengel A., Central blockage of nesfatin-1 has anxiolytic effects but does not prevent corticotropin-releasing factor-induced anxiety in male rats, Biochem Biophys Res Commun. 2020 Aug 27;529(3):773-777. doi: 10.1016/j.bbrc.2020.05.163. Epub 2020 Jul 19.
    Liu CM, Hsu TM, Suarez AN, Subramanian KS, Fatemi RA, Cortella AM, Noble EE, Roitman MF, Kanoski SE., Central oxytocin signaling inhibits food reward-motivated behaviors and VTA dopamine responses to food-predictive cues in male rats, Horm Behav. 2020 Nov;126:104855. doi: 10.1016/j.yhbeh.2020.104855. Epub 2020 Oct 1.
    Zimmerman, M. A., Baban, B., Tipton, A. J., O'Connor, P. M., & Sullivan, J. C. (2015)., Chronic ANG II infusion induces sex-specific increases in renal T cells in sprague-dawley rats., American Journal of Physiology.Renal Physiology, 308(7), F706-12. doi:10.1152/ajprenal.00446.2014 [doi]
    Van Skike, C. E., Diaz-Granados, J. L., & Matthews, D. B. (2015)., Chronic intermittent ethanol exposure produces persistent anxiety in adolescent and adult rats., Alcoholism, Clinical and Experimental Research, 39(2), 262-271. doi:10.1111/acer.12617 [doi]
    Shao XM, Liu S, Lee ES, Fung D, Pei H, Liang J, Mudgway R, Zhang J, Feldman JL, Zhu Y, Louie S, Xie XS., Chronic intermittent nicotine delivery via lung alveolar region-targeted aerosol technology produces circadian pharmacokinetics in rats resembling human smokers, J Appl Physiol (1985). 2018 Nov 1;125(5):1555-1562. doi: 10.1152/japplphysiol.00357.2018. Epub 2018 Sep 20.
    Vaziri, N. D., Yuan, J., Nazertehrani, S., Ni, Z., & Liu, S. (2013), Chronic kidney disease causes disruption of gastric and small intestinal epithelial tight junction., American Journal of Nephrology, 38(2), 99-103. doi:10.1159/000353764 [doi]
    Masyuk, A. I., Huang, B. Q., Radtke, B. N., Gajdos, G. B., Splinter, P. L., Masyuk, T. V., . . . LaRusso, N. F. (2013)., Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling, American Journal of Physiology.Gastrointestinal and Liver Physiology, 304(11), G1013-24. doi:10.1152/ajpgi.00383.2012 [doi]
    Jin, Y., Peng, Y., Lin, Z., Chen, Y. C., Wei, L., Hacker, T. A., . . . Ge, Y. (2016)., Comprehensive analysis of tropomyosin isoforms in skeletal muscles by top-down proteomics, Journal of Muscle Research and Cell Motility, 37(1-2), 41-52. doi:10.1007/s10974-016-9443-7 [doi]
    Zanca, Roseanna M; Sanay, Shirley; Avila, Jorge A; Rodriguez, Edgar; Shair, Harry N; Serrano, Peter A;, Contextual fear memory modulates PSD95 phosphorylation, AMPAr subunits, PKMÎś and PI3K differentially between adult and juvenile rats., Neurobiology of stress Vol.10, 2019
    Northcutt, A. L., Hutchinson, M. R., Wang, X., Baratta, M. V., Hiranita, T., Cochran, T. A., . . . Watkins, L. R. (2015)., DAT isn't all that: Cocaine reward and reinforcement require toll-like receptor 4 signaling, Molecular Psychiatry, doi:10.1038/mp.2014.177 [doi]
    Palmieri J, Spiegler KM, Pang KCH, Myers CE., Dataset of active avoidance in Wistar-Kyoto and Sprague Dawley rats: Experimental data and reinforcement learning model code and output, Data Brief. 2020 Jul 25;32:106074. doi: 10.1016/j.dib.2020.106074. eCollection 2020 Oct.
    Feng, X., Zhang, T., Ralston, E., & Ludlow, C. L. (2012), Differences in neuromuscular junctions of laryngeal and limb muscles in rats, The Laryngoscope, 122(5), 1093-1098. doi:10.1002/lary.23218 [doi]
    Netser S, Meyer A, Magalnik H, Zylbertal A, de la Zerda SH, Briller M, Bizer A, Grinevich V, Wagner S., Distinct dynamics of social motivation drive differential social behavior in laboratory rat and mouse strains, Nat Commun. 2020 Nov 20;11(1):5908. doi: 10.1038/s41467-020-19569-0.
    GĂśk C, Plain F, Robertson AD, Howie J, Baillie GS, Fraser NJ, Fuller W., Dynamic Palmitoylation of the Sodium-Calcium Exchanger Modulates Its Structure, Affinity for Lipid-Ordered Domains, and Inhibition by XIP, Cell Rep. 2020 Jun 9;31(10):107697. doi: 10.1016/j.celrep.2020.107697.
    McFadden T, Musaus M, Nelsen JL, Martin K, Jones N, Smith P, Kugler H, Jarome TJ., Dysregulation of protein degradation in the hippocampus is associated with impaired spatial memory during the development of obesity, Behav Brain Res. 2020 Sep 1;393:112787. doi: 10.1016/j.bbr.2020.112787. Epub 2020 Jun 27.
    Diana P, Joksimovic SM, Faisant A, Jevtovic-Todorovic V., Early exposure to general anesthesia impairs social and emotional development in rats, Mol Neurobiol. 2020 Jan;57(1):41-50. doi: 10.1007/s12035-019-01755-x. Epub 2019 Sep 7.
    Koontz, J. M., Kumsher, D. M., Kelly, R.,3rd, & Stallings, J. D. (2016)., Effect of 2 bedding materials on ammonia levels in individually ventilated cages, Journal of the American Association for Laboratory Animal Science : JAALAS, 55(1), 25-28.
    Pan, L., Gelzleichter, T., Chen, Y., Burg, C., Limb, S. L., & Nguyen, L. (2018)., Effect of pirfenidone on gastric emptying in a rat model, Pulmonary Pharmacology & Therapeutics, 51, 41-47. doi:S1094-5539(18)30019-1 [pii]
    Delaplain, Patrick T; Bell, Brandon A; Wang, Jin; Isani, Mubina; Zhang, Emily; Gayer, Christopher P; Grishin, Anatoly V; Ford, Henri R;, Effects of artificially introduced Enterococcus faecalis strains in experimental necrotizing enterocolitis., PloS one Vol.14, 2019
    More, A. S., Mishra, J. S., Hankins, G. D., Yallampalli, C., & Sathishkumar, K. (2015)., Enalapril normalizes endothelium-derived hyperpolarizing factor-mediated relaxation in mesenteric artery of adult hypertensive rats prenatally exposed to testosterone, Biology of Reproduction, 92(6), 155. doi:10.1095/biolreprod.115.130468 [doi]
    Parrish, Jenna N; Bertholomey, Megan L; Pang, Hong W; Speth, Robert C; Torregrossa, Mary M;, Estradiol modulation of the renin-angiotensin system and the regulation of fear extinction., Translational psychiatry Vol.9, 2019
    Wu, Heng; Ploeger, Jonathan M; Kamarajugadda, Sushama; Mashek, Douglas G; Mashek, Mara T; Manivel, Juan C; Shekels, Laurie L; Lapiro, Jessica L; Albrecht, Jeffrey H;, Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes., Hepatology communications Vol.3, 2019
    Posillico, C. K., Terasaki, L. S., Bilbo, S. D., & Schwarz, J. M. (2015)., Examination of sex and minocycline treatment on acute morphine-induced analgesia and inflammatory gene expression along the pain pathway in sprague-dawley rats, Biology of Sex Differences, 6, 33-015-0049-3. eCollection 2015. doi:10.1186/s13293-015-0049-3 [doi]
    Pilatz, A., Ceylan, I., Schuppe, H. C., Ludwig, M., Fijak, M., Chakraborty, T., . . . Wagenlehner, F. (2015)., Experimental escherichia coli epididymitis in rats: Assessment of testicular involvement in a long-term follow-up., Andrologia, 47(2), 160-167. doi:10.1111/and.12239 [doi]
    Wilson, C. A., Vazdarjanova, A., & Terry, A. V.,Jr. (2013), Exposure to variable prenatal stress in rats: Effects on anxiety-related behaviors, innate and contextual fear, and fear extinction., Behavioural Brain Research, 238, 279-288. doi:10.1016/j.bbr.2012.10.003 [doi]
    Soliman RH, Johnston JG, Gohar EY, Taylor CM, Pollock DM., Greater natriuretic response to ENaC inhibition in male versus female Sprague-Dawley rats, Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R418-R427. doi: 10.1152/ajpregu.00060.2019. Epub 2020 Jan 8.
    Luo, Liqing; Martin, Sherry C; Parkington, Jascha; Cadena, Samuel M; Zhu, Jiang; Ibebunjo, Chikwendu; Summermatter, Serge; Londraville, Nicole; Patora-Komisarska, Krystyna; Widler, Leo; Zhai, Huili; Trendelenburg, Anne-Ulrike; Glass, David J; Shi, Jun, HDAC4 Controls Muscle Homeostasis through Deacetylation of Myosin Heavy Chain, PGC-1Îą, and Hsc70., Cell reports Vol.29, 2019
    Pitchers, K. K., Kane, L. F., Kim, Y., Robinson, T. E., & Sarter, M. (2017)., 'Hot' vs. 'cold' behavioural-cognitive styles: Motivational-dopaminergic vs. cognitive-cholinergic processing of a pavlovian cocaine cue in sign- and goal-tracking rats., The European Journal of Neuroscience, 46(11), 2768-2781. doi:10.1111/ejn.13741 [doi]
    Forkuo, A. D., Ansah, C., Pearson, D., Gertsch, W., Cirello, A., Amaral, A., . . . Rynn, C. (2017)., Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in sprague dawley rats, BMC Pharmacology & Toxicology, 18(1), 84-017-0188-8. doi:10.1186/s40360-017-0188-8 [doi]
    Frank, M. G., Barrientos, R. M., Thompson, B. M., Weber, M. D., Watkins, L. R., & Maier, S. F. (2012)., IL-1RA injected intra-cisterna magna confers extended prophylaxis against lipopolysaccharide-induced neuroinflammatory and sickness responses., Journal of Neuroimmunology, 252(1-2), 33-39. doi:10.1016/j.jneuroim.2012.07.010 [doi]
    Bakewell SJ, Carie A, Costich TL, Sethuraman J, Semple JE, Sullivan B, Martinez GV, Dominguez-Viqueira W, Sill KN., Imaging the delivery of drug-loaded, iron-stabilized micelles, Nanomedicine. 2017 May;13(4):1353-1362. doi: 10.1016/j.nano.2017.01.009. Epub 2017 Jan 20.
    Ansari, S., Freire, M. O., Pang, E. K., Abdelhamid, A. I., Almohaimeed, M., & Zadeh, H. H. (2014)., Immobilization of murine anti-BMP-2 monoclonal antibody on various biomaterials for bone tissue engineering, BioMed Research International, 2014, 940860. doi:10.1155/2014/940860 [doi]
    Ramos-Romero S, Santocildes G, Piñol-Piñol D, Rosés C, Pagés T, Hereu M, Amézqueta S, Torrella JR, Torres JL, Viscor G., Implication of gut microbiota in the physiology of rats intermittently exposed to cold and hypobaric hypoxia, PLoS One. 2020 Nov 3;15(11):e0240686. doi: 10.1371/journal.pone.0240686. eCollection 2020.
    Kojayan, Greg; Whaley, David; Alexander, Michael; Rodriguez, Samuel; Lee, Sarah; Lakey, Jonathan Rt;, Improved cryopreservation yield of pancreatic islets using combination of lower dose permeable cryoprotective agents., Cryobiology Vol.88, 2019
    Oleson S, Cox A, Liu Z, Sivasankar MP, Lu KH., In Vivo Magnetic Resonance Imaging of the Rat Vocal Folds After Systemic Dehydration and Rehydration, J Speech Lang Hear Res. 2020 Jan 10;63(1):135-142. doi: 10.1044/2019_JSLHR-19-00062. Print 2020 Jan 22.
    Masuda-Herrera MJ, Dobo KL, Kenyon MO, Kenny JD, Galloway SM, Escobar PA, Reddy MV, Jolly RA, Trejo-Martin A, Brown C, Mckeon M, Young M, Bruce S, Pant K, Dutta A, Kulkarni R, Bercu JP, In Vivo Mutagenicity Testing of Arylboronic Acids and Esters., Environ Mol Mutagen. 2019 Dec;60(9):766-777
    Hengen, K. B., Nelson, N. R., Stang, K. M., Johnson, S. M., Crader, S. M., Watters, J. J., . . . Behan, M. (2012)., Increased GABA(A) receptor epsilon-subunit expression on ventral respiratory column neurons protects breathing during pregnancy, PloS One, 7(1), e30608. doi:10.1371/journal.pone.0030608 [doi]
    Carr RL, Alugubelly N, de Leon K, Loyant L, Mohammed AN, Patterson ME, Ross MK, Rowbotham NE., Inhibition of fatty acid amide hydrolase by chlorpyrifos in juvenile rats results in altered exploratory and social behavior as adolescents, Neurotoxicology. 2020 Mar;77:127-136. doi: 10.1016/j.neuro.2020.01.002. Epub 2020 Jan 10.
    Calik, M. W., Radulovacki, M., & Carley, D. W. (2014), Intranodose ganglion injections of dronabinol attenuate serotonin-induced apnea in sprague-dawley rat., Respiratory Physiology & Neurobiology, 190, 20-24. doi:10.1016/j.resp.2013.10.001 [doi]
    West SE, Lee JC, Johns TN, Nunamaker EA., Intraperitoneal Alfaxalone and Alfaxalone-Dexmedetomidine Anesthesia in Sprague-Dawley Rats (Rattus norvegicus), J Am Assoc Lab Anim Sci. 2020 Sep 1;59(5):531-538. doi: 10.30802/AALAS-JAALAS-19-000161. Epub 2020 Aug 5.
    Moreines, J. L., Owrutsky, Z. L., & Grace, A. A. (2017), Involvement of infralimbic prefrontal cortex but not lateral habenula in dopamine attenuation after chronic mild stress., Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 42(4), 904-913. doi:10.1038/npp.2016.249 [doi]
    DeGregorio-Rocasolano, N., Marti-Sistac, O., Ponce, J., Castello-Ruiz, M., Millan, M., Guirao, V., . . . Gasull, T. (2018)., Iron-loaded transferrin (tf) is detrimental whereas iron-free tf confers protection against brain ischemia by modifying blood tf saturation and subsequent neuronal damage, Redox Biology, 15, 143-158. doi:S2213-2317(17)30801-7 [pii]
    Pais GM, Liu J, Avedissian SN, Hiner D, Xanthos T, Chalkias A, d'Aloja E, Locci E, Gilchrist A, Prozialeck WC, Rhodes NJ, Lodise TP, Fitzgerald JC, Downes KJ, Zuppa AF, Scheetz MH., Lack of synergistic nephrotoxicity between vancomycin and piperacillin/tazobactam in a rat model and a confirmatory cellular model, J Antimicrob Chemother. 2020 May 1;75(5):1228-1236. doi: 10.1093/jac/dkz563.
    Buckley, M. M., O'Brien, R., Devlin, M., Creed, A. A., Rae, M. G., Hyland, N. P., . . . O'Malley, D. (2016)., Leptin modifies the prosecretory and prokinetic effects of the inflammatory cytokine interleukin-6 on colonic function in sprague-dawley rats, Experimental Physiology, 101(12), 1477-1491. doi:10.1113/EP085917 [doi]
    Scarpace, P. J., Matheny, M., Kirichenko, N., Gao, Y. X., Tumer, N., & Zhang, Y. (2013)., Leptin overexpression in VTA trans-activates the hypothalamus whereas prolonged leptin action in either region cross-desensitizes., Neuropharmacology, 65, 90-100. doi:10.1016/j.neuropharm.2012.09.005 [doi]
    Kapphahn, Rebecca J; Richards, Michael J; Ferrington, Deborah A; Fliesler, Steven J;, Lipid-derived and other oxidative modifications of retinal proteins in a rat model of Smith-Lemli-Opitz syndrome., Experimental eye research Vol.178, 2019
    Prokai, L., Frycak, P., Nguyen, V., & Forster, M. J. (2016)., Mass spectrometric analysis of carisoprodol and meprobamate in rat brain microdialysates, Journal of Mass Spectrometry : JMS, 51(10), 900-907. doi:10.1002/jms.3799 [doi]
    Gatch MB, Forster MJ., Methylenedioxymethamphetamine-like discriminative stimulus effects of pyrrolidinyl cathinones in rats, J Psychopharmacol. 2020 Jul;34(7):778-785. doi: 10.1177/0269881120914213. Epub 2020 Jun 13.
    Gatch MB, Dolan SB, Forster MJ., Methylenedioxymethamphetamine-like discriminative stimulus effects of seven cathinones in rats, Behav Pharmacol. 2020 Jun;31(4):378-384. doi: 10.1097/FBP.0000000000000540.
    Sayadi, Lohrasb R; Alexander, Michael; Sorensen, Alexandria M; Sarantopoulos, Nikolaos; Lau, Hien; Klopfer, Michael; Ziegler, Mary E; Banyard, Derek A; Evans, Gregory R D; Lakey, Jonathan R T; Widgerow, Alan D;, Micro/nanobubbles: Improving Pancreatic Islet Cell Survival for Transplantation., Annals of plastic surgery Vol.83, 2019
    Gamble ME, Diaz MR., Moderate Adolescent Ethanol Vapor Exposure and Acute Stress in Adulthood: Sex-Dependent Effects on Social Behavior and Ethanol Intake in Sprague-Dawley Rats, Brain Sci. 2020 Nov 7;10(11):829. doi: 10.3390/brainsci10110829.
    Asok, A., Draper, A., Hoffman, A. F., Schulkin, J., Lupica, C. R., & Rosen, J. B. (2018), Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear, Molecular Psychiatry, 23(4), 914-922. doi:10.1038/mp.2017.79 [doi]
    Lazenka, M. F., & Negus, S. S. (2017), Oral modafinil facilitates intracranial self-stimulation in rats: Comparison with methylphenidate, Behavioural Pharmacology, 28(4), 318-322. doi:10.1097/FBP.0000000000000288 [doi]
    Molosh AI, Dustrude ET, Lukkes JL, Fitz SD, Caliman IF, Abreu ARR, Dietrich AD, Truitt WA, Ver Donck L, Ceusters M, Kent JM, Johnson PL, Shekhar A., Panic results in unique molecular and network changes in the amygdala that facilitate fear responses, Mol Psychiatry. 2020 Feb;25(2):442-460. doi: 10.1038/s41380-018-0119-0. Epub 2018 Aug 14.
    Miller DP, Allen MT, Servatius RJ., Partial Predictability in Avoidance Acquisition and Expression of Wistar-Kyoto and Sprague-Dawley Rats: Implications for Anxiety Vulnerability in Uncertain Situations, Front Psychiatry. 2020 Aug 19;11:848. doi: 10.3389/fpsyt.2020.00848. eCollection 2020.
    Dickmann, R. S., Strasburg, G. M., Romsos, D. R., Wilson, L. A., Lai, G. H., & Huang, H. (2016)., Particle size, surface area, and amorphous content as predictors of solubility and bioavailability for five commercial sources of ferric orthophosphate in ready-to-eat cereal, Nutrients, 8(3), 129. doi:10.3390/nu8030129 [doi]
    Sawatzke, A. B., Norris, A. W., Spyropoulos, F., Walsh, S. A., Acevedo, M. R., Hu, S., . . . Boles Ponto, L. L. (2015)., PET/CT imaging reveals unrivaled placental avidity for glucose compared to other tissues., Placenta, 36(2), 115-120. doi:10.1016/j.placenta.2014.12.009 [doi]
    Halberstadt, Adam L; Chatha, Muhammad; Klein, Adam K; McCorvy, John D; Meyer, Markus R; Wagmann, Lea; Stratford, Alexander; Brandt, Simon D;, Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD)., Neuropharmacology Vol.14, 2019
    Norwood, A. P., Al-Chaer, E. D., & Fantegrossi, W. E. (2014), Predisposing effects of neonatal visceral pain on abuse-related effects of morphine in adult male sprague dawley rats., Psychopharmacology, 231(22), 4281-4289. doi:10.1007/s00213-014-3574-6 [doi]
    Soljancic, A., Ruiz, A. L., Chandrashekar, K., Maranon, R., Liu, R., Reckelhoff, J. F., & Juncos, L. A. (2013)., Protective role of testosterone in ischemia-reperfusion-induced acute kidney injury. American Journal of Physiology, .Regulatory, Integrative and Comparative Physiology, 304(11), R951-8. doi:10.1152/ajpregu.00360.2012 [doi]
    Sills RC, Johnson GA, Anderson RJ, Johnson CL, Staup M, Brown DL, Churchill SR, Kurtz DM, Cushman JD, Waidyanatha S, Robinson VG, Cesta MF, Andrews DMK, Behl M, Shockley KR, Little PB., Qualitative and Quantitative Neuropathology Approaches Using Magnetic Resonance Microscopy (Diffusion Tensor Imaging) and Stereology in a Hexachlorophene Model of Myelinopathy in Sprague-Dawley Rats, Toxicol Pathol. 2020 Dec;48(8):965-980. doi: 10.1177/0192623320968210. Epub 2020 Dec 2.
    Vigiola Cruz M, Carney BC, Luker JN, Monger KW, Vazquez JS, Moffatt LT, Johnson LS, Shupp JW., Plasma Ameliorates Endothelial Dysfunction in Burn Injury, J Surg Res. 2019 Jan;233:459-466. doi: 10.1016/j.jss.2018.08.027. Epub 2018 Sep 22.
    Lyon, R. P., Bovee, T. D., Doronina, S. O., Burke, P. J., Hunter, J. H., Neff-LaFord, H. D., . . . Senter, P. D. (2015), Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index, Nature Biotechnology, 33(7), 733-735. doi:10.1038/nbt.3212 [doi]
    Shimada S, Abais-Battad JM, Alsheikh AJ, Yang C, Stumpf M, Kurth T, Mattson DL, Cowley AW Jr., Renal Perfusion Pressure Determines Infiltration of Leukocytes in the Kidney of Rats With Angiotensin II-Induced Hypertension, Hypertension. 2020 Sep;76(3):849-858. doi: 10.1161/HYPERTENSIONAHA.120.15295. Epub 2020 Aug 3.
    Antonilli, L., De Carolis, L., Brusadin, V., Togna, A. R., Dovizio, M., Togna, G. I., . . . Nencini, P. (2012)., Repeated exposure to codeine alters morphine glucuronidation by affecting UGT gene expression in the rat., European Journal of Pharmacology, 693(1-3), 7-14. doi:10.1016/j.ejphar.2012.07.045 [doi]
    Schalla MA, Goebel-Stengel M, Friedrich T, Kühne SG, Kobelt P, Rose M, Stengel A., Restraint stress affects circulating NUCB2/nesfatin-1 and phoenixin levels in male rats, Psychoneuroendocrinology. 2020 Dec;122:104906. doi: 10.1016/j.psyneuen.2020.104906. Epub 2020 Oct 7.
    Duan C, do Nascimento NC, Calve S, Cox A, Sivasankar MP., Restricted Water Intake Adversely Affects Rat Vocal Fold Biology, Laryngoscope. 2020 Jul 13. doi: 10.1002/lary.28881. Online ahead of print.
    Aminzadeh, M. A., Nicholas, S. B., Norris, K. C., & Vaziri, N. D. (2013)., Role of impaired Nrf2 activation in the pathogenesis of oxidative stress and inflammation in chronic tubulo-interstitial nephropathy., Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association, 28(8), 2038-2045. doi:10.1093/ndt/gft022 [doi]
    Hill K, Walker SN, Salminen A, Chung HL, Li X, Ezzat B, Miller JJ, DesOrmeaux JS, Zhang J, Hayden A, Burgin T, Piraino L, May MN, Gaborski TR, Roussie JA, Taylor J, DiVincenti L Jr, Shestopalov AA, McGrath JL, Johnson DG., Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis, Adv Healthc Mater. 2020 Feb;9(4):e1900750. doi: 10.1002/adhm.201900750. Epub 2020 Jan 15.
    Íbias J, Nazarian A., Sex differences in nicotine-induced impulsivity and its reversal with bupropion in rats, J Psychopharmacol. 2020 Dec;34(12):1382-1392. doi: 10.1177/0269881120937543. Epub 2020 Jul 20.
    Cao J, Ng M, Felmlee MA., Sex Hormones Regulate Rat Hepatic Monocarboxylate Transporter Expression and Membrane Trafficking, J Pharm Pharm Sci. 2017;20(1):435-444. doi: 10.18433/J3CH29.
    Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF., Sex, species and age: Effects of rodent demographics on the pharmacology of ∆9-tetrahydrocanabinol, Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 2;106:110064. doi: 10.1016/j.pnpbp.2020.110064. Epub 2020 Aug 15.
    Radford KD, Berman RY, Zhang M, Wu TJ, Choi KH., Sex-related differences in intravenous ketamine effects on dissociative stereotypy and antinociception in male and female rats, Pharmacol Biochem Behav. 2020 Dec;199:173042. doi: 10.1016/j.pbb.2020.173042. Epub 2020 Sep 22.
    Brzica, H., Abdullahi, W., Reilly, B. G., & Ronaldson, P. T. (2018), Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in sprague-dawley rats, Fluids and Barriers of the CNS, 15(1), 25-018-0110-9. doi:10.1186/s12987-018-0110-9 [doi]
    Huff A, Reed MD, Iceman KE, Howland DR, Pitts T., Sex-specific vagal and spinal modulation of breathing with chest compression, PLoS One. 2020 Jun 17;15(6):e0234193. doi: 10.1371/journal.pone.0234193. eCollection 2020.
    Huff A, Reed MD, Iceman KE, Howland DR, Pitts T., Sex-specific vagal and spinal modulation of swallow and its coordination with breathing, PLoS One. 2020 Jun 11;15(6):e0234194. doi: 10.1371/journal.pone.0234194. eCollection 2020.
    Gradwohl, G., Berdugo-Boura, N., Segev, Y., & Tarasiuk, A. (2015)., Sleep/Wake dynamics changes during maturation in rats., PloS One, 10(4), e0125509. doi:10.1371/journal.pone.0125509 [doi]
    Patterson, E., Marques, T. M., O'Sullivan, O., Fitzgerald, P., Fitzgerald, G. F., Cotter, P. D., . . . Ross, R. P. (2015)., Streptozotocin-induced type-1-diabetes disease onset in sprague-dawley rats is associated with an altered intestinal microbiota composition and decreased diversity., Microbiology (Reading, England), 161(Pt 1), 182-193. doi:10.1099/mic.0.082610-0 [doi]
    Jacobsen CB, Raavé R, Østergaard Pedersen M, Adumeau P, Moreau M, Valverde IE, Bjørnsdottir I, Kristensen JB, Grove MF, Raun K, McGuire J, Goncalves V, Heskamp S, Denat F, Gustafsson M., Synthesis and evaluation of zirconium-89 labelled and long-lived GLP-1 receptor agonists for PET imaging, Nucl Med Biol. 2020 Mar-Apr;82-83:49-56. doi: 10.1016/j.nucmedbio.2019.11.006. Epub 2019 Dec 4.
    Hestehave S, Abelson KSP, Brønnum Pedersen T, Munro G., The analgesic efficacy of morphine varies with rat strain and experimental pain model: implications for target validation efforts in pain drug discovery., Eur J Pain. 2019 Mar;23(3):539-554
    Larsen AT, Sonne N, Andreassen KV, Karsdal MA, Henriksen K., The Calcitonin Receptor Plays a Major Role in Glucose Regulation as a Function of Dual Amylin and Calcitonin Receptor Agonist Therapy, J Pharmacol Exp Ther. 2020 Jul;374(1):74-83. doi: 10.1124/jpet.119.263392. Epub 2020 Apr 21.
    Guo, Z. Y., Li, C. Z., Li, X. J., Wang, Y. L., Mattson, M. P., & Lu, C. B. (2013), The developmental regulation of glutamate receptor-mediated calcium signaling in primary cultured rat hippocampal neurons., Neuroreport, 24(9), 492-497. doi:10.1097/WNR.0b013e32836206b5 [doi]
    Levkovsky A, Dardik R, Barazany D, Steinberg DM, Kirichenko MD, Apter S, Peleg E, Silverberg D, Grossman E, Salomon O., The effect of civil and military flights on coagulation, fibrinolysis and blood flow: insight from a rat model, Thromb J. 2020 Oct 6;18:24. doi: 10.1186/s12959-020-00237-8. eCollection 2020.
    Ramos J, Hardin EJ, Grant AH, Flores-Robles G, Gonzalez AT, Cruz B, Martinez AK, Beltran NM, Serafine KM., The Effects of Eating a High Fat Diet on Sensitivity of Male and Female Rats to Methamphetamine and Dopamine D(1) Receptor Agonist SKF 82958, J Pharmacol Exp Ther. 2020 Jul;374(1):6-15. doi: 10.1124/jpet.119.263293. Epub 2020 Apr 7.
    Grebenstein, P. E., Thompson, I. E., & Rowland, N. E. (2013)., The effects of extended intravenous nicotine administration on body weight and meal patterns in male sprague-dawley rats, Psychopharmacology, 228(3), 359-366. doi:10.1007/s00213-013-3043-7 [doi]
    Witt EA, Reissner KJ., The effects of nicotinamide on reinstatement to cocaine seeking in male and female Sprague Dawley rats, Psychopharmacology (Berl). 2020 Mar;237(3):669-680. doi: 10.1007/s00213-019-05404-y. Epub 2019 Dec 7.
    Moran MM, Wilson BM, Li J, Engen PA, Naqib A, Green SJ, Virdi AS, Plaas A, Forsyth CB, Keshavarzian A, Sumner DR., The gut microbiota may be a novel pathogenic mechanism in loosening of orthopedic implants in rats, FASEB J. 2020 Nov;34(11):14302-14317. doi: 10.1096/fj.202001364R. Epub 2020 Sep 15.
    Gatch, M. B., Kozlenkov, A., Huang, R. Q., Yang, W., Nguyen, J. D., Gonzalez-Maeso, J., . . . Schetz, J. A. (2013)., The HIV antiretroviral drug efavirenz has LSD-like properties., Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 38(12), 2373-2384. doi:10.1038/npp.2013.135 [doi]
    Blandino, P.,Jr, Hueston, C. M., Barnum, C. J., Bishop, C., & Deak, T. (2013)., The impact of ventral noradrenergic bundle lesions on increased IL-1 in the PVN and hormonal responses to stress in male sprague dawley rats., Endocrinology, 154(7), 2489-2500. doi:10.1210/en.2013-1075 [doi]
    Zamarripa CA, Patel TR, Williams BC, Pareek T, Schrock HM, Prisinzano TE, Freeman KB., The kappa-opioid receptor agonist, nalfurafine, blocks acquisition of oxycodone self-administration and oxycodone's conditioned rewarding effects in male rats, Behav Pharmacol. 2020 Dec;31(8):792-797. doi: 10.1097/FBP.0000000000000581.
    Hanania T, Manfredi P, Inturrisi C, Vitolo OV., The N-methyl-D-aspartate receptor antagonist d-methadone acutely improves depressive-like behavior in the forced swim test performance of rats, Exp Clin Psychopharmacol. 2020 Apr;28(2):196-201. doi: 10.1037/pha0000310. Epub 2019 Aug 1.
    Walker, J. J., Spiga, F., Waite, E., Zhao, Z., Kershaw, Y., Terry, J. R., & Lightman, S. L. (2012)., The origin of glucocorticoid hormone oscillations., PLoS Biology, 10(6), e1001341. doi:10.1371/journal.pbio.1001341 [doi]
    Woodward, N. C., Levine, M. C., Haghani, A., Shirmohammadi, F., Saffari, A., Sioutas, C., . . . Finch, C. E. (2017)., Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo., Journal of Neuroinflammation, 14(1), 84-017-0858-x. doi:10.1186/s12974-017-0858-x [doi]
    Ying, W. Z., Aaron, K. J., & Sanders, P. W. (2013)., Transforming growth factor-beta regulates endothelial function during high salt intake in rats., Hypertension, 62(5), 951-956. doi:10.1161/HYPERTENSIONAHA.113.01835 [doi]
    Hu, H., Huang, N., Yi, P., Hui, Y. H., Dally, R. D., Ehlhardt, W. J., & Kulanthaivel, P. (2015), Utilizing F NMR to investigate drug disposition early in drug discovery, Xenobiotica; the Fate of Foreign Compounds in Biological Systems, , 1-11. doi:10.3109/00498254.2015.1040866 [doi]
    Tsuda MC, Mahdi S, Namchuk A, Wu TJ, Lucki I., Vendor differences in anxiety-like behaviors in female and male Sprague Dawley rats, Physiol Behav. 2020 Dec 1;227:113131. doi: 10.1016/j.physbeh.2020.113131. Epub 2020 Aug 10.
    Davidson, E. P., Coppey, L. J., Holmes, A., Lupachyk, S., Dake, B. L., Oltman, C. L., . . . Yorek, M. A. (2014)., Characterization of diabetic neuropathy in the zucker diabetic sprague-dawley rat: A new animal model for type 2 diabetes., Journal of Diabetes Research, 2014, 714273. doi:10.1155/2014/714273 [doi]
    Gotoh D, Cao N, Alexandre EC, Saito T, Morizawa Y, Hori S, Miyake M, Torimoto K, Fujimoto K, Yoshimura N., Effects of low-dose insulin or a soluble guanylate cyclase activator on lower urinary tract dysfunction in streptozotocin-induced diabetic rats, Life Sci. 2021 Dec 1;286:120001. doi: 10.1016/j.lfs.2021.120001. Epub 2021 Oct 3.
    Levine A, Liktor-Busa E, Lipinski AA, Couture S, Balasubramanian S, Aicher SA, Langlais PR, Vanderah TW, Largent-Milnes TM., Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats, Biol Sex Differ. 2021 Nov 8;12(1):60. doi: 10.1186/s13293-021-00402-2.
    Vivarelli F, Canistro D, Cirillo S, Elias RJ, Granata S, Mussoni M, Burattini S, Falcieri E, Turrini E, Fimognari C, Buschini A, Lazzaretti M, Beghi S, Girotti S, Sangiorgi S, Bolelli L, Ghini S, Ferri EN, Fagiolino I, Franchi P, Lucarini M, Mercatante D, Rodriguez-Estrada MT, Lorenzini A, Marchionni S, Gabriele M, Longo V, Paolini M., Unburned Tobacco Cigarette Smoke Alters Rat Ultrastructural Lung Airways and DNA, Nicotine Tob Res. 2021 Nov 5;23(12):2127-2134. doi: 10.1093/ntr/ntab108.
    Rakoczy R, Kamra K, Yi YJ, Wyatt C., Ethanol and opioids do not act synergistically to depress excitation in carotid body type I cells, Neuroreport. 2021 Nov 2;32(16):1307-1310. doi: 10.1097/WNR.0000000000001726.
    Krotulski AJ, Garibay N, Walther D, Walton SE, Mohr ALA, Logan BK, Baumann MH., Pharmacokinetics and pharmacodynamics of the synthetic cannabinoid, 5F-MDMB-PICA, in male rats, Neuropharmacology. 2021 Nov 1;199:108800. doi: 10.1016/j.neuropharm.2021.108800. Epub 2021 Sep 20.
    Chandler CM, Reeves-Darby J, Jones SA, Li G, Rahman MT, Cook JM, Platt DM., Modulation of relapse-like drinking in male Sprague-Dawley rats by ligands targeting the ?5GABA(A) receptor, Neuropharmacology. 2021 Nov 1;199:108785. doi: 10.1016/j.neuropharm.2021.108785. Epub 2021 Sep 10.
    Dulman RS, Auta J, Wandling GM, Patwell R, Zhang H, Pandey SC., Persistence of cerebellar ataxia during chronic ethanol exposure is associated with epigenetic up-regulation of Fmr1 gene expression in rat cerebellum, Alcohol Clin Exp Res. 2021 Oct;45(10):2006-2016. doi: 10.1111/acer.14691. Epub 2021 Aug 28.
    O'Brien R, Buckley MM, O'Malley D., Divergent effects of exendin-4 and interleukin-6 on rat colonic secretory and contractile activity are associated with changes in regional vagal afferent signaling, Neurogastroenterol Motil. 2021 Oct;33(10):e14160. doi: 10.1111/nmo.14160. Epub 2021 May 4.
    Lindholm M, Di Sabatino A, Manon-Jensen T, Mazza G, Madsen GI, Giuffrida P, Pinzani M, Krag A, Karsdal MA, Kjeldsen J, Mortensen JH., A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn's Disease and DSS Colitis, Dig Dis Sci. 2021 Sep 24. doi: 10.1007/s10620-021-07252-3. Online ahead of print.
    Ribeiro ACR, Jahr FM, Hawkins E, Kronfol MM, Younis RM, McClay JL, Deshpande LS., Epigenetic histone acetylation and Bdnf dysregulation in the hippocampus of rats exposed to repeated, low-dose diisopropylfluorophosphate, Life Sci. 2021 Sep 15;281:119765. doi: 10.1016/j.lfs.2021.119765. Epub 2021 Jun 26.
    Bennett TE, Pavek TJ, Schwark WS, Singh B., Comparison of Nociceptive Effects of Buprenorphine, Firocoxib, and Meloxicam in a Plantar Incision Model in Sprague-Dawley Rats, J Am Assoc Lab Anim Sci. 2021 Sep 1;60(5):539-548. doi: 10.30802/AALAS-JAALAS-20-000142. Epub 2021 Jul 15.
    Marsland P, Parrella A, Vore AS, Barney TM, Varlinskaya EI, Deak T., Male, but not female, Sprague Dawley rats display enhanced fear learning following acute ethanol withdrawal (hangover), Pharmacol Biochem Behav. 2021 Sep;208:173229. doi: 10.1016/j.pbb.2021.173229. Epub 2021 Jul 8.
    Hammerslag LR, Denehy ED, Carper B, Nolen TL, Prendergast MA, Bardo MT., Effects of the glucocorticoid receptor antagonist PT150 on stress-induced fentanyl seeking in male and female rats, Psychopharmacology (Berl). 2021 Sep;238(9):2439-2447. doi: 10.1007/s00213-021-05865-0. Epub 2021 May 18.
    Dunford J, Lee AT, Morgan MM., Tetrahydrocannabinol (THC) Exacerbates Inflammatory Bowel Disease in Adolescent and Adult Female Rats, J Pain. 2021 Sep;22(9):1040-1047. doi: 10.1016/j.jpain.2021.02.014. Epub 2021 Mar 13.
    Sand S., A novel method for combining outcomes with different severities or gene-level classifications, ALTEX. 2021 Aug 6. doi: 10.14573/altex.2004212. Online ahead of print.
    Groshong AM, Grassmann AA, Luthra A, McLain MA, Provatas AA, Radolf JD, Caimano MJ., PlzA is a bifunctional c-di-GMP biosensor that promotes tick and mammalian host-adaptation of Borrelia burgdorferi, PLoS Pathog. 2021 Jul 15;17(7):e1009725. doi: 10.1371/journal.ppat.1009725. eCollection 2021 Jul.
    Janssen K, Deng K, Majerus SJA, Lin DL, Hanzlicek B, Butler RS, van der Vaart CH, Damaser MS., Transurethral versus suprapubic catheterization to test urethral function in rats, Sci Rep. 2021 Jul 13;11(1):14369. doi: 10.1038/s41598-021-93772-x.
    Cata JP, Patińo M, Lacagnina MJ, Li J, Gorur A, Agudelo-Jimenez R, Wei B, Hagberg CA, Dougherty PM, Shureiqi I, Yang P, Grace PM., A rat model to investigate quality of recovery after abdominal surgery, Pain Rep. 2021 Jun 30;6(2):e943. doi: 10.1097/PR9.0000000000000943. eCollection 2021 Jul-Aug.
    Gatch MB, Shetty RA, Sumien N, Forster MJ., Behavioral effects of four novel synthetic cathinone analogs in rodents, Addict Biol. 2021 Jul;26(4):e12987. doi: 10.1111/adb.12987. Epub 2020 Nov 5.
    Gutierrez A, Nguyen JD, Creehan KM, Javadi-Paydar M, Grant Y, Taffe MA., Effects of combined THC and heroin vapor inhalation in rats, Psychopharmacology (Berl). 2021 Jun 23:1-15. doi: 10.1007/s00213-021-05904-w. Online ahead of print.
    Bries AE, Webb JL, Vogel B, Carrillo C, Keating AF, Pritchard SK, Roslan G, Miller JW, Schalinske KL., Letrozole-Induced Polycystic Ovary Syndrome Attenuates Cystathionine-? Synthase mRNA and Protein Abundance in the Ovaries of Female Sprague Dawley Rats, J Nutr. 2021 Jun 1;151(6):1407-1415. doi: 10.1093/jn/nxab038.
    Minervini V, Tye CB, Ghodrati S, France CP., Effects of remifentanil/histamine mixtures in rats responding under a choice procedure, Behav Pharmacol. 2021 Jun 1;32(4):278-285. doi: 10.1097/FBP.0000000000000610.
    Seaman RW Jr, Collins GT., Impact of Morphine Dependence and Withdrawal on the Reinforcing Effectiveness of Fentanyl, Cocaine, and Methamphetamine in Rats, Front Pharmacol. 2021 May 21;12:691700. doi: 10.3389/fphar.2021.691700. eCollection 2021.
    Ali R, Patel S, Hussain T., Angiotensin type 2 receptor activation limits kidney injury during the early phase and induces Treg cells during the late phase of renal ischemia, Am J Physiol Renal Physiol. 2021 May 1;320(5):F814-F825. doi: 10.1152/ajprenal.00507.2020. Epub 2021 Mar 15.
    Kleinveld DJB, Botros L, Maas MAW, Kers J, Aman J, Hollmann MW, Juffermans NP., Bosutinib reduces endothelial permeability and organ failure in a rat polytrauma transfusion model, Br J Anaesth. 2021 May;126(5):958-966. doi: 10.1016/j.bja.2021.01.032. Epub 2021 Mar 6.
    Stevens L, Larsen LE, Van Lysebettens W, Carrette E, Boon P, Raedt R, Vonck K., Optimized Parameters for Transducing the Locus Coeruleus Using Canine Adenovirus Type 2 (CAV2) Vector in Rats for Chemogenetic Modulation Research, Front Neurosci. 2021 Apr 13;15:663337. doi: 10.3389/fnins.2021.663337. eCollection 2021.
    Washington TA, Perry RA Jr, Kim JT, Haynie WS, Greene NP, Wolchok JC., The effect of autologous repair and voluntary wheel running on force recovery in a rat model of volumetric muscle loss, Exp Physiol. 2021 Apr;106(4):994-1004. doi: 10.1113/EP089207. Epub 2021 Mar 2.
    Zheng C, Hu Y, Sakurai M, Pinzon-Arteaga CA, Li J, Wei Y, Okamura D, Ravaux B, Barlow HR, Yu L, Sun HX, Chen EH, Gu Y, Wu J., Cell competition constitutes a barrier for interspecies chimerism, Nature. 2021 Apr;592(7853):272-276. doi: 10.1038/s41586-021-03273-0. Epub 2021 Jan 28.
    Duan C, do Nascimento NC, Calve S, Cox A, Sivasankar MP., Restricted Water Intake Adversely Affects Rat Vocal Fold Biology, Laryngoscope. 2021 Apr;131(4):839-845. doi: 10.1002/lary.28881. Epub 2020 Jul 13.
    Tchantchou F, Goodfellow M, Li F, Ramsue L, Miller C, Puche A, Fiskum G., Hyperhomocysteinemia-Induced Oxidative Stress Exacerbates Cortical Traumatic Brain Injury Outcomes in Rats, Cell Mol Neurobiol. 2021 Apr;41(3):487-503. doi: 10.1007/s10571-020-00866-7. Epub 2020 May 13.
    Boero G, Tyler RE, Todd CA, O'Buckley TK, Balan I, Besheer J, Morrow AL., (3?,5?)3-hydroxypregnan-20-one (3?,5?-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats, Neuropharmacology. 2021 Mar 15;186:108463. doi: 10.1016/j.neuropharm.2021.108463. Epub 2021 Jan 16.
    Moerke MJ, Negus SS., Temporal parameters of enhanced opioid reward after initial opioid exposure in rats, Psychopharmacology (Berl). 2021 Mar;238(3):725-734. doi: 10.1007/s00213-020-05725-3. Epub 2021 Jan 7.
    Wang L, Zhang X, Cao Y, Ma Q, Mao X, Xu J, Yang Q, Zhou Y, Lucas R, Fulton DJ, Su Y, Barman SA, Hong M, Liu Z, Huo Y., Mice with a specific deficiency of Pfkfb3 in myeloid cells are protected from hypoxia-induced pulmonary hypertension, Br J Pharmacol. 2021 Mar;178(5):1055-1072. doi: 10.1111/bph.15339. Epub 2021 Feb 1.
    Doyle MR, Sulima A, Rice KC, Collins GT., MDPV self-administration in female rats: influence of reinforcement history, Psychopharmacology (Berl). 2021 Mar;238(3):735-744. doi: 10.1007/s00213-020-05726-2. Epub 2020 Nov 24.
    Sallam HS, Li H, Chen JDZ., The Effects of Electroacupuncture via Chronically Implanted Electrodes on Alcohol Drinking and Withdrawal Signs in Rats, Neuromodulation. 2021 Feb 26. doi: 10.1111/ner.13377. Online ahead of print.
    Berthold EC, Kamble SH, Raju KS, King TI, Popa R, Sharma A, León F, Avery BA, McMahon LR, McCurdy CR., Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method, J Pharm Biomed Anal. 2021 Feb 5;194:113778. doi: 10.1016/j.jpba.2020.113778. Epub 2020 Nov 21.
    Pittenger ST, Chou S, Murawski NJ, Barrett ST, Loh O, Duque JF, Li M, Bevins RA., Female rats display higher methamphetamine-primed reinstatement and c-Fos immunoreactivity than male rats, Pharmacol Biochem Behav. 2021 Feb;201:173089. doi: 10.1016/j.pbb.2020.173089. Epub 2021 Jan 8.
    Taffe MA, Creehan KM, Vandewater SA, Kerr TM, Cole M., Effects of ??-tetrahydrocannabinol (THC) vapor inhalation in Sprague-Dawley and Wistar rats, Exp Clin Psychopharmacol. 2021 Feb;29(1):1-13. doi: 10.1037/pha0000373. Epub 2020 Apr 16.
    Tchantchou F, Miller C, Goodfellow M, Puche A, Fiskum G., Hypobaria-Induced Oxidative Stress Facilitates Homocysteine Transsulfuration and Promotes Glutathione Oxidation in Rats with Mild Traumatic Brain Injury, J Cent Nerv Syst Dis. 2021 Jan 31;13:1179573520988193. doi: 10.1177/1179573520988193. eCollection 2021.
    Liang D, Ma J, Wei B., Oral absorption and drug interaction kinetics of moxifloxacin in an animal model of weightlessness, Sci Rep. 2021 Jan 28;11(1):2605. doi: 10.1038/s41598-021-82044-3.
    McClure MJ, Olson LC, Cohen DJ, Huang YC, Zhang S, Nguyen T, Boyan BD, Schwartz Z., RNU (Foxn1 (RNU)-Nude) Rats Demonstrate an Improved Ability to Regenerate Muscle in a Volumetric Muscle Injury Compared to Sprague Dawley Rats, Bioengineering (Basel). 2021 Jan 15;8(1):12. doi: 10.3390/bioengineering8010012.
    El-Hakim Y, Mani KK, Eldouh A, Pandey S, Grimaldo MT, Dabney A, Pilla R, Sohrabji F., Sex differences in stroke outcome correspond to rapid and severe changes in gut permeability in adult Sprague-Dawley rats, Biol Sex Differ. 2021 Jan 15;12(1):14. doi: 10.1186/s13293-020-00352-1.
    Gutierrez A, Creehan KM, Taffe MA., A vapor exposure method for delivering heroin alters nociception, body temperature and spontaneous activity in female and male rats, J Neurosci Methods. 2021 Jan 15;348:108993. doi: 10.1016/j.jneumeth.2020.108993. Epub 2020 Oct 30.
    King AJ, Kohler J, Fung C, Jiang Z, Quach A, Kumaraswamy P, Chertow GM, Rosenbaum DP., Combination treatment with tenapanor and sevelamer synergistically reduces urinary phosphorus excretion in rats, Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F133-F144. doi: 10.1152/ajprenal.00137.2020. Epub 2020 Dec 7.
    Stickney JD, Morgan MM., Social housing promotes recovery of wheel running depressed by inflammatory pain and morphine withdrawal in male rats, Behav Brain Res. 2021 Jan 1;396:112912. doi: 10.1016/j.bbr.2020.112912. Epub 2020 Sep 16.
    Cox A, Cannes do Nascimento N, Pires Dos Santos A, Sivasankar MP., Dehydration and Estrous Staging in the Rat Larynx: an in vivo Prospective Investigation, J Voice. 2021 Jan;35(1):77-84. doi: 10.1016/j.jvoice.2019.06.009. Epub 2019 Jul 13.
    Liu C, Cui Z, Yan Y, Wu NL, Li L, Ying Q, Peng L., An optimized proliferation system of embryonic stem cells for generating the rat model with large fragment modification., Biochem Biophys Res Commun. 2021 Sep 24;571:8-13. doi: 10.1016/j.bbrc.2021.07.053. Epub 2021 Jul 20.
    Halperin-Sternfeld M, Pokhojaev A, Ghosh M, Rachmiel D, Kannan R, Grinberg I, Asher M, Aviv M, Ma PX, Binderman I, Sarig R, Adler-Abramovich L., Immunomodulatory fibrous hyaluronic acid-Fmoc-diphenylalanine-based hydrogel induces bone regeneration, J Clin Periodontol. 2023 Feb;50(2):200-219. doi: 10.1111/jcpe.13725. Epub 2022 Sep 27.
    Carney AE, Clarke C, Pratt WE., Administration of neuropeptide Y into the rat nucleus accumbens shell, but not core, attenuates the motivational impairment from systemic dopamine receptor antagonism by α-flupenthixol, Neurosci Lett. 2023 Jan 11;797:137069. doi: 10.1016/j.neulet.2023.137069. Online ahead of print.
    Schadt F, Israel I, Beez A, Alushi K, Weiland J, Ernestus RI, Westermaier T, Samnick S, Lilla N., Analysis of cerebral glucose metabolism following experimental subarachnoid hemorrhage over 7 days, Sci Rep. 2023 Jan 9;13(1):427. doi: 10.1038/s41598-022-26183-1.
    Abushahba F, Areid N, Gürsoy M, Willberg J, Laine V, Yatkin E, Hupa L, Närhi TO., Bioactive glass air-abrasion promotes healing around contaminated implant surfaces surrounded by circumferential bone defects: An experimental study in the rat, Clin Implant Dent Relat Res. 2023 Jan 5. doi: 10.1111/cid.13172. Online ahead of print.
    Castro AL, Frankot M, Moran TH, Iñiguez SD, Treesukosol Y., Acute and long-lasting effects of adolescent fluoxetine exposure on feeding behavior in Sprague-Dawley rats, Dev Psychobiol. 2022 Dec;64(8):e22345. doi: 10.1002/dev.22345.
    Allioux C, Achaintre L, Cheataini F, Balança B, Marinesco S., Animal welfare assessment after severe traumatic brain injury in rats, Lab Anim. 2022 Dec;56(6):528-539. doi: 10.1177/00236772221107269. Epub 2022 Aug 8.
    Sallam HS, Li H, Chen JDZ., The Effects of Electroacupuncture via Chronically Implanted Electrodes on Alcohol Drinking and Withdrawal Signs in Rats, Neuromodulation. 2022 Dec;25(8):1387-1392. doi: 10.1111/ner.13377. Epub 2022 Jun 14.
    Craft RM., Burrowing as an index of inflammatory pain in male vs. female rats, Behav Pharmacol. 2022 Nov 30:FBP.0000000000000711. doi: 10.1097/FBP.0000000000000711. Online ahead of print.
    Futatsugi K, Cabral S, Kung DW, Huard K, Lee E, Boehm M, Bauman J, Clark RW, Coffey SB, Crowley C, Dechert-Schmitt AM, Dowling MS, Dullea R, Gosset JR, Kalgutkar AS, Kou K, Li Q, Lian Y, Loria PM, Londregan AT, Niosi M, Orozco C, Pettersen JC, Pfefferkorn JA, Polivkova J, Ross TT, Sharma R, Stock IA, Tesz G, Wisniewska H, Goodwin B, Price DA., Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis, J Med Chem. 2022 Nov 24;65(22):15000-15013. doi: 10.1021/acs.jmedchem.2c01200. Epub 2022 Nov 2.
    Meariman JK, Sutphen JC, Gao J, Mercante DE, Kapusta DR., Difelikefalin, a peripherally restricted KOR (kappa opioid receptor) agonist, produces diuresis through a central KOR pathway, Pharmacol Res. 2022 Nov;185:106470. doi: 10.1016/j.phrs.2022.106470. Epub 2022 Oct 3.
    Larauche M, Erchegyi J, Miller C, Sim MS, Rivier J, Behan D, Taché Y., Peripheral CRF-R1/CRF-R2 antagonist, astressin C, induces a long-lasting blockade of acute stress-related visceral pain in male and female rats, Peptides. 2022 Nov;157:170881. doi: 10.1016/j.peptides.2022.170881. Epub 2022 Sep 19.
    Nentwig TB, Vaughan DT, Braunscheidel KM, Browning BD, Woodward JJ, Chandler LJ., The lateral habenula is not required for ethanol dependence-induced escalation of drinking, Neuropsychopharmacology. 2022 Nov;47(12):2123-2131. doi: 10.1038/s41386-022-01357-7. Epub 2022 Jun 18.
    Schwarz MM, Connors KA, Davoli KA, McMillen CM, Albe JR, Hoehl RM, Demers MJ, Ganaie SS, Price DA, Leung DW, Amarasinghe GK, McElroy AK, Reed DS, Hartman AL., Rift Valley Fever Virus Infects the Posterior Segment of the Eye and Induces Inflammation in a Rat Model of Ocular Disease, J Virol. 2022 Oct 26;96(20):e0111222. doi: 10.1128/jvi.01112-22. Epub 2022 Oct 4.
    Fico E, Rosso P, Triaca V, Segatto M, Lambiase A, Tirassa P., NGF Prevents Loss of TrkA/VEGFR2 Cells, and VEGF Isoform Dysregulation in the Retina of Adult Diabetic Rats, Cells. 2022 Oct 15;11(20):3246. doi: 10.3390/cells11203246.
    Birnie MT, Eapen AV, Kershaw YM, Lodge D, Collingridge GL, Conway-Campbell BL, Lightman SL., Time of day influences stress hormone response to ketamine, J Neuroendocrinol. 2022 Oct;34(10):e13194. doi: 10.1111/jne.13194. Epub 2022 Sep 2.
    Scott KM, Cohen DJ, Nielson DW, Kim G, Olson LC, McClure MJ, Grinstaff MW, Boyan BD, Schwartz Z., Prophylactic administration of miR-451 inhibitor decreases osteoarthritis severity in rats, Sci Rep. 2022 Sep 27;12(1):16068. doi: 10.1038/s41598-022-20415-0.
    Cristina Cardia M, Francesca Palmas M, Casula L, Pisanu A, Marceddu S, Valenti D, Sinico C, Pini E, Scerba MT, Tweedie D, Greig NH, Rosa Carta A, Lai F., Nanocrystals as an effective strategy to improve Pomalidomide bioavailability in rodent, Int J Pharm. 2022 Sep 25;625:122079. doi: 10.1016/j.ijpharm.2022.122079. Epub 2022 Aug 3.
    Kwilasz AJ, Clements MA, Larson TA, Harris KM, Litwiler ST, Woodall BJ, Todd LS, Schrama AEW, Mitten EH, Maier SF, Van Dam AM, Rice KC, Watkins LR., Involvement of TLR2-TLR4, NLRP3, and IL-17 in pain induced by a novel Sprague-Dawley rat model of experimental autoimmune encephalomyelitis, Front Pain Res (Lausanne). 2022 Sep 13;3:932530. doi: 10.3389/fpain.2022.932530. eCollection 2022.
    Corridon PR., Intravital microscopy datasets examining key nephron segments of transplanted decellularized kidneys, Sci Data. 2022 Sep 10;9(1):561. doi: 10.1038/s41597-022-01685-9.
    Getsy PM, Young AP, Bates JN, Baby SM, Seckler JM, Grossfield A, Hsieh YH, Lewis THJ, Jenkins MW, Gaston B, Lewis SJ., S-nitroso-L-cysteine stereoselectively blunts the adverse effects of morphine on breathing and arterial blood gas chemistry while promoting analgesia, Biomed Pharmacother. 2022 Sep;153:113436. doi: 10.1016/j.biopha.2022.113436. Epub 2022 Jul 26.
    Pekary AE, Sattin A., A resveratrol derivative modulates TRH and TRH-like peptide expression throughout the brain and peripheral tissues of male rats, Endocrinol Diabetes Metab. 2022 Sep;5(5):e356. doi: 10.1002/edm2.356. Epub 2022 Jul 25.
    Marciante AB, Howard J, Kelly MN, Santiago Moreno J, Allen LL, Gonzalez-Rothi EJ, Mitchell GS., Dose-dependent phosphorylation of endogenous Tau by intermittent hypoxia in rat brain, J Appl Physiol (1985). 2022 Sep 1;133(3):561-571. doi: 10.1152/japplphysiol.00332.2022. Epub 2022 Jul 21.
    Turnaturi R, Chiechio S, Pasquinucci L, Spoto S, Costanzo G, Dichiara M, Piana S, Grasso M, Amata E, Marrazzo A, Parenti C., Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain, Molecules. 2022 Aug 12;27(16):5135. doi: 10.3390/molecules27165135.
    Straathof M, Blezer ELA, Smeele CE, van Heijningen C, van der Toorn A, Buitelaar JK, Glennon JC, Otte WM, Dijkhuizen RM; TACTICS Consortium., Memantine treatment does not affect compulsive behavior or frontostriatal connectivity in an adolescent rat model for quinpirole-induced compulsive checking behavior, Psychopharmacology (Berl). 2022 Aug;239(8):2457-2470. doi: 10.1007/s00213-022-06139-z. Epub 2022 Apr 14.
    Loai S, Szulc DA, Cheng HM., Three-Dimensional Bioprinted MR-Trackable Regenerative Scaffold for Postimplantation Monitoring on T1-Weighted MRI, J Magn Reson Imaging. 2022 Aug;56(2):570-578. doi: 10.1002/jmri.28057. Epub 2022 Jan 7.
    Kalinich JF, Vergara VB, Hoffman JF., Oxidative damage in metal fragment-embedded Sprague-Dawley rat gastrocnemius muscle, Curr Res Toxicol. 2022 Jul 25;3:100083. doi: 10.1016/j.crtox.2022.100083. eCollection 2022.
    Qi S, Tan SM, Wang R, Higginbotham JA, Ritchie JL, Ibarra CK, Arguello AA, Christian RJ, Fuchs RA., Optogenetic inhibition of the dorsal hippocampus CA3 region during early-stage cocaine-memory reconsolidation disrupts subsequent context-induced cocaine seeking in rats, Neuropsychopharmacology. 2022 Jul;47(8):1473-1483. doi: 10.1038/s41386-022-01342-0. Epub 2022 May 17.
    Soliman RH, Jin C, Taylor CM, Moura Coelho da Silva E, Pollock DM., Sex Differences in Diurnal Sodium Handling During Diet-Induced Obesity in Rats, Hypertension. 2022 Jul;79(7):1395-1408. doi: 10.1161/HYPERTENSIONAHA.121.18690. Epub 2022 May 12.
    De Feo R, Manninen E, Chary K, Hämäläinen E, Immonen R, Andrade P, Ndode-Ekane XE, Gröhn O, Pitkänen A, Tohka J., Hippocampal position and orientation as prognostic biomarkers for posttraumatic epileptogenesis: An experimental study in a rat lateral fluid percussion model, Epilepsia. 2022 Jul;63(7):1849-1861. doi: 10.1111/epi.17264. Epub 2022 May 12.
    Baird TR, Akbarali HI, Dewey WL, Elder H, Kang M, Marsh SA, Peace MR, Poklis JL, Santos EJ, Negus SS., Opioid-like adverse effects of tianeptine in male rats and mice, Psychopharmacology (Berl). 2022 Jul;239(7):2187-2199. doi: 10.1007/s00213-022-06093-w. Epub 2022 Feb 24.
    Velázquez AM, Bentanachs R, Sala-Vila A, Lázaro I, Rodríguez-Morató J, Sánchez RM, Laguna JC, Roglans N, Alegret M., KHK, PNPLA3 and PPAR as Novel Targets for the Anti-Steatotic Action of Bempedoic Acid, Biomedicines. 2022 Jun 27;10(7):1517. doi: 10.3390/biomedicines10071517.
    Levis SC, Birnie MT, Bolton JL, Perrone CR, Montesinos JS, Baram TZ, Mahler SV., Enduring disruption of reward and stress circuit activities by early-life adversity in male rats, Transl Psychiatry. 2022 Jun 16;12(1):251. doi: 10.1038/s41398-022-01988-w.
    DeSantis AJ, Weche M, Enten GA, Gao X, Majetschak M., The Chemokine (C-C Motif) Receptor 2 Antagonist INCB3284 Reduces Fluid Requirements and Protects From Hemodynamic Decompensation During Resuscitation From Hemorrhagic Shock, Crit Care Explor. 2022 May 18;4(5):e0701. doi: 10.1097/CCE.0000000000000701. eCollection 2022 May.
    Ahn YH, Imaida K, Kim YB, Han KH, Pack JK, Kim N, Jeon SB, Lee AK, Choi HD, Wang J, Kawabe M, Kim HS., An International Collaborative Animal Study of the Carcinogenicity of Mobile Phone Radiofrequency Radiation: Considerations for Preparation of a Global Project, Bioelectromagnetics. 2022 May;43(4):218-224. doi: 10.1002/bem.22407. Epub 2022 Apr 27.
    Chan A, Willard A, Mulloy S, Ibrahim N, Sciaccotta A, Schonfeld M, Spencer SM., Metformin in nucleus accumbens core reduces cue-induced cocaine seeking in male and female rats, Addict Biol. 2022 May;27(3):e13165. doi: 10.1111/adb.13165.
    Ness TJ, DeWitte C, Robbins MT, DeBerry JJ., Neonatal cystitis alters mechanisms of stress-induced visceral hypersensitivity in rats, Neurosci Lett. 2022 May 1;778:136617. doi: 10.1016/j.neulet.2022.136617. Epub 2022 Apr 4.
    Pais GM, Chang J, Liu J, Scheetz MH., A translational rat model to assess glomerular function changes with vancomycin, Int J Antimicrob Agents. 2022 May;59(5):106583. doi: 10.1016/j.ijantimicag.2022.106583. Epub 2022 Apr 2.
    Barrett ST, Flynn AT, Huynh YW, Bevins RA., Appetitive Pavlovian conditioning of the stimulus effects of nicotine enhances later nicotine self-administration, J Exp Anal Behav. 2022 May;117(3):543-559. doi: 10.1002/jeab.740. Epub 2022 Feb 22.
    Gutierrez A, Nguyen JD, Creehan KM, Javadi-Paydar M, Grant Y, Taffe MA., Effects of combined THC and heroin vapor inhalation in rats, Psychopharmacology (Berl). 2022 May;239(5):1321-1335. doi: 10.1007/s00213-021-05904-w. Epub 2021 Jun 23.
    Spencer HF, Berman RY, Boese M, Zhang M, Kim SY, Radford KD, Choi KH., Effects of an intravenous ketamine infusion on inflammatory cytokine levels in male and female Sprague-Dawley rats, J Neuroinflammation. 2022 Apr 4;19(1):75. doi: 10.1186/s12974-022-02434-w.
    States GJR, Keller A, Shum-Siu A, Petruska JC, Magnuson DSK., Broad opioid antagonism amplifies disruption of locomotor function following therapy-like hindlimb stretching in spinal cord injured rats, Spinal Cord. 2022 Apr;60(4):312-319. doi: 10.1038/s41393-021-00705-6. Epub 2021 Sep 24.
    Gatch MB, Tourigny A, Shetty RA, Forster MJ., Behavioral pharmacology of five novel synthetic cannabinoids, Behav Pharmacol. 2022 Apr 1;33(2&3):175-183. doi: 10.1097/FBP.0000000000000618.
    Kline HL, Yamamoto BK., The effects of alcohol drinking on subsequent methamphetamine self-administration and relapse in adolescent female rats, Behav Brain Res. 2022 Mar 26;422:113771. doi: 10.1016/j.bbr.2022.113771. Epub 2022 Jan 24.
    Moran AE, Huynh YW, Finkner AP, Selleck C, Thompson A, Barrett ST, Bevins RA., Understanding the stimulus effects of nicotine and bupropion in a drug-drug discriminated goal-tracking task, Psychopharmacology (Berl). 2022 Mar;239(3):819-830. doi: 10.1007/s00213-022-06072-1. Epub 2022 Feb 9.
    Seaman RW Jr, Rice KC, Collins GT., Relative reinforcing effects of cocaine and 3,4-methylenedioxypyrovalerone (MDPV) under a concurrent access self-administration procedure in rats, Drug Alcohol Depend. 2022 Mar 1;232:109299. doi: 10.1016/j.drugalcdep.2022.109299. Epub 2022 Jan 12.
    Yuen J, Goyal A, Rusheen AE, Kouzani AZ, Berk M, Kim JH, Tye SJ, Blaha CD, Bennet KE, Lee KH, Oh Y, Shin H., Cocaine increases stimulation-evoked serotonin efflux in the nucleus accumbens, J Neurophysiol. 2022 Mar 1;127(3):714-724. doi: 10.1152/jn.00420.2021. Epub 2022 Jan 5.
    Flynn SM, France CP., Characterization of the Discriminative Stimulus Effects of Binary Mixtures of Mu Opioid Receptor Agonists in Rats Discriminating Fentanyl, J Pharmacol Exp Ther. 2022 Mar;380(3):171-179. doi: 10.1124/jpet.121.000912. Epub 2021 Dec 13.
    Aulehner K, Bray J, Koska I, Pace C, Palme R, Kreuzer M, Platt B, Fenzl T, Potschka H., The impact of tethered recording techniques on activity and sleep patterns in rats, Sci Rep. 2022 Feb 24;12(1):3179. doi: 10.1038/s41598-022-06307-3.
    Maya-Romero AM, Dodd GE, Landin JD, Zaremba HK, Allen OF, Bilbow MA, Hammaker RD, Santerre-Anderson JL., Adolescent high-fructose corn syrup consumption leads to dysfunction in adult affective behaviors and mesolimbic proteins in male Sprague-Dawley rats, Behav Brain Res. 2022 Feb 15;419:113687. doi: 10.1016/j.bbr.2021.113687. Epub 2021 Nov 25.
    Seaman RW Jr, Lordson C, Collins GT., Modeling Stimulant and Opioid Co-use in Rats Provided Concurrent Access to Methamphetamine and Fentanyl, Front Psychiatry. 2022 Feb 14;13:814574. doi: 10.3389/fpsyt.2022.814574. eCollection 2022.
    Radford KD, Berman RY, Jaiswal S, Kim SY, Zhang M, Spencer HF, Choi KH., Enhanced Fear Memories and Altered Brain Glucose Metabolism ((18)F-FDG-PET) following Subanesthetic Intravenous Ketamine Infusion in Female Sprague-Dawley Rats, Int J Mol Sci. 2022 Feb 8;23(3):1922. doi: 10.3390/ijms23031922.
    Carlson HN, Christensen BA, Pratt WE., Stimulation of mu opioid, but not GABAergic, receptors of the lateral habenula alters free feeding in rats, Neurosci Lett. 2022 Feb 6;771:136417. doi: 10.1016/j.neulet.2021.136417. Epub 2021 Dec 23.
    Munshi S, Ritger A, Rosenkranz AJ., Induction of Repeated Social Defeat Stress in Rats, Bio Protoc. 2022 Feb 5;12(3):e4306. doi: 10.21769/BioProtoc.4306. eCollection 2022 Feb 5.
    Quadir SG, Arleth GM, Jahad JV, Echeveste Sanchez M, Effinger DP, Herman MA., Sex differences in affective states and association with voluntary ethanol intake in Sprague-Dawley rats, Psychopharmacology (Berl). 2022 Feb;239(2):589-604. doi: 10.1007/s00213-021-06052-x. Epub 2022 Jan 19.
    Moerke MJ, Negus SS, Banks ML., Lack of effect of the nociceptin opioid peptide agonist Ro 64-6198 on pain-depressed behavior and heroin choice in rats, Drug Alcohol Depend. 2022 Feb 1;231:109255. doi: 10.1016/j.drugalcdep.2021.109255. Epub 2021 Dec 30.
    Seckler JM, Grossfield A, May WJ, Getsy PM, Lewis SJ., Nitrosyl factors play a vital role in the ventilatory depressant effects of fentanyl in unanesthetized rats, Biomed Pharmacother. 2022 Feb;146:112571. doi: 10.1016/j.biopha.2021.112571. Epub 2021 Dec 22.
    Malki M, Shapira A, Dvir T., Chondroitin sulfate-AuNRs electroactive scaffolds for on-demand release of biofactors, J Nanobiotechnology. 2022 Jan 31;20(1):59. doi: 10.1186/s12951-022-01261-8.
    Giner P, Maynez-Anchondo L, Liley AE, Uribe KP, Frietze GA, Simon NW, Mendez IA., Increased Risky Choice and Reduced CHRNB2 Expression in Adult Male Rats Exposed to Nicotine Vapor, Int J Mol Sci. 2022 Jan 22;23(3):1231. doi: 10.3390/ijms23031231.
    Friedrich T, Schalla MA, Goebel-Stengel M, Kobelt P, Rose M, Stengel A., Inflammatory Stress Induced by Intraperitoneal Injection of LPS Increases Phoenixin Expression and Activity in Distinct Rat Brain Nuclei, Brain Sci. 2022 Jan 20;12(2):135. doi: 10.3390/brainsci12020135.
    Maiti S, MaitiDutta S, Chen G., Regulations of expressions of rat/human sulfotransferases by anticancer drug, nolatrexed, and micronutrients, Anticancer Drugs. 2022 Jan 1;33(1):e525-e533. doi: 10.1097/CAD.0000000000001155.
    Nguyen JD, Creehan KM, Kerr TM, Taffe MA., Lasting effects of repeated ∆(9) -tetrahydrocannabinol vapour inhalation during adolescence in male and female rats, Br J Pharmacol. 2020 Jan;177(1):188-203. doi: 10.1111/bph.14856. Epub 2019 Oct 31.

    Immunology

    Ogura S, Baldeosingh R, Bhutto IA, Kambhampati SP, Scott McLeod D, Edwards MM, Rais R, Schubert W, Lutty GA., A role for mast cells in geographic atrophy, FASEB J. 2020 Aug;34(8):10117-10131. doi: 10.1096/fj.202000807R. Epub 2020 Jun 11.
    Tobin MK, Stephen TKL, Lopez KL, Pergande MR, Bartholomew AM, Cologna SM, Lazarov O., Activated Mesenchymal Stem Cells Induce Recovery Following Stroke Via Regulation of Inflammation and Oligodendrogenesis, J Am Heart Assoc. 2020 Apr 7;9(7):e013583. doi: 10.1161/JAHA.119.013583. Epub 2020 Mar 24.
    Kimmerling KA, Gomoll AH, Farr J, Mowry KC., Amniotic Suspension Allograft Modulates Inflammation in a Rat Pain Model of Osteoarthritis, J Orthop Res. 2020 May;38(5):1141-1149. doi: 10.1002/jor.24559. Epub 2019 Dec 19.
    Meyer DW, Bou LB, Shum S, Jonas M, Anderson ME, Hamilton JZ, Hunter JH, Wo SW, Wong AO, Okeley NM, Lyon RP., An in Vitro Assay Using Cultured Kupffer Cells Can Predict the Impact of Drug Conjugation on in Vivo Antibody Pharmacokinetics, Mol Pharm. 2020 Mar 2;17(3):802-809. doi: 10.1021/acs.molpharmaceut.9b00991. Epub 2020 Feb 5.
    Ilari S, Giancotti LA, Lauro F, Dagostino C, Gliozzi M, Malafoglia V, Sansone L, Palma E, Tafani M, Russo MA, Tomino C, Fini M, Salvemini D, Mollace V, Muscoli C., Antioxidant modulation of sirtuin 3 during acute inflammatory pain: The ROS control, Pharmacol Res. 2020 Jul;157:104851. doi: 10.1016/j.phrs.2020.104851. Epub 2020 May 11.
    Cordaro M, Siracusa R, Fusco R, D'Amico R, Peritore AF, Gugliandolo E, Genovese T, Scuto M, Crupi R, Mandalari G, Cuzzocrea S, Di Paola R, Impellizzeri D., Cashew (Anacardium occidentale L.) Nuts Counteract Oxidative Stress and Inflammation in an Acute Experimental Model of Carrageenan-Induced Paw Edema, Antioxidants (Basel). 2020 Jul 24;9(8):660. doi: 10.3390/antiox9080660.
    Smith TA, Ghergherehchi CL, Tucker HO, Bittner GD., Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts, J Neuroinflammation. 2020 Oct 2;17(1):287. doi: 10.1186/s12974-020-01953-8.
    Loupy KM, Cler KE, Marquart BM, Yifru TW, D'Angelo HM, Arnold MR, Elsayed AI, Gebert MJ, Fierer N, Fonken LK, Frank MG, Zambrano CA, Maier SF, Lowry CA., Comparing the effects of two different strains of mycobacteria, Mycobacterium vaccae NCTC 11659 and M. vaccae ATCC 15483, on stress-resilient behaviors and lipid-immune signaling in rats, Brain Behav Immun. 2021 Jan;91:212-229. doi: 10.1016/j.bbi.2020.09.030. Epub 2020 Oct 1.
    Smith ZZ, Kubiak RA, Arnold MR, Loupy KM, Taylor JA, Crist TG, Bernier AE, D'Angelo HM, Heinze JD, Lowry CA, Barth DS., Effects of immunization with heat-killed Mycobacterium vaccae on autism spectrum disorder-like behavior and epileptogenesis in a rat model of comorbid autism and epilepsy, Brain Behav Immun. 2020 Aug;88:763-780. doi: 10.1016/j.bbi.2020.05.034. Epub 2020 May 19.
    Hakami Z, Hand AR., Expression of aquaporin 5 during murine palatine glands development: a light and electron microscopic immunocytochemical study, Eur J Oral Sci. 2020 Oct;128(5):379-385. doi: 10.1111/eos.12734. Epub 2020 Aug 19.
    Ezeomah C, Cunningham KA, Stutz SJ, Fox RG, Bukreyeva N, Dineley KT, Paessler S, Cisneros IE., Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats, Brain Behav Immun. 2020 Jul;87:725-738. doi: 10.1016/j.bbi.2020.03.003. Epub 2020 Mar 9.
    Belanger KM, Crislip GR, Gillis EE, Abdelbary M, Musall JB, Mohamed R, Baban B, Elmarakby A, Brands MW, Sullivan JC., Greater T Regulatory Cells in Females Attenuate DOCA-Salt-Induced Increases in Blood Pressure Versus Males, Hypertension. 2020 Jun;75(6):1615-1623. doi: 10.1161/HYPERTENSIONAHA.119.14089. Epub 2020 Apr 27.
    Metzger CE, Anand Narayanan S, Phan PH, Bloomfield SA., Hindlimb unloading causes regional loading-dependent changes in osteocyte inflammatory cytokines that are modulated by exogenous irisin treatment, NPJ Microgravity. 2020 Oct 7;6:28. doi: 10.1038/s41526-020-00118-4. eCollection 2020.
    Ramirez LA, Gillis EE, Musall JB, Mohamed R, Snyder E, El-Marakby A, Sullivan JC., Hypertensive female Sprague-Dawley rats require an intact nitric oxide synthase system for compensatory increases in renal regulatory T cells, Am J Physiol Renal Physiol. 2020 Aug 1;319(2):F192-F201. doi: 10.1152/ajprenal.00228.2020. Epub 2020 Jun 29.
    Morales W, Triantafyllou K, Parodi G, Weitsman S, Park SC, Rezaie A, Pichetshote N, Lin E, Pimentel M., Immunization with cytolethal distending toxin B produces autoantibodies to vinculin and small bowel bacterial changes in a rat model of postinfectious irritable bowel syndrome, Neurogastroenterol Motil. 2020 Oct;32(10):e13875. doi: 10.1111/nmo.13875. Epub 2020 May 21.
    Cornelius DC, Travis OK, Tramel RW, Borges-Rodriguez M, Baik CH, Greer M, Giachelli CA, Tardo GA, Williams JM., NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture, PLoS One. 2020 Jun 17;15(6):e0234039. doi: 10.1371/journal.pone.0234039. eCollection 2020.
    Litvin DG, Denstaedt SJ, Borkowski LF, Nichols NL, Dick TE, Smith CB, Jacono FJ., Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats, Brain Behav Immun. 2020 Jul;87:610-633. doi: 10.1016/j.bbi.2020.02.006. Epub 2020 Feb 22.
    Smith TA, Ghergherehchi CL, Mikesh M, Shores JT, Tucker HO, Bittner GD., Polyethylene glycol-fusion repair of sciatic allografts in female rats achieves immunotolerance via attenuated innate and adaptive responses, J Neurosci Res. 2020 Dec;98(12):2468-2495. doi: 10.1002/jnr.24720. Epub 2020 Sep 15.
    Munshi S, Loh MK, Ferrara N, DeJoseph MR, Ritger A, Padival M, Record MJ, Urban JH, Rosenkranz JA., Repeated stress induces a pro-inflammatory state, increases amygdala neuronal and microglial activation, and causes anxiety in adult male rats, Brain Behav Immun. 2020 Feb;84:180-199. doi: 10.1016/j.bbi.2019.11.023. Epub 2019 Nov 27.
    Worth AA, Shoop R, Tye K, Feetham CH, D'Agostino G, Dodd GT, Reimann F, Gribble FM, Beebe EC, Dunbar JD, Alexander-Chacko JT, Sindelar DK, Coskun T, Emmerson PJ, Luckman SM., The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling, Elife. 2020 Jul 29;9:e55164. doi: 10.7554/eLife.55164.
    Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, Wen L, Husain SZ, Sugar CA, Roos J, Ramos S, Lugea A, Dunn M, Stauderman K, Pandol SJ., The Orai Ca(2+) channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis, J Physiol. 2019 Jun;597(12):3085-3105. doi: 10.1113/JP277856. Epub 2019 May 22.
    Ellison TJ, Talbott GC, Henderson DR., VaxiPatch™, a novel vaccination system comprised of subunit antigens, adjuvants and microneedle skin delivery: An application to influenza B/Colorado/06/2017, Vaccine. 2020 Oct 7;38(43):6839-6848. doi: 10.1016/j.vaccine.2020.07.040. Epub 2020 Jul 31.

    Infectious disease

    Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R., SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia, Pain. 2020 Oct 1. doi: 10.1097/j.pain.0000000000002097. Online ahead of print.
    Zhao M, Zhang F, Zarnowski R, Barns K, Jones R, Fossen J, Sanchez H, Rajski SR, Audhya A, Bugni TS, Andes DR., Turbinmicin inhibits Candida biofilm growth by disrupting fungal vesicle-mediated trafficking, J Clin Invest. 2021 Mar 1;131(5):e145123. doi: 10.1172/JCI145123.

    Metabolism

    Cladis DP, Simpson AMR, Cooper KJ, Nakatsu CH, Ferruzzi MG, Weaver CM., Blueberry polyphenols alter gut microbiota & phenolic metabolism in rats., Food Funct. 2021 Mar 21;12(6):2442-2456. doi: 10.1039/d0fo03457f. Epub 2021 Feb 25.

    Neurology

    Bloms-Funke P, Bankstahl M, Bankstahl J, Kneip C, Schröder W, Löscher W., The novel dual-mechanism Kv7 potassium channel/TSPO receptor activator GRT-X is more effective than the Kv7 channel opener retigabine in the 6-Hz refractory seizure mouse model, Neuropharmacology. 2022 Feb 1;203:108884. doi: 10.1016/j.neuropharm.2021.108884. Epub 2021 Nov 14.
    Zhang M, Spencer HF, Berman RY, Radford KD, Choi KH., Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats, IBRO Neurosci Rep. 2021 Jul 3;11:42-51. doi: 10.1016/j.ibneur.2021.06.005. eCollection 2021 Dec.
    Elabi OF, Davies JS, Lane EL., L-dopa-Dependent Effects of GLP-1R Agonists on the Survival of Dopaminergic Cells Transplanted into a Rat Model of Parkinson Disease, Int J Mol Sci. 2021 Nov 16;22(22):12346. doi: 10.3390/ijms222212346.
    Thakre PP, Sunshine MD, Fuller DD., Spinally delivered ampakine CX717 increases phrenic motor output in adult rats, Respir Physiol Neurobiol. 2021 Nov 11;296:103814. doi: 10.1016/j.resp.2021.103814. Online ahead of print.
    Ferrara NC, Trask S, Avonts B, Loh MK, Padival M, Rosenkranz JA., Developmental Shifts in Amygdala Activity during a High Social Drive State, J Neurosci. 2021 Nov 10;41(45):9308-9325. doi: 10.1523/JNEUROSCI.1414-21.2021. Epub 2021 Oct 5.
    Shafiei-Irannejad V, Abbaszadeh S, Janssen PML, Soraya H., Memantine and its benefits for cancer, cardiovascular and neurological disorders, Eur J Pharmacol. 2021 Nov 5;910:174455. doi: 10.1016/j.ejphar.2021.174455. Epub 2021 Aug 27.
    Nalamolu KR, Challa SR, Fornal CA, Grudzien NA, Jorgenson LC, Choudry MM, Smith NJ, Palmer CJ, Pinson DM, Klopfenstein JD, Veeravalli KK., Attenuation of the Induction of TLRs 2 and 4 Mitigates Inflammation and Promotes Neurological Recovery After Focal Cerebral Ischemia, Transl Stroke Res. 2021 Oct;12(5):923-936. doi: 10.1007/s12975-020-00884-z. Epub 2021 Jan 11.
    Race NS, Andrews KD, Lungwitz EA, Vega Alvarez SM, Warner TR, Acosta G, Cao J, Lu KH, Liu Z, Dietrich AD, Majumdar S, Shekhar A, Truitt WA, Shi R., Psychosocial impairment following mild blast-induced traumatic brain injury in rats, Behav Brain Res. 2021 Aug 27;412:113405. doi: 10.1016/j.bbr.2021.113405. Epub 2021 Jun 23.
    Gwak YS, Chen G, Abdi S, Kim HK., Calcium-independent phospholipase A2 inhibitor produces an analgesic effect in a rat model of neuropathic pain by reducing central sensitization in the dorsal horn, Neurol Res. 2021 Aug;43(8):683-692. doi: 10.1080/01616412.2021.1915079. Epub 2021 Apr 18.
    Shakil S, Masjoan Juncos JX, Mariappan N, Zafar I, Amudhan A, Amudhan A, Aishah D, Siddiqui S, Manzoor S, Santana CM, Rumbeiha WK, Salim S, Ahmad A, Ahmad S., Behavioral and Neuronal Effects of Inhaled Bromine Gas: Oxidative Brain Stem Damage, Int J Mol Sci. 2021 Jun 12;22(12):6316. doi: 10.3390/ijms22126316.
    Wahlstrom KL, Alvarez-Dieppa AC, McIntyre CK, LaLumiere RT., The medial entorhinal cortex mediates basolateral amygdala effects on spatial memory and downstream activity-regulated cytoskeletal-associated protein expression, Neuropsychopharmacology. 2021 May;46(6):1172-1182. doi: 10.1038/s41386-020-00875-6. Epub 2020 Oct 2.
    Ciesla MC, Seven YB, Allen LL, Smith KN, Asa ZA, Simon AK, Holland AE, Santiago JV, Stefan K, Ross A, Gonzalez-Rothi EJ, Mitchell GS., Serotonergic innervation of respiratory motor nuclei after cervical spinal injury: Impact of intermittent hypoxia, Exp Neurol. 2021 Apr;338:113609. doi: 10.1016/j.expneurol.2021.113609. Epub 2021 Jan 15.
    Martelle SE, Cotella EM, Nawreen N, Chen C, Packard BA, Fitzgerald M, Herman JP., Prefrontal cortex PACAP signaling: organization and role in stress regulation, Stress. 2021 Mar;24(2):196-205. doi: 10.1080/10253890.2021.1887849. Epub 2021 Mar 17.
    Goossens MG, Boon P, Wadman W, Van den Haute C, Baekelandt V, Verstraete AG, Vonck K, Larsen LE, Sprengers M, Carrette E, Desloovere J, Meurs A, Delbeke J, Vanhove C, Raedt R., Long-term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy, Epilepsia. 2021 Mar;62(3):659-670. doi: 10.1111/epi.16840. Epub 2021 Feb 11.
    Dore K, Malinow R., Elevated PSD-95 Blocks Ion-flux Independent LTD: A Potential New Role for PSD-95 in Synaptic Plasticity, Neuroscience. 2021 Feb 21;456:43-49. doi: 10.1016/j.neuroscience.2020.02.020. Epub 2020 Feb 28.
    Dela Peńa I, Shen G, Shi WX., Droxidopa alters dopamine neuron and prefrontal cortex activity and improves attention-deficit/hyperactivity disorder-like behaviors in rats, Eur J Pharmacol. 2021 Feb 5;892:173826. doi: 10.1016/j.ejphar.2020.173826. Epub 2020 Dec 19.
    Kim HK, Bae J, Lee SH, Hwang SH, Kim MS, Kim MJ, Jun S, Cervantes CL, Jung YS, Back S, Lee H, Lee SE, Dougherty PM, Lee SW, Park JI, Abdi S., Blockers of Wnt3a, Wnt10a, or ?-Catenin Prevent Chemotherapy-Induced Neuropathic Pain In Vivo, Neurotherapeutics. 2021 Jan;18(1):601-614. doi: 10.1007/s13311-020-00956-w. Epub 2020 Oct 30.
    Lacagnina MJ, Li J, Lorca S, Rice KC, Sullivan K, O'Callaghan JP, Grace PM., A role for neuroimmune signaling in a rat model of Gulf War Illness-related pain, Brain Behav Immun. 2021 Jan;91:418-428. doi: 10.1016/j.bbi.2020.10.022. Epub 2020 Oct 27.
    Hu X, Yan J, Huang L, Araujo C, Peng J, Gao L, Liu S, Tang J, Zuo G, Zhang JH., INT-777 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TGR5/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats, Brain Behav Immun. 2021 Jan;91:587-600. doi: 10.1016/j.bbi.2020.09.016. Epub 2020 Sep 19.
    Vazquez-Sanroman DB, Arlington Wilson G, Bardo MT., Effects of Social Isolation on Perineuronal Nets in the Amygdala Following a Reward Omission Task in Female Rats, Mol Neurobiol. 2021 Jan;58(1):348-361. doi: 10.1007/s12035-020-02125-8. Epub 2020 Sep 17.
    Brigande AM, Darwich JG, Currie PJ., Mesolimbic exendin-4 attenuates reward salience evoked by neuropeptide Y and ghrelin, Behav Brain Res. 2023 Feb 25;440:114249. doi: 10.1016/j.bbr.2022.114249. Epub 2022 Dec 7.
    Carney AE, Clarke C, Pratt WE., Administration of neuropeptide Y into the rat nucleus accumbens shell, but not core, attenuates the motivational impairment from systemic dopamine receptor antagonism by α-flupenthixol, Neurosci Lett. 2023 Jan 11;797:137069. doi: 10.1016/j.neulet.2023.137069. Online ahead of print.
    Biose IJ, Chastain WH, Wang H, Ouvrier B, Bix GJ., Optimizing intraluminal monofilament model of ischemic stroke in middle-aged Sprague-Dawley rats, BMC Neurosci. 2022 Dec 9;23(1):75. doi: 10.1186/s12868-022-00764-2.
    Patterson FM, Miralami R, Olivier AK, McNulty K, Wood JW, Prabhu RK, Priddy LB., Increase in serum nerve growth factor but not intervertebral disc degeneration following whole-body vibration in rats, Clin Biomech (Bristol, Avon). 2022 Dec;100:105823. doi: 10.1016/j.clinbiomech.2022.105823. Epub 2022 Nov 18.
    Hyder SK, Ghosh A, Forcelli PA., Optogenetic activation of the superior colliculus attenuates spontaneous seizures in the pilocarpine model of temporal lobe epilepsy, Epilepsia. 2022 Nov 30. doi: 10.1111/epi.17469. Online ahead of print.
    Scott MC, Haase CM, Olson SD, Cox CS Jr., Dexmedetomidine Alters the Inflammatory Profile of Rat Microglia In Vitro, Neurocrit Care. 2022 Nov 23. doi: 10.1007/s12028-022-01638-5. Online ahead of print.
    Lehtonen SM, Waselius T, Penttonen M, Nokia MS., Hippocampal responses to electrical stimulation of the major input pathways are modulated by dentate spikes, Hippocampus. 2022 Nov;32(11-12):808-817. doi: 10.1002/hipo.23470. Epub 2022 Sep 16.
    Stanton JA, Williams EI, Betterton RD, Davis TP, Ronaldson PT., Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats, Exp Neurol. 2022 Nov;357:114181. doi: 10.1016/j.expneurol.2022.114181. Epub 2022 Jul 26.
    Challa SR, Nalamolu KR, Fornal CA, Wang BC, Martin RC, Olson EA, Ujjainwala AL, Pinson DM, Klopfenstein JD, Veeravalli KK., Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration, Front Neurosci. 2022 Oct 4;16:1012812. doi: 10.3389/fnins.2022.1012812. eCollection 2022.
    Lillyman DJ, Lee FS, Barnett EC, Miller TJ, Alvaro ML, Drvol HC, Wachs RA., Axial hypersensitivity is associated with aberrant nerve sprouting in a novel model of disc degeneration in female Sprague Dawley rats, JOR Spine. 2022 Jul 14;5(3):e1212. doi: 10.1002/jsp2.1212. eCollection 2022 Sep.
    Thacker JS, Mielke JG., The combined effects of corticosterone and brain-derived neurotrophic factor on plasticity-related receptor phosphorylation and expression at the synaptic surface in male Sprague-Dawley rats, Horm Behav. 2022 Sep;145:105233. doi: 10.1016/j.yhbeh.2022.105233. Epub 2022 Jul 22.
    Schreiber R, Campbell U, Quinton MS, Hardy LW, Fang QK, Lew R., In vitro and in vivo pharmacological characterization of dasotraline, a dual dopamine and norepinephrine transporter inhibitor in vivo, Biomed Pharmacother. 2022 Sep;153:113359. doi: 10.1016/j.biopha.2022.113359. Epub 2022 Jul 1.
    Boero G, Tyler RE, O'Buckley TK, Balan I, Besheer J, Morrow AL., (3α,5α)3-Hydroxypregnan-20-one (3α,5α-THP) Regulation of the HPA Axis in the Context of Different Stressors and Sex, Biomolecules. 2022 Aug 18;12(8):1134. doi: 10.3390/biom12081134.
    McCoy AM, Prevot TD, Mian MY, Cook JM, Frazer A, Sibille EL, Carreno FR, Lodge DJ., Positive Allosteric Modulation of α5-GABAA Receptors Reverses Stress-Induced Alterations in Dopamine System Function and Prepulse Inhibition of Startle, Int J Neuropsychopharmacol. 2022 Aug 16;25(8):688-698. doi: 10.1093/ijnp/pyac035.
    Jawaid S, Herring AI, Getsy PM, Lewis SJ, Watanabe M, Kolesova H., Differential immunostaining patterns of transient receptor potential (TRP) ion channels in the rat nodose ganglion, J Anat. 2022 Aug;241(2):230-244. doi: 10.1111/joa.13656. Epub 2022 Apr 9.
    Marsland P, Parrella A, Orlofsky M, Lovelock DF, Vore AS, Varlinskaya EI, Deak T., Neuroendocrine and neuroimmune responses in male and female rats: evidence for functional immaturity of the neuroimmune system during early adolescence, Eur J Neurosci. 2022 May;55(9-10):2311-2325. doi: 10.1111/ejn.15118. Epub 2021 Feb 7.
    Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT., High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats, Pharmaceutics. 2022 Apr 27;14(5):949. doi: 10.3390/pharmaceutics14050949.
    Goins AE, Gomez K, Ran D, Afaghpour-Becklund M, Khanna R, Alles SRA., Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain, Pflugers Arch. 2022 Apr;474(4):397-403. doi: 10.1007/s00424-021-02653-9. Epub 2022 Jan 20.
    Hughey S, Campbell D, Rapp-Santos K, Cole J, Booth G, Longwell J, Stedje-Larsen E., Refining the rat sciatic nerve block: a novel ultrasound-guided technique, Lab Anim. 2022 Apr;56(2):191-195. doi: 10.1177/00236772211034627. Epub 2021 Aug 1.
    Gore AC, Moore T, Groom MJ, Thompson LM., Prenatal Exposure to an EDC Mixture, NeuroMix: Effects on Brain, Behavior, and Stress Responsiveness in Rats, Toxics. 2022 Mar 3;10(3):122. doi: 10.3390/toxics10030122.
    Hoogland G, Raijmakers M, Clynen E, Brône B, Rigo JM, Swijsen A., Experimental early-life febrile seizures cause a sustained increase in excitatory neurotransmission in newborn dentate granule cells, Brain Behav. 2022 Mar;12(3):e2505. doi: 10.1002/brb3.2505. Epub 2022 Feb 22.
    Pekary AE, Sattin A., Rifaximin modulates TRH and TRH-like peptide expression throughout the brain and peripheral tissues of male rats, BMC Neurosci. 2022 Feb 21;23(1):9. doi: 10.1186/s12868-022-00694-z.
    Malone IG, Kelly MN, Nosacka RL, Nash MA, Yue S, Xue W, Otto KJ, Dale EA., Closed-Loop, Cervical, Epidural Stimulation Elicits Respiratory Neuroplasticity after Spinal Cord Injury in Freely Behaving Rats, eNeuro. 2022 Feb 9;9(1):ENEURO.0426-21.2021. doi: 10.1523/ENEURO.0426-21.2021. Print 2022 Jan-Feb.
    Thakre PP, Sunshine MD, Fuller DD., Spinally delivered ampakine CX717 increases phrenic motor output in adult rats, Respir Physiol Neurobiol. 2022 Feb;296:103814. doi: 10.1016/j.resp.2021.103814. Epub 2021 Nov 11.
    Hyppönen V, Stenroos P, Nivajärvi R, Ardenkjaer-Larsen JH, Gröhn O, Paasonen J, Kettunen MI., Metabolism of hyperpolarised [1-(13) C]pyruvate in awake and anaesthetised rat brains, NMR Biomed. 2022 Feb;35(2):e4635. doi: 10.1002/nbm.4635. Epub 2021 Oct 21.
    Ness TJ, DeWitte C, DeBerry JJ., Spinal neurochemical mechanisms of acute stress-induced visceral hypersensitivity in healthy rats, Neurosci Lett. 2022 Jan 23;770:136401. doi: 10.1016/j.neulet.2021.136401. Epub 2021 Dec 17.
    Trecarichi A, Duggett NA, Granat L, Lo S, Malik AN, Zuliani-Álvarez L, Flatters SJL., Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy, PLoS One. 2022 Jan 11;17(1):e0262544. doi: 10.1371/journal.pone.0262544. eCollection 2022.
    Ramos MD, Briyal S, Prazad P, Gulati A., Neuroprotective Effect of Sovateltide (IRL 1620, PMZ 1620) in a Neonatal Rat Model of Hypoxic-Ischemic Encephalopathy, Neuroscience. 2022 Jan 1;480:194-202. doi: 10.1016/j.neuroscience.2021.11.027. Epub 2021 Nov 23.
    Walter LA, Blake LP, Gallot YS, Arends CJ, Sozio RS, Onifer SM, Bohnert KR., Effect of Denervation on XBP1 in Skeletal Muscle and the Neuromuscular Junction, Int J Mol Sci. 2021 Dec 24;23(1):169. doi: 10.3390/ijms23010169.
    Gill KM, Cook JM, Poe MM, Grace AA., Prior antipsychotic drug treatment prevents response to novel antipsychotic agent in the methylazoxymethanol acetate model of schizophrenia, Schizophr Bull. 2014 Mar;40(2):341-50. doi: 10.1093/schbul/sbt236. Epub 2014 Jan 24.

    Neuroscience

    Benmansour, S., Arroyo, L. D., & Frazer, A. (2016)., Comparison of the antidepressant-like effects of estradiol and that of selective serotonin reuptake inhibitors in middle-aged ovariectomized rats., Frontiers in Aging Neuroscience, 8, 311. doi:10.3389/fnagi.2016.00311 [doi]
    Ji Y, Hu B, Klontz C, Li J, Dessem D, Dorsey SG, Traub RJ., Peripheral mechanisms contribute to comorbid visceral hypersensitivity induced by preexisting orofacial pain and stress in female rats, Neurogastroenterol Motil. 2020 Jul;32(7):e13833. doi: 10.1111/nmo.13833. Epub 2020 Mar 10.
    Hay M, Polt R, Heien ML, Vanderah TW, Largent-Milnes TM, Rodgers K, Falk T, Bartlett MJ, Doyle KP, Konhilas JP., A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction, J Pharmacol Exp Ther. 2019 Apr;369(1):9-25. doi: 10.1124/jpet.118.254854. Epub 2019 Feb 1.
    Wright DM, Small KM, Nag S, Mokha SS., Activation of Membrane Estrogen Receptors Attenuates NOP-Mediated Tactile Antihypersensitivity in a Rodent Model of Neuropathic Pain, Brain Sci. 2019 Jun 21;9(6):147. doi: 10.3390/brainsci9060147.
    Anwer, Mehwish; Lara-Valderrabano, Leonardo; Karttunen, Jenni; Ndode-Ekane, Xavier Ekolle; Puhakka, Noora; Pitkänen, Asla;, Acute Downregulation of Novel Hypothalamic Protein Sushi Repeat-Containing Protein X-Linked 2 after Experimental Traumatic Brain Injury., Journal of neurotrauma Vol., 2019
    Mathot F, Rbia N, Bishop AT, Hovius SER, Shin AY., Adipose derived mesenchymal stem cells seeded onto a decellularized nerve allograft enhances angiogenesis in a rat sciatic nerve defect model, Microsurgery. 2020 Jul;40(5):585-592. doi: 10.1002/micr.30579. Epub 2020 Mar 31.
    Irwin, R. W., Solinsky, C. M., Loya, C. M., Salituro, F. G., Rodgers, K. E., Bauer, G., . . . Brinton, R. D. (2015)., Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for alzheimer's disease., PloS One, 10(6), e0128313. doi:10.1371/journal.pone.0128313 [doi]
    Guo, Wei; Imai, Satoshi; Zou, Shiping; Yang, Jiale; Watanabe, Mineo; Wang, Jing; Dubner, Ronald; Wei, Feng; Ren, Ke;, Altered glial glutamate transporter expression in descending circuitry and the emergence of pain chronicity, Molecular pain Vol.15,
    Gargiulo AT, Li X, Grafe LA., Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm, J Vis Exp. 2020 May 4;(159). doi: 10.3791/61228.
    Martinez D, Rogers RC, Hermann GE, Hasser EM, Kline DD., Astrocytic glutamate transporters reduce the neuronal and physiological influence of metabotropic glutamate receptors in nucleus tractus solitarii, Am J Physiol Regul Integr Comp Physiol. 2020 Mar 1;318(3):R545-R564. doi: 10.1152/ajpregu.00319.2019. Epub 2020 Jan 22.
    ChĂĄvez-Pichardo ME, Reyes-Bravo DY, Mendoza-Trejo MS, MarĂ­n-LĂłpez AG, Giordano M, HernĂĄndez-Chan N, DomĂ­nguez-Marchan K, Ortega-Rosales LC, RodrĂ­guez VM., Brain alterations in GABA, glutamate and glutamine markers after chronic atrazine exposure in the male albino rat, Arch Toxicol. 2020 Sep;94(9):3217-3230. doi: 10.1007/s00204-020-02806-2. Epub 2020 Jun 19.
    Newsom, R. J., Osterlund, C., Masini, C. V., Day, H. E., Spencer, R. L., & Campeau, S. (2012, Cannabinoid receptor type 1 antagonism significantly modulates basal and loud noise induced neural and hypothalamic-pituitary-adrenal axis responses in male sprague-dawley rats., Neuroscience, 204, 64-73. doi:10.1016/j.neuroscience.2011.11.043 [doi]
    Gamdzyk M, Doycheva DM, Araujo C, Ocak U, Luo Y, Tang J, Zhang JH., cGAS/STING Pathway Activation Contributes to Delayed Neurodegeneration in Neonatal Hypoxia-Ischemia Rat Model: Possible Involvement of LINE-1, Mol Neurobiol. 2020 Jun;57(6):2600-2619. doi: 10.1007/s12035-020-01904-7. Epub 2020 Apr 6.
    Hoffman JR, Zuckerman A, Ram O, Sadot O, Cohen H., Changes in Hippocampal Androgen Receptor Density and Behavior in Sprague-Dawley Male Rats Exposed to a Low-Pressure Blast Wave, Brain Plast. 2020 Oct 1;5(2):135-145. doi: 10.3233/BPL-200107.
    Phillips, K. F., & Deshpande, L. S. (2018)., Chronic neurological morbidities and elevated hippocampal calcium levels in a DFP-based rat model of gulf war illness., Military Medicine, 183(suppl_1), 552-555. doi:10.1093/milmed/usx148 [doi]
    Pitts EG, Stowe TA, Christensen BA, Ferris MJ., Comparing dopamine release, uptake, and D2 autoreceptor function across the ventromedial to dorsolateral striatum in adolescent and adult male and female rats, Neuropharmacology. 2020 Sep 15;175:108163. doi: 10.1016/j.neuropharm.2020.108163. Epub 2020 May 29.
    Navarrete-Opazo, A., Vinit, S., Dougherty, B. J., & Mitchell, G. S. (2015)., Daily acute intermittent hypoxia elicits functional recovery of diaphragm and inspiratory intercostal muscle activity after acute cervical spinal injury., Experimental Neurology, 266, 1-10. doi:10.1016/j.expneurol.2015.02.007 [doi]
    Mychasiuk, R., Hehar, H., van Waes, L., & Esser, M. J. (2015), Diet, age, and prior injury status differentially alter behavioral outcomes following concussion in rats., . Neurobiology of Disease, 73, 1-11. doi:10.1016/j.nbd.2014.09.003 [doi]
    Maliszewski-Hall, A. M., Alexander, M., Tkac, I., Oz, G., & Rao, R. (2015)., Differential effects of intrauterine growth restriction on the regional neurochemical profile of the developing rat brain, Neurochemical Research, doi:10.1007/s11064-015-1609-y [doi]
    Yang W, Munhall AC, Johnson SW., Dopamine Evokes a Trace Amine Receptor-dependent Inward Current that is Regulated by AMP Kinase in Substantia Nigra Dopamine Neurons, Neuroscience. 2020 Feb 10;427:77-91. doi: 10.1016/j.neuroscience.2019.11.044. Epub 2019 Dec 26.
    Sanna F, Bratzu J, Piludu MA, Corda MG, Melis MR, Giorgi O, Argiolas A., Dopamine, Noradrenaline and Differences in Sexual Behavior between Roman High and Low Avoidance Male Rats: A Microdialysis Study in the Medial Prefrontal Cortex, Front Behav Neurosci. 2017 Jun 7;11:108. doi: 10.3389/fnbeh.2017.00108. eCollection 2017.
    Hartrick CT, Poulin D, Molenaar R, Hartrick A., Dual-Acting Peripherally Restricted Delta/Kappa Opioid (CAV1001) Produces Antinociception in Animal Models of Sub-Acute and Chronic Pain, J Pain Res. 2020 Oct 6;13:2461-2474. doi: 10.2147/JPR.S262303. eCollection 2020.
    Martha SR, Collier LA, Davis SM, Goodwin SJ, Powell D, Lukins D, Fraser JF, Pennypacker KR., Early acid/base and electrolyte changes in permanent middle cerebral artery occlusion: Aged male and female rats, J Neurosci Res. 2020 Jan;98(1):179-190. doi: 10.1002/jnr.24422. Epub 2019 Apr 3.
    Huijgens PT, Snoeren EMS, Meisel RL, Mermelstein PG., Effects of gonadectomy and dihydrotestosterone on neuronal plasticity in motivation and reward related brain regions in the male rat, J Neuroendocrinol. 2021 Jan;33(1):e12918. doi: 10.1111/jne.12918. Epub 2020 Dec 19.
    Faunce KE, Banks ML., Effects of repeated kappa-opioid receptor agonist U-50488 treatment and subsequent termination on intracranial self-stimulation in male and female rats, Exp Clin Psychopharmacol. 2020 Feb;28(1):44-54. doi: 10.1037/pha0000287.
    Dore K, Malinow R., Elevated PSD-95 Blocks Ion-flux Independent LTD: A Potential New Role for PSD-95 in Synaptic Plasticity, Neuroscience. 2020 Feb 28:S0306-4522(20)30106-8. doi: 10.1016/j.neuroscience.2020.02.020. Online ahead of print.
    De Luca, M. A., Valentini, V., Bimpisidis, Z., Cacciapaglia, F., Caboni, P., & Di Chiara, G. (2014)., Endocannabinoid 2-arachidonoylglycerol self-administration by sprague-dawley rats and stimulation of in vivo dopamine transmission in the nucleus accumbens shell., Frontiers in Psychiatry, 5, 140. doi:10.3389/fpsyt.2014.00140 [doi]
    Bhat SA, Henry RJ, Blanchard AC, Stoica BA, Loane DJ, Faden AI., Enhanced Akt/GSK‐3β/CREB signaling mediates the anti-inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice, J Neurochem. 2020 Jan 11:e14954. doi: 10.1111/jnc.14954. Online ahead of print.
    Radford KD, Park TY, Jaiswal S, Pan H, Knutsen A, Zhang M, Driscoll M, Osborne-Smith LA, Dardzinski BJ, Choi KH., Enhanced fear memories and brain glucose metabolism (18F-FDG-PET) following sub-anesthetic intravenous ketamine infusion in Sprague-Dawley rats, Transl Psychiatry. 2018 Nov 30;8(1):263. doi: 10.1038/s41398-018-0310-8.
    Martinez LA, Gross KS, Himmler BT, Emmitt NL, Peterson BM, Zlebnik NE, Foster Olive M, Carroll ME, Meisel RL, Mermelstein PG., Estradiol Facilitation of Cocaine Self-Administration in Female Rats Requires Activation of mGluR5, eNeuro. 2016 Oct 25;3(5):ENEURO.0140-16.2016. doi: 10.1523/ENEURO.0140-16.2016. eCollection 2016 Sep-Oct.
    Robinson DL Jr, Nag S, Mokha SS., Estrogen facilitates and the kappa and mu opioid receptors mediate antinociception produced by intrathecal (-)-pentazocine in female rats, Behav Brain Res. 2016 Oct 1;312:163-8. doi: 10.1016/j.bbr.2016.06.019. Epub 2016 Jun 14.
    Dantzler HA, Kline DD., Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia, Auton Neurosci. 2020 Dec;229:102735. doi: 10.1016/j.autneu.2020.102735. Epub 2020 Sep 28.
    Ezeomah C, Cunningham KA, Stutz SJ, Fox RG, Bukreyeva N, Dineley KT, Paessler S, Cisneros IE., Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats, Brain Behav Immun. 2020 Jul;87:725-738. doi: 10.1016/j.bbi.2020.03.003. Epub 2020 Mar 9.
    Kao HW, Lin YY, Gwathney WJ, Hong K., Formulation and evaluation of multilamellar vesicles ropivacaine in pain management, Int J Nanomedicine. 2019 Sep 27;14:7891-7901. doi: 10.2147/IJN.S215952. eCollection 2019.
    Mathot F, Rbia N, Thaler R, Bishop AT, Van Wijnen AJ, Shin AY., Gene expression profiles of differentiated and undifferentiated adipose derived mesenchymal stem cells dynamically seeded onto a processed nerve allograft, Gene. 2020 Jan 15;724:144151. doi: 10.1016/j.gene.2019.144151. Epub 2019 Oct 15.
    Buckley MM, O'Brien R, Brosnan E, Ross RP, Stanton C, Buckley JM, O'Malley D., Glucagon-Like Peptide-1 Secreting L-Cells Coupled to Sensory Nerves Translate Microbial Signals to the Host Rat Nervous System, Front Cell Neurosci. 2020 Apr 30;14:95. doi: 10.3389/fncel.2020.00095. eCollection 2020.
    Joksimovic SL, Evans JG, McIntire WE, Orestes P, Barrett PQ, Jevtovic-Todorovic V, Todorovic SM., Glycosylation of Ca(V)3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes, Front Cell Neurosci. 2020 Dec 15;14:605312. doi: 10.3389/fncel.2020.605312. eCollection 2020.
    Yosten GL, Harada CM, Haddock C, Giancotti LA, Kolar GR, Patel R, Guo C, Chen Z, Zhang J, Doyle TM, Dickenson AH, Samson WK, Salvemini D., GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents, J Clin Invest. 2020 May 1;130(5):2587-2592. doi: 10.1172/JCI133270.
    Narasimhan M, Mahimainathan L, Reddy PH, Benamar K., GPR18-NAGly system in periaqueductal gray and chronic neuropathic pain, Biochim Biophys Acta Mol Basis Dis. 2020 Dec 1;1866(12):165974. doi: 10.1016/j.bbadis.2020.165974. Epub 2020 Sep 17.
    Gamdzyk M, Doycheva DM, Kang R, Tang H, Travis ZD, Tang J, Zhang JH., GW0742 activates miR-17-5p and inhibits TXNIP/NLRP3-mediated inflammation after hypoxic-ischaemic injury in rats and in PC12 cells, J Cell Mol Med. 2020 Nov;24(21):12318-12330. doi: 10.1111/jcmm.15698. Epub 2020 Oct 9.
    Rana, Sabhya; Sieck, Gary C; Mantilla, Carlos B;, Heterogeneous glutamatergic receptor mRNA expression across phrenic motor neurons in rats., Journal of neurochemistry Vol.36, 2019
    Zhang, Q. G., Wang, R. M., Scott, E., Han, D., Dong, Y., Tu, J. Y., . . . Brann, D. W. (2013)., Hypersensitivity of the hippocampal CA3 region to stress-induced neurodegeneration and amyloidogenesis in a rat model of surgical menopause, Brain : A Journal of Neurology, 136(Pt 5), 1432-1445. doi:10.1093/brain/awt046 [doi]
    Carmichael CY, Kuwabara JT, Pascale CL, Moreira JD, Mahne SE, Kapusta DR, Rosene DL, Williams JS, Cunningham JT, Wainford RD., Hypothalamic Paraventricular Nucleus GÎąi 2 (Guanine Nucleotide-Binding Protein Alpha Inhibiting Activity Polypeptide 2) Protein-Mediated Neural Control of the Kidney and the Salt Sensitivity of Blood Pressure, Hypertension. 2020 Apr;75(4):1002-1011. doi: 10.1161/HYPERTENSIONAHA.119.13777. Epub 2020 Mar 9.
    Janson J, Andersson G, Bergquist L, Eriksson M, Folgering JHA., Impact of chemical modification of sulfamidase on distribution to brain interstitial fluid and to CSF after an intravenous administration in awake, freely-moving rats, Mol Genet Metab Rep. 2019 Dec 27;22:100554. doi: 10.1016/j.ymgmr.2019.100554. eCollection 2020 Mar.
    Sirivelu, M. P., MohanKumar, P. S., & MohanKumar, S. M. (2012)., Interleukin-1 beta simultaneously affects the stress and reproductive axes by modulating norepinephrine levels in different brain areas, Life Sciences, 91(17-18), 878-884. doi:10.1016/j.lfs.2012.09.004 [doi]
    Huang J, Lu W, Doycheva DM, Gamdzyk M, Hu X, Liu R, Zhang JH, Tang J., IRE1Îą inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model, J Neuroinflammation. 2020 May 6;17(1):152. doi: 10.1186/s12974-020-01796-3.
    Comninos, A. N., Anastasovska, J., Sahuri-Arisoylu, M., Li, X., Li, S., Hu, M., . . . Dhillo, W. S. (2015)., Kisspeptin signaling in the amygdala modulates reproductive hormone secretion., Brain Structure & Function, doi:10.1007/s00429-015-1024-9 [doi]
    Gross KS, Moore KM, Meisel RL, Mermelstein PG., mGluR5 Mediates Dihydrotestosterone-Induced Nucleus Accumbens Structural Plasticity, but Not Conditioned Reward, Front Neurosci. 2018 Nov 20;12:855. doi: 10.3389/fnins.2018.00855. eCollection 2018.
    Molinet-Dronda, F., Gago, B., Quiroga-Varela, A., Juri, C., Collantes, M., Delgado, M., . . . Obeso, J. A. (2015)., Monoaminergic PET imaging and histopathological correlation in unilateral and bilateral 6-hydroxydopamine lesioned rat models of parkinson's disease: A longitudinal in-vivo study, Neurobiology of Disease, 77, 165-172. doi:10.1016/j.nbd.2015.01.007 [doi]
    Ward P, Moss HG, Brown TR, Kalivas P, Jenkins DD., N-acetylcysteine mitigates acute opioid withdrawal behaviors and CNS oxidative stress in neonatal rats, Pediatr Res. 2020 Jul;88(1):77-84. doi: 10.1038/s41390-019-0728-6. Epub 2020 Jan 14.
    Li, Y., Lein, P. J., Ford, G. D., Liu, C., Stovall, K. C., White, T. E., . . . Ford, B. D. (2015)., Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury, Journal of Neuroinflammation, 12, 64-015-0283-y. doi:10.1186/s12974-015-0283-y [doi]
    Chaudhary P, Wainford RD., Neuroanatomical characterization of G?i2-expressing neurons in the hypothalamic paraventricular nucleus of male and female Sprague-Dawley rats, Physiol Genomics. 2021 Jan 1;53(1):12-21. doi: 10.1152/physiolgenomics.00097.2020. Epub 2020 Nov 30.
    McVey Neufeld, Karen-Anne; OMahony, Siobhain M; Hoban, Alan E; Waworuntu, Rosaline V; Berg, Brian M; Dinan, Timothy G; Cryan, John F;, Neurobehavioural effects of Lactobacillus rhamnosus GG alone and in combination with prebiotics polydextrose and galactooligosaccharide in male rats exposed to early-life stress, Nutritional neuroscience Vol.22, 2019
    Belov, Oleg V; Belokopytova, Ksenia V; Kudrin, Vladimir S; Molokanov, Aleksandr G; Shtemberg, Andrey S; Bazyan, Ara S;, Neurochemical insights into the radiation protection of astronauts: Distinction between low- and moderate-LET radiation components. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology, official journal of the Italian Association of Biomedical Physics (AIFB) Vol.57, 2019
    Missault, Stephan; Anckaerts, Cynthia; Blockx, Ines; Deleye, Steven; Van Dam, Debby; Barriche, Nora; De Pauw, Glenn; Aertgeerts, Stephanie; Valkenburg, Femke; De Deyn, Peter Paul; Verhaeghe, Jeroen; Wyffels, Leonie; Van der Linden, Annemie; Staelens, Steven; Verhoye, Marleen; Dedeurwaerdere, Stefanie;, Neuroimaging of Subacute Brain Inflammation and Microstructural Changes Predicts Long-Term Functional Outcome after Experimental Traumatic Brain Injury, Journal of neurotrauma Vol.36, 2019
    Ramos-Gomez, M., Seiz, E. G., & Martinez-Serrano, A. (2015)., Optimization of the magnetic labeling of human neural stem cells and MRI visualization in the hemiparkinsonian rat brain, Journal of Nanobiotechnology, 13, 20-015-0078-4. doi:10.1186/s12951-015-0078-4 [doi]
    Choi, M., Wang, S. E., Ko, S. Y., Kang, H. J., Chae, S. Y., Lee, S. H., . . . Son, H. (2014)., Overexpression of human GATA-1 and GATA-2 interferes with spine formation and produces depressive behavior in rats., PloS One, 9(10), e109253. doi:10.1371/journal.pone.0109253 [doi]
    LaMacchia, Zach M; Spengler, Robert N; Jaffari, Muhammad; Abidi, Asif H; Ahmed, Tariq; Singh, Natasha; Tobinick, Edward L; Ignatowski, Tracey A;, Perispinal injection of a TNF blocker directed to the brain of rats alleviates the sensory and affective components of chronic constriction injury-induced neuropathic pain., Vol.82, 2019
    Puligheddu, M., Pillolla, G., Melis, M., Lecca, S., Marrosu, F., De Montis, M. G., . . . Pistis, M. (2013)., PPAR-alpha agonists as novel antiepileptic drugs: Preclinical findings., PloS One, 8(5), e64541. doi:10.1371/journal.pone.0064541 [doi]
    Melis, M., Scheggi, S., Carta, G., Madeddu, C., Lecca, S., Luchicchi, A., . . . Pistis, M. (2013)., PPARalpha regulates cholinergic-driven activity of midbrain dopamine neurons via a novel mechanism involving alpha7 nicotinic acetylcholine receptors., The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 33(14), 6203-6211. doi:10.1523/JNEUROSCI.4647-12.2013 [doi]
    Ji, Yang; Lu, Dongshuang; Wu, Limin; Qiu, Bensheng; Song, Yi-Qiao; Sun, Phillip Zhe;, Preliminary evaluation of accelerated microscopic diffusional kurtosis imaging (?DKI) in a rodent model of epilepsy., Magnetic resonance imaging Vol.56, 2019
    Frau, Roberto; Miczán, Vivien; Traccis, Francesco; Aroni, Sonia; Pongor, Csaba I; Saba, Pierluigi; Serra, Valeria; Sagheddu, Claudia; Fanni, Silvia; Congiu, Mauro; Devoto, Paola; Cheer, Joseph F; Katona, István; Melis, Miriam;, Prenatal THC exposure produces a hyperdopaminergic phenotype rescued by pregnenolone, Nature neuroscience Vol.22, 2019
    McCurdy, Ethan P; Chung, Kyung Min; Benitez-Agosto, Carlos R; Hengst, Ulrich;, Promotion of Axon Growth by the Secreted End of a Transcription Factor, Cell reports Vol.29, 2019
    Lochhead, J. J., Wolak, D. J., Pizzo, M. E., & Thorne, R. G. (2015)., Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration., Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism, 35(3), 371-381. doi:10.1038/jcbfm.2014.215 [doi]
    Barhorst KA, Alfawares Y, McGuire JL, Danzer SC, Hartings JA, Ngwenya LB., Remote and Persistent Alterations in Glutamate Receptor Subunit Composition Induced by Spreading Depolarizations in Rat Brain, Cell Mol Neurobiol. 2020 Nov 12. doi: 10.1007/s10571-020-01000-3. Online ahead of print.
    Saffari TM, Mathot F, Friedrich PF, Bishop AT, Shin AY., Revascularization patterns of nerve allografts in a rat sciatic nerve defect model, J Plast Reconstr Aesthet Surg. 2020 Mar;73(3):460-468. doi: 10.1016/j.bjps.2019.11.048. Epub 2019 Dec 11.
    Reyes, B. A., Vakharia, K., Ferraro, T. N., Levenson, R., Berrettini, W. H., & Van Bockstaele, E. J. (2012)., Reyes, B. A., Vakharia, K., Ferraro, T. N., Levenson, R., Berrettini, W. H., & Van Bockstaele, E. J. (2012). Opiate agonist-induced re-distribution of wntless, a mu-opioid receptor interacting protein, in rat striatal neurons., Experimental Neurology, 233(1), 205-213. doi:10.1016/j.expneurol.2011.09.037 [doi]
    Huynh PN, Giuvelis D, Christensen S, Tucker KL, McIntosh JM., RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats, Mar Drugs. 2019 Dec 21;18(1):12. doi: 10.3390/md18010012.
    Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Xie S, Tang J, Zuo G, Zhang JH., Rh-CSF1 attenuates neuroinflammation via the CSF1R/PLCG2/PKCÎľ pathway in a rat model of neonatal HIE, J Neuroinflammation. 2020 Jun 10;17(1):182. doi: 10.1186/s12974-020-01862-w.
    Hu X, Li S, Doycheva DM, Huang L, Lenahan C, Liu R, Huang J, Gao L, Tang J, Zuo G, Zhang JH., Rh-CSF1 Attenuates Oxidative Stress and Neuronal Apoptosis via the CSF1R/PLCG2/PKA/UCP2 Signaling Pathway in a Rat Model of Neonatal HIE, Oxid Med Cell Longev. 2020 Oct 7;2020:6801587. doi: 10.1155/2020/6801587. eCollection 2020.
    Maranon, R., Lima, R., Spradley, F. T., do Carmo, J. M., Zhang, H., Smith, A. D., . . . Reckelhoff, J. F. (2015)., Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats., American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 308(8), R708-13. doi:10.1152/ajpregu.00411.2014 [doi]
    Sauerbeck, A. D., Laws, J. L., Bandaru, V. V., Popovich, P. G., Haughey, N. J., & McTigue, D. M. (2015)., Spinal cord injury causes chronic liver pathology in rats, Journal of Neurotrauma, 32(3), 159-169. doi:10.1089/neu.2014.3497 [doi]
    Bruinstroop, E., Cano, G., Vanderhorst, V. G., Cavalcante, J. C., Wirth, J., Sena-Esteves, M., & Saper, C. B. (2012), Spinal projections of the A5, A6 (locus coeruleus), and A7 noradrenergic cell groups in rats, The Journal of Comparative Neurology, 520(9), 1985-2001. doi:10.1002/cne.23024 [doi]
    Gaidhani N, Kem WR, Uteshev VV., Spleen is not required for therapeutic effects of 4OH-GTS-21, a selective Îą7 nAChR agonist, in the sub-acute phase of ischemic stroke in rats, Brain Res. 2021 Jan 15;1751:147196. doi: 10.1016/j.brainres.2020.147196. Epub 2020 Nov 4.
    Weber, M. D., Frank, M. G., Tracey, K. J., Watkins, L. R., & Maier, S. F. (2015)., Stress induces the danger-associated molecular pattern HMGB-1 in the hippocampus of male sprague dawley rats: A priming stimulus of microglia and the NLRP3 inflammasome., The Official Journal of the Society for Neuroscience, 35(1), 316-324. doi:10.1523/JNEUROSCI.3561-14.2015 [doi]
    Hestehave S, Abelson KS, Brønnum Pedersen T, Munro G., Stress sensitivity and cutaneous sensory thresholds before and after neuropathic injury in various inbred and outbred rat strains., Behav Brain Res. 2019 Dec 16;375:112149.
    Loram, L. C., Taylor, F. R., Strand, K. A., Maier, S. F., Speake, J. D., Jordan, K. G., . . . Watkins, L. R. (2012)., Systemic administration of an alpha-7 nicotinic acetylcholine agonist reverses neuropathic pain in male sprague dawley rats., The Journal of Pain : Official Journal of the American Pain Society, 13(12), 1162-1171. doi:10.1016/j.jpain.2012.08.009 [doi]
    Worth AA, Shoop R, Tye K, Feetham CH, D'Agostino G, Dodd GT, Reimann F, Gribble FM, Beebe EC, Dunbar JD, Alexander-Chacko JT, Sindelar DK, Coskun T, Emmerson PJ, Luckman SM., The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling, Elife. 2020 Jul 29;9:e55164. doi: 10.7554/eLife.55164.
    Srinivasan, S., Simms, J. A., Nielsen, C. K., Lieske, S. P., Bito-Onon, J. J., Yi, H., . . . Bartlett, S. E. (2012)., The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration., PloS One, 7(9), e44726. doi:10.1371/journal.pone.0044726 [doi]
    Janicot R, Stafstrom CE, Shao LR., The efficacy of fructose-1,6-bisphosphate in suppressing status epilepticus in developing rats, Epilepsy Res. 2020 Dec;168:106500. doi: 10.1016/j.eplepsyres.2020.106500. Epub 2020 Nov 3.
    Schiapparelli, Lucio M; Shah, Sahil H; Ma, Yuanhui; McClatchy, Daniel B; Sharma, Pranav; Li, Jianli; Yates, John R; Goldberg, Jeffrey L; Cline, Hollis T, The Retinal Ganglion Cell Transportome Identifies Proteins Transported to Axons and Presynaptic Compartments in the Visual System In Vivo., Cell reports Vol.28, 2019
    Althaus, A. L., McCarren, H. S., Alqazzaz, A., Jackson, C., McDonough, J. H., Smith, C. D., . . . Doherty, J. J. (2017)., The synthetic neuroactive steroid SGE-516 reduces status epilepticus and neuronal cell death in a rat model of soman intoxication., Epilepsy & Behavior : E&B, 68, 22-30. doi:S1525-5050(16)30456-5 [pii]
    Moller, C., Wolf, F., van Dijk, R. M., Di Liberto, V., Russmann, V., Keck, M., . . . Potschka, H. (2018), Toward evidence-based severity assessment in rat models with repeated seizures: I. electrical kindling, Epilepsia, 59(4), 765-777. doi:10.1111/epi.14028 [doi]
    Berg EL, Pride MC, Petkova SP, Lee RD, Copping NA, Shen Y, Adhikari A, Fenton TA, Pedersen LR, Noakes LS, Nieman BJ, Lerch JP, Harris S, Born HA, Peters MM, Deng P, Cameron DL, Fink KD, Beitnere U, O'Geen H, Anderson AE, Dindot SV, Nash KR, Weeber EJ, WĂśhr M, Ellegood J, Segal DJ, Silverman JL., Translational outcomes in a full gene deletion of ubiquitin protein ligase E3A rat model of Angelman syndrome, Transl Psychiatry. 2020 Jan 27;10(1):39. doi: 10.1038/s41398-020-0720-2.
    Berg EL, Ching TM, Bruun DA, Rivera JK, Careaga M, Ellegood J, Lerch JP, WĂśhr M, Lein PJ, Silverman JL., Translational outcomes relevant to neurodevelopmental disorders following early life exposure of rats to chlorpyrifos, J Neurodev Disord. 2020 Dec 16;12(1):40. doi: 10.1186/s11689-020-09342-1.
    Yu, S. J., Grider, J. R., Gulick, M. A., Xia, C. M., Shen, S., & Qiao, L. Y. (2012)., Up-regulation of brain-derived neurotrophic factor is regulated by extracellular signal-regulated protein kinase 5 and by nerve growth factor retrograde signaling in colonic afferent neurons in colitis, Experimental Neurology, 238(2), 209-217. doi:10.1016/j.expneurol.2012.08.007 [doi]
    Bobot M, Thomas L, Moyon A, Fernandez S, McKay N, Balasse L, Garrigue P, Brige P, Chopinet S, Poitevin S, CĂŠrini C, Brunet P, Dignat-George F, Burtey S, Guillet B, Hache G., Uremic Toxic Blood-Brain Barrier Disruption Mediated by AhR Activation Leads to Cognitive Impairment during Experimental Renal Dysfunction, J Am Soc Nephrol. 2020 Jul;31(7):1509-1521. doi: 10.1681/ASN.2019070728. Epub 2020 Jun 11.
    Song, M. R., & Fellous, J. M. (2014)., Value learning and arousal in the extinction of probabilistic rewards: The role of dopamine in a modified temporal difference model, PloS One, 9(2), e89494. doi:10.1371/journal.pone.0089494 [doi]

    Nutrition

    Howick, K., Wallace-Fitzsimons, S. E., Kandil, D., Chruscicka, B., Calis, M., Murphy, E., . . . Schellekens, H. (2018)., A dairy-derived ghrelinergic hydrolysate modulates food intake in vivo., International Journal of Molecular Sciences, 19(9), 10.3390/ijms19092780. doi:E2780 [pii]
    Hohman, E. E., & Weaver, C. M. (2015)., A grape-enriched diet increases bone calcium retention and cortical bone properties in ovariectomized rats., The Journal of Nutrition, 145(2), 253-259. doi:10.3945/jn.114.198598 [doi]
    Clasen MM, Sanon TV, Hempel BJ, Nelson KH, Kearns DN, Davidson TL, Riley AL., Ad-libitum high fat diet consumption during adolescence and adulthood impacts the intravenous self-administration of cocaine in male Sprague-Dawley rats, Exp Clin Psychopharmacol. 2020 Feb;28(1):32-43. doi: 10.1037/pha0000280.
    Bondi, C. O., Taha, A. Y., Tock, J. L., Totah, N. K., Cheon, Y., Torres, G. E., . . . Moghaddam, B. (2014)., Adolescent behavior and dopamine availability are uniquely sensitive to dietary omega-3 fatty acid deficiency., Biological Psychiatry, 75(1), 38-46. doi:10.1016/j.biopsych.2013.06.007 [doi]
    Desai, B. N., & Harris, R. B. (2014), An acute method to test leptin responsiveness in rats, American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 306(11), R852-60. doi:10.1152/ajpregu.00548.2013 [doi]
    Bier A, Khasbab R, Haberman Y, Braun T, Hadar R, Sosnovski K, Amir A, Leibowitz A, Grossman E., Antibiotic Treatment Does Not Ameliorate the Metabolic Changes in Rats Presenting Dysbiosis After Consuming a High Fructose Diet, Nutrients. 2020 Jan 13;12(1):203. doi: 10.3390/nu12010203.
    Sato, H., Zhang, L. S., Martinez, K., Chang, E. B., Yang, Q., Wang, F., . . . Tso, P. (2016), Antibiotics suppress activation of intestinal mucosal mast cells and reduce dietary lipid absorption in sprague-dawley rats., Gastroenterology, 151(5), 923-932. doi:S0016-5085(16)34786-2 [pii]
    Komnenov D, Levanovich PE, Perecki N, Chung CS, Rossi NF., Aortic Stiffness and Diastolic Dysfunction in Sprague Dawley Rats Consuming Short-Term Fructose Plus High Salt Diet, Integr Blood Press Control. 2020 Sep 28;13:111-124. doi: 10.2147/IBPC.S257205. eCollection 2020.
    Zhang, L. S., Sato, H., Yang, Q., Ryan, R. O., Wang, D. Q., Howles, P. N., & Tso, P. (2015)., Apolipoprotein A-V is present in bile and its secretion increases with lipid absorption in sprague-dawley rats, American Journal of Physiology.Gastrointestinal and Liver Physiology, 309(11), G918-25. doi:10.1152/ajpgi.00227.2015 [doi]
    Park, C. Y., Lee, W. H., Fleet, J. C., Allen, M. R., McCabe, G. P., Walsh, D. M., & Weaver, C. M. (2014)., Calcium and vitamin D intake maintained from preovariectomy independently affect calcium metabolism and bone properties in sprague dawley rats., Osteoporosis International : A Journal Established as Result of Cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 25(7), 1905-1915. doi:10.1007/s00198-014-2709-2 [doi]
    Harris RBS., Consuming sucrose solution promotes leptin resistance and site specifically modifies hypothalamic leptin signaling in rats, Am J Physiol Regul Integr Comp Physiol. 2020 Nov 18. doi: 10.1152/ajpregu.00238.2020. Online ahead of print.
    Minaya DM, Turlej A, Joshi A, Nagy T, Weinstein N, DiLorenzo P, Hajnal A, Czaja K., Consumption of a high energy density diet triggers microbiota dysbiosis, hepatic lipidosis, and microglia activation in the nucleus of the solitary tract in rats, Nutr Diabetes. 2020 Jun 9;10(1):20. doi: 10.1038/s41387-020-0119-4.
    Ari, Csilla; Koutnik, Andrew P; DeBlasi, Janine; Landon, Carol; Rogers, Christopher Q; Vallas, John; Bharwani, Sahil; Puchowicz, Michelle; Bederman, Ilya; Diamond, David M; Kindy, Mark S; Dean, Jay B; D Agostino, Dominic P;, Delaying latency to hyperbaric oxygen-induced CNS oxygen toxicity seizures by combinations of exogenous ketone supplements., Physiological reports Vol.7, 2019
    Rehder Silinski MA, Gilliam JA, Fernando RA, Robinson VG, Germolec D, Cunny H, Huang MC, Furr J, Waidyanatha S., Development of an Analytical Method for Quantitation of Deoxynivalenol by UPLC-MS-MS: a Preliminary Assessment of Gestational and Lactational Transfer in Rats, J Anal Toxicol. 2020 Sep 4:bkaa119. doi: 10.1093/jat/bkaa119. Online ahead of print.
    Bello, N. T., Coughlin, J. W., Redgrave, G. W., Ladenheim, E. E., Moran, T. H., & Guarda, A. S. (2012)., Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density., Physiology & Behavior, 105(3), 720-726. doi:10.1016/j.physbeh.2011.09.021 [doi]
    Smazal, A. L., Borcherding, N. C., Anderegg, A. S., Schalinske, K. L., Whitley, E. M., & Rowling, M. J. (2013)., Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats., The Journal of Nutrition, 143(7), 1123-1128. doi:10.3945/jn.112.173278 [doi]
    Guice J, Bendiks ZA, Coulon D, Raggio AM, Page RC, Carvajal-Aldaz DG, Lou M, Welsh DA, Marx BD, Taylor CM, Husseneder C, Marco ML, Keenan MJ., Differences in Capacity of High-Amylose Resistant Starch, Whole-Grain Flour, and a Combination of Both to Modify Intestinal Responses of Male Sprague Dawley Rats Fed Moderate and High Fat Diets, J Agric Food Chem. 2020 Dec 23;68(51):15176-15185. doi: 10.1021/acs.jafc.0c05285. Epub 2020 Dec 8.
    Larsen AT, Sonne N, Andreassen KV, Karsdal MA, Henriksen K., Dose Frequency Optimization of the Dual Amylin and Calcitonin Receptor Agonist KBP-088: Long-Lasting Improvement in Food Preference and Body Weight Loss, J Pharmacol Exp Ther. 2020 May;373(2):269-278. doi: 10.1124/jpet.119.263400. Epub 2020 Feb 18.
    Lee TJ, Hargrave SL, Kinzig KP., Dual functions of CNS inflammation in food intake and metabolic regulation, Brain Res. 2020 Aug 1;1740:146859. doi: 10.1016/j.brainres.2020.146859. Epub 2020 Apr 27.
    Davidson, E. P., Coppey, L. J., Shevalye, H., Obrosov, A., & Yorek, M. A. (2018), Effect of dietary content of menhaden oil with or without salsalate on neuropathic endpoints in high-fat-Fed/Low-dose streptozotocin-treated sprague dawley rats, Journal of Diabetes Research, 2018, 2967127. doi:10.1155/2018/2967127 [doi]
    Velázquez AM, Roglans N, Bentanachs R, Gené M, Sala-Vila A, Lázaro I, Rodríguez-Morató J, Sánchez RM, Laguna JC, Alegret M., Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation, Nutrients. 2020 Oct 23;12(11):3240. doi: 10.3390/nu12113240.
    Kesl, S. L., Poff, A. M., Ward, N. P., Fiorelli, T. N., Ari, C., Van Putten, A. J., . . . D'Agostino, D. P. (2016)., Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in sprague-dawley rats, Nutrition & Metabolism, 13, 9-016-0069-y. eCollection 2016. doi:10.1186/s12986-016-0069-y [doi]
    Brinkman, A. S., Murali, S. G., Hitt, S., Solverson, P. M., Holst, J. J., & Ney, D. M. (2012)., Enteral nutrients potentiate glucagon-like peptide-2 action and reduce dependence on parenteral nutrition in a rat model of human intestinal failure, American Journal of Physiology.Gastrointestinal and Liver Physiology, 303(5), G610-22. doi:10.1152/ajpgi.00184.2012 [doi]
    Aslam, F., Iqbal, S., Nasir, M., Anjum, A. A., Swan, P., & Sweazea, K. (2017)., Evaluation of white sesame seed oil on glucose control and biomarkers of hepatic, cardiac, and renal functions in male sprague-dawley rats with chemically induced diabetes., Journal of Medicinal Food, 20(5), 448-457. doi:10.1089/jmf.2016.0065 [doi]
    Volcko KL, Brakey DJ, Przybysz JT, Daniels D., Exclusively drinking sucrose or saline early in life alters adult drinking behavior by laboratory rats, Appetite. 2020 Jun 1;149:104616. doi: 10.1016/j.appet.2020.104616. Epub 2020 Feb 4.
    Nguyen, V. A., Le, T., Tong, M., Mellion, M., Gilchrist, J., & de la Monte, S. M. (2012)., Experimental alcohol-related peripheral neuropathy: Role of insulin/IGF resistance., Nutrients, 4(8), 1042-1057. doi:10.3390/nu4081042 [doi]
    Pierce-Messick Z, Pratt WE., Glucagon-like peptide-1 receptors modulate the binge-like feeding induced by Âľ-opioid receptor stimulation of the nucleus accumbens in the rat, Neuroreport. 2020 Dec 16;31(18):1283-1288. doi: 10.1097/WNR.0000000000001545.
    Buczek L, Migliaccio J, Petrovich GD., Hedonic Eating: Sex Differences and Characterization of Orexin Activation and Signaling, Neuroscience. 2020 Jun 1;436:34-45. doi: 10.1016/j.neuroscience.2020.04.008. Epub 2020 Apr 10.
    Cox, G. N., Chlipala, E. A., Smith, D. J., Carlson, S. J., Bell, S. J., & Doherty, D. H. (2014)., Hematopoietic properties of granulocyte colony-stimulating factor/immunoglobulin (G-CSF/IgG-fc) fusion proteins in normal and neutropenic rodents, PloS One, 9(3), e91990. doi:10.1371/journal.pone.0091990 [doi]
    Marks, K. A., Kitson, A. P., & Stark, K. D. (2013), Hepatic and plasma sex differences in saturated and monounsaturated fatty acids are associated with differences in expression of elongase 6, but not stearoyl-CoA desaturase in sprague-dawley rats., Genes & Nutrition, 8(3), 317-327. doi:10.1007/s12263-012-0325-3 [doi]
    Volcko KL, Carroll QE, Brakey DJ, Daniels D., High-fat diet alters fluid intake without reducing sensitivity to glucagon-like peptide-1 receptor agonist effects, Physiol Behav. 2020 Jul 1;221:112910. doi: 10.1016/j.physbeh.2020.112910. Epub 2020 Apr 10.
    Bello, N. T., Walters, A. L., Verpeut, J. L., & Cunha, P. P. (2013), High-fat diet-induced alterations in the feeding suppression of low-dose nisoxetine, a selective norepinephrine reuptake inhibitor., Journal of Obesity, 2013, 457047. doi:10.1155/2013/457047 [doi]
    Cladis DP, Debelo H, Lachcik PJ, Ferruzzi MG, Weaver CM., Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats, Mol Nutr Food Res. 2020 Jun;64(12):e2000031. doi: 10.1002/mnfr.202000031. Epub 2020 May 27.
    Egerton S, Donoso F, Fitzgerald P, Gite S, Fouhy F, Whooley J, Dinan TG, Cryan JF, Culloty SC, Ross RP, Stanton C., Investigating the potential of fish oil as a nutraceutical in an animal model of early life stress, Nutr Neurosci. 2020 Jul 31:1-23. doi: 10.1080/1028415X.2020.1753322. Online ahead of print.
    Tapani, S., Almquist, J., Leander, J., Ahlstrom, C., Peletier, L. A., Jirstrand, M., & Gabrielsson, J. (2014)., Joint feedback analysis modeling of nonesterified fatty acids in obese zucker rats and normal sprague-dawley rats after different routes of administration of nicotinic acid., Journal of Pharmaceutical Sciences, 103(8), 2571-2584. doi:10.1002/jps.24077 [doi]
    Mabasa, L., Cho, K., Walters, M. W., Bae, S., & Park, C. S. (2013), Maternal dietary canola oil suppresses growth of mammary carcinogenesis in female rat offspring., Nutrition and Cancer, 65(5), 695-701. doi:10.1080/01635581.2013.789539 [doi]
    Stewart, L K; Smoak, P; Hydock, D S; Hayward, R; OBrien, K; Lisano, J K; Boeneke, C; Christensen, M; Mathias, A;, Milk and kefir maintain aspects of health during doxorubicin treatment in rats., Journal of dairy science Vol.102, 2019
    Aigbologa J, Connolly M, Buckley JM, O'Malley D., Mucosal Tuft Cell Density Is Increased in Diarrhea-Predominant Irritable Bowel Syndrome Colonic Biopsies, Front Psychiatry. 2020 May 15;11:436. doi: 10.3389/fpsyt.2020.00436. eCollection 2020.
    Coulon DB, Page R, Raggio AM, Guice J, Marx B, Gourineni V, Stewart ML, Keenan MJ., Novel Resistant Starch Type 4 Products of Different Starch Origins, Production Methods, and Amounts Are Not Equally Fermented when Fed to Sprague-Dawley Rats, Mol Nutr Food Res. 2020 Jan;64(2):e1900901. doi: 10.1002/mnfr.201900901. Epub 2019 Dec 23.
    Goodrich, K. M., Smithson, A. T., Ickes, A. K., & Neilson, A. P. (2015)., Pan-colonic pharmacokinetics of catechins and procyanidins in male sprague-dawley rats., The Journal of Nutritional Biochemistry, doi:S0955-2863(15)00107-2 [pii]
    Pawlowski, J. W., Martin, B. R., McCabe, G. P., Ferruzzi, M. G., & Weaver, C. M. (2014)., Plum and soy aglycon extracts superior at increasing bone calcium retention in ovariectomized sprague dawley rats., Journal of Agricultural and Food Chemistry, 62(26), 6108-6117. doi:10.1021/jf403310q [doi]
    Knapp, B. K., Bauer, L. L., Swanson, K. S., Tappenden, K. A., Fahey, G. C.,Jr, & de Godoy, M. R. (2013)., Soluble fiber dextrin and soluble corn fiber supplementation modify indices of health in cecum and colon of sprague-dawley rats, Nutrients, 5(2), 396-410. doi:10.3390/nu5020396 [doi]
    Chen, J. R., Lazarenko, O. P., Blackburn, M. L., Badger, T. M., & Ronis, M. J. (2015)., Soy protein isolate inhibits high-fat diet-induced senescence pathways in osteoblasts to maintain bone acquisition in male rats., Endocrinology, 156(2), 475-487. doi:10.1210/en.2014-1427 [doi]
    Arman T, Lynch KD, Goedken M, Clarke JD., Sub-chronic microcystin-LR renal toxicity in rats fed a high fat/high cholesterol diet, Chemosphere. 2020 Oct 27:128773. doi: 10.1016/j.chemosphere.2020.128773. Online ahead of print.
    Grebenstein, P. E., Harp, J. L., & Rowland, N. E. (2013)., The effects of noncontingent and self-administered cytisine on body weight and meal patterns in male sprague-dawley rats., Pharmacology, Biochemistry, and Behavior, 110, 192-200. doi:10.1016/j.pbb.2013.07.012 [doi]
    Vaziri, N. D., Liu, S. M., Lau, W. L., Khazaeli, M., Nazertehrani, S., Farzaneh, S. H., . . . Martin, R. J. (2014), Value learning and arousal in the extinction of probabilistic rewards: The role of dopamine in a modified temporal difference model, PloS One, 9(12), e114881. doi:10.1371/journal.pone.0114881 [doi]
    Hong, M. Y., Hartig, N., Kaufman, K., Hooshmand, S., Figueroa, A., & Kern, M. (2015)., Watermelon consumption improves inflammation and antioxidant capacity in rats fed an atherogenic diet., Nutrition Research (New York, N.Y.), 35(3), 251-258. doi:10.1016/j.nutres.2014.12.005 [doi]
    Moody, L., Liang, J., Choi, P. P., Moran, T. H., & Liang, N. C. (2015), Wheel running decreases palatable diet preference in sprague-dawley rats, Physiology & Behavior, 150, 53-63. doi:10.1016/j.physbeh.2015.03.019 [doi]
    Moody, L., Liang, J., Choi, P. P., Moran, T. H., & Liang, N. C. (2015), Wheel running decreases palatable diet preference in sprague-dawley rats., Physiology & Behavior, 150, 53-63. doi:10.1016/j.physbeh.2015.03.019 [doi]
    Levanovich PE, Chung CS, Komnenov D, Rossi NF., Fructose plus High-Salt Diet in Early Life Results in Salt-Sensitive Cardiovascular Changes in Mature Male Sprague Dawley Rats, Nutrients. 2021 Sep 8;13(9):3129. doi: 10.3390/nu13093129.
    Lackey KA, Fleming SA., Brief Research Report: Estimation of the Protein Digestibility-Corrected Amino Acid Score of Defatted Walnuts, Front Nutr. 2021 Sep 6;8:702857. doi: 10.3389/fnut.2021.702857. eCollection 2021.
    Turner RT, Wong CP, Fosse KM, Branscum AJ, Iwaniec UT., Caloric Restriction and Hypothalamic Leptin Gene Therapy Have Differential Effects on Energy Partitioning in Adult Female Rats, Int J Mol Sci. 2021 Jun 24;22(13):6789. doi: 10.3390/ijms22136789.
    DiSilvestro RA, Dardenne M, Joseph E., Comparison of Thymulin Activity with Other Measures of Marginal Zinc Deficiency, Biol Trace Elem Res. 2021 Feb;199(2):585-587. doi: 10.1007/s12011-020-02159-y. Epub 2020 May 3.
    Garcia J, Mankin P, Gnanamony M, de Alarcon PA., Evaluation of angiogenic signaling molecules associated with reactive thrombocytosis in an iron-deficient rat model, Pediatr Res. 2021 Aug;90(2):341-346. doi: 10.1038/s41390-020-01318-0. Epub 2021 Jan 19.
    Jobgen WS, Lee MJ, Fried SK, Wu G., l-Arginine supplementation regulates energy-substrate metabolism in skeletal muscle and adipose tissue of diet-induced obese rats, Exp Biol Med (Maywood). 2022 Dec 21:15353702221139207. doi: 10.1177/15353702221139207. Online ahead of print.
    Redondo-Calvo FJ, Bejarano-Ramírez N, Baladrón V, Montenegro O, Gómez LA, Velasco R, Villasanti N, Illescas S, Franco-Sereno MT, Gracia I, Rodríguez JF, Muñoz-Rodríguez JR, Pérez-Ortiz JM., Black Garlic and Thiosulfinate-Enriched Extracts as Adjuvants to Ceftriaxone Treatment in a Rat Peritonitis Model of Sepsis, Biomedicines. 2022 Dec 1;10(12):3095. doi: 10.3390/biomedicines10123095.
    Jobgen WS, Wu G., Dietary L-arginine supplementation increases the hepatic expression of AMP-activated protein kinase in rats, Amino Acids. 2022 Dec;54(12):1569-1584. doi: 10.1007/s00726-022-03194-w. Epub 2022 Aug 16.
    Ramos-Romero S, Ponomarenko J, Amézqueta S, Hereu M, Miralles-Pérez B, Romeu M, Méndez L, Medina I, Torres JL., Fiber-like Action of d-Fagomine on the Gut Microbiota and Body Weight of Healthy Rats, Nutrients. 2022 Nov 3;14(21):4656. doi: 10.3390/nu14214656.
    Wang R, Santos JM, Dufour JM, Stephens ER, Miranda JM, Washburn RL, Hibler T, Kaur G, Lin D, Shen CL., Ginger Root Extract Improves GI Health in Diabetic Rats by Improving Intestinal Integrity and Mitochondrial Function, Nutrients. 2022 Oct 19;14(20):4384. doi: 10.3390/nu14204384.
    Levanovich PE, Daugherty AM, Komnenov D, Rossi NF., Dietary fructose and high salt in young male Sprague Dawley rats induces salt-sensitive changes in renal function in later life, Physiol Rep. 2022 Sep;10(18):e15456. doi: 10.14814/phy2.15456.
    Ahn W, Latremouille J, Harris RBS., Leptin receptor-expressing cells in the ventromedial nucleus of the hypothalamus contribute to enhanced CCK-induced satiety following central leptin injection, Am J Physiol Endocrinol Metab. 2022 Sep 1;323(3):E267-E280. doi: 10.1152/ajpendo.00088.2022. Epub 2022 Jul 13.
    He Y, Qu J, Yang Q, Wu Z, Liu M, Tso P., Effect of L-Glutamine on Chylomicron Formation and Fat-Induced Activation of Intestinal Mucosal Mast Cells in Sprague-Dawley Rats, Nutrients. 2022 Apr 24;14(9):1777. doi: 10.3390/nu14091777.
    Alawadi AA, Benedito VA, Skinner RC, Warren DC, Showman C, Tou JC., RNA-sequencing revealed apple pomace ameliorates expression of genes in the hypothalamus associated with neurodegeneration in female rats fed a Western diet during adolescence to adulthood, Nutr Neurosci. 2022 Mar 17:1-13. doi: 10.1080/1028415X.2022.2050008. Online ahead of print.
    Maunze B, Bruckner KW, Desai NN, Chen C, Chen F, Baker D, Choi S., Pituitary adenylate cyclase-activating polypeptide receptor activation in the hypothalamus recruits unique signaling pathways involved in energy homeostasis, Am J Physiol Endocrinol Metab. 2022 Mar 1;322(3):E199-E210. doi: 10.1152/ajpendo.00320.2021. Epub 2022 Jan 10.

    Oncology

    Guinn, Z., Brown, D. M., & Petro, T. M. (2017)., Activation of IRF3 contributes to IFN-gamma and ISG54 expression during the immune responses to B16F10 tumor growth, International Immunopharmacology, 50, 121-129. doi:S1567-5769(17)30238-2 [pii]
    Assimon VA, Tang Y, Vargas JD, Lee GJ, Wu ZY, Lou K, Yao B, Menon MK, Pios A, Perez KC, Madriaga A, Buchowiecki PK, Rolfe M, Shawver L, Jiao X, Le Moigne R, Zhou HJ, Anderson DJ., CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity, ACS Chem Biol. 2019 Feb 15;14(2):236-244
    Forsgard, R. A., Marrachelli, V. G., Korpela, K., Frias, R., Collado, M. C., Korpela, R., . . . Osterlund, P. (2017), Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male sprague-dawley rats., Cancer Chemotherapy and Pharmacology, 80(2), 317-332. doi:10.1007/s00280-017-3364-z [doi]
    Lyski RD, Bou LB, Lau UY, Meyer DW, Cochran JH, Okeley NM, Emmerton KK, Zapata F, Simmons JK, Trueblood ES, Ortiz DJ, Zaval MC, Snead KM, Jin S, Farr LM, Ryan MC, Senter PD, Jeffrey SC., Development of Novel Antibody-Camptothecin Conjugates, Mol Cancer Ther. 2020 Dec 3:molcanther.0526.2020. doi: 10.1158/1535-7163.MCT-20-0526. Online ahead of print.
    Khazal, K. F., Samuel, T., Hill, D. L., & Grubbs, C. J. (2013)., Effect of an extract of withania somnifera root on estrogen receptor-positive mammary carcinomas., Anticancer Research, 33(4), 1519-1523. doi:33/4/1519 [pii]
    Eskra, Jillian N; Dodge, Alaina; Schlicht, Michael J; Bosland, Maarten C;, Effects of Black Raspberries and Their Constituents on Rat Prostate Carcinogenesis and Human Prostate Cancer Cell Growth In Vitro., Nutrition and cancer Vol.48, 2019
    Dennison, K. L., Chack, A. C., Hickman, M. P., Harenda, Q. E., & Shull, J. D. (2018), Ept7, a quantitative trait locus that controls estrogen-induced pituitary lactotroph hyperplasia in rat, is orthologous to a locus in humans that has been associated with numerous cancer types and common diseases., PloS One, 13(9), e0204727. doi:10.1371/journal.pone.0204727 [doi]
    Griffiths, L. A., Duggett, N. A., Pitcher, A. L., & Flatters, S. J. L. (2018), Evoked and ongoing pain-like behaviours in a rat model of paclitaxel-induced peripheral neuropathy, Pain Research & Management, 2018, 8217613. doi:10.1155/2018/8217613 [doi]
    Allen, J. E., Crowder, R. N., & El-Deiry, W. S. (2015)., First-in-class small molecule ONC201 induces DR5 and cell death in tumor but not normal cells to provide a wide therapeutic index as an anti-cancer agent., PloS One, 10(11), e0143082. doi:10.1371/journal.pone.0143082 [doi]
    Wong, R. L., Wang, Q., Trevino, L. S., Bosland, M. C., Chen, J., Medvedovic, M., . . . Walker, C. L. (2015)., Identification of secretaglobin Scgb2a1 as a target for developmental reprogramming by BPA in the rat prostate., Epigenetics, 10(2), 127-134. doi:10.1080/15592294.2015.1009768 [doi]
    Pi, C., Allott, E. H., Ren, D., Poulton, S., Lee, S. Y., Perkins, S., . . . Parker, W. (2015)., Increased biodiversity in the environment improves the humoral response of rats, PloS One, 10(4), e0120255. doi:10.1371/journal.pone.0120255 [doi]
    Shiota, M., Bishop, J. L., Takeuchi, A., Nip, K. M., Cordonnier, T., Beraldi, E., . . . Zoubeidi, A. (2015)., Inhibition of the HER2-YB1-AR axis with lapatinib synergistically enhances enzalutamide anti-tumor efficacy in castration resistant prostate cancer., Oncotarget, 6(11), 9086-9098. doi:3602 [pii]
    Sgarra, L., Leo, V., Addabbo, F., Iacobazzi, D., Carratu, M. R., Montagnani, M., & Potenza, M. A. (2014)., Intermittent losartan administration triggers cardiac post-conditioning in isolated rat hearts: Role of BK2 receptors., PloS One, 9(2), e88542. doi:10.1371/journal.pone.0088542 [doi]
    Forsgard, R. A., Korpela, R., Holma, R., Linden, J., Frias, R., Spillmann, T., & Osterlund, P. (2016), Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in sprague-dawley rats., Cancer Chemotherapy and Pharmacology, 78(4), 863-874. doi:10.1007/s00280-016-3150-3 [doi]
    Thompson, M. D., Grubbs, C. J., Bode, A. M., Reid, J. M., McGovern, R., Bernard, P. S., . . . Lubet, R. A. (2015)., Lack of effect of metformin on mammary carcinogenesis in nondiabetic rat and mouse models., Cancer Prevention Research (Philadelphia, Pa.), 8(3), 231-239. doi:10.1158/1940-6207.CAPR-14-0181-T [doi]
    Zaidi, A. H., Saldin, L. T., Kelly, L. A., Bergal, L., Londono, R., Kosovec, J. E., . . . Jobe, B. A. (2015)., MicroRNA signature characterizes primary tumors that metastasize in an esophageal adenocarcinoma rat model., PloS One, 10(3), e0122375. doi:10.1371/journal.pone.0122375 [doi]
    England, C. G., Ehlerding, E. B., Hernandez, R., Rekoske, B. T., Graves, S. A., Sun, H., . . . Cai, W. (2017)., Preclinical pharmacokinetics and biodistribution studies of 89Zr-labeled pembrolizumab., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 58(1), 162-168. doi:10.2967/jnumed.116.177857 [doi]
    ThyagaRajan, S., Tran, L., Molinaro, C. A., Gridley, D. S., Felten, D. L., & Bellinger, D. L. (2013), Prevention of mammary tumor development through neuroimmunomodulation in the spleen and lymph nodes of old female sprague-dawley rats by L-deprenyl., Neuroimmunomodulation, 20(3), 141-151. doi:10.1159/000346200 [doi]
    He Y, Hwang DJ, Ponnusamy S, Thiyagarajan T, Mohler ML, Narayanan R, Miller DD., Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer, J Med Chem. 2020 Nov 12;63(21):12642-12665. doi: 10.1021/acs.jmedchem.0c00943. Epub 2020 Oct 23.
    Neumann, C. S., Olivas, K. C., Anderson, M. E., Cochran, J. H., Jin, S., Li, F., . . . Senter, P. D. (2018)., Targeted delivery of cytotoxic NAMPT inhibitors using antibody-drug conjugates., Molecular Cancer Therapeutics, doi:molcanther.0643.2018 [pii]
    Carroll, C. E., Liang, Y., Benakanakere, I., Besch-Williford, C., & Hyder, S. M. (2013)., The anticancer agent YC-1 suppresses progestin-stimulated VEGF in breast cancer cells and arrests breast tumor development., International Journal of Oncology, 42(1), 179-187. doi:10.3892/ijo.2012.1675 [doi]
    De La Chapa JJ, Singha PK, Self KK, Sallaway ML, McHardy SF, Hart MJ, McGuff HS, Valdez MC, Ruiz F 2nd, Polusani SR, Gonzales CB, The novel capsazepine analog, CIDD-99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1-independent induction of ER stress, mitochondrial dysfunction, and apoptosis., J Oral Pathol Med. 2019 May;48(5):389-399.
    Forsgård, Richard A; Marrachelli, Vannina G; Lindén, Jere; Frias, Rafael; Collado, Maria Carmen; Korpela, Riitta; Monleon, Daniel; Spillmann, Thomas; Österlund, Pia, Two-Week Aflibercept or Erlotinib Administration Does Not Induce Changes in Intestinal Morphology in Male Sprague-Dawley Rats But Aflibercept Affects Serum and Urine Metabolic Profiles., Translational oncology Vol.12, 2019
    Sharp AM, Lertphinyowong S, Yee SS, Paredes D, Gelfond J, Johnson-Pais TL, Leach RJ, Liss M, Risinger AL, Sullivan AC, Thompson IM, Morilak DA., Vortioxetine reverses medial prefrontal cortex-mediated cognitive deficits in male rats induced by castration as a model of androgen deprivation therapy for prostate cancer, Psychopharmacology (Berl). 2019 Nov;236(11):3183-3195. doi: 10.1007/s00213-019-05274-4. Epub 2019 May 28.
    Ibrahim R, Brix A, Malarkey DE, Nyska A, Asif M, Ramot Y., Chemical-Induced Oral Squamous Cell Neoplasms in Rodents: An Overview of NTP 2-Year Cancer Studies, Toxicol Pathol. 2021 Jul;49(5):1062-1076. doi: 10.1177/0192623321989956. Epub 2021 Feb 12.
    Pettinato AM, Yoo D, VanOudenhove J, Chen YS, Cohn R, Ladha FA, Yang X, Thakar K, Romano R, Legere N, Meredith E, Robson P, Regnier M, Cotney JL, Murry CE, Hinson JT., Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment, Cell Rep. 2021 May 4;35(5):109088. doi: 10.1016/j.celrep.2021.109088.
    Nehra G, Andrews S, Rettig J, Gould MN, Haag JD, Howard SP, Thorne RG., Intranasal administration of the chemotherapeutic perillyl alcohol results in selective delivery to the cerebrospinal fluid in rats, Sci Rep. 2021 Mar 18;11(1):6351. doi: 10.1038/s41598-021-85293-4.
    Moquist PN, Bovee TD, Waight AB, Mitchell JA, Miyamoto JB, Mason ML, Emmerton KK, Stevens N, Balasubramanian C, Simmons JK, Lyon RP, Senter PD, Doronina SO., Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models, Mol Cancer Ther. 2021 Feb;20(2):320-328. doi: 10.1158/1535-7163.MCT-20-0618. Epub 2020 Dec 7.
    Kumar A, Lubet RA, Fox JT, Nelson WG, Seifried H, Grubbs CJ, Miller MS., Effects of High-Fructose Diet vs. Teklad Diet in the MNU-Induced Rat Mammary Cancer Model: Altered Tumorigenesis, Metabolomics and Tumor RNA Expression, J Obes Chronic Dis. 2021;5(1):67-78. Epub 2021 Jan 11.
    Nash AM, Aghlara-Fotovat S, Castillio B, Hernandez A, Pugazenthi A, Lee HS, Jang HJ, Nguyen A, Lu A, Burt BM, Ghanta RK, Veiseh O., Activation of Adaptive and Innate Immune Cells via Localized IL2 Cytokine Factories Eradicates Mesothelioma Tumors, Clin Cancer Res. 2022 Dec 1;28(23):5121-5135. doi: 10.1158/1078-0432.CCR-22-1493.
    Liu X, Li Q, Wang Y, Crawford M, Bhupal PK, Gao X, Xie H, Liang D, Cheng YL, Liu X, Tsai RYL., Designing a Mucoadhesive ChemoPatch to Ablate Oral Dysplasia for Cancer Prevention, Small. 2022 Jun;18(25):e2201561. doi: 10.1002/smll.202201561. Epub 2022 May 19.
    Murdock MH, Hussey GS, Chang JT, Hill RC, Nascari DG, Rao AV, Hansen KC, Foley LM, Hitchens TK, Amankulor NM, Badylak SF., A liquid fraction of extracellular matrix inhibits glioma cell viability in vitro and in vivo, Oncotarget. 2022 Feb 21;13:426-438. doi: 10.18632/oncotarget.28203. eCollection 2022.

    Preclincial (PK/PD)

    Katyayan KK, Hui YH., An evaluation of metabolite profiling of six drugs using dried blood spot, Xenobiotica. 2019 Dec;49(12):1458-1469. doi: 10.1080/00498254.2019.1572938. Epub 2019 Feb 18.
    Rioux N, Smith S, Korpal M, O'Shea M, Prajapati S, Zheng GZ, Warmuth M, Smith PG., Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERÎą covalent antagonist (SERCA), Cancer Chemother Pharmacol. 2019 Jan;83(1):151-160. doi: 10.1007/s00280-018-3716-3. Epub 2018 Nov 1.
    Grecco GG, Kisor DF, Sprague JE., Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats, Data Brief. 2018 Oct 25;21:1045-1050. doi: 10.1016/j.dib.2018.10.073. eCollection 2018 Dec.
    Sarkar M, Grossman RG, Toups EG, Chow DS., Rational design and development of a stable liquid formulation of riluzole and its pharmacokinetic evaluation after oral and IV administrations in rats, Eur J Pharm Sci. 2018 Dec 1;125:1-10. doi: 10.1016/j.ejps.2018.09.004. Epub 2018 Sep 8.
    Kim YJ, Tu Y, Chow DS., Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats, J Pharm Biomed Anal. 2018 Nov 30;161:122-128. doi: 10.1016/j.jpba.2018.07.058. Epub 2018 Aug 2.
    Crowley ML, Restrepo LF, Gamez-Jimenez LR, Patel A, Braun T, Pallares VLC, Ho NP, Reeves ME, McCurdy CR, McMahon LR, Hiranita T., The use of hypercapnic conditions to assess opioid-induced respiratory depression in rats., J Pharmacol Toxicol Methods. 2021 Sep-Oct;111:107101. doi: 10.1016/j.vascn.2021.107101. Epub 2021 Jul 7.
    Berthold EC, Kamble SH, Raju KS, King TI, Popa R, Sharma A, León F, Avery BA, McMahon LR, McCurdy CR., Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method., J Pharm Biomed Anal. 2021 Feb 5;194:113778. doi: 10.1016/j.jpba.2020.113778. Epub 2020 Nov 21.
    Sharma PK, Kushwaha A, Repka MA, Murthy SN, Formulation development and pharmacokinetic investigation of self-assembled hybrid niosomes for oral delivery of 17-Hydroxyprogesterone caproate, Journal of Drug Delivery Science and Technology Volume 61, February 2021, 102215
    Ahmed F, Rahman Md, Thompson R, Bereiter DA., Role of Connexin 43 in an Inflammatory Model for TMJ Hyperalgesia, Front. Pain Res., 03 August 2021.

    Reproductive

    Deepika Kubsad, Eric E Nilsson, Stephanie E King, Ingrid Sadler-Riggleman, Daniel Beck, Michael K Skinner, Assessment of Glyphosate Induced Epigenetic Transgenerational Inheritance of Pathologies and Sperm Epimutations: Generational Toxicology, Sci Rep. 2019 Apr 23;9(1):6372. doi: 10.1038/s41598-019-42860-0.
    Lovelock DF, Deak T., Acute stress imposed during adolescence has minimal effects on hypothalamic-pituitary-adrenal (HPA) axis sensitivity in adulthood in female Sprague Dawley rats, Physiol Behav. 2020 Jan 1;213:112707. doi: 10.1016/j.physbeh.2019.112707. Epub 2019 Oct 18.
    Deer E, Reeve KE, Amaral L, Vaka VR, Franks M, Campbell N, Fitzgerald S, Herrock O, Ibrahim T, Cornelius D, LaMarca B., CD4+ T cells cause renal and placental mitochondrial oxidative stress as mechanisms of hypertension in response to placental ischemia, Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F47-F54. doi: 10.1152/ajprenal.00398.2020. Epub 2020 Nov 16.
    Palei, A. C., Spradley, F. T., & Granger, J. P. (2015)., Chronic hyperleptinemia results in the development of hypertension in pregnant rats. American, American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 308(10), R855-61. doi:10.1152/ajpregu.00286.2014 [doi]
    Ding, Lina; Shunkwiler, Lauren B; Harper, Nicholas W; Zhao, Yang; Hinohara, Kunihiko; Huh, Sung Jin; Ekram, Muhammad B; Guz, Jan; Kern, Michael J; Awgulewitsch, Alexander; Shull, James D; Smits, Bart M G; Polyak, Kornelia, Deletion of Cdkn1b in ACI rats leads to increased proliferation and pregnancy-associated changes in the mammary gland due to perturbed systemic endocrine environment, PLoS genetics Vol.15, 2019
    Ben Maamar, Millissia; Nilsson, Eric; Sadler-Riggleman, Ingrid; Beck, Daniel; McCarrey, John R; Skinner, Michael K;, Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure., Developmental biology Vol.445, 2019
    Walker, D. M., Kermath, B. A., Woller, M. J., & Gore, A. C. (2013)., Disruption of reproductive aging in female and male rats by gestational exposure to estrogenic endocrine disruptors., Endocrinology, 154(6), 2129-2143. doi:10.1210/en.2012-2123 [doi]
    Nakamura N, Pence LM, Cao Z, Beger RD., Distinct lipid signatures are identified in the plasma of rats with chronic inflammation induced by estradiol benzoate and sex hormones, Metabolomics. 2020 Sep 7;16(9):95. doi: 10.1007/s11306-020-01715-w.
    Kulkarni, K. H., Yang, Z., Niu, T., & Hu, M. (2012), Effects of estrogen and estrus cycle on pharmacokinetics, absorption, and disposition of genistein in female sprague-dawley rats., Journal of Agricultural and Food Chemistry, 60(32), 7949-7956. doi:10.1021/jf204755g [doi]
    Klukovich, Rachel; Nilsson, Eric; Sadler-Riggleman, Ingrid; Beck, Daniel; Xie, Yeming; Yan, Wei; Skinner, Michael K;, Environmental Toxicant Induced Epigenetic Transgenerational Inheritance of Prostate Pathology and Stromal-Epithelial Cell Epigenome and Transcriptome Alterations: Ancestral Origins of Prostate Disease., Scientific reports Vol.9, 2019
    Ben Maamar, Millissia; King, Stephanie E; Nilsson, Eric; Beck, Daniel; Skinner, Michael K;, Epigenetic transgenerational inheritance of parent-of-origin allelic transmission of outcross pathology and sperm epimutations., Developmental biology Vol.108, 2019
    Sadler-Riggleman, Ingrid; Klukovich, Rachel; Nilsson, Eric; Beck, Daniel; Xie, Yeming; Yan, Wei; Skinner, Michael K, Epigenetic transgenerational inheritance of testis pathology and Sertoli cell epimutations: generational origins of male infertility., Environmental epigenetics Vol.5, 2019
    Frawley RP, Witt KL, Cunny H, Germolec DR, Jackson-Humbles D, Malarkey D, Shockley KR, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling GE, Manheng W, Surh II, White K Jr, Auerbach SS., Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies, Toxicology. 2020 Aug;441:152474. doi: 10.1016/j.tox.2020.152474. Epub 2020 May 5.
    Gohar EY, Daugherty EM, Aceves JO, Sedaka R, Obi IE, Allan JM, Soliman RH, Jin C, De Miguel C, Lindsey SH, Pollock JS, Pollock DM., Evidence for G-Protein-Coupled Estrogen Receptor as a Pronatriuretic Factor, J Am Heart Assoc. 2020 May 18;9(10):e015110. doi: 10.1161/JAHA.119.015110. Epub 2020 May 10.
    Gohar EY, Pollock DM., Functional Interaction of Endothelin Receptors in Mediating Natriuresis Evoked by G Protein-Coupled Estrogen Receptor 1, J Pharmacol Exp Ther. 2021 Jan;376(1):98-105. doi: 10.1124/jpet.120.000322. Epub 2020 Oct 30.
    Nakamura N, Vijay V, Sloper DT., Gene expression profiling in dorsolateral prostates of prepubertal and adult Sprague-Dawley rats dosed with estradiol benzoate, estradiol, and testosterone, J Toxicol Sci. 2020;45(8):435-447. doi: 10.2131/jts.45.435.
    Gao, H., Yallampalli, U., & Yallampalli, C. (2012)., Gestational protein restriction reduces expression of Hsd17b2 in rat placental labyrinth., Biology of Reproduction, 87(3), 68. doi:biolreprod.112.100479 [pii]
    Hanson AE, Perusquia M, Stallone JN., Hypogonadal hypertension in male Sprague-Dawley rats is renin-angiotensin system-dependent: role of endogenous androgens, Biol Sex Differ. 2020 Aug 26;11(1):48. doi: 10.1186/s13293-020-00324-5.
    Beverly, Brandiese E J; Furr, Johnathan R; Lambright, Christy S; Wilson, Vickie S; McIntyre, Barry S; Foster, Paul M D; Travlos, Greg; Earl Gray, L;, In utero exposure to simvastatin reduces postnatal survival and permanently alters reproductive tract development in the Crl:CD(SD) male rat., Toxicology and applied pharmacology Vol.365, 2019
    Gordon, E. E., Reinking, B. E., Hu, S., Yao, J., Kua, K. L., Younes, A. K., . . . Norris, A. W. (2015), Maternal hyperglycemia directly and rapidly induces cardiac septal overgrowth in fetal rats., Journal of Diabetes Research, 2015, 479565. doi:10.1155/2015/479565 [doi]
    Gao, H., Yallampalli, U., & Yallampalli, C. (2012), Maternal protein restriction reduces expression of angiotensin I-converting enzyme 2 in rat placental labyrinth zone in late pregnancy., Biology of Reproduction, 86(2), 31. doi:10.1095/biolreprod.111.094607 [doi]
    Behl M, Willson CJ, Cunny H, Foster PMD, McIntyre B, Shackelford C, Shockley KR, McBride S, Turner K, Waidyanatha S, Blystone CR., Multigenerational reproductive assessment of 4-methylimidazole administered in the diet to Hsd:Sprague Dawley SD rats, Reprod Toxicol. 2020 Dec;98:13-28. doi: 10.1016/j.reprotox.2020.03.005. Epub 2020 Mar 27.
    Mohr, M. A., Garcia, F. L., DonCarlos, L. L., & Sisk, C. L. (2016)., Neurons and glial cells are added to the female rat anteroventral periventricular nucleus during puberty, Endocrinology, 157(6), 2393-2402. doi:10.1210/en.2015-2012 [doi]
    National Toxicology Program., NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley(ÂŽ) SD(ÂŽ)) Rats (Gavage Studies): DART Report 02, Research Triangle Park (NC): National Toxicology Program; 2020 Jun.
    Tassinari, R., Cubadda, F., Moracci, G., Aureli, F., D'Amato, M., Valeri, M., . . . Maranghi, F. (2014)., Oral, short-term exposure to titanium dioxide nanoparticles in sprague-dawley rat: Focus on reproductive and endocrine systems and spleen, Nanotoxicology, 8(6), 654-662. doi:10.3109/17435390.2013.822114 [doi]
    Watson ATD, Sutherland VL, Cunny H, Miller-Pinsler L, Furr J, Hebert C, Collins B, Waidyanatha S, Smith L, Vinke T, Aillon K, Xie G, Shockley KR, McIntyre BS., Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat, Toxicol Sci. 2020 Jul 1;176(1):65-73. doi: 10.1093/toxsci/kfaa061.
    Shawky NM, Patil CN, Dalmasso C, Maranon RO, Romero DG, Drummond H, Reckelhoff JF., Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension, Hypertension. 2020 Sep;76(3):943-952. doi: 10.1161/HYPERTENSIONAHA.120.15504. Epub 2020 Aug 3.
    Sathishkumar, K., Elkins, R., Yallampalli, U., & Yallampalli, C. (2012), Protein restriction during pregnancy induces hypertension in adult female rat offspring--influence of oestradiol, The British Journal of Nutrition, 107(5), 665-673. doi:10.1017/S0007114511003448 [doi]
    Gohar EY, Kasztan M, Zhang S, Inscho EW, Pollock DM., Role for ovarian hormones in purinoceptor-dependent natriuresis, Biol Sex Differ. 2020 Sep 14;11(1):52. doi: 10.1186/s13293-020-00329-0.
    Liu CM, Davis EA, Suarez AN, Wood RI, Noble EE, Kanoski SE., Sex Differences and Estrous Influences on Oxytocin Control of Food Intake, Neuroscience. 2020 Nov 1;447:63-73. doi: 10.1016/j.neuroscience.2019.10.020. Epub 2019 Nov 15.
    Heath, J. C., Abdelmageed, Y., Braden, T. D., & Goyal, H. O. (2012)., The effects of chronic ingestion of mercuric chloride on fertility and testosterone levels in male sprague dawley rats., Journal of Biomedicine & Biotechnology, 2012, 815186. doi:10.1155/2012/815186 [doi]
    Heath, J. C., Abdelmageed, Y., Braden, T. D., Nichols, A. C., & Steffy, D. A. (2009)., The effects of chronic mercuric chloride ingestion in female sprague-dawley rats on fertility and reproduction., Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 47(7), 1600-1605. doi:10.1016/j.fct.2009.04.007 [doi]
    Spradley FT, Ge Y, Granger JP, Chade AR., Utero-placental vascular remodeling during late gestation in Sprague-Dawley rats, Pregnancy Hypertens. 2020 Apr;20:36-43. doi: 10.1016/j.preghy.2020.02.007. Epub 2020 Mar 3.
    Dungar BM, Schupbach CD, Jacobson JR, Kopf PG., Adrenal Corticosteroid Perturbation by the Endocrine Disruptor BDE-47 in a Human Adrenocortical Cell Line and Male Rats, Endocrinology. 2021 Nov 1;162(11):bqab160. doi: 10.1210/endocr/bqab160.
    Gray LE, Lambright CS, Conley JM, Evans N, Furr JR, Hannas BR, Wilson VS, Sampson H, Foster PMD., Genomic and Hormonal Biomarkers of Phthalate-Induced Male Rat Reproductive Developmental Toxicity Part II: A Targeted RT-qPCR Array Approach That Defines a Unique Adverse Outcome Pathway, Toxicol Sci. 2021 Aug 3;182(2):195-214. doi: 10.1093/toxsci/kfab053.
    Zakerkish F, Soriano MJ, Novella-Mestre E, Brännström M, Díaz-García C., Differential effects of the immunosuppressive calcineurin inhibitors cyclosporine-A and tacrolimus on ovulation in a murine model, Hum Reprod Open. 2021 May 11;2021(2):hoab012. doi: 10.1093/hropen/hoab012. eCollection 2021.
    Pruett JE, Torres Fernandez ED, Everman SJ, Vinson RM, Davenport K, Logan MK, Ye SA, Romero DG, Yanes Cardozo LL., Impact of SGLT-2 Inhibition on Cardiometabolic Abnormalities in a Rat Model of Polycystic Ovary Syndrome, Int J Mol Sci. 2021 Mar 4;22(5):2576. doi: 10.3390/ijms22052576.
    Nakamura N, Sloper DT., Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax™ I, Birth Defects Res. 2021 Mar;113(4):359-370. doi: 10.1002/bdr2.1859. Epub 2020 Dec 21.
    Katri A, Reker D, Karsdal MA, Bay-Jensen AC, Henriksen K., Treatment with a dual amylin and calcitonin receptor agonist improves metabolic health in an old, obese, and ovariectomized rat model, Menopause. 2021 Jan 4;28(4):423-430. doi: 10.1097/GME.0000000000001722.
    Gohar EY, Pollock DM., Functional Interaction of Endothelin Receptors in Mediating Natriuresis Evoked by G Protein-Coupled Estrogen Receptor 1, J Pharmacol Exp Ther. 2021 Jan;376(1):98-105. doi: 10.1124/jpet.120.000322. Epub 2020 Oct 30.
    Iqbal, K., Pierce, S., Kozai, K. et al., Evaluation of Placentation and the Role of the Aryl Hydrocarbon Receptor Pathway in a Rat Model of Dioxin Exposure, Environmental Health Perspectives 129:11 CID: 117001

    Surgical

    Benmansour, S., Arroyo, L. D., & Frazer, A. (2016)., Comparison of the antidepressant-like effects of estradiol and that of selective serotonin reuptake inhibitors in middle-aged ovariectomized rats., Frontiers in Aging Neuroscience, 8, 311. doi:10.3389/fnagi.2016.00311 [doi]
    Ji Y, Hu B, Klontz C, Li J, Dessem D, Dorsey SG, Traub RJ., Peripheral mechanisms contribute to comorbid visceral hypersensitivity induced by preexisting orofacial pain and stress in female rats, Neurogastroenterol Motil. 2020 Jul;32(7):e13833. doi: 10.1111/nmo.13833. Epub 2020 Mar 10.
    Hay M, Polt R, Heien ML, Vanderah TW, Largent-Milnes TM, Rodgers K, Falk T, Bartlett MJ, Doyle KP, Konhilas JP., A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction, J Pharmacol Exp Ther. 2019 Apr;369(1):9-25. doi: 10.1124/jpet.118.254854. Epub 2019 Feb 1.
    Sharma PK, Avula B, Panda A, Wang YH, Khan IA, Murthy SN., A sensitive bioanalytical method for quantitative determination of resiniferatoxin in rat plasma using ultra-high performance liquid chromatography coupled to tandem mass spectrometry and its application in pharmacokinetic study, J Pharm Biomed Anal. 2019 Feb 20;165:284-291. doi: 10.1016/j.jpba.2018.12.024. Epub 2018 Dec 14.
    Wright DM, Small KM, Nag S, Mokha SS., Activation of Membrane Estrogen Receptors Attenuates NOP-Mediated Tactile Antihypersensitivity in a Rodent Model of Neuropathic Pain, Brain Sci. 2019 Jun 21;9(6):147. doi: 10.3390/brainsci9060147.
    Katyayan KK, Hui YH., An evaluation of metabolite profiling of six drugs using dried blood spot, Xenobiotica. 2019 Dec;49(12):1458-1469. doi: 10.1080/00498254.2019.1572938. Epub 2019 Feb 18.
    Cao S, Wastney ME, Lachcik PJ, Xiao HH, Weaver CM, Wong MS., Both Oleanolic Acid and a Mixture of Oleanolic and Ursolic Acids Mimic the Effects of Fructus ligustri lucidi on Bone Properties and Circulating 1,25-Dihydroxycholecalciferol in Ovariectomized Rats, J Nutr. 2018 Dec 1;148(12):1895-1902. doi: 10.1093/jn/nxy242.
    Shao XM, Liu S, Lee ES, Fung D, Pei H, Liang J, Mudgway R, Zhang J, Feldman JL, Zhu Y, Louie S, Xie XS., Chronic intermittent nicotine delivery via lung alveolar region-targeted aerosol technology produces circadian pharmacokinetics in rats resembling human smokers, J Appl Physiol (1985). 2018 Nov 1;125(5):1555-1562. doi: 10.1152/japplphysiol.00357.2018. Epub 2018 Sep 20.
    Sanna F, Bratzu J, Piludu MA, Corda MG, Melis MR, Giorgi O, Argiolas A., Dopamine, Noradrenaline and Differences in Sexual Behavior between Roman High and Low Avoidance Male Rats: A Microdialysis Study in the Medial Prefrontal Cortex, Front Behav Neurosci. 2017 Jun 7;11:108. doi: 10.3389/fnbeh.2017.00108. eCollection 2017.
    Huijgens PT, Snoeren EMS, Meisel RL, Mermelstein PG., Effects of gonadectomy and dihydrotestosterone on neuronal plasticity in motivation and reward related brain regions in the male rat, J Neuroendocrinol. 2021 Jan;33(1):e12918. doi: 10.1111/jne.12918. Epub 2020 Dec 19.
    Radford KD, Park TY, Jaiswal S, Pan H, Knutsen A, Zhang M, Driscoll M, Osborne-Smith LA, Dardzinski BJ, Choi KH., Enhanced fear memories and brain glucose metabolism (18F-FDG-PET) following sub-anesthetic intravenous ketamine infusion in Sprague-Dawley rats, Transl Psychiatry. 2018 Nov 30;8(1):263. doi: 10.1038/s41398-018-0310-8.
    Martinez LA, Gross KS, Himmler BT, Emmitt NL, Peterson BM, Zlebnik NE, Foster Olive M, Carroll ME, Meisel RL, Mermelstein PG., Estradiol Facilitation of Cocaine Self-Administration in Female Rats Requires Activation of mGluR5, eNeuro. 2016 Oct 25;3(5):ENEURO.0140-16.2016. doi: 10.1523/ENEURO.0140-16.2016. eCollection 2016 Sep-Oct.
    Robinson DL Jr, Nag S, Mokha SS., Estrogen facilitates and the kappa and mu opioid receptors mediate antinociception produced by intrathecal (-)-pentazocine in female rats, Behav Brain Res. 2016 Oct 1;312:163-8. doi: 10.1016/j.bbr.2016.06.019. Epub 2016 Jun 14.
    Dantzler HA, Kline DD., Exaggerated potassium current reduction by oxytocin in visceral sensory neurons following chronic intermittent hypoxia, Auton Neurosci. 2020 Dec;229:102735. doi: 10.1016/j.autneu.2020.102735. Epub 2020 Sep 28.
    Leber A, Hontecillas R, Zoccoli-Rodriguez V, Ehrich M, Chauhan J, Bassaganya-Riera J., Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1, Drug Chem Toxicol. 2019 Oct 25:1-6. doi: 10.1080/01480545.2019.1679828. Online ahead of print.
    Kao HW, Lin YY, Gwathney WJ, Hong K., Formulation and evaluation of multilamellar vesicles ropivacaine in pain management, Int J Nanomedicine. 2019 Sep 27;14:7891-7901. doi: 10.2147/IJN.S215952. eCollection 2019.
    Bakewell SJ, Carie A, Costich TL, Sethuraman J, Semple JE, Sullivan B, Martinez GV, Dominguez-Viqueira W, Sill KN., Imaging the delivery of drug-loaded, iron-stabilized micelles, Nanomedicine. 2017 May;13(4):1353-1362. doi: 10.1016/j.nano.2017.01.009. Epub 2017 Jan 20.
    Cladis DP, Debelo H, Lachcik PJ, Ferruzzi MG, Weaver CM., Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats, Mol Nutr Food Res. 2020 Jun;64(12):e2000031. doi: 10.1002/mnfr.202000031. Epub 2020 May 27.
    Roberts SM, Rohr AC, Mikheev VB, Munson J, Sabo-Attwood T., Influence of airborne particulates on respiratory tract deposition of inhaled toluene and naphthalene in the rat, Inhal Toxicol. 2018 Jan;30(1):19-28. doi: 10.1080/08958378.2018.1438539. Epub 2018 Feb 21.
    Mackert GA, Schulte M, Hirche C, Kotsougiani D, Vogelpohl J, Hoener B, Fiebig T, Kirschner S, Brockmann MA, Lehnhardt M, Kneser U, Harhaus L., Low-energy extracorporeal shockwave therapy (ESWT) improves metaphyseal fracture healing in an osteoporotic rat model, PLoS One. 2017 Dec 12;12(12):e0189356. doi: 10.1371/journal.pone.0189356. eCollection 2017.
    Gross KS, Moore KM, Meisel RL, Mermelstein PG., mGluR5 Mediates Dihydrotestosterone-Induced Nucleus Accumbens Structural Plasticity, but Not Conditioned Reward, Front Neurosci. 2018 Nov 20;12:855. doi: 10.3389/fnins.2018.00855. eCollection 2018.
    Rioux N, Smith S, Korpal M, O'Shea M, Prajapati S, Zheng GZ, Warmuth M, Smith PG., Nonclinical pharmacokinetics and in vitro metabolism of H3B-6545, a novel selective ERÎą covalent antagonist (SERCA), Cancer Chemother Pharmacol. 2019 Jan;83(1):151-160. doi: 10.1007/s00280-018-3716-3. Epub 2018 Nov 1.
    Grecco GG, Kisor DF, Sprague JE., Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats, Data Brief. 2018 Oct 25;21:1045-1050. doi: 10.1016/j.dib.2018.10.073. eCollection 2018 Dec.
    Vigiola Cruz M, Carney BC, Luker JN, Monger KW, Vazquez JS, Moffatt LT, Johnson LS, Shupp JW., Plasma Ameliorates Endothelial Dysfunction in Burn Injury, J Surg Res. 2019 Jan;233:459-466. doi: 10.1016/j.jss.2018.08.027. Epub 2018 Sep 22.
    Sarkar M, Grossman RG, Toups EG, Chow DS., Rational design and development of a stable liquid formulation of riluzole and its pharmacokinetic evaluation after oral and IV administrations in rats, Eur J Pharm Sci. 2018 Dec 1;125:1-10. doi: 10.1016/j.ejps.2018.09.004. Epub 2018 Sep 8.
    Hill K, Walker SN, Salminen A, Chung HL, Li X, Ezzat B, Miller JJ, DesOrmeaux JS, Zhang J, Hayden A, Burgin T, Piraino L, May MN, Gaborski TR, Roussie JA, Taylor J, DiVincenti L Jr, Shestopalov AA, McGrath JL, Johnson DG., Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis, Adv Healthc Mater. 2020 Feb;9(4):e1900750. doi: 10.1002/adhm.201900750. Epub 2020 Jan 15.
    Cao J, Ng M, Felmlee MA., Sex Hormones Regulate Rat Hepatic Monocarboxylate Transporter Expression and Membrane Trafficking, J Pharm Pharm Sci. 2017;20(1):435-444. doi: 10.18433/J3CH29.
    Waldron RT, Chen Y, Pham H, Go A, Su HY, Hu C, Wen L, Husain SZ, Sugar CA, Roos J, Ramos S, Lugea A, Dunn M, Stauderman K, Pandol SJ., The Orai Ca(2+) channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis, J Physiol. 2019 Jun;597(12):3085-3105. doi: 10.1113/JP277856. Epub 2019 May 22.
    Kim YJ, Tu Y, Chow DS., Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats, J Pharm Biomed Anal. 2018 Nov 30;161:122-128. doi: 10.1016/j.jpba.2018.07.058. Epub 2018 Aug 2.
    Sharp AM, Lertphinyowong S, Yee SS, Paredes D, Gelfond J, Johnson-Pais TL, Leach RJ, Liss M, Risinger AL, Sullivan AC, Thompson IM, Morilak DA., Vortioxetine reverses medial prefrontal cortex-mediated cognitive deficits in male rats induced by castration as a model of androgen deprivation therapy for prostate cancer, Psychopharmacology (Berl). 2019 Nov;236(11):3183-3195. doi: 10.1007/s00213-019-05274-4. Epub 2019 May 28.
    Cladis DP, Simpson AMR, Cooper KJ, Nakatsu CH, Ferruzzi MG, Weaver CM., Blueberry polyphenols alter gut microbiota & phenolic metabolism in rats., Food Funct. 2021 Mar 21;12(6):2442-2456. doi: 10.1039/d0fo03457f. Epub 2021 Feb 25.
    Crowley ML, Restrepo LF, Gamez-Jimenez LR, Patel A, Braun T, Pallares VLC, Ho NP, Reeves ME, McCurdy CR, McMahon LR, Hiranita T., The use of hypercapnic conditions to assess opioid-induced respiratory depression in rats., J Pharmacol Toxicol Methods. 2021 Sep-Oct;111:107101. doi: 10.1016/j.vascn.2021.107101. Epub 2021 Jul 7.
    Berthold EC, Kamble SH, Raju KS, King TI, Popa R, Sharma A, León F, Avery BA, McMahon LR, McCurdy CR., Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method., J Pharm Biomed Anal. 2021 Feb 5;194:113778. doi: 10.1016/j.jpba.2020.113778. Epub 2020 Nov 21.
    Waidyanatha S, Mutlu E, Gibbs S, Pierfelice J, Smith JP, Burback B, Blystone CT., Phenolic benzotriazoles: a class comparison of toxicokinetics of ultraviolet-light absorbers in male rats., Xenobiotica. 2021 Jul;51(7):831-841. doi: 10.1080/00498254.2021.1927239. Epub 2021 May 24.
    Zhao M, Zhang F, Zarnowski R, Barns K, Jones R, Fossen J, Sanchez H, Rajski SR, Audhya A, Bugni TS, Andes DR., Turbinmicin inhibits Candida biofilm growth by disrupting fungal vesicle-mediated trafficking, J Clin Invest. 2021 Mar 1;131(5):e145123. doi: 10.1172/JCI145123.
    Garcia J, Mankin P, Gnanamony M, de Alarcon PA., Evaluation of angiogenic signaling molecules associated with reactive thrombocytosis in an iron-deficient rat model, Pediatr Res. 2021 Aug;90(2):341-346. doi: 10.1038/s41390-020-01318-0. Epub 2021 Jan 19.
    Sharma PK, Kushwaha A, Repka MA, Murthy SN, Formulation development and pharmacokinetic investigation of self-assembled hybrid niosomes for oral delivery of 17-Hydroxyprogesterone caproate, Journal of Drug Delivery Science and Technology Volume 61, February 2021, 102215
    Liu C, Cui Z, Yan Y, Wu NL, Li L, Ying Q, Peng L., An optimized proliferation system of embryonic stem cells for generating the rat model with large fragment modification., Biochem Biophys Res Commun. 2021 Sep 24;571:8-13. doi: 10.1016/j.bbrc.2021.07.053. Epub 2021 Jul 20.
    Ikeda K, Osuru HP, Thiele RH, Dual One-Way Study of Sepsis Survivability Study in Rats Exposed to Cecal Ligation and Puncture with Propofol or Isoflurane, Preprint from Research Square, 18 Nov 2021 DOI: 10.21203/rs.3.rs-1072022/v1 PPR: PPR421944 
    Liu J, Kim EK, Ni A, Kim YR, Zheng F, Lee BS, Kim DG., Multiscale characterization of ovariectomized rat femur, J Biomech. 2021 Jun 9;122:110462. doi: 10.1016/j.jbiomech.2021.110462. Epub 2021 Apr 18.
    Ahmed F, Rahman Md, Thompson R, Bereiter DA., Role of Connexin 43 in an Inflammatory Model for TMJ Hyperalgesia, Front. Pain Res., 03 August 2021.

    Teratology

    Turano, A., Lawrence, J. H., & Schwarz, J. M. (2017), Activation of neonatal microglia can be influenced by other neural cells, Neuroscience Letters, 657, 32-37. doi:S0304-3940(17)30624-9 [pii]
    Vaka VR, Cunningham MW, Deer E, Franks M, Ibrahim T, Amaral LM, Usry N, Cornelius DC, Dechend R, Wallukat G, LaMarca BD., Blockade of endogenous angiotensin II type I receptor agonistic autoantibody activity improves mitochondrial reactive oxygen species and hypertension in a rat model of preeclampsia, Am J Physiol Regul Integr Comp Physiol. 2020 Feb 1;318(2):R256-R262. doi: 10.1152/ajpregu.00179.2019. Epub 2019 Nov 13.
    Gosemann, J. H., Friedmacher, F., Fujiwara, N., Alvarez, L. A., Corcionivoschi, N., & Puri, P. (2013)., Disruption of the bone morphogenetic protein receptor 2 pathway in nitrofen-induced congenital diaphragmatic hernia., Birth Defects Research.Part B, Developmental and Reproductive Toxicology, 98(4), 304-309. doi:10.1002/bdrb.21065 [doi]
    Sadowski, R. N., Wise, L. M., Park, P. Y., Schantz, S. L., & Juraska, J. M. (2014)., Early exposure to bisphenol A alters neuron and glia number in the rat prefrontal cortex of adult males, but not females., Neuroscience, 279, 122-131. doi:10.1016/j.neuroscience.2014.08.038 [doi]
    Nakamura, N., Inselman, A. L., White, G. A., Chang, C. W., Trbojevich, R. A., Sephr, E., . . . Hansen, D. K. (2015)., Effects of maternal and lactational exposure to 2-hydroxy-4-methoxybenzone on development and reproductive organs in male and female rat offspring., Birth Defects Research.Part B, Developmental and Reproductive Toxicology, 104(1), 35-51. doi:10.1002/bdrb.21137 [doi]
    Krishnan, K., Mittal, N., Thompson, L. M., Rodriguez-Santiago, M., Duvauchelle, C. L., Crews, D., & Gore, A. C. (2018), Effects of the endocrine-disrupting chemicals, vinclozolin and polychlorinated biphenyls, on physiological and sociosexual phenotypes in F2 generation sprague-dawley rats, Environmental Health Perspectives, 126(9), 97005. doi:10.1289/EHP3550 [doi]
    Mowery, T. M., Wilson, S. M., Kostylev, P. V., Dina, B., Buchholz, J. B., Prieto, A. L., & Garraghty, P. E. (2015), Embryological exposure to valproic acid disrupts morphology of the deep cerebellar nuclei in a sexually dimorphic way., International Journal of Developmental Neuroscience : The Official Journal of the International Society for Developmental Neuroscience, 40, 15-23. doi:10.1016/j.ijdevneu.2014.10.003 [doi]
    Baack, M. L., Wang, C., Hu, S., Segar, J. L., & Norris, A. W. (2014), Hyperglycemia induces embryopathy, even in the absence of systemic maternal diabetes: An in vivo test of the fuel mediated teratogenesis hypothesis, Reproductive Toxicology (Elmsford, N.Y.), 46, 129-136. doi:10.1016/j.reprotox.2014.03.013 [doi]
    Yang W, Li Q, Duncan JW, Bakrania BA, Bradshaw JL, Granger JP, Rana S, Spradley FT., Luteolin-induced vasorelaxation in uterine arteries from normal pregnant rats, Pregnancy Hypertens. 2020 Oct 23;23:11-17. doi: 10.1016/j.preghy.2020.10.008. Online ahead of print.
    Tavanasefat H, Li F, Koyano K, Gourtani BK, Marty V, Mulpuri Y, Lee SH, Shin KH, Wong DTW, Xiao X, Spigelman I, Kim Y., Molecular consequences of fetal alcohol exposure on amniotic exosomal miRNAs with functional implications for stem cell potency and differentiation, PLoS One. 2020 Nov 16;15(11):e0242276. doi: 10.1371/journal.pone.0242276. eCollection 2020.
    Gokulakrishnan, G., Chang, X., Fleischmann, R., & Fiorotto, M. L. (2017)., Precocious glucocorticoid exposure reduces skeletal muscle satellite cells in the fetal rat., The Journal of Endocrinology, 232(3), 561-572. doi:10.1530/JOE-16-0372 [doi]
    Hernandez Scudder ME, Weinberg A, Thompson L, Crews D, Gore AC., Prenatal EDCs Impair Mate and Odor Preference and Activation of the VMN in Male and Female Rats, Endocrinology. 2020 Sep 1;161(9):bqaa124. doi: 10.1210/endocr/bqaa124.
    Vorhees, C. V., Graham, D. L., Braun, A. A., Schaefer, T. L., Skelton, M. R., Richtand, N. M., & Williams, M. T. (2015)., Prenatal immune challenge in rats: Effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine., Neurotoxicology and Teratology, 47, 54-65. doi:10.1016/j.ntt.2014.10.007 [doi]
    Friedmacher, F., Fujiwara, N., Hofmann, A. D., Takahashi, H., Alvarez, L. A., Gosemann, J. H., & Puri, P. (2014)., Prenatal retinoic acid increases lipofibroblast expression in hypoplastic rat lungs with experimental congenital diaphragmatic hernia., Journal of Pediatric Surgery, 49(6), 876-81; discussion 881. doi:10.1016/j.jpedsurg.2014.01.017 [doi]
    Borracci, P., & Carratu, M. R. (2014)., Rat embryo exposure to all-trans retinoic acid results in long-term cognitive deficits, European Review for Medical and Pharmacological Sciences, 18(1), 28-33. doi:6446 [pii]
    Manikkam, M., Guerrero-Bosagna, C., Tracey, R., Haque, M. M., & Skinner, M. K. (2012)., Transgenerational actions of environmental compounds on reproductive disease and identification of epigenetic biomarkers of ancestral exposures., PloS One, 7(2), e31901. doi:10.1371/journal.pone.0031901 [doi]
    Spradley FT, Ge Y, Granger JP, Chade AR., Utero-placental vascular remodeling during late gestation in Sprague-Dawley rats, Pregnancy Hypertens. 2020 Apr;20:36-43. doi: 10.1016/j.preghy.2020.02.007. Epub 2020 Mar 3.
    Deer E, Jones J, Cornelius DC, Comley K, Herrock O, Campbell N, Fitzgerald S, Ibrahim T, LaMarca B, Amaral LM., Progesterone Induced Blocking Factor Reduces Hypertension and Placental Mitochondrial Dysfunction in Response to sFlt-1 during Pregnancy, Cells. 2021 Oct 20;10(11):2817. doi: 10.3390/cells10112817.
    Chalil D, Aristizabal-Henao JJ, Chalil A, Stark KD., Evidence of multiple hepatic mechanisms to mobilize docosahexaenoic acid into dam plasma during pregnancy in chow-fed sprague dawley rats, Prostaglandins Leukot Essent Fatty Acids. 2021 Aug;171:102317. doi: 10.1016/j.plefa.2021.102317. Epub 2021 Jun 29.
    Ishimwe JA, Akinleye A, Johnson AC, Garrett MR, Sasser JM., Gestational gut microbial remodeling is impaired in a rat model of preeclampsia superimposed on chronic hypertension, Physiol Genomics. 2021 Mar 1;53(3):125-136. doi: 10.1152/physiolgenomics.00121.2020. Epub 2021 Jan 25.
    Yang W, Li Q, Duncan JW, Bakrania BA, Bradshaw JL, Granger JP, Rana S, Spradley FT., Luteolin-induced vasorelaxation in uterine arteries from normal pregnant rats, Pregnancy Hypertens. 2021 Mar;23:11-17. doi: 10.1016/j.preghy.2020.10.008. Epub 2020 Oct 23.
    Traccis F, Serra V, Sagheddu C, Congiu M, Saba P, Giua G, Devoto P, Frau R, Cheer JF, Melis M., Prenatal THC Does Not Affect Female Mesolimbic Dopaminergic System in Preadolescent Rats, Int J Mol Sci. 2021 Feb 7;22(4):1666. doi: 10.3390/ijms22041666.
    Maeda KJ, McClung DM, Showmaker KC, Warrington JP, Ryan MJ, Garrett MR, Sasser JM., Endothelial cell disruption drives increased blood-brain barrier permeability and cerebral edema in the Dahl SS/jr rat model of superimposed preeclampsia, Am J Physiol Heart Circ Physiol. 2021 Feb 1;320(2):H535-H548. doi: 10.1152/ajpheart.00383.2020. Epub 2020 Dec 4.
    Waidyanatha S, Collins BJ, Cunny H, Aillon K, Riordan F, Turner K, McBride S, Betz L, Sutherland V., An investigation of systemic exposure to bisphenol AF during critical periods of development in the rat, Toxicol Appl Pharmacol. 2021 Jan 15;411:115369. doi: 10.1016/j.taap.2020.115369. Epub 2020 Dec 15.
    Dagher JB, Hahn-Townsend CK, Kaimal A, Mansi MA, Henriquez JE, Tran DG, Laurent CR, Bacak CJ, Buechter HE, Cambric C, Spivey J, Chuang YJ, Campbell EJ, Mandal A, Mohankumar PS, MohanKumar SMJ., Independent and combined effects of Bisphenol A and Diethylhexyl Phthalate on gestational outcomes and offspring development in Sprague-Dawley rats, Chemosphere. 2021 Jan;263:128307. doi: 10.1016/j.chemosphere.2020.128307. Epub 2020 Sep 14.
    Deer E, Reeve KE, Amaral L, Vaka VR, Franks M, Campbell N, Fitzgerald S, Herrock O, Ibrahim T, Cornelius D, LaMarca B., CD4+ T cells cause renal and placental mitochondrial oxidative stress as mechanisms of hypertension in response to placental ischemia, Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F47-F54. doi: 10.1152/ajprenal.00398.2020. Epub 2020 Nov 16.
    Kuna M, Dhakal P, Iqbal K, Dominguez EM, Kent LN, Muto M, Moreno-Irusta A, Kozai K, Varberg KM, Okae H, Arima T, Sucov HM, Soares MJ., CITED2 is a conserved regulator of the uterine-placental interface, Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2213622120. doi: 10.1073/pnas.2213622120. Epub 2023 Jan 10.
    Witchey SK, Sutherland V, Collins B, Roberts G, Shockley KR, Vallant M, Krause J, Cunny H, Waidyanatha S, Mylchreest E, Sparrow B, Moyer R, Behl M., Reproductive and developmental toxicity following exposure to organophosphate ester flame retardants and plasticizers, triphenyl phosphate and isopropylated phenyl phosphate, in Sprague Dawley rats, Toxicol Sci. 2022 Dec 23:kfac135. doi: 10.1093/toxsci/kfac135. Online ahead of print.
    Bake S, Hurst DA, Miranda RC, Sohrabji F., Prenatal alcohol exposure exacerbates acute sensorimotor deficits and impedes long-term behavioral recovery from the effects of an adult-onset cerebrovascular ischemic stroke, Alcohol Clin Exp Res. 2022 Dec;46(12):2267-2279. doi: 10.1111/acer.14952. Epub 2022 Nov 24.
    Gopalakrishnan K, Mishra JS, Ross JR, Abbott DH, Kumar S., Hyperandrogenism diminishes maternal-fetal fatty acid transport by increasing FABP4-mediated placental lipid accumulation†, Biol Reprod. 2022 Aug 9;107(2):514-528. doi: 10.1093/biolre/ioac059.
    Mariacarmela G, Milena E, Sveinbjorn G, Daniel H, Maurizio M., Placental protein 13 dilation of pregnant rat uterine vein is endothelium dependent and involves nitric oxide/calcium activated potassium channels signals, Placenta. 2022 Aug;126:233-238. doi: 10.1016/j.placenta.2022.07.001. Epub 2022 Jul 16.
    Wang R, Martin CD, Lei AL, Hausknecht KA, Turk M, Micov V, Kwarteng F, Ishiwari K, Oubraim S, Wang AL, Richards JB, Haj-Dahmane S, Shen RY., Prenatal ethanol exposure impairs sensory processing and habituation to visual stimuli, effects normalized by enrichment of postnatal environmental, Alcohol Clin Exp Res. 2022 May;46(5):891-906. doi: 10.1111/acer.14818. Epub 2022 Apr 18.
    Gore AC, Moore T, Groom MJ, Thompson LM., Prenatal Exposure to an EDC Mixture, NeuroMix: Effects on Brain, Behavior, and Stress Responsiveness in Rats, Toxics. 2022 Mar 3;10(3):122. doi: 10.3390/toxics10030122.
    Witchey SK, Sutherland V, Collins B, Roberts G, Shockley KR, Vallant M, Krause J, Cunny H, Waidyanatha S, Mylchreest E, Sparrow B, Moyer R, Behl M., Reproductive and developmental toxicity following exposure to organophosphate ester flame retardants and plasticizers, triphenyl phosphate and isopropylated phenyl phosphate, in Sprague Dawley rats, Toxicol Sci. 2022 Dec 23:kfac135. doi: 10.1093/toxsci/kfac135. Online ahead of print.
    Itzhak I, Cohen S, Fishman S, Fishman P., A3 adenosine receptor allosteric modulator CF602 reverses erectile dysfunction in a diabetic rat model, Andrologia. 2022 Oct;54(9):e14498. doi: 10.1111/and.14498. Epub 2022 Jun 22.
    Oppong-Gyebi A, Metzger D, Vann PH, Yockey RA, Sumien N, Schreihofer DA., Dietary genistein and 17β-estradiol implants differentially influence locomotor and cognitive functions following transient focal ischemia in middle-aged ovariectomized rats at different lengths of estrogen deprivation, Horm Behav. 2022 Aug;144:105201. doi: 10.1016/j.yhbeh.2022.105201. Epub 2022 May 30.
    Cellai I, Filippi S, Comeglio P, Cipriani S, Maseroli E, Di Stasi V, Todisco T, Marchiani S, Tamburrino L, Villanelli F, Vezzani S, Corno C, Fambrini M, Guarnieri G, Sarchielli E, Morelli A, Rastrelli G, Maggi M, Vignozzi L., Testosterone positively regulates vagina NO-induced relaxation: an experimental study in rats, J Endocrinol Invest. 2022 Jun;45(6):1161-1172. doi: 10.1007/s40618-022-01743-4. Epub 2022 Jan 24.
    Rieger MM, Wong M, Burnett LA, Sesillo FB, Baynes BB, Alperin M., Mechanisms governing protective pregnancy-induced adaptations of the pelvic floor muscles in the rat preclinical model, Am J Obstet Gynecol. 2022 May;226(5):708.e1-708.e13. doi: 10.1016/j.ajog.2021.11.1353. Epub 2021 Nov 18.
    Li Y, Wei L, Meinsohn MC, Suliman R, Chauvin M, Berstler J, Hartland K, Jensen MM, Sicher NA, Nagykery N, Donahoe PK, Pepin D., A screen of repurposed drugs identifies AMHR2/MISR2 agonists as potential contraceptives, Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2122512119. doi: 10.1073/pnas.2122512119. Epub 2022 Apr 5.
    Oppong-Gyebi A, Metzger D, Doan T, Han J, Vann PH, Yockey RA, Sumien N, Schreihofer DA., Long-term hypogonadism diminishes the neuroprotective effects of dietary genistein in young adult ovariectomized rats after transient focal ischemia, J Neurosci Res. 2022 Feb;100(2):598-619. doi: 10.1002/jnr.24981. Epub 2021 Oct 28.
    Kermath BA, Thompson LM, Jefferson JR, Ward MHB, Gore AC., Transgenerational Effects of Prenatal Endocrine Disruption on Reproductive and Sociosexual Behaviors in Sprague Dawley Male and Female Rats, Toxics. 2022 Jan 20;10(2):47. doi: 10.3390/toxics10020047.

    Toxicology

    Roberts, G. K., Stout, M. D., Sayers, B., Fallacara, D. M., Hejtmancik, M. R., Waidyanatha, S., & Hooth, M. J. (2016)., 14-day toxicity studies of tetravalent and pentavalent vanadium compounds in harlan sprague dawley rats and B6C3F1/N mice via drinking water exposure, Toxicology Reports, 3, 531-538. doi:10.1016/j.toxrep.2016.05.001 [doi]
    Knudsen GA, Chapman M, Trexler AW, Juberg CT, Birnbaum LS., 2,4,6-Tribromophenol Disposition and Kinetics in Pregnant and Nursing Sprague Dawley Rats, Toxicol Sci. 2020 Nov 1;178(1):36-43. doi: 10.1093/toxsci/kfaa133.
    Trexler, Andrew W; Knudsen, Gabriel A; Nicklisch, Sascha C T; Birnbaum, Linda S; Cannon, Ronald E;, 2,4,6-Tribromophenol Exposure Decreases P-glycoprotein Transport at the Blood-Brain Barrier., Toxicological sciences : an official journal of the Society of Toxicology Vol.306, 2019
    Cladis DP, Li S, Reddivari L, Cox A, Ferruzzi MG, Weaver CM., A 90 day oral toxicity study of blueberry polyphenols in ovariectomized sprague-dawley rats, Food Chem Toxicol. 2020 May;139:111254. doi: 10.1016/j.fct.2020.111254. Epub 2020 Mar 9.
    Frank, S. J., Johansen, M. J., Martirosyan, K. S., Gagea, M., Van Pelt, C. S., Borne, A., . . . Madden, T. (2013), A biodistribution and toxicity study of cobalt dichloride-N-acetyl cysteine in an implantable MRI marker for prostate cancer treatment., International Journal of Radiation Oncology, Biology, Physics, 85(4), 1024-1030. doi:10.1016/j.ijrobp.2012.09.007 [doi]
    Joshi, P S; Sanakkayala, N; Kirkpatrick, L; Terse, P S; Nonclinical safety assessment of PF614:, A novel TAAP prodrug of oxycodone for chronic pain indication., Regulatory toxicology and pharmacology : RTP Vol.108, 2019
    Di Cesare Mannelli, L., Tenci, B., Zanardelli, M., Failli, P., & Ghelardini, C. (2015)., alpha7 nicotinic receptor promotes the neuroprotective functions of astrocytes against oxaliplatin neurotoxicity., Neural Plasticity, 2015, 396908. doi:10.1155/2015/396908 [doi]
    Maffini MV, Canatsey RD., An expanded toxicological profile of tetramethyl bisphenol F (TMBPF), a precursor for a new food-contact metal packaging coating, Food Chem Toxicol. 2020 Jan;135:110889. doi: 10.1016/j.fct.2019.110889. Epub 2019 Oct 17.
    Patlolla, A. K., Todorov, T. I., Tchounwou, P. B., van der Voet, G., & Centeno, J. A. (2012)., Arsenic-induced biochemical and genotoxic effects and distribution in tissues of sprague-dawley rats, Microchemical Journal, Devoted to the Application of Microtechniques in all Branches of Science, 105, 101-107. doi:10.1016/j.microc.2012.08.013 [doi]
    Bastaki, Maria; Mendes, Odete R; Bauter, Mark R; Taylor, Sean V;, Assessment of FD&C Yellow No. 6 (Sunset Yellow FCF) effects on sperm count, motility and viability in the rat in a 28-day toxicity study., Regulatory toxicology and pharmacology : RTP Vol.108, 2019
    Patlolla, A. K., Rondalph, J., & Tchounwou, P. B. (2017)., Biochemical and histopathological evaluation of graphene oxide in sprague-dawley rats, Austin Journal of Environmental Toxicology, 3(1) doi:1021 [pii]
    Ramot, Yuval; Kronfeld, Noam; Steiner, Michal; Klaiman, Guy; Hadid, Amir; Sudak, Michal;, Biodegradability and Safety Study of LifeMesh™, a Novel Self-adhesive Mesh, in Sprague-Dawley Rats., Toxicologic pathology Vol.47, 2019
    Huang, M C; Robinson, V G; Waidyanatha, S; Dzierlenga, A L; DeVito, M J; Eifrid, M A; Gibbs, S T; Blystone, C R, Toxicokinetics of 8:2 fluorotelomer alcohol (8:2-FTOH) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration., Toxicology reports Vol.6, 2019
    Reilly, T. P., Graziano, M. J., Janovitz, E. B., Dorr, T. E., Fairchild, C., Lee, F., . . . Tirmenstein, M. (2014)., Carcinogenicity risk assessment supports the chronic safety of dapagliflozin, an inhibitor of sodium-glucose co-transporter 2, in the treatment of type 2 diabetes mellitus, Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders, 5(1), 73-96. doi:10.1007/s13300-014-0053-3 [doi]
    Waidyanatha S, Black SR, Croutch CR, Collins BJ, Silinski MAR, Kerns S, Sutherland V, Robinson VG, Aillon K, Fernando RA, Mutlu E, Fennell TR., Comparative toxicokinetics of bisphenol S and bisphenol AF in male rats and mice following repeated exposure via feed, Xenobiotica. 2021 Feb;51(2):210-221. doi: 10.1080/00498254.2020.1829171. Epub 2020 Oct 6.
    van Ede, K. I., Andersson, P. L., Gaisch, K. P., van den Berg, M., & van Duursen, M. B. (2014)., Comparison of intake and systemic relative effect potencies of dioxin-like compounds in female rats after a single oral dose, Archives of Toxicology, 88(3), 637-646. doi:10.1007/s00204-013-1186-2 [doi]
    Zhang N, Sarkar AK, Pati D., Data set on Separase Inhibitor-Sepin-1 toxicity on organ weights, hematology and clinical parameters in Sprague-Dawley rats, Data Brief. 2020 Jan 22;29:105159. doi: 10.1016/j.dib.2020.105159. eCollection 2020 Apr.
    Gokulan K, Kumar A, Lahiani MH, Sutherland VL, Cerniglia CE, Khare S., Differential toxicological outcome of corn oil exposure in rats and mice as assessed by microbial composition, epithelial permeability and ileal mucosa associated immune status, Toxicol Sci. 2020 Dec 2:kfaa177. doi: 10.1093/toxsci/kfaa177. Online ahead of print.
    Waidyanatha S, McDonald JD, Sanders JM, Doyle-Eisele M, Moeller BC, Garner CE., Disposition and metabolism of 2,2'-dimorpholinodiethyl ether in sprague dawley rats and B6C3F1/N mice after oral, intravenous administration, and dermal application, Xenobiotica. 2020 Nov;50(11):1341-1351. doi: 10.1080/00498254.2020.1779389. Epub 2020 Jun 22.
    Waidyanatha S, Black SR, Patel PR, Watson SL, Snyder RW, Sutherland V, Stanko J, Fennell TR., Disposition and metabolism of antibacterial agent, triclocarban, in rodents; a species and route comparison, Xenobiotica. 2020 Dec;50(12):1469-1482. doi: 10.1080/00498254.2020.1779391. Epub 2020 Jun 24.
    Waidyanatha, Suramya; Black, Sherry R; Patel, Purvi R; Rider, Cynthia V; Watson, Scott L; Snyder, Rodney W; Fennell, Timothy R;, Disposition and metabolism of N-butylbenzenesulfonamide in Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans., Toxicology letters Vol.319, 2020
    Waidyanatha, Suramya; Black, Sherry R; Blystone, Chad R; Patel, Purvi R; Watson, Scott L; Snyder, Rodney W; Fennell, Timothy R;, Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans, Xenobiotica; the fate of foreign compounds in biological systems Vol.373, 2019
    Knudsen, G. A., Sanders, J. M., & Birnbaum, L. S. (2016), Disposition of the emerging brominated flame retardant, 2-ethylhexyl 2,3,4,5-tetrabromobenzoate, in female SD rats and male B6C3F1 mice: Effects of dose, route, and repeated administration., Toxicological Sciences : An Official Journal of the Society of Toxicology, 154(2), 392-402. doi:kfw176 [pii]
    Bunin, D. I., Chang, P. Y., Doppalapudi, R. S., Riccio, E. S., An, D., Jarvis, E. E., . . . Abergel, R. J. (2013)., Dose-dependent efficacy and safety toxicology of hydroxypyridinonate actinide decorporation agents in rodents: Towards a safe and effective human dosing regimen, Radiation Research, 179(2), 171-182. doi:10.1667/RR3115.1 [doi]
    Canistro, D., Vivarelli, F., Cirillo, S., Babot Marquillas, C., Buschini, A., Lazzaretti, M., . . . Paolini, M. (2017)., E-cigarettes induce toxicological effects that can raise the cancer risk, Scientific Reports, 7(1), 2028-017-02317-8. doi:10.1038/s41598-017-02317-8 [doi]
    Karuppagounder, S. S., Bhattacharya, D., Ahuja, M., Suppiramaniam, V., Deruiter, J., Clark, R., & Dhanasekaran, M. (2014)., Elucidating the neurotoxic effects of MDMA and its analogs, Life Sciences, 101(1-2), 37-42. doi:10.1016/j.lfs.2014.02.010 [doi]
    Frawley RP, Witt KL, Cunny H, Germolec DR, Jackson-Humbles D, Malarkey D, Shockley KR, Stout M, Travlos G, Buccellato M, Fallacara D, Harris S, Kissling GE, Manheng W, Surh II, White K Jr, Auerbach SS., Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies, Toxicology. 2020 Aug;441:152474. doi: 10.1016/j.tox.2020.152474. Epub 2020 May 5.
    Veronesi F, Giavaresi G, Bellini D, Casagranda V, Pressato D, Fini M., Evaluation of a new collagen-based medical device (ElastiCoÂŽ) for the treatment of acute Achilles tendon injury and prevention of peritendinous adhesions: An in vitro biocompatibility and in vivo investigation, J Tissue Eng Regen Med. 2020 Aug;14(8):1113-1125. doi: 10.1002/term.3085. Epub 2020 Jul 13.
    Kale VP, Wallery J, Novak J, Gibbs S, Bourdi M, Do MT, McKew JC, Terse PS., Evaluation of chronic toxicity of cyclocreatine, a creatine analog, in Sprague Dawley rat after oral gavage administration for up to 26 weeks, Regul Toxicol Pharmacol. 2020 Nov;117:104750. doi: 10.1016/j.yrtph.2020.104750. Epub 2020 Aug 1.
    Rider, C. V., Janardhan, K. S., Rao, D., Morrison, J. P., McPherson, C. A., & Harry, G. J. (2012)., Evaluation of N-butylbenzenesulfonamide (NBBS) neurotoxicity in sprague-dawley male rats following 27-day oral exposure, Neurotoxicology, 33(6), 1528-1535. doi:10.1016/j.neuro.2012.07.002 [doi]
    Smith-Roe, Stephanie L; Wyde, Michael E; Stout, Matthew D; Winters, John W; Hobbs, Cheryl A; Shepard, Kim G; Green, Amanda S; Kissling, Grace E; Shockley, Keith R; Tice, Raymond R; Bucher, John R; Witt, Kristine L;, Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure., Environmental and molecular mutagenesis Vol.306, 2019
    Leber A, Hontecillas R, Zoccoli-Rodriguez V, Ehrich M, Chauhan J, Bassaganya-Riera J., Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1, Drug Chem Toxicol. 2019 Oct 25:1-6. doi: 10.1080/01480545.2019.1679828. Online ahead of print.
    Roberts, G. K., Waidyanatha, S., Kissling, G. E., Fletcher, B. L., Silinski, M. A. R., Fennell, T. R., . . . Blystone, C. R. (2016)., Exposure to butyl paraben during gestation and lactation in hsd:Sprague dawley SD rats via dosed feed., Toxicology Reports, 3, 774-783. doi:10.1016/j.toxrep.2016.09.004 [doi]
    Hong, M. Y., Lumibao, J., Mistry, P., Saleh, R., & Hoh, E. (2015), Fish oil contaminated with persistent organic pollutants reduces antioxidant capacity and induces oxidative stress without affecting its capacity to lower lipid concentrations and systemic inflammation in rats, The Journal of Nutrition, 145(5), 939-944. doi:10.3945/jn.114.206607 [doi]
    Maronpot, R. R., Hobbs, C. A., Davis, J., Swartz, C., Boyle, M., Koyanagi, M., & Hayashi, S. M. (2016)., Genetic and rat toxicity studies of cyclodextrin glucanotransferase., Toxicology Reports, 3, 381-392. doi:10.1016/j.toxrep.2016.03.002 [doi]
    Patlolla, A. K., Hackett, D., & Tchounwou, P. B. (2015)., Genotoxicity study of silver nanoparticles in bone marrow cells of sprague-dawley rats., Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 85, 52-60. doi:10.1016/j.fct.2015.05.005 [doi]
    Davis JP, Koyanagi M, Maronpot RR, Recio L, Hayashi SM., Identification of compound causing yellow bone discoloration following alpha-glycosyl isoquercitrin exposure in Sprague-Dawley rats, Arch Toxicol. 2020 Jul;94(7):2413-2421. doi: 10.1007/s00204-020-02760-z. Epub 2020 May 9.
    Frawley, R. P., Smith, M., Cesta, M. F., Hayes-Bouknight, S., Blystone, C., Kissling, G. E., . . . Germolec, D. (2018)., Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female harlan sprague-dawley rats and B6C3F1/N mice when administered by oral gavage for 28 days, Journal of Immunotoxicology, 15(1), 41-52. doi:10.1080/1547691X.2018.1445145 [doi]
    Stein, A., Kraus, D. W., Doeller, J. E., & Bailey, S. M. (2015), Inhalation exposure model of hydrogen sulfide (H(2)S)-induced hypometabolism in the male sprague-dawley rat., Methods in Enzymology, 555, 19-35. doi:10.1016/bs.mie.2014.11.019 [doi]
    Roberts SM, Rohr AC, Mikheev VB, Munson J, Sabo-Attwood T., Influence of airborne particulates on respiratory tract deposition of inhaled toluene and naphthalene in the rat, Inhal Toxicol. 2018 Jan;30(1):19-28. doi: 10.1080/08958378.2018.1438539. Epub 2018 Feb 21.
    Gallardo-Toledo E, Tapia-Arellano A, Celis F, Sinai T, Campos M, Kogan MJ, Sintov AC., Intranasal administration of gold nanoparticles designed to target the central nervous system: Fabrication and comparison between nanospheres and nanoprisms, Int J Pharm. 2020 Nov 30;590:119957. doi: 10.1016/j.ijpharm.2020.119957. Epub 2020 Oct 6.
    Waterhouse, D. N., Sutherland, B. W., Santos, N. D., Masin, D., Osooly, M., Strutt, D., . . . Webb, M. S. (2014), Irinophore C, a lipid nanoparticle formulation of irinotecan, abrogates the gastrointestinal effects of irinotecan in a rat model of clinical toxicities, Investigational New Drugs, 32(6), 1071-1082. doi:10.1007/s10637-014-0138-x [doi]
    Ackerman, Z., Pappo, O., Link, G., Glazer, M., & Grozovski, M. (2015)., Liver toxicity of thioacetamide is increased by hepatocellular iron overload., Biological Trace Element Research, 163(1-2), 169-176. doi:10.1007/s12011-014-0110-9 [doi]
    Filgo, A. J., Foley, J. F., Puvanesarajah, S., Borde, A. R., Midkiff, B. R., Reed, C. E., . . . Fenton, S. E. (2016)., Mammary gland evaluation in juvenile toxicity studies: Temporal developmental patterns in the male and female harlan sprague-dawley rat., Toxicologic Pathology, 44(7), 1034-1058. doi:10.1177/0192623316663864 [doi]
    Mathews, J. M., Brown, S. S., Patel, P. R., Black, S. R., Banks, T. T., Etheridge, A. S., . . . Waidyanatha, S. (2013)., Metabolism and disposition of [14C]n-butyl-p-hydroxybenzoate in male and female harlan sprague dawley rats following oral administration and dermal application., Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 43(2), 169-181. doi:10.3109/00498254.2012.702935 [doi]
    Lacy, S., Hsu, B., Miles, D., Aftab, D., Wang, R., & Nguyen, L. (2015), Metabolism and disposition of cabozantinib in healthy male volunteers and pharmacologic characterization of its major metabolites., Drug Metabolism and Disposition: The Biological Fate of Chemicals, 43(8), 1190-1207. doi:10.1124/dmd.115.063610 [doi]
    Schwartz-Zimmermann, Heidi E; Binder, Sabina B; Hametner, Christian; Miró-Abella, Eugènia; Schwarz, Christiane; Michlmayr, Herbert; Reiterer, Nicole; Labudova, Silvia; Adam, Gerhard; Berthiller, Franz;, Metabolism of nivalenol and nivalenol-3-glucoside in rats, Toxicology letters Vol.306, 2019
    Nyska, A., Hayashi, S. M., Koyanagi, M., Davis, J. P., Jokinen, M. P., Ramot, Y., & Maronpot, R. R. (2016)., Ninety-day toxicity and single-dose toxicokinetics study of alpha-glycosyl isoquercitrin in sprague-dawley rats., Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 97, 354-366. doi:S0278-6915(16)30346-5 [pii]
    Sutherland, Jessica E; Hettinger, Julia L; Chan, Amy; Gilbert, Jason; Warner, Garvin L; Davis, Wendell P;, Nonclinical Safety Profile of Revusiran, a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis., Nucleic acid therapeutics Vol.306, 2019
    National Toxicology Program., NTP Developmental and Reproductive Toxicity Technical Report on the Prenatal Development Studies of 4-Methylcyclohexanemethanol (CASRN 34885-03-5) in Sprague Dawley (Hsd:Sprague Dawley(ÂŽ) SD(ÂŽ)) Rats (Gavage Studies): DART Report 02, Research Triangle Park (NC): National Toxicology Program; 2020 Jun.
    Zimmer DP, Shea CM, Tobin JV, Tchernychev B, Germano P, Sykes K, Banijamali AR, Jacobson S, Bernier SG, Sarno R, Carvalho A, Chien YT, Graul R, Buys ES, Jones JE, Wakefield JD, Price GM, Chickering JG, Milne GT, Currie MG, Masferrer JL., Olinciguat, an Oral sGC Stimulator, Exhibits Diverse Pharmacology Across Preclinical Models of Cardiovascular, Metabolic, Renal, and Inflammatory Disease, Front Pharmacol. 2020 Apr 8;11:419. doi: 10.3389/fphar.2020.00419. eCollection 2020.
    Huang MC, Furr JR, Robinson VG, Betz L, Shockley K, Cunny H, Witt K, Waidyanatha S, Germolec D., Oral deoxynivalenol toxicity in Harlan Sprague Dawley (Hsd:Sprague DawleyÂŽ SDÂŽ) rat dams and their offspring, Food Chem Toxicol. 2020 Dec 31;148:111963. doi: 10.1016/j.fct.2020.111963. Online ahead of print.
    Wangpradit, O., Adamcakova-Dodd, A., Heitz, K., Robertson, L., Thorne, P. S., & Luthe, G. (2016), PAMAM dendrimers as nano carriers to investigate inflammatory responses induced by pulmonary exposure of PCB metabolites in sprague-dawley rats., Environmental Science and Pollution Research International, 23(3), 2128-2137. doi:10.1007/s11356-015-5022-5 [doi]
    Truver MT, Smith CR, Garibay N, Kopajtic TA, Swortwood MJ, Baumann MH., Pharmacodynamics and pharmacokinetics of the novel synthetic opioid, U-47700, in male rats, Neuropharmacology. 2020 Oct 15;177:108195. doi: 10.1016/j.neuropharm.2020.108195. Epub 2020 Jun 10.
    Watson ATD, Sutherland VL, Cunny H, Miller-Pinsler L, Furr J, Hebert C, Collins B, Waidyanatha S, Smith L, Vinke T, Aillon K, Xie G, Shockley KR, McIntyre BS., Postnatal Effects of Gestational and Lactational Gavage Exposure to Boric Acid in the Developing Sprague Dawley Rat, Toxicol Sci. 2020 Jul 1;176(1):65-73. doi: 10.1093/toxsci/kfaa061.
    Berthold EC, Kamble SH, Raju KS, King TI, Popa R, Sharma A, LeĂłn F, Avery BA, McMahon LR, McCurdy CR., Preclinical pharmacokinetic study of speciociliatine, a kratom alkaloid, in rats using an UPLC-MS/MS method, J Pharm Biomed Anal. 2021 Feb 5;194:113778. doi: 10.1016/j.jpba.2020.113778. Epub 2020 Nov 21.
    Carreiro, S., Blum, J., & Hack, J. B. (2014)., Pretreatment with intravenous lipid emulsion reduces mortality from cocaine toxicity in a rat model., Annals of Emergency Medicine, 64(1), 32-37. doi:10.1016/j.annemergmed.2013.11.017 [doi]
    Silva, M. J., Hilton, D., Furr, J., Gray, L. E., Preau, J. L., Calafat, A. M., & Ye, X. (2015)., Quantification of tetrabromo benzoic acid and tetrabromo phthalic acid in rats exposed to the flame retardant uniplex FPR-45., Archives of Toxicology, doi:10.1007/s00204-015-1489-6 [doi]
    Simmons JK, Burke PJ, Cochran JH, Pittman PG, Lyon RP., Reducing the antigen-independent toxicity of antibody-drug conjugates by minimizing their non-specific clearance through PEGylation, Toxicol Appl Pharmacol. 2020 Apr 1;392:114932. doi: 10.1016/j.taap.2020.114932. Epub 2020 Feb 25.
    Shen, H., Robertson, L. W., & Ludewig, G. (2012)., Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male sprague dawley rats., Toxicology Letters, 209(3), 291-298. doi:10.1016/j.toxlet.2012.01.003 [doi]
    Jonsson, M., Atosuo, J., Jestoi, M., Nathanail, A. V., Kokkonen, U. M., Anttila, M., . . . Peltonen, K. (2015)., Repeated dose 28-day oral toxicity study of moniliformin in rats, Toxicology Letters, 233(1), 38-44. doi:10.1016/j.toxlet.2014.11.006 [doi]
    Hooth, M. J., Nyska, A., Fomby, L. M., Vasconcelos, D. Y., Vallant, M., DeVito, M. J., & Walker, N. J. (2012), Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female harlan sprague-dawley rats., Toxicology, 301(1-3), 85-93. doi:10.1016/j.tox.2012.07.005 [doi]
    Maranghi, F., De Angelis, S., Tassinari, R., Chiarotti, F., Lorenzetti, S., Moracci, G., . . . Olivieri, A. (2013)., Reproductive toxicity and thyroid effects in sprague dawley rats exposed to low doses of ethylenethiourea., Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 59, 261-271. doi:10.1016/j.fct.2013.05.048 [doi]
    Chrusciel, Paulina; Yatkin, Emrah; Li, Xiang-Guo; Jaakkola, Ulla-Marjut; Knuuti, Juhani; Jalkanen, Sirpa; Roivainen, Anne;, Safety Study of Single-Dose Intravenously Administered DOTA-Siglec-9 Peptide in Sprague Dawley Rats., International journal of toxicology Vol.38,
    Patlolla, A. K., Hackett, D., & Tchounwou, P. B. (2015)., Silver nanoparticle-induced oxidative stress-dependent toxicity in sprague-dawley rats., Molecular and Cellular Biochemistry, 399(1-2), 257-268. doi:10.1007/s11010-014-2252-7 [doi]
    Patlolla, A. K., Hackett, D., & Tchounwou, P. B. (2015), Silver nanoparticle-induced oxidative stress-dependent toxicity in sprague-dawley rats., Molecular and Cellular Biochemistry, 399(1-2), 257-268. doi:10.1007/s11010-014-2252-7 [doi]
    Mutlu, E., Pierfelice, J., McIntyre, B. S., Cunny, H. C., Kissling, G. E., Burback, B., & Waidyanatha, S. (2017)., Simultaneous quantitation of 2-hydroxy-4-methoxybenzophenone, a sunscreen ingredient, and its metabolites in harlan sprague dawley rat plasma following perinatal dietary exposure., Journal of Analytical Toxicology, 41(9), 744-754. doi:10.1093/jat/bkx070 [doi]
    Zhang N, Sarkar AK, Li F, Demerzhan SA, Gilbertson SR, Pati D., Stability and pharmacokinetics of separase inhibitor-Sepin-1 in Sprague-Dawley rats, Biochem Pharmacol. 2020 Apr;174:113808. doi: 10.1016/j.bcp.2020.113808. Epub 2020 Jan 10.
    Aqil, F., Shen, H., Jeyabalan, J., Xin, X., Lehmler, H. J., Ludewig, G., . . . Gupta, R. C. (2014)., Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants., Toxicology Reports, 1, 820-833. doi:10.1016/j.toxrep.2014.09.010 [doi]
    Cannon, Ronald E; Trexler, Andrew W; Knudsen, Gabriel A; Evans, Rebecca A; Birnbaum, Linda S;, Tetrabromobisphenol A (TBBPA) Alters ABC Transport at the Blood-Brain Barrier., Toxicological sciences : an official journal of the Society of Toxicology Vol.169, 2019
    Lasrado, J. A., Trinker, D., Ceddia, M. A., & Herrlinger, K. A. (2015)., The safety of a dry spearmint extract in vitro and in vivo., Regulatory Toxicology and Pharmacology : RTP, 71(2), 213-224. doi:10.1016/j.yrtph.2014.12.007 [doi]
    Zhang N, Sarkar AK, Pati D., Toxicity study of separase inhibitor-Sepin-1 in Sprague-Dawley rats, Pathol Res Pract. 2020 Jan;216(1):152730. doi: 10.1016/j.prp.2019.152730. Epub 2019 Nov 11.
    Waidyanatha, Suramya; Black, Sherry R; Aillon, Kristin; Collins, Brad; Patel, Purvi R; Riordan, Felicia; Sutherland, Vicki; Robinson, Veronica Godfrey; Fernando, Reshan; Fennell, Timothy R;, Toxicokinetics and bioavailability of bisphenol AF following oral administration in rodents: A dose, species, and sex comparison., Toxicology and applied pharmacology Vol.373, 2019
    Waidyanatha, Suramya; Black, Sherry R; Fennell, Timothy R; Watson, Scott L; Patel, Purvi R; Cooper, Stephen D; Blake, James; Robinson, Veronica Godfrey; Fernando, Reshan A; Blystone, Chad R;, Toxicokinetics and bioavailability of sulfolane, a ground water contaminant, following oral and intravenous administration in rodents: A dose, species, and sex comparison., Toxicology and applied pharmacology Vol.379, 2019
    Huang, M C; Dzierlenga, A L; Robinson, V G; Waidyanatha, S; DeVito, M J; Eifrid, M A; Granville, C A; Gibbs, S T; Blystone, C R;, Toxicokinetics of perfluorobutane sulfonate (PFBS), perfluorohexane-1-sulphonic acid (PFHxS), and perfluorooctane sulfonic acid (PFOS) in male and female Hsd:Sprague Dawley SD rats after intravenous and gavage administration., Toxicology reports Vol.6, 2019
    Dzierlenga, Anika L; Robinson, Veronica G; Waidyanatha, Suramya; DeVito, Michael J; Eifrid, Max A; Gibbs, Seth T; Granville, Courtney A; Blystone, Chad R;, Toxicokinetics of perfluorohexanoic acid (PFHxA), perfluorooctanoic acid (PFOA) and perfluorodecanoic acid (PFDA) in male and female Hsd:Sprague dawley SD rats following intravenous or gavage administration, Xenobiotica; the fate of foreign compounds in biological systems Vol.38, 2019
    Lucarini E, Trallori E, Tomassoni D, Amenta F, Ghelardini C, Pacini A, Di Cesare Mannelli L., Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms, Antioxidants (Basel). 2020 Aug 14;9(8):749. doi: 10.3390/antiox9080749.
    Guevarra, C. S., Borke, J. L., Stevens, M. R., Bisch, F. C., Zakhary, I., Messer, R., . . . Elsalanty, M. E. (2015)., Vascular alterations in the sprague-dawley rat mandible during intravenous bisphosphonate therapy., The Journal of Oral Implantology, 41(2), e24-9. doi:10.1563/AAID-JOI-D-13-00074 [doi]
    Watson ATD, Johnson VJ, Luster MI, Burleson GR, Fallacara DM, Sparrow BR, Cesta MF, Cora MC, Shockley KR, Stout MD, Blystone CR, Germolec DR., Immunotoxicity studies of sulfolane following developmental exposure in Hsd:Sprague Dawley SD rats and adult exposure in B6C3F1/N mice, J Immunotoxicol. 2021 Dec;18(1):1-12. doi: 10.1080/1547691X.2020.1869355.
    Carrillo JC, Shen H, Momin F, Kral O, Schnieder H, Kühn S., GTL synthetic paraffin oil shows low liver and tissue retention compared to mineral oil, Food Chem Toxicol. 2021 Nov 25:112701. doi: 10.1016/j.fct.2021.112701. Online ahead of print.
    Ibrahim R, Nyska A, Dunnick J, Ramot Y., The toxicologic pathology aspects of selected natural herbal products and related compounds, J Toxicol Pathol. 2021 Jul;34(3):181-211. doi: 10.1293/tox.2021-0016. Epub 2021 Mar 29.
    VanEtten SL, Bonner MR, Ren X, Birnbaum LS, Kostyniak PJ, Wang J, Olson JR., Effect of exposure to 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and polychlorinated biphenyls (PCBs) on mitochondrial DNA (mtDNA) copy number in rats, Toxicology. 2021 Apr 30;454:152744. doi: 10.1016/j.tox.2021.152744. Epub 2021 Mar 4.
    Hoffman JF, Vergara VB, Fan AX, Kalinich JF., Effect of embedded metal fragments on urinary metal levels and kidney biomarkers in the Sprague-Dawley rat, Toxicol Rep. 2021 Mar 1;8:463-480. doi: 10.1016/j.toxrep.2021.02.023. eCollection 2021.
    Huang MC, Furr JR, Robinson VG, Betz L, Shockley K, Cunny H, Witt K, Waidyanatha S, Germolec D., Oral deoxynivalenol toxicity in Harlan Sprague Dawley (Hsd:Sprague DawleyŽ SDŽ) rat dams and their offspring, Food Chem Toxicol. 2021 Feb;148:111963. doi: 10.1016/j.fct.2020.111963. Epub 2020 Dec 31.
    Moquist PN, Bovee TD, Waight AB, Mitchell JA, Miyamoto JB, Mason ML, Emmerton KK, Stevens N, Balasubramanian C, Simmons JK, Lyon RP, Senter PD, Doronina SO., Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux-positive Tumor Models, Mol Cancer Ther. 2021 Feb;20(2):320-328. doi: 10.1158/1535-7163.MCT-20-0618. Epub 2020 Dec 7.
    Lyski RD, Bou LB, Lau UY, Meyer DW, Cochran JH, Okeley NM, Emmerton KK, Zapata F, Simmons JK, Trueblood ES, Ortiz DJ, Zaval MC, Snead KM, Jin S, Farr LM, Ryan MC, Senter PD, Jeffrey SC., Development of Novel Antibody-Camptothecin Conjugates, Mol Cancer Ther. 2021 Feb;20(2):329-339. doi: 10.1158/1535-7163.MCT-20-0526. Epub 2020 Dec 3.
    Waidyanatha S, Collins BJ, Cunny H, Aillon K, Riordan F, Turner K, McBride S, Betz L, Sutherland V., An investigation of systemic exposure to bisphenol AF during critical periods of development in the rat, Toxicol Appl Pharmacol. 2021 Jan 15;411:115369. doi: 10.1016/j.taap.2020.115369. Epub 2020 Dec 15.
    Waidyanatha S, Mutlu E, Gibbs S, Pierfelice J, Smith JP, Burback B, Blystone CT., Phenolic benzotriazoles: a class comparison of toxicokinetics of ultraviolet-light absorbers in male rats., Xenobiotica. 2021 Jul;51(7):831-841. doi: 10.1080/00498254.2021.1927239. Epub 2021 May 24.
    Walton SE, Krotulski AJ, Glatfelter GC, Walther D, Logan BK, Baumann MH., Plasma pharmacokinetics and pharmacodynamic effects of the 2-benzylbenzimidazole synthetic opioid, isotonitazene, in male rats, Psychopharmacology (Berl). 2023 Jan;240(1):185-198. doi: 10.1007/s00213-022-06292-5. Epub 2022 Dec 17.
    Witchey SK, Sutherland V, Collins B, Roberts G, Shockley KR, Vallant M, Krause J, Cunny H, Waidyanatha S, Mylchreest E, Sparrow B, Moyer R, Behl M., Reproductive and developmental toxicity following exposure to organophosphate ester flame retardants and plasticizers, triphenyl phosphate and isopropylated phenyl phosphate, in Sprague Dawley rats, Toxicol Sci. 2022 Dec 23:kfac135. doi: 10.1093/toxsci/kfac135. Online ahead of print.
    Auerbach SS, Behl MV, Collins BJ, Cora MC, Fostel JM, Liu YF, Luh J, Roberts GK, Shipkowski KA, Waidyanatha S, Watson ATD., NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Tricresyl Phosphate (CASRN 1330-78-5) in Male Sprague Dawley (Hsd:Sprague Dawley(®) SD(®)) Rats (Gavage Studies): NIEHS Report 06, Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2022 Oct.
    Auerbach SS, Behl MV, Collins BJ, Cora MC, Fostel JM, Ingle BL, Liu YF, Luh J, Roberts GK, Shipkowski KA, Waidyanatha S, Watson ATD., NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of Isodecyl Diphenyl Phosphate (CASRN 29761-21-5) in Male Sprague Dawley (Hsd:Sprague Dawley(®) SD(®)) Rats (Gavage Studies): NIEHS Report 04, Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2022 Oct.
    Auerbach SS, Behl MV, Collins BJ, Cora MC, Fostel JM, Ingle BL, Liu YF, Luh J, Roberts GK, Shipkowski KA, Waidyanatha S, Watson ATD., NIEHS Report on the In Vivo Repeat Dose Biological Potency Study of tert-Butylphenyl Diphenyl Phosphate (CASRN 56803-37-3) in Male Sprague Dawley (Hsd:Sprague Dawley(®) SD(®)) Rats (Gavage Studies): NIEHS Report 03, Research Triangle Park (NC): National Institute of Environmental Health Sciences; 2022 Oct.
    Ramot Y, Dolkart O, Steiner M, Jahn S, Goldberg R, Cacical O, Lavie Y, Ezov N, Agar G, Nyska A., Preclinical In Vivo Safety of Poly-Phosphorylated Superlubrication Vectors for the Treatment of Osteoarthritis, Toxicol Pathol. 2022 Aug;50(6):787-792. doi: 10.1177/01926233221105393. Epub 2022 Jun 21.
    Vandeputte MM, Krotulski AJ, Walther D, Glatfelter GC, Papsun D, Walton SE, Logan BK, Baumann MH, Stove CP., Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole 'nitazene' synthetic opioid, Arch Toxicol. 2022 Jun;96(6):1845-1863. doi: 10.1007/s00204-022-03276-4. Epub 2022 Apr 28.
    Sangaraju D, Katavolos P, Liang X, Chou C, Zabka TS, Dean B, Maher J., Establishment of baseline profiles of 50 bile acids in preclinical toxicity species: A comprehensive assessment of translational differences and study design considerations for biomarker development, Toxicol Appl Pharmacol. 2022 May 15;443:116008. doi: 10.1016/j.taap.2022.116008. Epub 2022 Apr 1.
    Waidyanatha S, Weber FX, Fallacara DM, Harrington JM, Levine K, Robinson VG, Sparrow BR, Stout MD, Fernando R, Hooth MJ, Xie G, Roberts GK., Systemic exposure and urinary excretion of vanadium following perinatal subchronic exposure to vanadyl sulfate and sodium metavanadate via drinking water, Toxicol Lett. 2022 May 1;360:53-61. doi: 10.1016/j.toxlet.2022.03.004. Epub 2022 Mar 21.
    Villani P, Eleuteri P, Pacchierotti F, Maranghi F, Tassinari R, Narciso L, Tait S, Lori G, Andreoli C, Huet S, Jarry G, Fessard V, Cordelli E., Pyrogenic synthetic amorphous silica (NM-203): Genotoxicity in rats following sub-chronic oral exposure, Mutat Res Genet Toxicol Environ Mutagen. 2022 Apr-May;876-877:503458. doi: 10.1016/j.mrgentox.2022.503458. Epub 2022 Jan 24.
    Fuller JC Jr, Rathmacher JA., Acute dose toxicity evaluation of the food supplement calcium 3-hydroxy-3-methylbutyrate (HMB) in female Sprague Dawley rats, Regul Toxicol Pharmacol. 2022 Apr;130:105133. doi: 10.1016/j.yrtph.2022.105133. Epub 2022 Feb 2.
    Collins B, Slade D, Aillon K, Stout M, Betz L, Waidyanatha S, Ryan K., Plasma concentrations of tris(1-chloro-2-propyl) phosphate and a metabolite bis(2-chloroisopropyl) 1-carboxyethyl phosphate in Sprague-Dawley rats and B6C3F1/N mice from a chronic study of tris(chloropropyl) phosphate via feed, Toxicol Rep. 2022 Mar 29;9:690-698. doi: 10.1016/j.toxrep.2022.03.025. eCollection 2022.
    Wang H, Adamcakova-Dodd A, Lehmler HJ, Hornbuckle KC, Thorne PS., Toxicity Assessment of 91-Day Repeated Inhalation Exposure to an Indoor School Air Mixture of PCBs, Environ Sci Technol. 2022 Feb 1;56(3):1780-1790. doi: 10.1021/acs.est.1c05084. Epub 2022 Jan 7.
    Walker SM, Malkmus S, Eddinger K, Steinauer J, Roberts AJ, Shubayev VI, Grafe MR, Powell SB, Yaksh TL., Evaluation of neurotoxicity and long-term function and behavior following intrathecal 1 % 2-chloroprocaine in juvenile rats, Neurotoxicology. 2022 Jan;88:155-167. doi: 10.1016/j.neuro.2021.11.010. Epub 2021 Nov 18.
    Leber A, Hontecillas R, Zoccoli-Rodriguez V, Ehrich M, Chauhan J, Bassaganya-Riera J., Exploratory studies with NX-13: oral toxicity and pharmacokinetics in rodents of an orally active, gut-restricted first-in-class therapeutic for IBD that targets NLRX1, Drug Chem Toxicol. 2022 Jan;45(1):209-214. doi: 10.1080/01480545.2019.1679828. Epub 2019 Oct 25.

    Tumor biology

    Hyppönen V, Stenroos P, Nivajärvi R, Ardenkjaer-Larsen JH, Gröhn O, Paasonen J, Kettunen MI., Metabolism of hyperpolarised [1-(13) C]pyruvate in awake and anaesthetised rat brains, NMR Biomed. 2021 Oct 21:e4635. doi: 10.1002/nbm.4635. Online ahead of print.

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