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General studies

Chiu JE, Renard I, Pal AC, Singh P, Vydyam P, Thekkiniath J, Kumar M, Gihaz S, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Mamoun CB., Effective Therapy Targeting Cytochrome bc(1) Prevents Babesia Erythrocytic Development and Protects from Lethal Infection, Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0066221. doi: 10.1128/AAC.00662-21. Epub 2021 Aug 17.
Li, Fu; Ulrich, Michelle L; Shih, Vincent Feng-Sheng; Cochran, Julia H; Hunter, Joshua H; Westendorf, Lori; Neale, Jason; Benjamin, Dennis R;, Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-Fc?R Interaction, Molecular cancer therapeutics Vol.18, 2019

Imaging

Gill H, Seipert R, Carroll VM, Gouasmat A, Yin J, Ogasawara A, de Jong I, Phan MM, Wang X, Yang J, Ilovich O, Marik J, Williams SP, The Production, Quality Control, and Characterization of ZED8, a CD8-Specific, AAPS J. 2020 Jan 3;22(2):22.

Immunology

Liu, Z., Gunasekaran, K., Wang, W., Razinkov, V., Sekirov, L., Leng, E., . . . Yan, W. (2014)., Asymmetrical fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies., The Journal of Biological Chemistry, 289(6), 3571-3590. doi:10.1074/jbc.M113.513366 [doi]
Fang, R., Ismail, N., & Walker, D. H. (2012)., Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium., The American Journal of Pathology, 181(1), 185-195. doi:10.1016/j.ajpath.2012.03.020 [doi]
Wallach-Dayan, S. B., Elkayam, L., Golan-Gerstl, R., Konikov, J., Zisman, P., Dayan, M. R., . . . Breuer, R. (2015), Cutting edge: FasL(+) immune cells promote resolution of fibrosis., Journal of Autoimmunity, 59, 67-76. doi:10.1016/j.jaut.2015.02.006 [doi]
Chand M, Choi JY, Pal AC, Singh P, Kumari V, Thekkiniath J, Gagnon J, Timalsina S, Gaur G, Williams S, Ledizet M, Mamoun CB., Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti, Front Cell Infect Microbiol. 2022 Nov 25;12:1039197. doi: 10.3389/fcimb.2022.1039197. eCollection 2022.
Rogovskyy, A. S., Casselli, T., Tourand, Y., Jones, C. R., Owen, J. P., Mason, K. L., . . . Bankhead, T. (2015)., Evaluation of the importance of VlsE antigenic variation for the enzootic cycle of borrelia burgdorferi., PloS One, 10(4), e0124268. doi:10.1371/journal.pone.0124268 [doi]
Hossain, M., Qadri, S. M., & Liu, L. (2012)., Inhibition of nitric oxide synthesis enhances leukocyte rolling and adhesion in human microvasculature, Journal of Inflammation (London, England), 9(1), 28-9255-9-28. doi:10.1186/1476-9255-9-28 [doi]
Jones, R. J., Iempridee, T., Wang, X., Lee, H. C., Mertz, J. E., Kenney, S. C., . . . Orlowski, R. Z. (2016)., Lenalidomide, thalidomide, and pomalidomide reactivate the epstein-barr virus lytic cycle through phosphoinositide 3-kinase signaling and ikaros expression., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(19), 4901-4912. doi:1078-0432.CCR-15-2242 [pii]
Burette M, Allombert J, Lambou K, Maarifi G, Nisole S, Di Russo Case E, Blanchet FP, Hassen-Khodja C, Cabantous S, Samuel J, Martinez E, Bonazzi M., Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein, Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13708-13718. doi: 10.1073/pnas.1914892117. Epub 2020 Jun 1.
Case EDR, Mahapatra S, Hoffpauir CT, Konganti K, Hillhouse AE, Samuel JE, Van Schaik EJ., Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii, Microbiol Spectr. 2022 Aug 31;10(4):e0248421. doi: 10.1128/spectrum.02484-21. Epub 2022 Aug 1.
Gill, S., Vasey, A. E., De Souza, A., Baker, J., Smith, A. T., Kohrt, H. E., . . . Negrin, R. S. (2012)., Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells, Blood, 119(24), 5758-5768. doi:10.1182/blood-2012-03-415364 [doi]
Wintrob, Z. A., Oppong, E. K., Foster, M., Martorana, M., Tse, Y. C., Zhong, L., . . . Ceacareanu, A. C. (2014), Sexual dimorphism, weight gain and glucose intolerance in a B- and T-cell deficient mouse model., Cytokine, 67(2), 102-106. doi:10.1016/j.cyto.2014.02.011 [doi]
Manthey, Carl L; Moore, Beverley A; Chen, Yanqing; Loza, Matthew J; Yao, Xiang; Liu, Hao; Belkowski, Stanley M; Raymond-Parks, Holly; Dunford, Paul J; Leon, Francisco; Towne, Jennifer E; Plevy, Scott E;, The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis., PloS one Vol.14, 2019
Rosario, M., Liu, B., Kong, L., Collins, L. I., Schneider, S. E., Chen, X., . . . Fehniger, T. A. (2016)., The IL-15-based ALT-803 complex enhances FcgammaRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(3), 596-608. doi:10.1158/1078-0432.CCR-15-1419 [doi]
Felder, Mildred; Kapur, Arvinder; Rakhmilevich, Alexander L; Qu, Xiaoyi; Sondel, Paul M; Gillies, Stephen D; Connor, Joseph; Patankar, Manish S, UC16 suppresses human and murine innate immune responses., Gynecologic oncology Vol.152, 2019

Infectious disease

Pal AC, Renard I, Singh P, Vydyam P, Chiu JE, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Ben Mamoun C., Babesia duncani as a Model Organism to Study the Development, Virulence, and Drug Susceptibility of Intraerythrocytic Parasites In Vitro and In Vivo, J Infect Dis. 2022 Sep 28;226(7):1267-1275. doi: 10.1093/infdis/jiac181.
Chiu JE, Renard I, George S, Pal AC, Alday PH, Narasimhan S, Riscoe MK, Doggett JS, Ben Mamoun C., Cytochrome b Drug Resistance Mutation Decreases Babesia Fitness in the Tick Stages But Not the Mammalian Erythrocytic Cycle, J Infect Dis. 2022 Jan 5;225(1):135-145. doi: 10.1093/infdis/jiab321.
Chand M, Choi JY, Pal AC, Singh P, Kumari V, Thekkiniath J, Gagnon J, Timalsina S, Gaur G, Williams S, Ledizet M, Mamoun CB., Epitope profiling of monoclonal antibodies to the immunodominant antigen BmGPI12 of the human pathogen Babesia microti, Front Cell Infect Microbiol. 2022 Nov 25;12:1039197. doi: 10.3389/fcimb.2022.1039197. eCollection 2022.
Case EDR, Mahapatra S, Hoffpauir CT, Konganti K, Hillhouse AE, Samuel JE, Van Schaik EJ., Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii, Microbiol Spectr. 2022 Aug 31;10(4):e0248421. doi: 10.1128/spectrum.02484-21. Epub 2022 Aug 1.

Oncology

Avena P, Casaburi I, Zavaglia L, Nocito MC, La Padula D, Rago V, Dong J, Thomas P, Mineo C, Sirianni R, Shaul PW., 27-Hydroxycholesterol Binds GPER and Induces Progression of Estrogen Receptor-Negative Breast Cancer, Cancers (Basel). 2022 Mar 16;14(6):1521. doi: 10.3390/cancers14061521.
Singh D, Deosarkar SP, Cadogan E, Flemington V, Bray A, Zhang J, Reiserer RS, Schaffer DK, Gerken GB, Britt CM, Werner EM, Gibbons FD, Kostrzewski T, Chambers CE, Davies EJ, Montoya AR, Fok JHL, Hughes D, Fabre K, Wagoner MP, Wikswo JP, Scott CW., A microfluidic system that replicates pharmacokinetic (PK) profiles in vitro improves prediction of in vivo efficacy in preclinical models, PLoS Biol. 2022 May 26;20(5):e3001624. doi: 10.1371/journal.pbio.3001624. eCollection 2022 May.
Caban, M., Koblmueller, B., Groza, D., Schueffl, H. H., Terenzi, A., Tolios, A., Mohr, T., Mathuber, M., Kryeziu, K., Jaunecker, C., Pirker, C., Keppler, B. K., Berger, W., Kowol, C. R., & Heffeter, P., A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo, Cancer letters, 565, 216237. https://doi.org/10.1016/j.canlet.2023.216237
Jeffrey, S. C., Burke, P. J., Lyon, R. P., Meyer, D. W., Sussman, D., Anderson, M., . . . Senter, P. D. (2013)., A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology., Bioconjugate Chemistry, 24(7), 1256-1263. doi:10.1021/bc400217g [doi]
Yeom DH, Lee YS, Ryu I, Lee S, Sung B, Lee HB, Kim D, Ahn JH, Ha E, Choi YS, Lee SH, You WK., ABL001, a Bispecific Antibody Targeting VEGF and DLL4, with Chemotherapy, Synergistically Inhibits Tumor Progression in Xenograft Models, Int J Mol Sci. 2020 Dec 29;22(1):241. doi: 10.3390/ijms22010241.
Unno K, Chalmers ZR, Pamarthy S, Vatapalli R, Rodriguez Y, Lysy B, Mok H, Sagar V, Han H, Yoo YA, Ku SY, Beltran H, Zhao Y, Abdulkadir SA., Activated ALK Cooperates with N-Myc via Wnt/?-Catenin Signaling to Induce Neuroendocrine Prostate Cancer, Cancer Res. 2021 Apr 15;81(8):2157-2170. doi: 10.1158/0008-5472.CAN-20-3351. Epub 2021 Feb 26.
Thomas A, Samykutty A, Gomez-Gutierrez JG, Yin W, Egger ME, McNally M, Chuong P, MacCuaig WM, Albeituni S, Zeiderman M, Li M, Edil BH, Grizzle WE, McMasters KM, McNally LR., Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo, Cancers (Basel). 2020 Aug 14;12(8):2279. doi: 10.3390/cancers12082279.
Mahasreshti, P. J., Navarro, J. G., Kataram, M., Wang, M. H., Carey, D., Siegal, G. P., . . . Curiel, D. T. (2001), Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 7(7), 2057-2066.
Sutherland, M. K., Yu, C., Lewis, T. S., Miyamoto, J. B., Morris-Tilden, C. A., Jonas, M., . . . Law, C. L. (2009)., Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia., Mabs, 1(5), 481-490. doi:9288 [pii]
Abuqayyas, L., & Balthasar, J. P. (2012)., Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer., Journal of Pharmacokinetics and Pharmacodynamics, 39(6), 683-710. doi:10.1007/s10928-012-9279-8 [doi]
Ghilu S, Morton CL, Vaseva AV, Zheng S, Kurmasheva RT, Houghton PJ., Approaches to identifying drug resistance mechanisms to clinically relevant treatments in childhood rhabdomyosarcoma, Cancer Drug Resist. 2022;5(1):80-89. doi: 10.20517/cdr.2021.112. Epub 2022 Jan 4.
Liu C, Armstrong CM, Ning S, Yang JC, Lou W, Lombard AP, Zhao J, Wu CY, Yu A, Evans CP, Tepper CG, Li PK, Gao AC., ARVib suppresses growth of advanced prostate cancer via inhibition of androgen receptor signaling, Oncogene. 2021 Sep;40(35):5379-5392. doi: 10.1038/s41388-021-01914-2. Epub 2021 Jul 16.
Heyza JR, Ekinci E, Lindquist J, Lei W, Yunker C, Vinothkumar V, Rowbotham R, Polin L, Snider NG, Van Buren E, Watza D, Back JB, Chen W, Mamdani H, Schwartz AG, Turchi JJ, Bepler G, Patrick SM., ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe, NAR Cancer. 2023 Jan 11;5(1):zcac045. doi: 10.1093/narcan/zcac045. eCollection 2023 Mar.
Heyza JR, Ekinci E, Lindquist J, Lei W, Yunker C, Vinothkumar V, Rowbotham R, Polin L, Snider NG, Van Buren E, Watza D, Back JB, Chen W, Mamdani H, Schwartz AG, Turchi JJ, Bepler G, Patrick SM., ATR inhibition overcomes platinum tolerance associated with ERCC1- and p53-deficiency by inducing replication catastrophe., NAR Cancer. 2023 Jan 11;5(1):zcac045. doi: 10.1093/narcan/zcac045. eCollection 2023 Mar.
Do, T. V., Hirst, J., Hyter, S., Roby, K. F., & Godwin, A. K. (2017)., Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cells., Oncotarget, 8(31), 50376-50392. doi:10.18632/oncotarget.18970 [doi]
Zhang, L., Nomie, K., Zhang, H., Bell, T., Pham, L., Kadri, S., . . . Wang, M. (2017), B-cell lymphoma patient-derived xenograft models enable drug discovery and are a platform for personalized therapy., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(15), 4212-4223. doi:10.1158/1078-0432.CCR-16-2703 [doi]
Wei J, Yin L, Li J, Wang J, Pu T, Duan P, Lin TP, Gao AC, Wu BJ., Bidirectional Cross-talk between MAOA and AR Promotes Hormone-Dependent and Castration-Resistant Prostate Cancer, Cancer Res. 2021 Aug 15;81(16):4275-4289. doi: 10.1158/0008-5472.CAN-21-0198. Epub 2021 Jun 24.
Ning S, Liu C, Lou W, Yang JC, Lombard AP, D'Abronzo LS, Batra N, Yu AM, Leslie AR, Sharifi M, Evans CP, Gao AC., Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment, Mol Cancer Ther. 2022 Oct 7;21(10):1594-1607. doi: 10.1158/1535-7163.MCT-22-0216.
Zhang, C. C., Pavlicek, A., Zhang, Q., Lira, M. E., Painter, C. L., Yan, Z., . . . Christensen, J. G. (2012)., Biomarker and pharmacologic evaluation of the gamma-secretase inhibitor PF-03084014 in breast cancer models., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(18), 5008-5019. doi:10.1158/1078-0432.CCR-12-1379 [doi]
Francisco, J. A., Cerveny, C. G., Meyer, D. L., Mixan, B. J., Klussman, K., Chace, D. F., . . . Wahl, A. F. (2003)., cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity., Blood, 102(4), 1458-1465. doi:10.1182/blood-2003-01-0039 [doi]
Bhatta, Puspanjali; Dhukhwa, Asmita; Sheehan, Kelly; Al Aameri, Raheem F H; Borse, Vikrant; Ghosh, Sumana; Sheth, Sandeep; Mamillapalli, Chaitanya; Rybak, Leonard; Ramkumar, Vickram; Mukherjea, Debashree;, Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea., Scientific reports Vol.9, 2019
McKnight BN, Kim S, Boerner JL, Viola NT., Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer, Breast Cancer Res. 2020 Apr 15;22(1):37. doi: 10.1186/s13058-020-01270-1.
Kryeziu, K., Pirker, C., Englinger, B., van Schoonhoven, S., Spitzwieser, M., Mohr, T., . . . Heffeter, P. (2016), Chronic arsenic trioxide exposure leads to enhanced aggressiveness via met oncogene addiction in cancer cells, Oncotarget, 7(19), 27379-27393. doi:10.18632/oncotarget.8415 [doi]
Cocco, E., Shapiro, E. M., Gasparrini, S., Lopez, S., Schwab, C. L., Bellone, S., . . . Santin, A. D. (2015)., Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer, International Journal of Cancer, 137(11), 2618-2629. doi:10.1002/ijc.29632 [doi]
Balkin, E. R., Liu, D., Jia, F., Ruthengael, V. C., Shaffer, S. M., Miller, W. H., & Lewis, M. R. (2014)., Comparative biodistributions and dosimetry of [(1)(7)(7)lu]DOTA-anti-bcl-2-PNA-tyr(3)-octreotate and [(1)(7)(7)lu]DOTA-tyr(3)-octreotate in a mouse model of B-cell lymphoma/leukemia., Nuclear Medicine and Biology, 41(1), 36-42. doi:10.1016/j.nucmedbio.2013.10.006 [doi]
Glaser, G., Weroha, S. J., Becker, M. A., Hou, X., Enderica-Gonzalez, S., Harrington, S. C., & Haluska, P. (2015)., Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft, PloS One, 10(5), e0126867. doi:10.1371/journal.pone.0126867 [doi]
Jia, F., Balaji, B. S., Gallazzi, F., & Lewis, M. R. (2015)., Copper-64-labeled anti-bcl-2 PNA-peptide conjugates selectively localize to bcl-2-positive tumors in mouse models of B-cell lymphoma., Nuclear Medicine and Biology, doi:S0969-8051(15)00094-3 [pii]
Aregueta-Robles, U., Fajardo-Ramirez, O. R., Villela, L., Gutierrez-Uribe, J. A., Hernandez-Hernandez, J., Lopez-Sanchez, R. D. C., . . . Serna-Saldivar, S. (2018)., Cytotoxic activity of a black bean (phaseolus vulgaris L.) extract and its flavonoid fraction in both in vitro and in vivo models of lymphoma., Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, 70(1), 32-39. doi:10.24875/RIC.17002395 [doi]
Kinneer K, Wortmann P, Cooper ZA, Dickinson NJ, Masterson L, Cailleau T, Hutchinson I, Vijayakrishnan B, McFarlane M, Ball K, Davies M, Lewis A, Huang Y, Rosenbaum AI, Yuan J, Chesebrough J, Anderton J, Monks N, Novick S, Wang J, Dimasi N, Christie RJ, et al., Design and Preclinical Evaluation of a Novel B7-H4-Directed Antibody-Drug Conjugate, AZD8205, Alone and in Combination with the PARP1-Selective Inhibitor AZD5305., Clin Cancer Res. 2023 Mar 14;29(6):1086-1101. doi: 10.1158/1078-0432.CCR-22-2630.
Tymon-Rosario J, Bonazzoli E, Bellone S, Manzano A, Pelligra S, Guglielmi A, Gnutti B, Nagarkatti N, Zeybek B, Manara P, Zammataro L, Harold J, Mauricio D, Buza N, Hui P, Altwerger G, Menderes G, Ratner E, Clark M, Andikyan V, Huang GS, Silasi DA, Azodi M, Schwartz PE, Santin AD., DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo, Gynecol Oncol. 2021 Nov;163(2):334-341. doi: 10.1016/j.ygyno.2021.08.014. Epub 2021 Aug 25.
Hamblett, K. J., Senter, P. D., Chace, D. F., Sun, M. M., Lenox, J., Cerveny, C. G., . . . Francisco, J. A. (2004)., Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 10(20), 7063-7070. doi:10/20/7063 [pii]
Romani, C., Cocco, E., Bignotti, E., Moratto, D., Bugatti, A., Todeschini, P., . . . Mitola, S. (2015), Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery, Oncotarget, 6(33), 34617-34628. doi:10.18632/oncotarget.5315 [doi]
Harrison D, Gill J, Roth M, Hingorani P, Zhang W, Teicher B, Earley E, Erickson S, Gatto G, Kurmasheva R, Houghton P, Smith M, Anders Kolb E, Gorlick R., Evaluation of the pan-class I phosphoinositide 3-kinase (PI3K) inhibitor copanlisib in the Pediatric Preclinical Testing Consortium in vivo models of osteosarcoma, Pediatr Blood Cancer. 2023 Jan;70(1):e30017. doi: 10.1002/pbc.30017. Epub 2022 Oct 17.
Harrison D, Gill J, Roth M, Hingorani P, Zhang W, Teicher B, Earley E, Erickson S, Gatto G, Kurmasheva R, Houghton P, Smith M, Anders Kolb E, Gorlick R., Evaluation of the pan-class I phosphoinositide 3-kinase (PI3K) inhibitor copanlisib in the Pediatric Preclinical Testing Consortium in vivo models of osteosarcoma., Pediatr Blood Cancer. 2023 Jan;70(1):e30017. doi: 10.1002/pbc.30017. Epub 2022 Oct 17.
Budzik KM, Nace RA, Ikeda Y, Russell SJ., Evaluation of the stability and intratumoral delivery of foreign transgenes encoded by an oncolytic Foamy Virus vector, Cancer Gene Ther. 2022 Aug;29(8-9):1240-1251. doi: 10.1038/s41417-022-00431-y. Epub 2022 Feb 10.
Wang F, Liu Y, Qiu W, Shum E, Feng M, Zhao D, Zheng D, Borczuk A, Cheng H, Halmos B., Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination, Cancer Res. 2022 Apr 1;82(7):1365-1379. doi: 10.1158/0008-5472.CAN-21-1327.
Dingli, D., Diaz, R. M., Bergert, E. R., O'Connor, M. K., Morris, J. C., & Russell, S. J. (2003)., Genetically targeted radiotherapy for multiple myeloma, Blood, 102(2), 489-496. doi:10.1182/blood-2002-11-3390 [doi]
Gallo Cantafio ME, Torcasio R, Scionti F, Mesuraca M, Ronchetti D, Pistoni M, Bellizzi D, Passarino G, Morelli E, Neri A, Viglietto G, Amodio N., GPER1 Activation Exerts Anti-Tumor Activity in Multiple Myeloma., Cells. 2023 Sep 7;12(18). pii: 2226. doi: 10.3390/cells12182226.
Han, Chanhee; Perrone, Emanuele; Zeybek, Burak; Bellone, Stefania; Tymon-Rosario, Joan; Altwerger, Gary; Menderes, Gulden; Feinberg, Jacqueline; Haines, Kaitlin; Muller Karger, Mariana Espinal; Bianchi, Anna; Zammataro, Luca; Manzano, Aranzazu; Bonazzoli, Elena; Manara, Paola; Buza, Natalia; Hui, Pei; Ratner, Elena; Silasi, Dan-Arin; Huang, Gloria S; Azodi, Masoud; Schwartz, Peter E; Lopez, Salvatore; Santin, Alessandro D, In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma., Gynecologic oncology Vol.10, 2019
Zhang, L., Pham, L. V., Newberry, K. J., Ou, Z., Liang, R., Qian, J., . . . Wang, M. (2013)., In vitro and in vivo therapeutic efficacy of carfilzomib in mantle cell lymphoma: Targeting the immunoproteasome., Molecular Cancer Therapeutics, 12(11), 2494-2504. doi:10.1158/1535-7163.MCT-13-0156 [doi]
Mutlu L, Manavella DD, Bellone S, McNamara B, Harold JA, Mauricio D, Siegel ER, Buza N, Hui P, Hartwich TMP, Yang-Hartwich Y, Demirkiran C, Verzosa MSZ, Altwerger G, Ratner ES, Huang GS, Clark M, Andikyan V, Azodi M, Dottino PR, Schwartz PE, Santin AD., In Vivo and In Vitro Efficacy of Trastuzumab Deruxtecan in Uterine Serous Carcinoma., Mol Cancer Ther. 2023 Dec 1;22(12):1404-1412. doi: 10.1158/1535-7163.MCT-23-0126.
Han C, Perrone E, Zeybek B, Bellone S, Tymon-Rosario J, Altwerger G, Menderes G, Feinberg J, Haines K, Muller Karger ME, Bianchi A, Zammataro L, Manzano A, Bonazzoli E, Manara P, Buza N, Hui P, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Lopez S, Santin AD., In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma, Gynecol Oncol. 2020 Feb;156(2):430-438. doi: 10.1016/j.ygyno.2019.11.018. Epub 2019 Dec 12.
Lu, A., Pallero, M. A., Lei, W., Hong, H., Yang, Y., Suto, M. J., & Murphy-Ullrich, J. E. (2016), Inhibition of transforming growth factor-beta activation diminishes tumor progression and osteolytic bone disease in mouse models of multiple myeloma., The American Journal of Pathology, 186(3), 678-690. doi:10.1016/j.ajpath.2015.11.003 [doi]
Jones RJ, Singh RK, Shirazi F, Wan J, Wang H, Wang X, Ha MJ, Baljevic M, Kuiatse I, Davis RE, Orlowski RZ., Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors, Front Immunol. 2020 Aug 13;11:1816. doi: 10.3389/fimmu.2020.01816. eCollection 2020.
Gross, A. C., Cam, H., Phelps, D. A., Saraf, A. J., Bid, H. K., Cam, M., . . . Roberts, R. D. (2018), L-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis., JCI Insight, 3(16), 10.1172/jci.insight.99791. doi:10.1172/jci.insight.99791 [doi]
Junttila, T. T., Akita, R. W., Parsons, K., Fields, C., Lewis Phillips, G. D., Friedman, L. S., . . . Sliwkowski, M. X. (2009)., Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941., Cancer Cell, 15(5), 429-440. doi:10.1016/j.ccr.2009.03.020 [doi]
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Cai Q, Zhou W, Wang W, Dong B, Han D, Shen T, Creighton CJ, Moore DD, Yang F., MAPK6-AKT signaling promotes tumor growth and resistance to mTOR kinase blockade, Sci Adv. 2021 Nov 12;7(46):eabi6439. doi: 10.1126/sciadv.abi6439. Epub 2021 Nov 12.
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Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, MĂźller R, Wagner E, Vollmar AM, Zahler S., Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy., Cell Death Dis. 2019 Apr 3;10(4):302.
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Other

Kang L, Li C, Yang Q, Sutherlin L, Wang L, Chen Z, Becker KV, Huo N, Qiu Y, Engle JW, Wang R, He C, Jiang D, Xu X, Cai W., (64)Cu-labeled daratumumab F(ab')(2) fragment enables early visualization of CD38-positive lymphoma, Eur J Nucl Med Mol Imaging. 2021 Oct 22. doi: 10.1007/s00259-021-05593-9. Online ahead of print.
Hoegger MJ, Longtine MS, Shim K, Wahl RL., Bioluminescent Tumor Signal Is Mouse Strain and Pelt Color Dependent: Experience in a Disseminated Lymphoma Model, Mol Imaging Biol. 2021 Oct;23(5):697-702. doi: 10.1007/s11307-021-01594-0. Epub 2021 Apr 8.
Kang L, Li C, Rosenkrans ZT, Huo N, Chen Z, Ehlerding EB, Huo Y, Ferreira CA, Barnhart TE, Engle JW, Wang R, Jiang D, Xu X, Cai W., CD38-Targeted Theranostics of Lymphoma with (89)Zr/(177)Lu-Labeled Daratumumab, Adv Sci (Weinh). 2021 Mar 15;8(10):2001879. doi: 10.1002/advs.202001879. eCollection 2021 May.
Ahmad F, Hyvärinen A, Pirinen A, Olsson V, Rummukainen J, Immonen A, Närväinen J, Tuunanen P, Liimatainen T, Kärkkäinen V, Koistinaho J, Ylä-?erttuala S., Lentivirus vector?mediated genetic manipulation of oncogenic pathways induces tumor formation in rabbit brain, Mol Med Rep. 2021 Jun;23(6):422. doi: 10.3892/mmr.2021.12061. Epub 2021 Apr 13.
Kang L, Li C, Rosenkrans ZT, Engle JW, Wang R, Jiang D, Xu X, Cai W., Noninvasive Evaluation of CD20 Expression Using (64)Cu-Labeled F(ab')(2) Fragments of Obinutuzumab in Lymphoma, J Nucl Med. 2021 Mar;62(3):372-378. doi: 10.2967/jnumed.120.246595. Epub 2020 Aug 21.
Novy Z, Janousek J, Barta P, Petrik M, Hajduch M, Trejtnar F., Preclinical evaluation of anti-VEGFR2 monoclonal antibody ramucirumab labelled with zirconium-89 for tumour imaging, J Labelled Comp Radiopharm. 2021 Jun 15;64(7):262-270. doi: 10.1002/jlcr.3909. Epub 2021 Apr 14.
Liu H, Wang Z, He J, Li Z, Gao JY, Liu R, Lin P, Yang J., Promotion of Bone Lesions Through the Myeloma Integrin ?6-Mediated Osteolytic Signaling, Front Oncol. 2021 Jun 3;11:692190. doi: 10.3389/fonc.2021.692190. eCollection 2021.
Perrone F, Craparo EF, Cemazar M, Kamensek U, Drago SE, Dapas B, Scaggiante B, Zanconati F, Bonazza D, Grassi M, Truong N, Pozzato G, Farra R, Cavallaro G, Grassi G., Targeted delivery of siRNAs against hepatocellular carcinoma-related genes by a galactosylated polyaspartamide copolymer, J Control Release. 2021 Feb 10;330:1132-1151. doi: 10.1016/j.jconrel.2020.11.020. Epub 2020 Nov 17.
Sami E, Bogan D, Molinolo A, Koziol J, ElShamy WM., The molecular underpinning of geminin-overexpressing triple-negative breast cancer cells homing specifically to lungs, Cancer Gene Ther. 2021 Mar 15. doi: 10.1038/s41417-021-00311-x. Online ahead of print.
Reissig F, Bauer D, Zarschler K, Novy Z, Bendova K, Ludik MC, Kopka K, Pietzsch HJ, Petrik M, Mamat C., Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA-A Proof of Concept Study, Cancers (Basel). 2021 Apr 20;13(8):1974. doi: 10.3390/cancers13081974.

Transplantation

Wang, Y. Y., Chatzistavrou, X., Faulk, D., Badylak, S., Zheng, L., Papagerakis, S., . . . Papagerakis, P. (2015), Biological and bactericidal properties of ag-doped bioactive glass in a natural extracellular matrix hydrogel with potential application in dentistry., European Cells & Materials, 29, 342-355. doi:vol029a25 [pii]
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Dong, Qing; Wang, Yuanyuan; Mohabatpour, Fatemeh; Zheng, Li; Papagerakis, Silvana; Chen, Daniel; Papagerakis, Petros, Dental Pulp Stem Cells: Isolation, Characterization, Expansion, and Odontoblast Differentiation for Tissue Engineering., Methods in molecular biology (Clifton, N.J.) Vol.1922, 2019
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Tumor cell growth

Shen T, Dong B, Meng Y, Moore DD, Yang F., A COP1-GATA2 axis suppresses AR signaling and prostate cancer, Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2205350119. doi: 10.1073/pnas.2205350119. Epub 2022 Oct 17.
Ning S, Zhao J, Lombard AP, D'Abronzo LS, Leslie AR, Sharifi M, Lou W, Liu C, Yang JC, Evans CP, Corey E, Chen HW, Yu A, Ghosh PM, Gao AC., Activation of neural lineage networks and ARHGEF2 in enzalutamide-resistant and neuroendocrine prostate cancer and association with patient outcomes, Commun Med (Lond). 2022 Sep 21;2:118. doi: 10.1038/s43856-022-00182-9. eCollection 2022.
Gómez-Muñoz, M. A., Aguilar-Morante, D., Colmenero-Repiso, A., Amador-Álvarez, A., Ojeda-Puertas, M., Cordero Varela, J. A., Rodríguez-Prieto, I., Pardal, R., & Vega, F. M., Analysis of Serial Neuroblastoma PDX Passages in Mice Allows the Identification of New Mediators of Neuroblastoma Aggressiveness., Int J Mol Sci. 2023 Jan 13;24(2). pii: 1590. doi: 10.3390/ijms24021590.
Ning S, Liu C, Lou W, Yang JC, Lombard AP, D'Abronzo LS, Batra N, Yu AM, Leslie AR, Sharifi M, Evans CP, Gao AC., Bioengineered BERA-Wnt5a siRNA Targeting Wnt5a/FZD2 Signaling Suppresses Advanced Prostate Cancer Tumor Growth and Enhances Enzalutamide Treatment, Mol Cancer Ther. 2022 Oct 7;21(10):1594-1607. doi: 10.1158/1535-7163.MCT-22-0216.
Kakarla M, ChallaSivaKanaka S, Dufficy MF, Gil V, Filipovich Y, Vickman R, Crawford SE, Hayward SW, Franco OE., Ephrin B Activate Src Family Kinases in Fibroblasts Inducing Stromal Remodeling in Prostate Cancer, Cancers (Basel). 2022 May 9;14(9):2336. doi: 10.3390/cancers14092336.
Wang F, Liu Y, Qiu W, Shum E, Feng M, Zhao D, Zheng D, Borczuk A, Cheng H, Halmos B., Functional Analysis of MET Exon 14 Skipping Alteration in Cancer Invasion and Metastatic Dissemination, Cancer Res. 2022 Apr 1;82(7):1365-1379. doi: 10.1158/0008-5472.CAN-21-1327.
McAloney CA, Makkawi R, Budhathoki Y, Cannon MV, Franz EM, Gross AC, Cam M, Vetter TA, Duhen R, Davies AE, Roberts RD., Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization., Cell Oncol (Dordr). 2023 Sep 7. doi: 10.1007/s13402-023-00867-w. [Epub ahead of print]
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Tumor growth

Alagpulinsa, D. A., Ayyadevara, S., Yaccoby, S., & Shmookler Reis, R. J. (2016)., A cyclin-dependent kinase inhibitor, dinaciclib, impairs homologous recombination and sensitizes multiple myeloma cells to PARP inhibition., Molecular Cancer Therapeutics, 15(2), 241-250. doi:10.1158/1535-7163.MCT-15-0660 [doi]
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