Teratology
- Aging
- General studies
- Nutrition
- Oncology
- Other
- Preclinical (PK/PD)
- Surgical
- Teratology
- Toxicology
Aging
Krug A, Wöhr M, Seffer D, Rippberger H, Sungur A Ö, Dietsche B, Stein F, Sivalingam S, Forstner AJ, Witt SH, Dukal H, Streit F, Maaser A, Heilmann-Heimbach S, Andlauer TFM, Herms S, Hoffmann P, Rietschel M, Nöthen MM, Lackinger M, Schratt G, Koch M, Schwarting RKW, Kircher T., Advanced paternal age as a risk factor for neurodevelopmental disorders: a translational study, Mol Autism. 2020 Jun 23;11(1):54. doi: 10.1186/s13229-020-00345-2.
Marshall, Hayley J; Pezze, Marie A; Fone, Kevin C F; Cassaday, Helen J;, Age-related differences in appetitive trace conditioning and novel object recognition procedures., Neurobiology of learning and memory Vol.164, 2019
Cabiati M, Salvadori C, Sapio A, Burchielli S, Carlucci L, Moscato S, Sabatino L, Caselli C, Mattii L, Del Ry S., Aging and biomarkers: Transcriptional levels evaluation of Osteopontin/miRNA-181a axis in hepatic tissue of rats in different age ranges, Exp Gerontol. 2020 May;133:110879. doi: 10.1016/j.exger.2020.110879. Epub 2020 Feb 17.
Gull S, Gaser C, Herrmann KH, Urbach A, Boehme M, Afzal S, Reichenbach JR, Witte OW, Schmidt S., Brain Macro-Structural Alterations in Aging Rats: A Longitudinal Lifetime Approach., Cells. 2023 Jan 28;12(3). pii: 432. doi: 10.3390/cells12030432.
Aitken TJ, Crabtree JE, Jensen DM, Hess KH, Leininger BR, Tessem JS., Decreased proliferation of aged rat beta cells corresponds with enhanced expression of the cell cycle inhibitor p27(KIP1), Biol Cell. 2021 Dec;113(12):507-521. doi: 10.1111/boc.202100035. Epub 2021 Sep 27.
Rickard, R. F., Engelbrecht, G. H., & Hudson, D. A. (2011)., Experimental investigation of two techniques of arterial microanastomosis used to manage a small-to-large diameter discrepancy., Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS, 64(8), 1088-1095. doi:10.1016/j.bjps.2011.03.011 [doi]
Rickard, R. F., McPhaden, A. R., & Hudson, D. A. (2014), Healing of two microarterial anastomoses with diameter mismatch, The Journal of Surgical Research, 191(1), 239-49.e3. doi:10.1016/j.jss.2014.03.011 [doi]
Moscato S, Cabiati M, Bianchi F, Panetta D, Burchielli S, Massimetti G, Del Ry S, Mattii L., Heart and liver connexin expression related to the first stage of aging: A study on naturally aged animals, Acta Histochem. 2020 Dec;122(8):151651. doi: 10.1016/j.acthis.2020.151651. Epub 2020 Nov 7.
Pereira GC, Lee L, Rawlings N, Ouwendijk J, Parker JE, Andrienko TN, Henley JM, Halestrap AP., Hexokinase II dissociation alone cannot account for changes in heart mitochondrial function, morphology and sensitivity to permeability transition pore opening following ischemia, PLoS One. 2020 Jun 24;15(6):e0234653. doi: 10.1371/journal.pone.0234653. eCollection 2020.
Werkman IL, Kövilein J, de Jonge JC, Baron W., Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination, J Neurochem. 2020 Jun 30. doi: 10.1111/jnc.15113. Online ahead of print.
Anderton, M. J., Mellor, H. R., Bell, A., Sadler, C., Pass, M., Powell, S., . . . Heier, A. (2011)., Induction of heart valve lesions by small-molecule ALK5 inhibitors, Toxicologic Pathology, 39(6), 916-924. doi:10.1177/0192623311416259 [doi]
Macdonald, D., Tessari, M. A., Boogaard, I., Smith, M., Pulli, K., Szynol, A., . . . Munoz-Sanjuan, I. (2014)., Quantification assays for total and polyglutamine-expanded huntingtin proteins., PloS One, 9(5), e96854. doi:10.1371/journal.pone.0096854 [doi]
P Graf A, Hansson AC, Spanagel R., Isolated during adolescence: long-term impact on social behavior, pain sensitivity, and the oxytocin system in male and female rats, Biol Sex Differ. 2024 Oct 15;15(1):78. doi: 10.1186/s13293-024-00655-7.
General studies
Campbell BFN, Dittmann A, Dreier B, Plückthun A, Tyagarajan SK., A DARPin-based molecular toolset to probe gephyrin and inhibitory synapse biology, Elife. 2022 Oct 31;11:e80895. doi: 10.7554/eLife.80895.
Jernigan NL, Naik JS, Resta TC., Acid-sensing ion channel 1 contributes to pulmonary arterial smooth muscle cell depolarization following hypoxic pulmonary hypertension., J Physiol. 2021 Nov;599(21):4749-4762. doi: 10.1113/JP282231. Epub 2021 Sep 25.
Kalafateli, Aimilia Lydia; VallĂśf, Daniel; Jerlhag, Elisabet;, Activation of amylin receptors attenuates alcohol-mediated behaviours in rodents, Addiction biology Vol.24, 2019
Vestlund J, Bergquist F, Licheri V, Adermark L, Jerlhag E., Activation of glucagon-like peptide-1 receptors and skilled reach foraging, Addict Biol. 2021 May;26(3):e12953. doi: 10.1111/adb.12953. Epub 2020 Aug 8.
Sousa Fialho MDL, Purnama U, Dennis KMJH, Montes Aparicio CN, Castro-Guarda M, Massourides E, Tyler DJ, Carr CA, Heather LC., Activation of HIF1 Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart., Diabetes. 2021 Nov;70(11):2518-2531. doi: 10.2337/db21-0398. Epub 2021 Sep 15.
Lundberg, Stina; Högman, Cecilia; Roman, Erika;, Adolescent Exploratory Strategies and Behavioral Types in the Multivariate Concentric Square FieldTM Test., Frontiers in behavioral neuroscience Vol.13, 2019
Schneider, P., Bindila, L., Schmahl, C., Bohus, M., Meyer-Lindenberg, A., Lutz, B., . . . Schneider, M. (2016), Adverse social experiences in adolescent rats result in enduring effects on social competence, pain sensitivity and endocannabinoid signaling., Frontiers in Behavioral Neuroscience, 10, 203. doi:10.3389/fnbeh.2016.00203 [doi]
Joekel DE, Nur S, Monné Rodriguez J, Kronenberg PA, Kipar A, LeibundGut-Landmann S, Deplazes P., Agranulocytosis leads to intestinal Echinococcus multilocularis oncosphere invasion and hepatic metacestode development in naturally resistant Wistar rats, Parasitology. 2021 Jan;148(1):53-62. doi: 10.1017/S0031182020002012. Epub 2020 Oct 22.
Grotell M, den Hollander B, Jalkanen A, Törrönen E, Ihalainen J, de Miguel E, Dudek M, Kettunen MI, Hyytiä P, Forsberg MM, Kankuri E, Korpi ER., Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity, Front Pharmacol. 2021 Apr 28;12:679759. doi: 10.3389/fphar.2021.679759. eCollection 2021.
Leroux G, Neumann M, Meunier CF, Voisin V, Habsch I, Caron N, Michiels C, Wang L, Su BL., Alginate@TiO(2) hybrid microcapsules with high in vivo biocompatibility and stability for cell therapy, Colloids Surf B Biointerfaces. 2021 Jul;203:111770. doi: 10.1016/j.colsurfb.2021.111770. Epub 2021 Apr 16.
Juschten J, Ingelse SA, Bos LDJ, Girbes ARJ, Juffermans NP, van der Poll T, Schultz MJ, Tuinman PR; BASIC study investigators., Alkaline phosphatase in pulmonary inflammation-a translational study in ventilated critically ill patients and rats, Intensive Care Med Exp. 2020 Dec 18;8(Suppl 1):46. doi: 10.1186/s40635-020-00335-x.
Ruiz-Iglesias P, Estruel-Amades S, Camps-Bossacoma M, Massot-Cladera M, Castell M, Pérez-Cano FJ., Alterations in the mucosal immune system by a chronic exhausting exercise in Wistar rats, Sci Rep. 2020 Oct 21;10(1):17950. doi: 10.1038/s41598-020-74837-9.
Sanada TJ, Sun XQ, Happé C, Guignabert C, Tu L, Schalij I, Bogaard HJ, Goumans MJ, Kurakula K., Altered TGF?/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention, Cells. 2021 Jan 6;10(1):84. doi: 10.3390/cells10010084.
Loftén A, Adermark L, Ericson M, Söderpalm B., An acetylcholine-dopamine interaction in the nucleus accumbens and its involvement in ethanol's dopamine-releasing effect, Addict Biol. 2020 Aug 13:e12959. doi: 10.1111/adb.12959. Online ahead of print.
Kalafateli, Aimilia Lydia; Vallöf, Daniel; Colombo, Giancarlo; Lorrai, Irene; Maccioni, Paola; Jerlhag, Elisabet;, An amylin analogue attenuates alcohol-related behaviours in various animal models of alcohol use disorder. Neuropsychopharmacology, official publication of the American College of Neuropsychopharmacology Vol.44, 2019
Kalafateli AL, Satir TM, Vallöf D, Zetterberg H, Jerlhag E., An amylin and calcitonin receptor agonist modulates alcohol behaviors by acting on reward-related areas in the brain, Prog Neurobiol. 2021 May;200:101969. doi: 10.1016/j.pneurobio.2020.101969. Epub 2020 Dec 2.
Nikam SP, Nettleton K, Everitt JI, Barton HA, Becker ML., Antibiotic eluting poly(ester urea) films for control of a model cardiac implantable electronic device infection, Acta Biomater. 2020 Jul 15;111:65-79. doi: 10.1016/j.actbio.2020.04.025. Epub 2020 May 22.
Juschten, Jenny; Ingelse, Sarah Anne; Maas, Martinus Adrianus Wilhelmus; Girbes, Armand Roelof Johan; Juffermans, Nicole Petra; Schultz, Marcus Josephus; Tuinman, Pieter Roel;, Antithrombin plus alpha-1 protease inhibitor does not affect coagulation and inflammation in two murine models of acute lung injury., Intensive care medicine experimental Vol.7, 2019
Tukker AM, Wijnolts FMJ, de Groot A, Westerink RHS., Applicability of hiPSC-Derived Neuronal Cocultures and Rodent Primary Cortical Cultures for In Vitro Seizure Liability Assessment, Toxicol Sci. 2020 Nov 1;178(1):71-87. doi: 10.1093/toxsci/kfaa136.
Le Page LM, Rider OJ, Lewis AJ, Noden V, Kerr M, Giles L, Ambrose LJA, Ball V, Mansor L, Heather LC, Tyler DJ., Assessing the effect of hypoxia on cardiac metabolism using hyperpolarized (13) C magnetic resonance spectroscopy, NMR Biomed. 2019 Jul;32(7):e4099. doi: 10.1002/nbm.4099. Epub 2019 May 15.
Adermark L, Lagstram O, et al., Astrocytes modulate extracellular neurotransmitter levels and excitatory neurotransmission in dorsolateral striatum via dopamine D2 receptor signaling., Neuropsychopharmacology. 2021 Nov 22. doi: 10.1038/s41386-021-01232-x. [Epub ahead of print]
Callahan PM, Plagenhoef MR, Blake DT, Terry AV Jr., Atomoxetine improves memory and other components of executive function in young-adult rats and aged rhesus monkeys, Neuropharmacology. 2019 Sep 1;155:65-75. doi: 10.1016/j.neuropharm.2019.05.016. Epub 2019 May 18.
Sherman, D., Oram, T., Harel, D., & Ahissar, E. (2017)., Attention robustly gates a closed-loop touch reflex, Current Biology : CB, 27(12), 1836-1843.e7. doi:S0960-9822(17)30624-3 [pii]
Goepfrich, A. A., Gluch, C., Friemel, C. M., & Schneider, M. (2013)., Behavioral differences in three wistar han rat lines for emotional reactivity, cognitive processing and ethanol intake., Physiology & Behavior, 110-111, 102-108. doi:10.1016/j.physbeh.2012.12.019 [doi]
Lundberg S, Roman E, Bell RL., Behavioral Profiles of Adolescent Alcohol-Preferring/Non-preferring (P/NP) and High/Low Alcohol-Drinking (HAD/LAD) Rats Are Dependent on Line but Not Sex, Front Neurosci. 2022 Jan 13;15:811401. doi: 10.3389/fnins.2021.811401. eCollection 2021.
Parafati, M., Lascala, A., Morittu, V. M., Trimboli, F., Rizzuto, A., Brunelli, E., . . . Janda, E. (2015), Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome., The Journal of Nutritional Biochemistry, 26(9), 938-948. doi:10.1016/j.jnutbio.2015.03.008 [doi]
Brancato A, Castelli V, Lavanco G, Tringali G, Micale V, Kuchar M, D'Amico C, Pizzolanti G, Feo S, Cannizzaro C., Binge-like Alcohol Exposure in Adolescence: Behavioural, Neuroendocrine and Molecular Evidence of Abnormal Neuroplasticity and Return., Biomedicines. 2021 Sep 4;9(9). pii: 1161. doi: 10.3390/biomedicines9091161.
Lee SJ, Krieger JP, Vergara M, Quinn D, McDougle M, de Araujo A, Darling R, Zollinger B, Anderson S, Pan A, Simonnet EJ, Pignalosa A, Arnold M, Singh A, Langhans W, Raybould HE, de Lartigue G., Blunted Vagal Cocaine- and Amphetamine-Regulated Transcript Promotes Hyperphagia and Weight Gain, Cell Rep. 2020 Feb 11;30(6):2028-2039.e4. doi: 10.1016/j.celrep.2020.01.045.
Vallöf , Daniel; Kalafateli, Aimilia Lydia; Jerlhag, Elisabet;, Brain region specific glucagon-like peptide-1 receptors regulate alcohol-induced behaviors in rodents, Psychoneuroendocrinology Vol.103, 2019
Bhatta P, Dhukhwa A, Sheehan K, Al Aameri RFH, Borse V, Ghosh S, Sheth S, Mamillapalli C, Rybak L, Ramkumar V, Mukherjea D., Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea, Sci Rep. 2019 Mar 11;9(1):4131. doi: 10.1038/s41598-019-40425-9.
Vallof, D., Ulenius, L., Egecioglu, E., Engel, J. A., & Jerlhag, E. (2017)., Central administration of the anorexigenic peptide neuromedin U decreases alcohol intake and attenuates alcohol-induced reward in rodents, Addiction Biology, 22(3), 640-651. doi:10.1111/adb.12355 [doi]
Barrios V, López-Villar E, Frago LM, Canelles S, Díaz-González F, Burgos-Ramos E, Frühbeck G, Chowen JA, Argente J., Cerebral Insulin Bolus Revokes the Changes in Hepatic Lipid Metabolism Induced by Chronic Central Leptin Infusion, Cells. 2021 Mar 6;10(3):581. doi: 10.3390/cells10030581.
Rickard, R. F., Wilson, J., & Hudson, D. A. (2009), Characterization of a rodent model for the study of arterial microanastomoses with size discrepancy (small-to-large), Laboratory Animals, 43(4), 350-356. doi:10.1258/la.2009.0080097 [doi]
AlMarabeh S, O'Neill J, Cavers J, Lucking EF, O'Halloran KD, Abdulla MH., Chronic intermittent hypoxia impairs diuretic and natriuretic responses to volume expansion in rats with preserved low-pressure baroreflex control of the kidney, Am J Physiol Renal Physiol. 2021 Jan 1;320(1):F1-F16. doi: 10.1152/ajprenal.00377.2020. Epub 2020 Nov 9.
Waeiss RA, Knight CP, Engleman EA, Hauser SR, Rodd ZA., Co-administration of ethanol and nicotine heightens sensitivity to ethanol reward within the nucleus accumbens (NAc) shell and increasing NAc shell BDNF is sufficient to enhance ethanol reward in naĂŻve Wistar rats, J Neurochem. 2020 Mar;152(5):556-569. doi: 10.1111/jnc.14914. Epub 2019 Dec 10.
Richards J, Miksys S, Novalen M, Tyndale RF., CYP2D in the brain impacts oral hydrocodone analgesia in vivo, Neuropharmacology. 2022 Dec 15;221:109291. doi: 10.1016/j.neuropharm.2022.109291. Epub 2022 Oct 12.
Somogyi G, Hlatky D, Spisák T, Spisák Z, Nyitrai G, Czurkó A., Deciphering the scopolamine challenge rat model by preclinical functional MRI, Sci Rep. 2021 May 25;11(1):10873. doi: 10.1038/s41598-021-90273-9.
Jackson-Cowan L, Eldahshan W, Dumanli S, Dong G, Jamil S, Abdul Y, Althomali W, Baban B, Fagan SC, Ergul A., Delayed Administration of Angiotensin Receptor (AT2R) Agonist C21 Improves Survival and Preserves Sensorimotor Outcomes in Female Diabetic Rats Post-Stroke through Modulation of Microglial Activation, Int J Mol Sci. 2021 Jan 29;22(3):1356. doi: 10.3390/ijms22031356.
Harris SB, Hardisty JF, Hayes AW, Weber K., Developmental and reproductive toxicity studies of BIA 10-2474, Regul Toxicol Pharmacol. 2020 Mar;111:104543. doi: 10.1016/j.yrtph.2019.104543. Epub 2019 Nov 20.
Vestin E, Lagström O, Domi A, Ericson M, Söderpalm B, Adermark L., Differential and long-lasting changes in neurotransmission in the amygdala of male Wistar rats during extended amphetamine abstinence, Neuropharmacology. 2022 Jun 1;210:109041. doi: 10.1016/j.neuropharm.2022.109041. Epub 2022 Mar 18.
Danielsson K, Stomberg R, Adermark L, Ericson M, Söderpalm B., Differential dopamine release by psychosis-generating and non-psychosis-generating addictive substances in the nucleus accumbens and dorsomedial striatum, Transl Psychiatry. 2021 Sep 13;11(1):472. doi: 10.1038/s41398-021-01589-z.
Callahan PM, Terry AV Jr, Peitsch MC, Hoeng J, Koshibu K., Differential effects of alkaloids on memory in rodents., Sci Rep. 2021 May 10;11(1):9843. doi: 10.1038/s41598-021-89245-w.
White AR, Werner CM, Holmes GM., Diminished enteric neuromuscular transmission in the distal colon following experimental spinal cord injury, Exp Neurol. 2020 Sep;331:113377. doi: 10.1016/j.expneurol.2020.113377. Epub 2020 Jun 8.
Salum, E., Kampus, P., Zilmer, M., Eha, J., Butlin, M., Avolio, A. P., . . . Kals, J. (2012)., Effect of vitamin D on aortic remodeling in streptozotocin-induced diabetes, Cardiovascular Diabetology, 11, 58-2840-11-58. doi:10.1186/1475-2840-11-58 [doi]
Kalafateli AL, Vestlund J, Raun K, Egecioglu E, Jerlhag E., Effects of a selective long-acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats, Addict Biol. 2020 May 8:e12910. doi: 10.1111/adb.12910. Online ahead of print.
Gines, I., Gil-Cardoso, K., Serrano, J., Casanova-Marti, A., Blay, M., Pinent, M., . . . Terra, X. (2018), Effects of an intermittent grape-seed proanthocyanidin (GSPE) treatment on a cafeteria diet obesogenic challenge in rats., Nutrients, 10(3), 10.3390/nu10030315. doi:E315 [pii]
Casarrubea M, Di Giovanni G, Crescimanno G., Effects of Different Anxiety Levels on the Behavioral Patternings Investigated through T-pattern Analysis in Wistar Rats Tested in the Hole-Board Apparatus, Brain Sci. 2021 May 27;11(6):714. doi: 10.3390/brainsci11060714.
Smethells JR, Greer A, Dougen B, Carroll ME., Effects of voluntary exercise and sex on multiply-triggered heroin reinstatement in male and female rats, Psychopharmacology (Berl). 2020 Feb;237(2):453-463. doi: 10.1007/s00213-019-05381-2. Epub 2019 Nov 11.
Reeves-Darby JA, Berro LF, Rowlett JK, Platt DM., Enhancement of cue-induced reinstatement of alcohol seeking by acute total sleep restriction in male Wistar rats., Pharmacol Biochem Behav. 2021 Jun;205:173188. doi: 10.1016/j.pbb.2021.173188. Epub 2021 Apr 9.
van der Wildt B, Nezam M, Kooijman EJM, Reyes ST, Shen B, Windhorst AD, Chin FT., Evaluation of carbon-11 labeled 5-(1-methyl-1H-pyrazol-4-yl)-N-(2-methyl-5-(3-(trifluoromethyl)benzamido)phenyl)nicotinamide as PET tracer for imaging of CSF-1R expression in the brain, Bioorg Med Chem. 2021 Jul 15;42:116245. doi: 10.1016/j.bmc.2021.116245. Epub 2021 May 30.
Rostami S, Xu M, Datta S, Haykal S., Evaluation of Early Markers of Ischemia-reperfusion Injury and Preservation Solutions in a Modified Hindlimb Model of Vascularized Composite Allotransplantation., Transplant Direct. 2021 Dec 13;8(1):e1251. doi: 10.1097/TXD.0000000000001251. eCollection 2022 Jan.
Fredriksson, I., Jayaram-Lindstrom, N., Wirf, M., Nylander, E., Nystrom, E., Jardemark, K., & Steensland, P. (2015), Evaluation of guanfacine as a potential medication for alcohol use disorder in long-term drinking rats: Behavioral and electrophysiological findings., Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 40(5), 1130-1140. doi:10.1038/npp.2014.294 [doi]
Paasonen E, Paasonen J, Lehto LJ, Pirttimäki T, Laakso H, Wu L, Ma J, Idiyatullin D, Tanila H, Mangia S, Michaeli S, Gröhn O., Event-recurring multiband SWIFT functional MRI with 200-ms temporal resolution during deep brain stimulation and isoflurane-induced burst suppression in rat, Magn Reson Med. 2022 Jun;87(6):2872-2884. doi: 10.1002/mrm.29154. Epub 2022 Jan 5.
Liu H, Cao J, Balluff B, Jongen ACHM, Gijbels MJ, Melenhorst J, Heeren RMA, Bouvy ND., Examination of lipid profiles in abdominal fascial healing using MALDI-TOF to identify potential therapeutic targets, J Mass Spectrom Adv Clin Lab. 2021 Jun 8;20:35-41. doi: 10.1016/j.jmsacl.2021.06.002. eCollection 2021 Apr.
Fritsch LJ, McCaulley SJ, Johnson CR, Lawson NJ, Gorres-Martens BK., Exercise prevents whole body type 2 diabetes risk factors better than estradiol replacement in rats., J Appl Physiol (1985). 2021 Nov 1;131(5):1520-1531. doi: 10.1152/japplphysiol.00098.2021. Epub 2021 Sep 30.
Wright, T. M., Fone, K. C., Langley-Evans, S. C., & Voigt, J. P. (2011), Exposure to maternal consumption of cafeteria diet during the lactation period programmes feeding behaviour in the rat, International Journal of Developmental Neuroscience : The Official Journal of the International Society for Developmental Neuroscience, 29(8), 785-793. doi:10.1016/j.ijdevneu.2011.09.007 [doi]
Schmitt MV, Reichel A, Liu X, Fricker G, Lienau P., Extension of the Mechanistic Tissue Distribution Model of Rodgers and Rowland by Systematic Incorporation of Lysosomal Trapping: Impact on Unbound Partition Coefficient and Volume of Distribution Predictions in the Rat, Drug Metab Dispos. 2021 Jan;49(1):53-61. doi: 10.1124/dmd.120.000161. Epub 2020 Nov 4.
De Cuyper A, Winkler D, TĂźtken T, Janssens GPJ, Clauss M., Fatty Acids of Microbial Origin in the Perirenal Fat of Rats (Rattus norvegicus domestica) and Guinea Pigs (Cavia porcellus) Fed Various Diets, Lipids. 2020 Jul;55(4):341-351. doi: 10.1002/lipd.12240. Epub 2020 Apr 28.
Willadsen M, Üngör M, Sługocka A, Schwarting RKW, Homberg JR, Wöhr M., Fear Extinction and Predictive Trait-Like Inter-Individual Differences in Rats Lacking the Serotonin Transporter, Int J Mol Sci. 2021 Jun 30;22(13):7088. doi: 10.3390/ijms22137088.
Blankenship, B., Eighmy, J. J., Hoffmann, G., Schroeder, M., Sharma, A. K., & Sorden, S. D. (2016)., Findings in historical control harlan RCCHan: WIST rats from 104-week oral gavage studies., Toxicologic Pathology, 44(7), 947-961. doi:10.1177/0192623316660768 [doi]
Blankenship, B., & Skaggs, H. (2013)., Findings in historical control harlan RCCHanTM: WIST rats from 4-, 13-, 26-week studies., Toxicologic Pathology, 41(3), 537-547. doi:10.1177/0192623312460925 [doi]
Gottschalk, M. G., Mortas, P., Haman, M., Ozcan, S., Biemans, B., & Bahn, S. (2018), Fluoxetine, not donepezil, reverses anhedonia, cognitive dysfunctions and hippocampal proteome changes during repeated social defeat exposure., European Neuropsychopharmacology : The Journal of the European College of Neuropsychopharmacology, 28(1), 195-210. doi:S0924-977X(17)31993-4 [pii]
Brown AJH, Bradley SJ, Marshall FH, Brown GA, Bennett KA, Brown J, Cansfield JE, Cross DM, de Graaf C, Hudson BD, Dwomoh L, Dias JM, Errey JC, Hurrell E, Liptrot J, Mattedi G, Molloy C, Nathan PJ, Okrasa K, Osborne G, Patel JC, Pickworth M, Robertson N, Shahabi S, Bundgaard C, Phillips K, Broad LM, Goonawardena AV, Morairty SR, Browning M, Perini F, Dawson GR, Deakin JFW, Smith RT, Sexton PM, Warneck J, Vinson M, Tasker T, Tehan BG, Teobald B, Christopoulos A, Langmead CJ, Jazayeri A, Cooke RM, Rucktooa P, Congreve MS, Weir M, Tobin AB., From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease, Cell. 2021 Nov 24;184(24):5886-5901.e22. doi: 10.1016/j.cell.2021.11.001.
Ferreira-Neto HC, Stern JE., Functional coupling between NMDA receptors and SK channels in rat hypothalamic magnocellular neurons: altered mechanisms during heart failure, J Physiol. 2021 Jan;599(2):507-520. doi: 10.1113/JP278910. Epub 2019 Dec 4.
Miguéns-Gómez A, Grau-Bové C, Sierra-Cruz M, Jorba-Martín R, Caro A, Rodríguez-Gallego E, Beltrán-Debón R, Blay MT, Terra X, Ardévol A, Pinent M., Gastrointestinally Digested Protein from the Insect Alphitobius diaperinus Stimulates a Different Intestinal Secretome than Beef or Almond, Producing a Differential Response in Food Intake in Rats, Nutrients. 2020 Aug 7;12(8):2366. doi: 10.3390/nu12082366.
Vavers E, Zvejniece B, Stelfa G, Svalbe B, Vilks K, Kupats E, Mezapuke R, Lauberte L, Dambrova M, Zvejniece L., Genetic inactivation of the sigma-1 chaperone protein results in decreased expression of the R2 subunit of the GABA-B receptor and increased susceptibility to seizures, Neurobiol Dis. 2021 Mar;150:105244. doi: 10.1016/j.nbd.2020.105244. Epub 2020 Dec 30.
Vestlund, Jesper; Bergquist, Filip; Eckernäs, Daniel; Licheri, Valentina; Adermark, Louise; Jerlhag, Elisabet;, Ghrelin signalling within the rat nucleus accumbens and skilled reach foraging., Psychoneuroendocrinology Vol.106, 2019
Vallöf, Daniel; Vestlund, Jesper; Jerlhag, Elisabet;, Glucagon-like peptide-1 receptors within the nucleus of the solitary tract regulate alcohol-mediated behaviors in rodents., Neuropharmacology Vol.149, 2019
Vozella V, Cruz B, Natividad LA, Benvenuti F, Cannella N, Edwards S, Zorrilla EP, Ciccocioppo R, Roberto M., Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats, Int J Mol Sci. 2021 Mar 18;22(6):3095. doi: 10.3390/ijms22063095.
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Bradley, A. E., & Keane, K. (2011)., Neurooncology, Toxicologic Pathology, 39(1), 124-128. doi:10.1177/0192623310389477 [doi]
Bolli, M. H., Abele, S., Birker, M., Bravo, R., Bur, D., de Kanter, R., . . . Weller, T. (2014)., Novel S1P(1) receptor agonists--part 3: From thiophenes to pyridines, Journal of Medicinal Chemistry, 57(1), 110-130. doi:10.1021/jm4014696 [doi]
Meregalli C, Maricich Y, Cavaletti G, Canta A, Carozzi VA, Chiorazzi A, Newbold E, Marmiroli P, Ceresa C, Diani A, Papapetropoulos S, Lee MS., Reversal of Bortezomib-Induced Neurotoxicity by Suvecaltamide, a Selective T-Type Ca-Channel Modulator, in Preclinical Models, Cancers (Basel). 2021 Oct 7;13(19):5013. doi: 10.3390/cancers13195013.
Empl, M. T., Kammeyer, P., Ulrich, R., Joseph, J. F., Parr, M. K., Willenberg, I., . . . Steinberg, P. (2014), The influence of chronic L-carnitine supplementation on the formation of preneoplastic and atherosclerotic lesions in the colon and aorta of male F344 rats., Archives of Toxicology, doi:10.1007/s00204-014-1341-4 [doi]
Colli-Dula, R. C., Friedman, M. A., Hansen, B., & Denslow, N. D. (2016), Transcriptomics analysis and hormonal changes of male and female neonatal rats treated chronically with a low dose of acrylamide in their drinking water., Toxicology Reports, 3, 414-426. doi:10.1016/j.toxrep.2016.03.009 [doi]
Maronpot, R. R., Thoolen, R. J., & Hansen, B. (2015), Two-year carcinogenicity study of acrylamide in wistar han rats with in utero exposure., Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie, 67(2), 189-195. doi:10.1016/j.etp.2014.11.009 [doi]
Voshart DC, Oshima T, Jiang Y, van der Linden GP, Ainslie AP, Reali Nazario L, van Buuren-Broek F, Scholma AC, van Weering HRJ, Brouwer N, Sewdihal J, Brouwer U, Coppes RP, Holtman IR, Eggen BJL, Kooistra SM, Barazzuol L., Radiotherapy induces persistent innate immune reprogramming of microglia into a primed state., Cell Rep. 2024 Feb 27;43(2):113764. doi: 10.1016/j.celrep.2024.113764. Epub 2024 Feb 14.
Other
Brinkman CL, Schmidt-Malan SM, Karau MJ, Patel R., A novel rat model of foreign body osteomyelitis for evaluation of antimicrobial efficacy, J Exp Appl Anim Sci. 2019;3(1):7-14. doi: 10.20454/jeaas.2019.1555.
Mota F, Pell VR, Singh N, Baark F, Waters E, Sadasivam P, Southworth R, Yan R., A Reactivity-Based (18)F-Labeled Probe for PET Imaging of Oxidative Stress in Chemotherapy-Induced Cardiotoxicity., Mol Pharm. 2021 Nov 30. doi: 10.1021/acs.molpharmaceut.1c00496. [Epub ahead of print]
Testai L, De Leo M, Flori L, Polini B, Braca A, Nieri P, Pistelli L, Calderone V., Contribution of irisin pathway in protective effects of mandarin juice (Citrus reticulata Blanco) on metabolic syndrome in rats fed with high fat diet., Phytother Res. 2021 Aug;35(8):4324-4333. doi: 10.1002/ptr.7128. Epub 2021 May 4.
Kalafateli AL, Vestlund J, Raun K, Egecioglu E, Jerlhag E., Effects of a selective long-acting amylin receptor agonist on alcohol consumption, food intake and body weight in male and female rats., Addict Biol. 2021 Mar;26(2):e12910. doi: 10.1111/adb.12910. Epub 2020 May 8.
Cordaro M, Salinaro AT, Siracusa R, D'Amico R, Impellizzeri D, Scuto M, Ontario ML, Cuzzocrea S, Di Paola R, Fusco R, Calabrese V., Key Mechanisms and Potential Implications of Hericium erinaceus in NLRP3 Inflammasome Activation by Reactive Oxygen Species during Alzheimer's Disease., Antioxidants (Basel). 2021 Oct 22;10(11). pii: 1664. doi: 10.3390/antiox10111664.
Carling CJ, Brülls M., Milling of poorly soluble crystalline drug compounds to generate appropriate particle sizes for inhaled sustained drug delivery, Int J Pharm. 2021 Jan 25;593:120116. doi: 10.1016/j.ijpharm.2020.120116. Epub 2020 Nov 25.
Huarte J, Espuelas S, Martínez-Oharriz C, Irache JM., Nanoparticles from Gantrez-based conjugates for the oral delivery of camptothecin, Int J Pharm X. 2021 Nov 9;3:100104. doi: 10.1016/j.ijpx.2021.100104. eCollection 2021 Dec.
Renko JM, Mahato AK, Visnapuu T, Valkonen K, Karelson M, Voutilainen MH, Saarma M, Tuominen RK, Sidorova YA., Neuroprotective Potential of a Small Molecule RET Agonist in Cultured Dopamine Neurons and Hemiparkinsonian Rats., J Parkinsons Dis. 2021;11(3):1023-1046. doi: 10.3233/JPD-202400.
Zhao X, Kruzel M, Ting SM, Sun G, Savitz SI, Aronowski J., Optimized lactoferrin as a highly promising treatment for intracerebral hemorrhage: Pre-clinical experience, J Cereb Blood Flow Metab. 2021 Jan;41(1):53-66. doi: 10.1177/0271678X20925667. Epub 2020 May 21.
Dettori I, Gaviano L, Ugolini F, Lana D, Bulli I, Magni G, Rossi F, Giovannini MG, Pedata F., Protective Effect of Adenosine A(2B) Receptor Agonist, BAY60-6583, Against Transient Focal Brain Ischemia in Rat., Front Pharmacol. 2021 Feb 11;11:588757. doi: 10.3389/fphar.2020.588757. eCollection 2020.
Bigaud M, Rudolph B, Briard E, Beerli C, Hofmann A, Hermes E, Muellershausen F, Schubart A, Gardin A., Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights, Mult Scler J Exp Transl Clin. 2021 Nov 3;7(4):20552173211049168. doi: 10.1177/20552173211049168. eCollection 2021 Oct.
Swetledge S, Carter R, Stout R, Astete CE, Jung JP, Sabliov CM., Stability and ocular biodistribution of topically administered PLGA nanoparticles., Sci Rep. 2021 Jun 10;11(1):12270. doi: 10.1038/s41598-021-90792-5.
Danielsson K, et al., Subregion-specific effects on striatal neurotransmission and dopamine-signaling by acute and repeated amphetamine exposure., Neuropharmacology. 2021 Aug 15;194:108638. doi: 10.1016/j.neuropharm.2021.108638. Epub 2021 Jun 8.
Natsheh JY, Espinoza D, Bhimani S, Shiflett MW., The effects of the dopamine D2/3 agonist quinpirole on incentive value and palatability-based choice in a rodent model of attention-deficit/hyperactivity disorder., Psychopharmacology (Berl). 2021 Nov;238(11):3143-3153. doi: 10.1007/s00213-021-05931-7. Epub 2021 Jul 27.
Beatty R, Lu CE, Marzi J, Levey RE, Carvajal Berrio D, Lattanzi G, Wylie R, O'Connor R, Wallace E, Ghersi G, Salamone M, Dolan EB, Layland SL, Schenke-Layland K, Duffy GP., The Foreign Body Response to an Implantable Therapeutic Reservoir in a Diabetic Rodent Model., Tissue Eng Part C Methods. 2021 Oct;27(10):515-528. doi: 10.1089/ten.TEC.2021.0163.
Ursic, M, Babic, A, et al., The Impact of Cannabidiol on the Induction of Isoflurane Anesthesia and Recovery in Wistar Rats., Cannabis Cannabinoid Res. 2021 May 11. doi: 10.1089/can.2021.0014. [Epub ahead of print]
Brotons-Canto A, González-Navarro CJ, Gil AG, Asin-Prieto E, Saiz MJ, Llabrés JM., Zein Nanoparticles Improve the Oral Bioavailability of Curcumin in Wistar Rats., Pharmaceutics. 2021 Mar 9;13(3). pii: 361. doi: 10.3390/pharmaceutics13030361.
Preclinical (PK/PD)
Gustafsson Å, Wang B, Gerde P, Bergman Å, Yeung LWY., Bioavailability of inhaled or ingested PFOA adsorbed to house dust, Environ Sci Pollut Res Int. 2022 Nov;29(52):78698-78710. doi: 10.1007/s11356-022-20829-3. Epub 2022 Jun 14.
Somvanshi RK, Zou S, Kadhim S, Padania S, Hsu E, Kumar U., Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma, Biochim Biophys Acta Mol Basis Dis. 2022 Mar 1;1868(3):166325. doi: 10.1016/j.bbadis.2021.166325. Epub 2021 Dec 16.
Sydney-Smith JD, Koltchev AM, Moon LDF, Warren PM., Delayed viral vector mediated delivery of neurotrophin-3 improves skilled hindlimb function and stability after thoracic contusion., Exp Neurol. 2023 Feb;360:114278. doi: 10.1016/j.expneurol.2022.114278. Epub 2022 Nov 28.
Pacławski A, Politis S, Balafas E, Mina E, Papakyriakopoulou P, Christodoulou E, Kostomitsopoulos N, Rekkas DM, Valsami G, Giovagnoli S., Development and Pharmacokinetics of a Novel Acetylsalicylic Acid Dry Powder for Pulmonary Administration, Pharmaceutics. 2022 Dec 15;14(12):2819. doi: 10.3390/pharmaceutics14122819.
Milton-Laskibar I, Cuevas-Sierra A, Portillo MP, Martínez JA., Effects of Resveratrol Administration in Liver Injury Prevention as Induced by an Obesogenic Diet: Role of Ruminococcaceae, Biomedicines. 2022 Jul 26;10(8):1797. doi: 10.3390/biomedicines10081797.
Konijnenberg LSF, Luiken TTJ, Veltien A, Uthman L, Kuster CTA, Rodwell L, de Waard GA, Kea-Te Lindert M, Akiva A, Thijssen DHJ, Nijveldt R, van Royen N., Imatinib attenuates reperfusion injury in a rat model of acute myocardial infarction, Basic Res Cardiol. 2023 Jan 13;118(1):2. doi: 10.1007/s00395-022-00974-z.
Hyppönen V, Stenroos P, Nivajärvi R, Ardenkjaer-Larsen JH, Gröhn O, Paasonen J, Kettunen MI., Metabolism of hyperpolarised [1-(13) C]pyruvate in awake and anaesthetised rat brains, NMR Biomed. 2022 Feb;35(2):e4635. doi: 10.1002/nbm.4635. Epub 2021 Oct 21.
Karsten S, Fiskesund R, Zhang XM, Marttila P, Sanjiv K, Pham T, Rasti A, Bräutigam L, Almlöf I, Marcusson-Ståhl M, Sandman C, Platzack B, Harris RA, Kalderén C, Cederbrant K, Helleday T, Warpman Berglund U., MTH1 as a target to alleviate T cell driven diseases by selective suppression of activated T cells, Cell Death Differ. 2022 Jan;29(1):246-261. doi: 10.1038/s41418-021-00854-4.
Ravula A, Chandasana H, Jagnarine D, Wall SC, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats, Cannabis Cannabinoid Res. 2019 Dec 6;4(4):240-254. doi: 10.1089/can.2019.0049. eCollection 2019.
Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant, J Pharm Biomed Anal. 2018 Oct 25;160:119-125. doi: 10.1016/j.jpba.2018.07.004. Epub 2018 Jul 19.
Campión R, Gonzalez-Navarro CJ, Luisa Martínez López A, Cristina Martínez-Oharriz M, Matías C, Sáiz-Abajo MJ, Collantes M, Peñuelas I, Irache JM., Zein-based nanospheres and nanocapsules for the encapsulation and oral delivery of quercetin, Int J Pharm. 2023 Aug 25;643:123216. doi: 10.1016/j.ijpharm.2023.123216. Epub 2023 Jul 8.
Zheng J, Lu B, Carr G, Mwangi J, Wang K, Hao J, Staiger KM, Kozon N, Murray BP, Bashir M, Gohdes MA, Tse WC, Schroeder S, Graupe M, Link JO, Yoon J, Chiu A, Rowe W, Smith BJ, Subramanian R., Lenacapavir Exhibits Atropisomerism-Mechanistic Pharmacokinetics and Disposition Studies of Lenacapavir Reveal Intestinal Excretion as a Major Clearance Pathway, J Pharmacol Exp Ther. 2024 Sep 18;391(1):91-103. doi: 10.1124/jpet.124.002302.
Surgical
Mazzini GS, Khoraki J, Browning MG, Wu J, Zhou H, Price ET, Wolfe LG, Mangino MJ, Campos GM., Gastric Bypass Increases Circulating Bile Acids and Activates Hepatic Farnesoid X Receptor (FXR) but Requires Intact Peroxisome Proliferator Activator Receptor Alpha (PPARÎą) Signaling to Significantly Reduce Liver Fat Content., J Gastrointest Surg. 2021 Apr;25(4):871-879. doi: 10.1007/s11605-021-04908-3. Epub 2021 Feb 8.
Hyppönen V, Stenroos P, Nivajärvi R, Ardenkjaer-Larsen JH, Gröhn O, Paasonen J, Kettunen MI., Metabolism of hyperpolarised [1-(13) C]pyruvate in awake and anaesthetised rat brains, NMR Biomed. 2021 Oct 21:e4635. doi: 10.1002/nbm.4635. Online ahead of print.
Ravula A, Chandasana H, Jagnarine D, Wall SC, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Pharmacokinetic and Pharmacodynamic Characterization of Tetrahydrocannabinol-Induced Cannabinoid Dependence After Chronic Passive Cannabis Smoke Exposure in Rats, Cannabis Cannabinoid Res. 2019 Dec 6;4(4):240-254. doi: 10.1089/can.2019.0049. eCollection 2019.
Ravula A, Chandasana H, Setlow B, Febo M, Bruijnzeel AW, Derendorf H., Simultaneous quantification of cannabinoids tetrahydrocannabinol, cannabidiol and CB1 receptor antagonist in rat plasma: An application to characterize pharmacokinetics after passive cannabis smoke inhalation and co-administration of rimonabant, J Pharm Biomed Anal. 2018 Oct 25;160:119-125. doi: 10.1016/j.jpba.2018.07.004. Epub 2018 Jul 19.
Brandt MJV, Kosmeijer CM, Achterberg EJM, de Theije CGM, Nijboer CH., Timed fetal inflammation and postnatal hypoxia cause cortical white matter injury, interneuron imbalances, and behavioral deficits in a double-hit rat model of encephalopathy of prematurity, Brain Behav Immun Health. 2024 Jul 5;40:100817. doi: 10.1016/j.bbih.2024.100817. eCollection 2024 Oct.
Ourednik J, Ourednik V, Ghosh N, Snyder EY., Protocol to optimize the Rice-Vannucci rat pup model of perinatal asphyxia to ensure predictable hypoxic-ischemic cerebral lesions, STAR Protoc. 2024 Jun 21;5(2):103025. doi: 10.1016/j.xpro.2024.103025. Epub 2024 Jun 8.
van den Brom CE, Bozic C, Polet CA, Bongers A, Tuip-de Boer AM, Ibelings R, Roelofs JJTH, Juffermans NP., Effect of antibody-mediated connective tissue growth factor neutralization on lung edema in ventilator-induced lung injury in rats, Mol Med. 2024 May 22;30(1):68. doi: 10.1186/s10020-024-00829-4.
Teratology
Pospelov AS, Ala-Kurikka T, Kurki S, Voipio J, Kaila K., Carbonic anhydrase inhibitors suppress seizures in a rat model of birth asphyxia, Epilepsia. 2021 Aug;62(8):1971-1984. doi: 10.1111/epi.16963. Epub 2021 Jun 27.
Devonshire, I. M., Preston, M. J., Dommett, E. J., Murphy, K. L., & Greenfield, S. A. (2009), Design and evaluation of a low-cost respiratory monitoring device for use with anaesthetized animals, Laboratory Animals, 43(4), 382-389. doi:10.1258/la.2009.0080124 [doi]
Agterberg, M. J., Spoelstra, E. N., van der Wijst, S., Brakkee, J. H., Wiegant, V. M., Hamelink, R., . . . Remie, R. (2010), Evaluation of temperature rise and bonding strength in cements used for permanent head attachments in rats and mice, Laboratory Animals, 44(3), 264-270. doi:10.1258/la.2010.009083 [doi]
Nato G, Corti A, Parmigiani E, Jachetti E, Lecis D, Colombo MP, Delia D, Buffo A, Magrassi L., Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing, Sci Rep. 2021 Jan 12;11(1):651. doi: 10.1038/s41598-020-79502-9.
Clark, R. L., Edwards, T. L., Longo, M., Kinney, J., Walker, D. K., Rhodes, J., . . . Huber, A. C. (2018)., Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate, Birth Defects Research, 110(7), 553-578. doi:10.1002/bdr2.1170 [doi]
Santoro A, Scafuro M, Troisi J, Piegari G, Di Pietro P, Mele E, Cappetta D, Marino M, De Angelis A, Vecchione C, Paciello O, Fasano S, Pierantoni R, Viggiano A, Meccariello R., Multi-Systemic Alterations by Chronic Exposure to a Low Dose of Bisphenol A in Drinking Water: Effects on Inflammation and NAD(+)-Dependent Deacetylase Sirtuin1 in Lactating and Weaned Rats, Int J Mol Sci. 2021 Sep 7;22(18):9666. doi: 10.3390/ijms22189666.
Raez-Villanueva S, Debnath A, Hardy DB, Holloway AC., Prenatal nicotine exposure leads to decreased histone H3 lysine 9 (H3K9) methylation and increased p66shc expression in the neonatal pancreas., J Dev Orig Health Dis. 2021 May 28:1-5. doi: 10.1017/S2040174421000283. [Epub ahead of print]
Blesson CS, Schutt A, Chacko S, Marini JC, Mathew PR, Tanchico D, Balakrishnan M, Yallampalli C., Sex Dependent Dysregulation of Hepatic Glucose Production in Lean Type 2 Diabetic Rats, Front Endocrinol (Lausanne). 2019 Aug 6;10:538. doi: 10.3389/fendo.2019.00538. eCollection 2019.
Toxicology
Lina, B. A., Messinger, H., & Bar, A. (2015)., 13-week oral toxicity study of vinyl laurate in rats., Regulatory Toxicology and Pharmacology : RTP, 71(1), 101-107. doi:10.1016/j.yrtph.2014.10.015 [doi]
Morris PJ, Burke RD, Sharma AK, Lynch DC, Lemke-Boutcher LE, Mathew S, Elayan I, Rao DB, Gould TD, Zarate CA Jr, Zanos P, Moaddel R, Thomas CJ., A comparison of the pharmacokinetics and NMDAR antagonism-associated neurotoxicity of ketamine, (2R,6R)-hydroxynorketamine and MK-801, Neurotoxicol Teratol. 2021 Sep-Oct;87:106993. doi: 10.1016/j.ntt.2021.106993. Epub 2021 May 1.
Bartnikas, T. B., Wildt, S. J., Wineinger, A. E., Schmitz-Abe, K., Markianos, K., Cooper, D. M., & Fleming, M. D. (2013)., A novel rat model of hereditary hemochromatosis due to a mutation in transferrin receptor 2., Comparative Medicine, 63(2), 143-155.
Grandy, T. H., Greenfield, S. A., & Devonshire, I. M. (2012)., An evaluation of in vivo voltage-sensitive dyes: Pharmacological side effects and signal-to-noise ratios after effective removal of brain-pulsation artifacts., Journal of Neurophysiology, 108(11), 2931-2945. doi:10.1152/jn.00512.2011 [doi]
Salum, E., Butlin, M., Kals, J., Zilmer, M., Eha, J., Avolio, A. P., . . . Kampus, P. (2014), Angiotensin II receptor blocker telmisartan attenuates aortic stiffening and remodelling in STZ-diabetic rats, Diabetology & Metabolic Syndrome, 6, 57-5996-6-57. eCollection 2014. doi:10.1186/1758-5996-6-57 [doi]
Turpin, P. E., Burnett, J. E., Goodwin, L., Foster, A., & Barfield, M. (2010)., Application of the DBS methodology to a toxicokinetic study in rats and transferability of analysis between bioanalytical laboratories., Bioanalysis, 2(8), 1489-1499. doi:10.4155/bio.10.88 [doi]
Thompson CM, Brorby G, Keig-Shevlin Z, Smith R, Franzen A, Ulrich K, Blanchette AD, Doepker C., Assessment of the in vivo genotoxic potential of three smoke flavoring primary product mixtures., Environ Mol Mutagen. 2023 Oct-Nov;64(8-9):420-431. doi: 10.1002/em.22576. Epub 2023 Nov 30.
Silva AV, Norinder U, Liiv E, Platzack B, Öberg M, Törnqvist E., Associations between clinical signs and pathological findings in toxicity testing, ALTEX. 2020 Oct 26. doi: 10.14573/altex.2003311. Online ahead of print.
Barragin-Zarate GS, Alexander-Aguilera A, et al., Bioactive compounds from Prosthechea karwinskii decrease obesity, insulin resistance, pro-inflammatory status, and cardiovascular risk in Wistar rats with metabolic syndrome., J Ethnopharmacol. 2021 Oct 28;279:114376. doi: 10.1016/j.jep.2021.114376. Epub 2021 Jun 25.
Zuurbier, C. J., Heinen, A., Koeman, A., Stuifbergen, R., Hakvoort, T. B., Weber, N. C., & Hollmann, M. W. (2014)., Cardioprotective efficacy depends critically on pharmacological dose, duration of ischaemia, health status of animals and choice of anaesthetic regimen: A case study with folic acid., Journal of Translational Medicine, 12, 325-014-0325-8. doi:10.1186/s12967-014-0325-8 [doi]
Rodd ZA, Engleman EA, Truitt WA, Burke AR, Molosh AI, Bell RL, Hauser SR., CNO Administration Increases Dopamine and Glutamate in the Medial Prefrontal Cortex of Wistar Rats: Further Concerns for the Validity of the CNO-activated DREADD Procedure, Neuroscience. 2022 May 21;491:176-184. doi: 10.1016/j.neuroscience.2022.03.028. Epub 2022 Mar 26.
Hall, A. P., Davies, W., Stamp, K., Clamp, I., & Bigley, A. (2013), Comparison of computerized image analysis with traditional semiquantitative scoring of perls' prussian blue stained hepatic iron deposition., Toxicologic Pathology, 41(7), 992-1000. doi:10.1177/0192623313476576 [doi]
Roques, B. B., Lacroix, M. Z., Puel, S., Gayrard, V., Picard-Hagen, N., Jouanin, I., . . . Viguie, C. (2012)., CYP450-dependent biotransformation of the insecticide fipronil into fipronil sulfone can mediate fipronil-induced thyroid disruption in rats., Toxicological Sciences : An Official Journal of the Society of Toxicology, 127(1), 29-41. doi:10.1093/toxsci/kfs094 [doi]
Harris SB, Hardisty JF, Hayes AW, Weber K., Developmental and reproductive toxicity studies of BIA 10-2474, Regul Toxicol Pharmacol. 2020 Mar;111:104543. doi: 10.1016/j.yrtph.2019.104543. Epub 2019 Nov 20.
Jamison CN, Dayton RD, Latimer B, McKinney MP, Mitchell HG, McMartin KE., Diethylene glycol produces nephrotoxic and neurotoxic effects in female rats, Clin Toxicol (Phila). 2021 Jul 19:1-8. doi: 10.1080/15563650.2021.1953049. Online ahead of print.
Panknin O, Wagenfeld A, Bone W, Bender E, Nowak-Reppel K, Fernández-Montalván AE, Nubbemeyer R, Bäurle S, Ring S, Schmees N, Prien O, Schäfer M, Friedrich C, Zollner TM, Steinmeyer A, Mueller T, Langer G., Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women, J Med Chem. 2020 Oct 22;63(20):11854-11881. doi: 10.1021/acs.jmedchem.0c01076. Epub 2020 Oct 6.
Finlay, M. R., Anderton, M., Ashton, S., Ballard, P., Bethel, P. A., Box, M. R., . . . Wrigley, G. L. (2014)., Discovery of a potent and selective EGFR inhibitor (AZD9291) of both sensitizing and T790M resistance mutations that spares the wild type form of the receptor., Journal of Medicinal Chemistry, 57(20), 8249-8267. doi:10.1021/jm500973a [doi]
Bisson, J. F., Daubie, S., Hidalgo, S., Guillemet, D., & Linares, E. (2010)., Diuretic and antioxidant effects of cacti-nea, a dehydrated water extract from prickly pear fruit, in rats, Phytotherapy Research : PTR, 24(4), 587-594. doi:10.1002/ptr.2996 [doi]
Fennell, T. R., Snyder, R., Hansen, B., & Friedman, M. (2015)., Dosimetry of acrylamide and glycidamide over the lifespan in a 2-year bioassay of acrylamide in wistar han rats, Toxicological Sciences : An Official Journal of the Society of Toxicology, 146(2), 386-394. doi:10.1093/toxsci/kfv104 [doi]
Fennell, T. R., Snyder, R., Hansen, B., & Friedman, M. (2015)., Dosimetry of acrylamide and glycidamide over the lifespan in a 2-year bioassay of acrylamide in wistar han rats., Toxicological Sciences : An Official Journal of the Society of Toxicology, 146(2), 386-394. doi:10.1093/toxsci/kfv104 [doi]
Klose, M., Grote, K., Spathmann, O., Streckert, J., Clemens, M., Hansen, V. W., & Lerchl, A. (2014)., Effects of early-onset radiofrequency electromagnetic field exposure (GSM 900 MHz) on behavior and memory in rats., Radiation Research, 182(4), 435-447. doi:10.1667/RR13695.1 [doi]
Scott H, Tjernström N, Roman E., Effects of pair housing on voluntary alcohol intake in male and female Wistar rats, Alcohol. 2020 Aug;86:121-128. doi: 10.1016/j.alcohol.2019.12.005. Epub 2020 Jan 21.
Devonshire, I. M., Grandy, T. H., Dommett, E. J., & Greenfield, S. A. (2010), Effects of urethane anaesthesia on sensory processing in the rat barrel cortex revealed by combined optical imaging and electrophysiology., The European Journal of Neuroscience, 32(5), 786-797. doi:10.1111/j.1460-9568.2010.07322.x [doi]
Cupi D, Thorsen M, Elvig-Jørgensen SG, Wulf-Andersen L, Berti-Sorbara JO, J Cowieson A, Faruk MU., Efficacy and safety profile of a subtilisin protease produced by fermentation in Bacillus licheniformis to be used as a feed additive, Heliyon. 2022 Aug 2;8(8):e10030. doi: 10.1016/j.heliyon.2022.e10030. eCollection 2022 Aug.
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