BALB/c inbred mice

Related publications

Aging

Bolles, M., Deming, D., Long, K., Agnihothram, S., Whitmore, A., Ferris, M., . . . Baric, R. S. (2011)., A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge, Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]

Corsetti, G., Pasini, E., Romano, C., Calvani, R., Picca, A., Marzetti, E., . . . Dioguardi, F. S. (2018)., Body weight loss and tissue wasting in late middle-aged mice on slightly imbalanced Essential/Non-essential amino acids diet., Frontiers in Medicine, 5, 136. doi:10.3389/fmed.2018.00136 [doi]

Rockx, B., Baas, T., Zornetzer, G. A., Haagmans, B., Sheahan, T., Frieman, M., . . . Katze, M. G. (2009), Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection, Journal of Virology, 83(14), 7062-7074. doi:10.1128/JVI.00127-09 [doi]

Barone, R., Macaluso, F., Catanese, P., Marino Gammazza, A., Rizzuto, L., Marozzi, P., . . . Di Felice, V. (2013)., Endurance exercise and conjugated linoleic acid (CLA) supplementation up-regulate CYP17A1 and stimulate testosterone biosynthesis, PloS One, 8(11), e79686. doi:10.1371/journal.pone.0079686 [doi]

Clayton, E. H., Garbow, J. R., & Bayly, P. V. (2011)., Frequency-dependent viscoelastic parameters of mouse brain tissue estimated by MR elastography, Physics in Medicine and Biology, 56(8), 2391-2406. doi:10.1088/0031-9155/56/8/005 [doi]

Cayatte, C., Snell Bennett, A., Rajani, G. M., Hostetler, L., Maynard, S. K., Lazzaro, M., . . . Schneider-Ohrum, K. (2017)., Inferior immunogenicity and efficacy of respiratory syncytial virus fusion protein-based subunit vaccine candidates in aged versus young mice., PloS One, 12(11), e0188708. doi:10.1371/journal.pone.0188708 [doi]

Grizenkova, J., Akhtar, S., Brandner, S., Collinge, J., & Lloyd, S. E. (2014), Microglial Cx3cr1 knockout reduces prion disease incubation time in mice., BMC Neuroscience, 15, 44-2202-15-44. doi:10.1186/1471-2202-15-44 [doi]

Antibody production

Rijal P, Wang BB, Tan TK, Schimanski L, Janesch P, Dong T, McCauley JW, Daniels RS, Townsend AR, Huang KA., Broadly Inhibiting Antineuraminidase Monoclonal Antibodies Induced by Trivalent Influenza Vaccine and H7N9 Infection in Humans, J Virol. 2020 Jan 31;94(4):e01182-19. doi: 10.1128/JVI.01182-19. Print 2020 Jan 31.

McKitrick TR, Goth CK, Rosenberg CS, Nakahara H, Heimburg-Molinaro J, McQuillan AM, Falco R, Rivers NJ, Herrin BR, Cooper MD, Cummings RD., Development of smart anti-glycan reagents using immunized lampreys, Commun Biol. 2020 Feb 28;3(1):91. doi: 10.1038/s42003-020-0819-2.

Boyoglu-Barnum S, Hutchinson GB, Boyington JC, Moin SM, Gillespie RA, Tsybovsky Y, Stephens T, Vaile JR, Lederhofer J, Corbett KS, Fisher BE, Yassine HM, Andrews SF, Crank MC, McDermott AB, Mascola JR, Graham BS, Kanekiyo M., Glycan repositioning of influenza hemagglutinin stem facilitates the elicitation of protective cross-group antibody responses, Nat Commun. 2020 Feb 7;11(1):791. doi: 10.1038/s41467-020-14579-4.

Hemon MF, Lambert NC, Arnoux F, Roudier J, Auger I., PAD4 Immunization Triggers Anti-Citrullinated Peptide Antibodies in Normal Mice: Analysis With Peptide Arrays, Front Immunol. 2022 Mar 31;13:840035. doi: 10.3389/fimmu.2022.840035. eCollection 2022.

Cardiovascular

Bruce, A. C., & Peirce, S. M. (2012)., Exogenous thrombin delivery promotes collateral capillary arterialization and tissue reperfusion in the murine spinotrapezius muscle ischemia model., Microcirculation (New York, N.Y.: 1994), 19(2), 143-154. doi:10.1111/j.1549-8719.2011.00138.x [doi]

Schiviz, A., Magirr, D., Leidenmuhler, P., Schuster, M., Muchitsch, E. M., Hollriegl, W., & Subcommittee on Animal Models. (2014)., Influence of genetic background on bleeding phenotype in the tail-tip bleeding model and recommendations for standardization: Communication from the SSC of the ISTH., Journal of Thrombosis and Haemostasis : JTH, 12(11), 1940-1942. doi:10.1111/jth.12700 [doi]

Kolosowska N, Gotkiewicz M, Dhungana H, Giudice L, Giugno R, Box D, Huuskonen MT, Korhonen P, Scoyni F, Kanninen KM, YlĂ¤-Herttuala S, Turunen TA, Turunen MP, Koistinaho J, Malm T., Intracerebral overexpression of miR-669c is protective in mouse ischemic stroke model by targeting MyD88 and inducing alternative microglial/macrophage activation, J Neuroinflammation. 2020 Jun 19;17(1):194. doi: 10.1186/s12974-020-01870-w.

Stohr, R., Mavilio, M., Marino, A., Casagrande, V., Kappel, B., Mollmann, J., . . . Federici, M. (2015), ITCH modulates SIRT6 and SREBP2 to influence lipid metabolism and atherosclerosis in ApoE null mice., Scientific Reports, 5, 9023. doi:10.1038/srep09023 [doi]

De Hoog, V. C., Timmers, L., Van Duijvenvoorde, A., De Jager, S. C., Van Middelaar, B. J., Smeets, M. B., . . . De Kleijn, D. P. (2014), Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury, Cardiovascular Research, 103(4), 521-529. doi:10.1093/cvr/cvu153 [doi]

Turner, J. K., McAllister, M. M., Xu, J. L., & Tapping, R. I. (2008)., The resistance of BALB/cJ mice to yersinia pestis maps to the major histocompatibility complex of chromosome 17., Infection and Immunity, 76(9), 4092-4099. doi:10.1128/IAI.00488-08 [doi]

Antonioni A, Dimauro I, Fantini C, Barone R, Macaluso F, Di Felice V, Caporossi D., ÎąB-crystallin response to a pro-oxidant non-cytotoxic environment in murine cardiac cells: An "in vitro" and "in vivo" study, Free Radic Biol Med. 2020 May 20;152:301-312. doi: 10.1016/j.freeradbiomed.2020.03.013. Epub 2020 Mar 26.

COVID-19

Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al., A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses, bioRxiv 2020.08.31.275701; doi: https://doi.org/10.1101/2020.08.31.275701

Dinnon KH 3rd, Leist SR, Schäfer A, Edwards CE, Martinez DR, Montgomery SA, West A, Yount BL Jr, Hou YJ, Adams LE, Gully KL, Brown AJ, Huang E, Bryant MD, Choong IC, Glenn JS, Gralinski LE, Sheahan TP, Baric RS., A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures, Nature. 2020 Oct;586(7830):560-566. doi: 10.1038/s41586-020-2708-8. Epub 2020 Aug 27.

Leist SR, Dinnon KH 3rd, Schäfer A, Tse LV, Okuda K, Hou YJ, West A, Edwards CE, Sanders W, Fritch EJ, Gully KL, Scobey T, Brown AJ, Sheahan TP, Moorman NJ, Boucher RC, Gralinski LE, Montgomery SA, Baric RS., A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice, Cell. 2020 Nov 12;183(4):1070-1085.e12. doi: 10.1016/j.cell.2020.09.050. Epub 2020 Sep 23.

Schäfer A, Muecksch F, Lorenzi JCC, Leist SR, Cipolla M, Bournazos S, Schmidt F, Maison RM, Gazumyan A, Martinez DR, Baric RS, Robbiani DF, Hatziioannou T, Ravetch JV, Bieniasz PD, Bowen RA, Nussenzweig MC, Sheahan TP., Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo, J Exp Med. 2021 Mar 1;218(3):e20201993. doi: 10.1084/jem.20201993.

van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato V, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, PĂŠrez-PĂŠrez L, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ., ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques, bioRxiv. 2020 May 13:2020.05.13.093195. doi: 10.1101/2020.05.13.093195. Preprint.

van Doremalen N, Lambe T, Spencer A, Belij-Rammerstorfer S, Purushotham JN, Port JR, Avanzato VA, Bushmaker T, Flaxman A, Ulaszewska M, Feldmann F, Allen ER, Sharpe H, Schulz J, Holbrook M, Okumura A, Meade-White K, PĂŠrez-PĂŠrez L, Edwards NJ, Wright D, Bissett C, Gilbride C, Williamson BN, Rosenke R, Long D, Ishwarbhai A, Kailath R, Rose L, Morris S, Powers C, Lovaglio J, Hanley PW, Scott D, Saturday G, de Wit E, Gilbert SC, Munster VJ., ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques, Nature. 2020 Oct;586(7830):578-582. doi: 10.1038/s41586-020-2608-y. Epub 2020 Jul 30.

Menachery VD, Gralinski LE, Mitchell HD, Dinnon KH 3rd, Leist SR, Yount BL Jr, McAnarney ET, Graham RL, Waters KM, Baric RS., Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines, J Virol. 2018 Aug 16;92(17):e00710-18. doi: 10.1128/JVI.00710-18. Print 2018 Sep 1.

Graham SP, McLean RK, Spencer AJ, Belij-Rammerstorfer S, Wright D, Ulaszewska M, Edwards JC, Hayes JWP, Martini V, Thakur N, Conceicao C, Dietrich I, Shelton H, Waters R, Ludi A, Wilsden G, Browning C, Bialy D, Bhat S, Stevenson-Leggett P, Hollinghurst P, Gilbride C, Pulido D, Moffat K, Sharpe H, Allen E, Mioulet V, Chiu C, Newman J, Asfor AS, Burman A, Crossley S, Huo J, Owens RJ, Carroll M, Hammond JA, Tchilian E, Bailey D, Charleston B, Gilbert SC, Tuthill TJ, Lambe T., Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19, NPJ Vaccines. 2020 Jul 27;5:69. doi: 10.1038/s41541-020-00221-3. eCollection 2020.

Li W, Schäfer A, Kulkarni SS, Liu X, Martinez DR, Chen C, Sun Z, Leist SR, Drelich A, Zhang L, Ura ML, Berezuk A, Chittori S, Leopold K, Mannar D, Srivastava SS, Zhu X, Peterson EC, Tseng CT, Mellors JW, Falzarano D, Subramaniam S, Baric RS, Dimitrov DS., High Potency of a Bivalent Human V(H) Domain in SARS-CoV-2 Animal Models, Cell. 2020 Oct 15;183(2):429-441.e16. doi: 10.1016/j.cell.2020.09.007. Epub 2020 Sep 4.

Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno Correia, David Peterhoff, Ralf Wagner, View ORCID ProfileRoman Jerala, Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein, bioRxiv 2020.08.28.244269; doi: https://doi.org/10.1101/2020.08.28.244269

Capone S, Raggioli A, Gentile M, et al., Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19, bioRxiv 2020.10.22.349951; doi: https://doi.org/10.1101/2020.10.22.349951

Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, SchĂ¤fer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE Jr., Potently neutralizing and protective human antibodies against SARS-CoV-2, Nature. 2020 Aug;584(7821):443-449. doi: 10.1038/s41586-020-2548-6. Epub 2020 Jul 15.

Li W, Chen C, Drelich A, Martinez DR, Gralinski LE, Sun Z, SchĂ¤fer A, Kulkarni SS, Liu X, Leist SR, Zhelev DV, Zhang L, Kim YJ, Peterson EC, Conard A, Mellors JW, Tseng CK, Falzarano D, Baric RS, Dimitrov DS., Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection, Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29832-29838. doi: 10.1073/pnas.2010197117. Epub 2020 Nov 2.

Mohsen MO, Balke I, Zinkhan S, Zeltina V, Liu X, Chang X, Krenger PS, Plattner K, Gharailoo Z, Vogt AS, Augusto G, Zwicker M, Roongta S, Rothen DA, Josi R, Costa JJD, Sobczak JM, Nonic A, Brand LA, Nuss K, Martina B, Speiser DE, et al., A scalable and highly immunogenic virus-like particle-based vaccine against SARS-CoV-2., Allergy. 2021 Sep 8. doi: 10.1111/all.15080. [Epub ahead of print]

Liu X, Chang X, Rothen D, Derveni M, Krenger P, Roongta S, Wright E, Vogel M, Tars K, Mohsen MO, Bachmann MF., AP205 VLPs Based on Dimerized Capsid Proteins Accommodate RBM Domain of SARS-CoV-2 and Serve as an Attractive Vaccine Candidate., Vaccines (Basel). 2021 Apr 19;9(4). pii: 403. doi: 10.3390/vaccines9040403.

Hsieh CL, Werner AP, Leist SR, Stevens LJ, Falconer E, Goldsmith JA, Chou CW, Abiona OM, West A, Westendorf K, Muthuraman K, Fritch EJ, Dinnon KH 3rd, SchĂ¤fer A, Denison MR, Chappell JD, Baric RS, Graham BS, Corbett KS, McLellan JS., Stabilized coronavirus spike stem elicits a broadly protective antibody., Cell Rep. 2021 Nov 2;37(5):109929. doi: 10.1016/j.celrep.2021.109929. Epub 2021 Oct 16.

Spencer AJ, Morris S, Ulaszewska M, Powers C, Kailath R, Bissett C, Truby A, Thakur N, Newman J, Allen ER, Rudiansyah I, Liu C, Dejnirattisai W, Mongkolsapaya J, Davies H, Donnellan FR, Pulido D, Peacock TP, Barclay WS, Bright H, Ren K, Screaton G, McTamney P, Bailey D, Gilbert SC, Lambe T., The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies, EBioMedicine. 2022 Mar;77:103902. doi: 10.1016/j.ebiom.2022.103902. Epub 2022 Feb 26.

Kim K, Narasimhan M, Mahimainathan L, Zhang R, Araj E, Kim E, Tharpe W, Greenberg BM, Greenberg DE, Li QZ, Cheng CA, Sarode R, Malladi S, Muthukumar A., Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group, Front Immunol. 2022 Oct 26;13:1020165. doi: 10.3389/fimmu.2022.1020165

Du Y, Zhang S, Zhang Z, Miah KM, Wei P, Zhang L, Zhu Y, Li Z, Ye F, Gill DR, Hyde SC, Wang Y, Zhao J., Intranasal lentiviral vector-mediated antibody delivery confers reduction of SARS-CoV-2 infection in elderly and immunocompromised mice, Front Immunol. 2022 Apr 22;13:819058. doi: 10.3389/fimmu.2022.819058

Chang X, Liu X, Mohsen MO, Zeltins A, Martina B, Vogel M, Bachmann MF., Induction of Broadly Cross-Reactive Antibodies by Displaying Receptor Binding Domains of SARS-CoV-2 on Virus-like Particles, Vaccines (Basel). 2022 Feb 16;10(2):307. doi: 10.3390/vaccines10020307.

McCollum CR, Courtney CM, O'Connor NJ, Aunins TR, Ding Y, Jordan TX, Rogers KL, Brindley S, Brown JM, Nagpal P, Chatterjee A., Nanoligomers targeting human miRNA for the treatment of severe COVID-19 are safe and nontoxic in mice, ACS Biomater Sci Eng. 2022 Jul 11;8(7):3087-3106.

General studies

Kropp, K. A., Hsieh, W. Y., Isern, E., Forster, T., Krause, E., Brune, W., . . . Ghazal, P. (2015)., A temporal gate for viral enhancers to co-opt toll-like-receptor transcriptional activation pathways upon acute infection., PLoS Pathogens, 11(4), e1004737. doi:10.1371/journal.ppat.1004737 [doi]

Barone, R., Rappa, F., Macaluso, F., Caruso Bavisotto, C., Sangiorgi, C., Di Paola, G., . . . Marino Gammazza, A. (2016), Alcoholic liver disease: A mouse model reveals protection by lactobacillus fermentum., Clinical and Translational Gastroenterology, 7, e138. doi:10.1038/ctg.2015.66 [doi]

Pérez P, Marín MQ, Lázaro-Frías A, Sorzano CÓS, Di Pilato M, Gómez CE, Esteban M, García-Arriaza J., An MVA Vector Expressing HIV-1 Envelope under the Control of a Potent Vaccinia Virus Promoter as a Promising Strategy in HIV/AIDS Vaccine Design, Vaccines Vol.7, 2019

Rubio-Solsona, E., Marti, S., Vilchez, J. J., Palau, F., & Hoenicka, J. (2018)., ANKK1 is found in myogenic precursors and muscle fibers subtypes with glycolytic metabolism, PloS One, 13(5), e0197254. doi:10.1371/journal.pone.0197254 [doi]

Birkus, Gabriel; Snyder, Chelsea; Jordan, Robert; Kobayashi, Tetsuya; Dick, Ryan; Puscau, Vlad; Li, Li; Ramirez, Ricardo; Willkom, Madeleine; Morikawa, Yoshida; Delaney Iv, William E; Schmitz, Uli, Anti-HBV activity of retinoid drugs in vitro versus in vivo, Antiviral research Vol.169, 2019

Jansen van Vuren, P., Tiemessen, C. T., & Paweska, J. T. (2011)., Anti-nucleocapsid protein immune responses counteract pathogenic effects of rift valley fever virus infection in mice., PloS One, 6(9), e25027. doi:10.1371/journal.pone.0025027 [doi]

Heinla, I., Ahlgren, J., Vasar, E., & Voikar, V. (2018), Behavioural characterization of C57BL/6N and BALB/c female mice in social home cage - effect of mixed housing in complex environment., Physiology & Behavior, 188, 32-41. doi:S0031-9384(18)30032-5 [pii]

Calabrese, G., Giuffrida, R., Forte, S., Salvatorelli, L., Fabbi, C., Figallo, E., . . . Gulino, R. (2016)., Bone augmentation after ectopic implantation of a cell-free collagen-hydroxyapatite scaffold in the mouse., Scientific Reports, 6, 36399. doi:10.1038/srep36399 [doi]

HeinimĂ¤ki, Suvi; Hankaniemi, Minna M; Sioofy-Khojine, Amir-Babak; Laitinen, Olli H; HyĂśty, Heikki; HytĂśnen, Vesa P; Vesikari, Timo; Blazevic, Vesna, Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus., Vaccine Vol.37, 2019

Rancilio, N. J., Dahl, S., Athanasiadi, I., & Perez-Torres, C. J. (2017)., Design, construction, and in vivo feasibility of a positioning device for irradiation of mice brains using a clinical linear accelerator and intensity modulated radiation therapy., International Journal of Radiation Biology, 93(12), 1321-1326. doi:10.1080/09553002.2017.1387305 [doi]

Haste, L., Hulland, K., Bolton, S., Yesilkaya, H., McKechnie, K., & Andrew, P. W. (2014)., Development and characterization of a long-term murine model of streptococcus pneumoniae infection of the lower airways., Infection and Immunity, 82(8), 3289-3298. doi:10.1128/IAI.01623-14 [doi]

Desroches-Castan, AgnĂ¨s; Tillet, Emmanuelle; Ricard, Nicolas; OuarnĂŠ, Marie; Mallet, Christine; Feige, Jean-Jacques; Bailly, Sabine, Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice., Cells Vol.8, 2019

Brickman, T. J., Hanawa, T., Anderson, M. T., Suhadolc, R. J., & Armstrong, S. K. (2008)., Differential expression of bordetella pertussis iron transport system genes during infection., Molecular Microbiology, 70(1), 3-14. doi:10.1111/j.1365-2958.2008.06333.x [doi]

Azcarate, I. G., Marin-Garcia, P., Kamali, A. N., Perez-Benavente, S., Puyet, A., Diez, A., & Bautista, J. M. (2014)., Differential immune response associated to malaria outcome is detectable in peripheral blood following plasmodium yoelii infection in mice., PloS One, 9(1), e85664. doi:10.1371/journal.pone.0085664 [doi]

Browne, C. A., O'Brien, F. E., Connor, T. J., Dinan, T. G., & Cryan, J. F. (2012)., Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: Effects of stress., Neuroscience, 225, 237-248. doi:10.1016/j.neuroscience.2012.08.031 [doi]

Stock, M., Kirchner, B., Waibler, D., Cowley, D. E., Pfaffl, M. W., & Kuehn, R. (2012), Effect of magnetic stimulation on the gene expression profile of in vitro cultured neural cells., Neuroscience Letters, 526(2), 122-127. doi:10.1016/j.neulet.2012.08.024 [doi]

Christie, R. D., Marcus, E. C., Wagner, A. M., & Besselsen, D. G. (2010)., Experimental infection of mice with hamster parvovirus: Evidence for interspecies transmission of mouse parvovirus 3., Comparative Medicine, 60(2), 123-129.

Romero, A., Gomez, O., Terrado, J., & Mesonero, J. E. (2009)., Expression of GLUT8 in mouse intestine: Identification of alternative spliced variants, Journal of Cellular Biochemistry, 106(6), 1068-1078. doi:10.1002/jcb.22090 [doi]

PlĂśhn, Svenja; Hose, Matthias; SchlĂźter, Anke; Michel, Lars; Diaz-Cano, Salvador; Hendgen-Cotta, Ulrike B; Banga, Jasvinder Paul; Bechrakis, Nikolaos E; Hansen, Wiebke; Eckstein, Anja; Berchner-Pfannschmidt, Utta;, Fingolimod Improves the Outcome of Experimental Graves Disease and Associated Orbitopathy by Modulating the Autoimmune Response to the Thyroid-Stimulating Hormone Receptor, Thyroid : official journal of the American Thyroid Association Vol.29, 2019

Hankaniemi, Minna M; Stone, Virginia M; Andrejeff, Tanja; HeinimĂ¤ki, Suvi; Sioofy-Khojine, Amir-Babak; MarjomĂ¤ki, Varpu; HyĂśty, Heikki; Blazevic, Vesna; FlodstrĂśm-Tullberg, Malin; HytĂśnen, Vesa P; Laitinen, Olli H;, Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine., Antiviral research Vol.171, 2019

Levison, S. E., Fisher, P., Hankinson, J., Zeef, L., Eyre, S., Ollier, W. E., . . . Pennock, J. L. (2013)., Genetic analysis of the trichuris muris-induced model of colitis reveals QTL overlap and a novel gene cluster for establishing colonic inflammation., . BMC Genomics, 14, 127-2164-14-127. doi:10.1186/1471-2164-14-127 [doi]

Jonczyk, M. S., Simon, M., Kumar, S., Fernandes, V. E., Sylvius, N., Mallon, A. M., . . . Andrew, P. W. (2014), Genetic factors regulating lung vasculature and immune cell functions associate with resistance to pneumococcal infection, PloS One, 9(3), e89831. doi:10.1371/journal.pone.0089831 [doi]

Masetti, G., Moshkelgosha, S., Kohling, H. L., Covelli, D., Banga, J. P., Berchner-Pfannschmidt, U., . . . INDIGO consortium. (2018)., Gut microbiota in experimental murine model of graves' orbitopathy established in different environments may modulate clinical presentation of disease., Microbiome, 6(1), 97-018-0478-4. doi:10.1186/s40168-018-0478-4 [doi]

Fercoq, Frédéric; Remion, Estelle; Frohberger, Stefan J; Vallarino-Lhermitte, Nathaly; Hoerauf, Achim; Le Quesne, John; Landmann, Frédéric; HĂźbner, Marc P; Carlin, Leo M; Martin, Coralie, IL-4 receptor dependent expansion of lung CD169+ macrophages in microfilaria-driven inflammation, PLoS neglected tropical diseases Vol.13, 2019

de Heusch M, Steenwinckel V, Cochez PM, Louahed J, Warnier G, Lemaire MM, Renauld JC, Dumoutier L., IL-9 exerts biological function on antigen-experienced murine TÂ cells and exacerbates colitis induced by adoptive transfer, Eur J Immunol. 2020 Jul;50(7):1034-1043. doi: 10.1002/eji.201948430. Epub 2020 Mar 18.

Ruiz-Manzano, Rocío Alejandra; Hernández-Cervantes, Rosalía; Del Río-Araiza, Víctor Hugo; Palacios-Arreola, Margarita Isabel; Nava-Castro, Karen Elizabeth; Morales-Montor, Jorge, Immune response to chronic Toxocara canis infection in a mice model., Parasite immunology Vol.41, 2019

Tamminen, Kirsi; Malm, Maria; Vesikari, Timo; Blazevic, Vesna;, Immunological Cross-Reactivity of an Ancestral and the Most Recent Pandemic Norovirus GII.4 Variant., Viruses Vol.11, 2019

Korhonen, P., Kanninen, K. M., Lehtonen, S., Lemarchant, S., Puttonen, K. A., Oksanen, M., . . . Malm, T. (2015), Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation, Brain, Behavior, and Immunity, doi:S0889-1591(15)00166-X [pii]

Calabrese, G., Gulino, R., Giuffrida, R., Forte, S., Figallo, E., Fabbi, C., . . . Parenti, R. (2017)., In vivo evaluation of biocompatibility and chondrogenic potential of a cell-free collagen-based scaffold., Frontiers in Physiology, 8, 984. doi:10.3389/fphys.2017.00984 [doi]

Even, P. C., & Blais, A. (2016)., Increased cost of motor activity and heat transfer between non-shivering thermogenesis, motor activity, and thermic effect of feeding in mice housed at room temperature - implications in pre-clinical studies., Frontiers in Nutrition, 3, 43. doi:10.3389/fnut.2016.00043 [doi]

Brickman, T. J., Suhadolc, R. J., & Armstrong, S. K. (2015)., Interspecies variations in bordetella catecholamine receptor gene regulation and function., Infection and Immunity, 83(12), 4639-4652. doi:10.1128/IAI.00787-15 [doi]

Spacova, I; Petrova, M I; Fremau, A; Pollaris, L; Vanoirbeek, J; Ceuppens, J L; Seys, S; Lebeer, S;, Intranasal administration of probiotic Lactobacillus rhamnosus GG prevents birch pollen-induced allergic asthma in a murine model. Allergy, Allergy Vol.74, 2019

Kraan, H., Soema, P., Amorij, J. P., & Kersten, G. (2017)., Intranasal and sublingual delivery of inactivated polio vaccine., Vaccine, 35(20), 2647-2653. doi:S0264-410X(17)30442-5 [pii]

Spacova I, Van Beeck W, Seys S, Devos F, Vanoirbeek J, Vanderleyden J, Ceuppens J, Petrova M, Lebeer S., Lactobacillus rhamnosus probiotic prevents airway function deterioration and promotes gut microbiome resilience in a murine asthma model, Gut Microbes. 2020 Nov 1;11(6):1729-1744. doi: 10.1080/19490976.2020.1766345. Epub 2020 Jun 10.

Kraus, P., Xing, X., Lim, S. L., Fun, M. E., Sivakamasundari, V., Yap, S. P., . . . Lufkin, T. (2012), Lufkin, T. (2012). Mouse strain specific gene expression differences for illumina microarray expression profiling in embryos, BMC Research Notes, 5, 232-0500-5-232. doi:10.1186/1756-0500-5-232 [doi]

Vono, Maria; Eberhardt, Christiane Sigrid; Auderset, Floriane; Mastelic-Gavillet, Beatris; Lemeille, Sylvain; Christensen, Dennis; Andersen, Peter; Lambert, Paul-Henri; Siegrist, Claire-Anne;, Maternal Antibodies Inhibit Neonatal and Infant Responses to Vaccination by Shaping the Early-Life B Cell Repertoire within Germinal Centers, Cell reports Vol.28, 2019

Samaniego, R., Estecha, A., Relloso, M., Longo, N., Escat, J. L., Longo-Imedio, I., . . . Sanchez-Mateos, P. (2013), Mesenchymal contribution to recruitment, infiltration, and positioning of leukocytes in human melanoma tissues., The Journal of Investigative Dermatology, 133(9), 2255-2264. doi:10.1038/jid.2013.88 [doi]

Rubin, R. L. (2017)., Mice housed at elevated vivarium temperatures display enhanced T-cell response and survival to francisella tularensis., Comparative Medicine, 67(6), 491-497.

Matusiak, N., van Waarde, A., Rozeveld, D., van Oosterhout, A. J., Heijink, I. H., Castelli, R., . . . Elsinga, P. H. (2015)., MicroPET evaluation of a hydroxamate-based MMP inhibitor, [F]FB-ML5, in a mouse model of cigarette smoke-induced acute airway inflammation., Molecular Imaging and Biology : MIB : The Official Publication of the Academy of Molecular Imaging, doi:10.1007/s11307-015-0847-3 [doi]

Mlera, L., Meade-White, K., Saturday, G., Scott, D., & Bloom, M. E. (2017)., Modeling powassan virus infection in peromyscus leucopus, a natural host., PLoS Neglected Tropical Diseases, 11(1), e0005346. doi:10.1371/journal.pntd.0005346 [doi]

Gouveia, K., & Hurst, J. L. (2017)., Optimising reliability of mouse performance in behavioural testing: The major role of non-aversive handling., Scientific Reports, 7, 44999. doi:10.1038/srep44999 [doi]

Kolosowska, Natalia; Keuters, Meike H; Wojciechowski, Sara; Keksa-Goldsteine, Velta; Laine, Mika; Malm, Tarja; Goldsteins, Gundars; Koistinaho, Jari; Dhungana, Hiramani, Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke., Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics Vol.37, 2019

Draijer, C., Boorsma, C. E., Reker-Smit, C., Post, E., Poelstra, K., & Melgert, B. N. (2016), PGE2-treated macrophages inhibit development of allergic lung inflammation in mice., Journal of Leukocyte Biology, 100(1), 95-102. doi:10.1189/jlb.3MAB1115-505R [doi]

Santio, N. M., Eerola, S. K., Paatero, I., Yli-Kauhaluoma, J., Anizon, F., Moreau, P., . . . Koskinen, P. J. (2015), Pim kinases promote migration and metastatic growth of prostate cancer xenografts, PloS One, 10(6), e0130340. doi:10.1371/journal.pone.0130340 [doi]

Kirchner, J., Hackbarth, H., Stelzer, H. D., & Tsai, P. P. (2012)., Preferences of group-housed female mice regarding structure of softwood bedding., Laboratory Animals, 46(2), 95-100. doi:10.1258/la.2011.010173 [doi]

Grosso-Becerra, M. V., Santos-Medellin, C., Gonzalez-Valdez, A., Mendez, J. L., Delgado, G., Morales-Espinosa, R., . . . Soberon-Chavez, G. (2014), Pseudomonas aeruginosa clinical and environmental isolates constitute a single population with high phenotypic diversity., BMC Genomics, 15, 318-2164-15-318. doi:10.1186/1471-2164-15-318 [doi]

Rolot, Marion; M Dougall, Annette; Javaux, Justine; Lallemand, François; Machiels, Bénédicte; Martinive, Philippe; Dewals, Benjamin G;, Recruitment of hepatic macrophages from monocytes is independent of IL-4R?? but is associated with ablation of resident macrophages in schistosomiasis., European journal of immunology Vol.49, 2019

Hofmann, S., Hilbe, M., Fajardo, R. J., Hagenmuller, H., Nuss, K., Arras, M., . . . Meinel, L. (2013)., Remodeling of tissue-engineered bone structures in vivo., . European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 85(1), 119-129. doi:10.1016/j.ejpb.2013.02.011 [doi]

Percie du Sert N, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC, Dirnagl U, Emerson M, Garner P, Holgate ST, Howells DW, Hurst V, Karp NA, Lazic SE, Lidster K, MacCallum CJ, Macleod M, Pearl EJ, Petersen OH, Rawle F, Reynolds P, Rooney K, Sena ES, Silberberg SD, Steckler T, Würbel H., Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0, PLoS Biol. 2020 Jul 14;18(7):e3000411. doi: 10.1371/journal.pbio.3000411. eCollection 2020 Jul.

Wirz, A., Mandillo, S., D'Amato, F. R., Giuliani, A., & Riviello, M. C. (2015), Response, use and habituation to a mouse house in C57BL/6J and BALB/c mice., Experimental Animals / Japanese Association for Laboratory Animal Science, 64(3), 281-293. doi:10.1538/expanim.14-0104 [doi]

Malm, Maria; Diessner, André; Tamminen, Kirsi; Liebscher, Markus; Vesikari, Timo; Blazevic, Vesna;, Rotavirus VP6 as an Adjuvant for Bivalent Norovirus Vaccine Produced in Nicotiana benthamiana., Pharmaceutics Vol.11, 2019

Ohia-Nwoko, O., Haile, C. N., & Kosten, T. A. (2017)., Sex differences in the acute locomotor response to methamphetamine in BALB/c mice., Behavioural Brain Research, 327, 94-97. doi:S0166-4328(16)31259-1 [pii]

Nava-Castro, Karen Elizabeth; Solleiro-Villavicencio, Helena; Río-Araiza, Víctor Hugo Del; Segovia-Mendoza, Mariana; Pérez-Torres, Armando; Morales-Montor, Jorge, Sex-associated protective effect of early bisphenol-A exposure during enteric infection with Trichinella spiralis in mice, PloS one Vol.14, 2019

van den Berg, W. E., Lamballais, S., & Kushner, S. A. (2015)., Sex-specific mechanism of social hierarchy in mice., Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 40(6), 1364-1372. doi:10.1038/npp.2014.319 [doi]

Hogenkamp, A., Thijssen, S., van Vlies, N., & Garssen, J. (2015)., Supplementing pregnant mice with a specific mixture of nondigestible oligosaccharides reduces symptoms of allergic asthma in male offspring., The Journal of Nutrition, 145(3), 640-646. doi:10.3945/jn.114.197707 [doi]

Kleiner, G., Celsi, F., Tricarico, P. M., Zacchigna, S., Crovella, S., & Marcuzzi, A. (2013)., Systemic and neuronal inflammatory markers in a mouse model of mevalonate kinase deficiency: A strain-comparative study., In Vivo (Athens, Greece), 27(6), 715-722. doi:27/6/715 [pii]

Milani C, Farina F, Botto L, Massimino L, Lonati E, Donzelli E, Ballarini E, Crippa L, Marmiroli P, Bulbarelli A, Palestini P., Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset, Int J Mol Sci. 2020 May 24;21(10):3699. doi: 10.3390/ijms21103699.

Neill, D. R., Fernandes, V. E., Wisby, L., Haynes, A. R., Ferreira, D. M., Laher, A., . . . Andrew, P. W. (2012)., T regulatory cells control susceptibility to invasive pneumococcal pneumonia in mice., PLoS Pathogens, 8(4), e1002660. doi:10.1371/journal.ppat.1002660 [doi]

Kemper, K., Rodermond, H., Colak, S., Grandela, C., & Medema, J. P. (2012)., Targeting colorectal cancer stem cells with inducible caspase-9, Apoptosis : An International Journal on Programmed Cell Death, 17(5), 528-537. doi:10.1007/s10495-011-0692-z [doi]

Isern, E., Gustems, M., Messerle, M., Borst, E., Ghazal, P., & Angulo, A. (2011)., The activator protein 1 binding motifs within the human cytomegalovirus major immediate-early enhancer are functionally redundant and act in a cooperative manner with the NF-{kappa}B sites during acute infection., Journal of Virology, 85(4), 1732-1746. doi:10.1128/JVI.01713-10 [doi]

Neill, D. R., Saint, G. L., Bricio-Moreno, L., Fothergill, J. L., Southern, K. W., Winstanley, C., . . . Flanagan, B. F. (2014)., The B lymphocyte differentiation factor (BAFF) is expressed in the airways of children with CF and in lungs of mice infected with pseudomonas aeruginosa, PloS One, 9(5), e95892. doi:10.1371/journal.pone.0095892 [doi]

Fernandes VE, Ercoli G, Bénard A, Brandl C, Fahnenstiel H, Müller-Winkler J, Weber GF, Denny P, Nitschke L, Andrew PW., The B-cell inhibitory receptor CD22 is a major factor in host resistance to Streptococcus pneumoniae infection, PLoS Pathog. 2020 Apr 23;16(4):e1008464. doi: 10.1371/journal.ppat.1008464. eCollection 2020 Apr.

Spencer, A. J., Longley, R. J., Gola, A., Ulaszewska, M., Lambe, T., & Hill, A. V. (2017)., The threshold of protection from liver-stage malaria relies on a fine balance between the number of infected hepatocytes and effector CD8(+) T cells present in the liver, Journal of Immunology (Baltimore, Md.: 1950), 198(5), 2006-2016. doi:10.4049/jimmunol.1601209 [doi]

Wong, S. H., Walker, J. A., Jolin, H. E., Drynan, L. F., Hams, E., Camelo, A., . . . McKenzie, A. N. (2012)., Transcription factor RORalpha is critical for nuocyte development., Nature Immunology, 13(3), 229-236. doi:10.1038/ni.2208 [doi]

Craig, M., Sadik, A. Y., Golubeva, Y. A., Tidhar, A., & Slauch, J. M. (2013), Twin-arginine translocation system (tat) mutants of salmonella are attenuated due to envelope defects, not respiratory defects., Molecular Microbiology, 89(5), 887-902. doi:10.1111/mmi.12318 [doi]

Tsai, P. P., Nagelschmidt, N., Kirchner, J., Stelzer, H. D., & Hackbarth, H. (2012)., Validation of an automatic system (DoubleCage) for detecting the location of animals during preference tests., Laboratory Animals, 46(1), 81-84. doi:10.1258/la.2011.011072 [doi]

Yu, I. T., Park, J. Y., Kim, S. H., Lee, J. S., Kim, Y. S., & Son, H. (2009), Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation, Neuropharmacology, 56(2), 473-480. doi:10.1016/j.neuropharm.2008.09.019 [doi]

Adlung L, Stapor P, et al., Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells., Cell Rep. 2021 Aug 10;36(6):109507. doi: 10.1016/j.celrep.2021.109507.

Altshuler A, Amitai-Lange A, Tarazi N, Dey S, Strinkovsky L, Hadad-Porat S, Bhattacharya S, Nasser W, Imeri J, Ben-David G, Abboud-Jarrous G, Tiosano B, Berkowitz E, Karin N, Savir Y, Shalom-Feuerstein R., Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing., Cell Stem Cell. 2021 Jul 1;28(7):1248-1261.e8. doi: 10.1016/j.stem.2021.04.003. Epub 2021 May 12.

Pirman T, Lenardič A, Nemec Svete A, Horvat S., Supplementation with >Your< Iron Syrup Corrects Iron Status in a Mouse Model of Diet-Induced Iron Deficiency., Biology (Basel). 2021 Apr 22;10(5). pii: 357. doi: 10.3390/biology10050357.

Salazar-Anzures T, Pastén-Hidalgo K, Sicilia-Argumedo G, Riverón-Negrete L, Hernández-Vázquez AJ, Fernanadez-Mejia C., Dietary biotin supplementation increases proliferation pathways in mice testes without affecting serum follicle-stimulating hormone levels and stem cell factor expression., Toxicol Appl Pharmacol. 2021 Dec 15;433:115774. doi: 10.1016/j.taap.2021.115774. Epub 2021 Oct 23.

Kasatkina LA, Ma C, Matlashov ME, Vu T, Li M, Kaberniuk AA, Yao J, Verkhusha VV., Optogenetic manipulation and photoacoustic imaging using a near-infrared transgenic mouse model, Nat Commun. 2022 May 19;13(1):2813. doi: 10.1038/s41467-022-30547-6.

Gaines CH, Schoenrock SA, Farrington J, Lee DF, Aponte-Collazo LJ, Shaw GD, Miller DR, Ferris MT, Pardo-Manuel de Villena F, Tarantino LM., Cocaine-Induced Locomotor Activation Differs Across Inbred Mouse Substrains, Front Psychiatry. 2022 May 6;13:800245. doi: 10.3389/fpsyt.2022.800245. eCollection 2022.

Goins AE, Gomez K, Ran D, Afaghpour-Becklund M, Khanna R, Alles SRA., Neuronal allodynic mechanisms of Slc7a5 (LAT1) in the spared nerve injury rodent model of neuropathic pain, Pflugers Arch. 2022 Apr;474(4):397-403. doi: 10.1007/s00424-021-02653-9. Epub 2022 Jan 20.

Rane SS, Dearman RJ, Kimber I, Derrick JP., Adaptation of an ELISA assay for detection of IgG2a responses against therapeutic monoclonal antibodies in a mouse immunization model, J Immunotoxicol. 2022 Dec;19(1):1-7. doi: 10.1080/1547691X.2021.2020937

Yoles-Frenkel M, Shea SD, Davison IG, Ben-Shaul Y., The Bruce effect: Representational stability and memory formation in the accessory olfactory bulb of the female mouse, Cell Rep. 2022 Aug 23;40(8):111262. doi: 10.1016/j.celrep.2022.111262.

Parhi L, Abed J, Shhadeh A, Alon-Maimon T, Udi S, Ben-Arye SL, Tam J, Parnas O, Padler-Karavani V, Goldman-Wohl D, Yagel S, Mandelboim O, Bachrach G., Placental colonization by Fusobacterium nucleatum is mediated by binding of the Fap2 lectin to placentally displayed Gal-GalNAc, Cell Rep. 2022 Mar 22;38(12):110537. doi: 10.1016/j.celrep.2022.110537.

Jonckheere AC, Seys SF, Steelant B, Decaesteker T, Dekoster K, Cremer J, Dilissen E, Schols D, Iwakura Y, Vande Velde G, Breynaert C, Schrijvers R, Vanoirbeek J, Ceuppens JL, Dupont LJ, Bullens DMA., Innate Lymphoid Cells Are Required to Induce Airway Hyperreactivity in a Murine Neutrophilic Asthma Model, Front Immunol. 2022 Mar 15;13:849155. doi: 10.3389/fimmu.2022.849155. eCollection 2022.

Infectious disease

Peniche AG, Osorio EY, Melby PC, Travi BL., Efficacy of histamine H1 receptor antagonists azelastine and fexofenadine against cutaneous Leishmania majorÂ infection, PLoS Negl Trop Dis. 2020 Aug 10;14(8):e0008482. doi: 10.1371/journal.pntd.0008482. eCollection 2020 Aug.

Duško Lainšček, Tina Fink, Vida Forstnerič, Iva Hafner-Bratkovič, Sara Orehek, Žiga Strmšek, Mateja Manček-Keber, Peter Pečan, Hana Esih, Špela Malenšek, Jana Aupič, Petra Dekleva, Tjaša Plaper, Sara Vidmar, Lucija Kadunc, Mojca Benčina, Neža Omersa, Gregor Anderluh, Florence Pojer, Kelvin Lau, David Hacker, Bruno Correia, David Peterhoff, Ralf Wagner, Roman Jerala, Immune response to vaccine candidates based on different types of nanoscaffolded RBD domain of the SARS-CoV-2 spike protein, bioRxiv 2020.08.28.244269; doi: https://doi.org/10.1101/2020.08.28.244269

Capone S, Raggioli A, Gentile M, et al., Immunogenicity of a new gorilla adenovirus vaccine candidate for COVID-19, bioRxiv 2020.10.22.349951; doi: https://doi.org/10.1101/2020.10.22.349951

Peterson NC, Berlin AA., Risk Assessment for Use of a Porcine Circovirus-Contaminated Reagent in a Barrier Maintained Rodent Colony, J Am Assoc Lab Anim Sci. 2020 Sep 1;59(5):575-579. doi: 10.30802/AALAS-JAALAS-20-000012. Epub 2020 Jun 30.

Solana JC, Ramírez L, Cook EC, Hernández-García E, Sacristán S, Martín ME, Manuel González V, Reguera RM, Balaña-Fouce R, Fresno M, Requena JM, Iborra S, Soto M., Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice, Vaccines (Basel). 2020 Mar 23;8(1):141. doi: 10.3390/vaccines8010141.

Flommersfeld S, et al., Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection., Immunity. 2021 Oct 12;54(10):2288-2304.e7. doi: 10.1016/j.immuni.2021.08.002. Epub 2021 Aug 25.

Collins KA, Brod F, Snaith R, Ulaszewska M, Longley RJ, Salman AM, Gilbert SC, Spencer AJ, Franco D, Ballou WR, Hill AVS., Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice., Sci Rep. 2021 May 24;11(1):10792. doi: 10.1038/s41598-021-90290-8.

Spencer AJ, McKay PF, Belij-Rammerstorfer S, Ulaszewska M, Bissett CD, Hu K, Samnuan K, Blakney AK, Wright D, Sharpe HR, Gilbride C, Truby A, Allen ER, Gilbert SC, Shattock RJ, Lambe T., Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice., Nat Commun. 2021 May 17;12(1):2893. doi: 10.1038/s41467-021-23173-1.

Soto M, Ramirez L, Solana JC, et al., Inoculation of the Leishmania infantum HSP70-II Null Mutant Induces Long-Term Protection against L. amazonensis Infection in BALB/c Mice., Microorganisms. 2021 Feb 12;9(2). pii: 363. doi: 10.3390/microorganisms9020363.

Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinson GB, Park YJ, Moin SM, Acton OJ, Ravichandran R, Murphy M, Pettie D, Matheson N, Carter L, Creanga A, Watson MJ, Kephart S, Ataca S, Vaile JR, Ueda G, Crank MC, Stewart L, Lee KK, Guttman M, et al., Quadrivalent influenza nanoparticle vaccines induce broad protection., Nature. 2021 Apr;592(7855):623-628. doi: 10.1038/s41586-021-03365-x. Epub 2021 Mar 24.

Moin SM, Boyington JC, Boyoglu-Barnum S, Gillespie RA, Cerutti G, Cheung CS, Cagigi A, Gallagher JR, Brand J, Prabhakaran M, Tsybovsky Y, Stephens T, Fisher BE, Creanga A, Ataca S, Rawi R, Corbett KS, Crank MC, Karlsson Hedestam GB, Gorman J, McDermott AB, Harris AK, Zhou T, Kwong PD, Shapiro L, Mascola JR, Graham BS, Kanekiyo M., Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses, Immunity. 2022 Dec 13;55(12):2405-2418.e7. doi: 10.1016/j.immuni.2022.10.015. Epub 2022 Nov 9.

Chaudhuri M, Singha UK, Vanderloop BH, Tripathi A, Nes WD., Steroidal Antimetabolites Protect Mice against Trypanosoma brucei, Molecules. 2022 Jun 25;27(13):4088. doi: 10.3390/molecules27134088

Cox G, Gonzalez AJ, Ijezie EC, Rodriguez A, Miller CR, Van Leuven JT, Miura TA., Priming With Rhinovirus Protects Mice Against a Lethal Pulmonary Coronavirus Infection, Front Immunol. 2022 May 30;13:886611. doi: 10.3389/fimmu.2022.886611

Chen, C., Saubi, N., Kilpeläinen, A., Joseph-Munné, J., Chimeric Human Papillomavirus-16 Virus-like Particles Presenting P18I10 and T20 Peptides from HIV-1 Envelope Induce HPV16 and HIV-1-Specific Humoral and T Cell-Mediated Immunity in BALB/c Mice, Vaccines 2023, 11(1), 15; https://doi.org/10.3390/vaccines11010015

Iwadate Y, Golubeva YA, Slauch JM., Cation Homeostasis: Coordinate Regulation of Polyamine and Magnesium Levels in Salmonella, mBio. 2022 Dec 7:e0269822. doi: 10.1128/mbio.02698-22. Online ahead of print.

Karampetsou K, Koutsoni OS, Badounas F, Angelis A, Gogou G, Skaltsounis LA, Halabalaki M, Dotsika E., Exploring the Immunotherapeutic Potential of Oleocanthal against Murine Cutaneous Leishmaniasis, Planta Med. 2022 Aug;88(9-10):783-793. doi: 10.1055/a-1843-9788. Epub 2022 Jul 8.

Monoclonal antibodies

Coutant, F., Sanchez David, R. Y., Felix, T., Boulay, A., Caleechurn, L., Souque, P., . . . Charneau, P. (2012)., A nonintegrative lentiviral vector-based vaccine provides long-term sterile protection against malaria., PloS One, 7(11), e48644. doi:10.1371/journal.pone.0048644 [doi]

Reggiani, F., Labanca, V., Mancuso, P., Rabascio, C., Talarico, G., Orecchioni, S., . . . Bertolini, F. (2017)., Adipose progenitor cell secretion of GM-CSF and MMP9 promotes a stromal and immunological microenvironment that supports breast cancer progression, Cancer Research, 77(18), 5169-5182. doi:10.1158/0008-5472.CAN-17-0914 [doi]

Borges, O., Silva, M., de Sousa, A., Borchard, G., Junginger, H. E., & Cordeiro-da-Silva, A. (2008)., Alginate coated chitosan nanoparticles are an effective subcutaneous adjuvant for hepatitis B surface antigen., International Immunopharmacology, 8(13-14), 1773-1780. doi:10.1016/j.intimp.2008.08.013 [doi]

Aranda, J., Garrido, M. E., Cortes, P., Llagostera, M., & Barbe, J. (2008)., Analysis of the protective capacity of three streptococcus suis proteins induced under divalent-cation-limited conditions., Infection and Immunity, 76(4), 1590-1598. doi:10.1128/IAI.00987-07 [doi]

Roberts, A., Lamirande, E. W., Vogel, L., Jackson, J. P., Paddock, C. D., Guarner, J., . . . Subbarao, K. (2008)., Animal models and vaccines for SARS-CoV infection., Virus Research, 133(1), 20-32. doi:S0168-1702(07)00113-X [pii]

Dobbs, N. A., Zhou, X., Pulse, M., Hodge, L. M., Schoeb, T. R., & Simecka, J. W. (2014), Antigen-pulsed bone marrow-derived and pulmonary dendritic cells promote Th2 cell responses and immunopathology in lungs during the pathogenesis of murine mycoplasma pneumonia., Journal of Immunology (Baltimore, Md.: 1950), 193(3), 1353-1363. doi:10.4049/jimmunol.1301772 [doi]

Di Niro, R., Ziller, F., Florian, F., Crovella, S., Stebel, M., Bestagno, M., . . . Sblattero, D. (2007), Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models, BMC Biotechnology, 7, 46. doi:1472-6750-7-46 [pii]

Aranda, J., Cortes, P., Garrido, M. E., Fittipaldi, N., Llagostera, M., Gottschalk, M., & Barbe, J. (2009)., Contribution of the FeoB transporter to streptococcus suis virulence. International Microbiology, The Official Journal of the Spanish Society for Microbiology, 12(2), 137-143. doi:im2306131 [pii]

Kapur, R., Heitink-Polle, K. M., Porcelijn, L., Bentlage, A. E., Bruin, M. C., Visser, R., . . . Vidarsson, G. (2015)., C-reactive protein enhances IgG-mediated phagocyte responses and thrombocytopenia., Blood, 125(11), 1793-1802. doi:10.1182/blood-2014-05-579110 [doi]

Hastey, C. J., Elsner, R. A., Barthold, S. W., & Baumgarth, N. (2012)., Delays and diversions mark the development of B cell responses to borrelia burgdorferi infection., Journal of Immunology (Baltimore, Md.: 1950), 188(11), 5612-5622. doi:10.4049/jimmunol.1103735 [doi]

Pence, B. D., Hester, S. N., Donovan, S. M., & Woods, J. A. (2012), Dietary whole glucan particles do not affect antibody or cell-mediated immune responses to influenza virus vaccination in mice., Immunological Investigations, 41(3), 275-289. doi:10.3109/08820139.2011.628732 [doi]

Erova, T. E., Rosenzweig, J. A., Sha, J., Suarez, G., Sierra, J. C., Kirtley, M. L., . . . Chopra, A. K. (2013)., Evaluation of protective potential of yersinia pestis outer membrane protein antigens as possible candidates for a new-generation recombinant plague vaccine., Clinical and Vaccine Immunology : CVI, 20(2), 227-238. doi:10.1128/CVI.00597-12 [doi]

Veceric-Haler, Z., Erman, A., Cerar, A., Motaln, H., Kolosa, K., Lah Turnsek, T., . . . Perse, M. (2016)., Improved protective effect of umbilical cord stem cell transplantation on cisplatin-induced kidney injury in mice pretreated with antithymocyte globulin, Stem Cells International, 2016, 3585362. doi:10.1155/2016/3585362 [doi]

Cabrera, M., Pewe, L. L., Harty, J. T., & Frevert, U. (2013), In vivo CD8+ T cell dynamics in the liver of plasmodium yoelii immunized and infected mice, PloS One, 8(8), e70842. doi:10.1371/journal.pone.0070842 [doi]

Aranda, J., Teixido, L., Fittipaldi, N., Cortes, P., Llagostera, M., Gottschalk, M., & Barbe, J. (2012)., Inactivation of the gene encoding zinc-binding lipoprotein 103 impairs the infectivity of streptococcus suis., Canadian Journal of Veterinary Research = Revue Canadienne De Recherche Veterinaire, 76(1), 72-76.

De Witte, C., Taminiau, B., Flahou, B., Hautekiet, V., Daube, G., Ducatelle, R., & Haesebrouck, F. (2018), In-feed bambermycin medication induces anti-inflammatory effects and prevents parietal cell loss without influencing helicobacter suis colonization in the stomach of mice., Veterinary Research, 49(1), 35-018-0530-1. doi:10.1186/s13567-018-0530-1 [doi]

Terwisscha van Scheltinga, A. G., van Dam, G. M., Nagengast, W. B., Ntziachristos, V., Hollema, H., Herek, J. L., . . . de Vries, E. G. (2011)., Intraoperative near-infrared fluorescence tumor imaging with vascular endothelial growth factor and human epidermal growth factor receptor 2 targeting antibodies., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 52(11), 1778-1785. doi:10.2967/jnumed.111.092833 [doi]

Mastelic Gavillet, B., Eberhardt, C. S., Auderset, F., Castellino, F., Seubert, A., Tregoning, J. S., . . . Siegrist, C. A. (2015), MF59 mediates its B cell adjuvanticity by promoting T follicular helper cells and thus germinal center responses in adult and early life., Journal of Immunology (Baltimore, Md.: 1950), 194(10), 4836-4845. doi:10.4049/jimmunol.1402071 [doi]

Kemper, K., Prasetyanti, P. R., De Lau, W., Rodermond, H., Clevers, H., & Medema, J. P. (2012)., Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells, Stem Cells (Dayton, Ohio), 30(11), 2378-2386. doi:10.1002/stem.1233 [doi]

Bubeck Wardenburg, J., Palazzolo-Ballance, A. M., Otto, M., Schneewind, O., & DeLeo, F. R. (2008)., Panton-valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant staphylococcus aureus disease., The Journal of Infectious Diseases, 198(8), 1166-1170. doi:10.1086/592053 [doi]

Cray, C., Besselsen, D. G., Hart, J. L., Yoon, D., Rodriguez, M., Zaias, J., & Altman, N. H. (2010)., Quantitation of acute phase proteins and protein electrophoresis in monitoring the acute inflammatory process in experimentally and naturally infected mice, Comparative Medicine, 60(4), 263-271.

Odeh, A. N., & Simecka, J. W. (2016)., Regulatory CD4+CD25+ T cells dampen inflammatory disease in murine mycoplasma pneumonia and promote IL-17 and IFN-gamma responses., PloS One, 11(5), e0155648. doi:10.1371/journal.pone.0155648 [doi]

Jahagirdar, R., Attwell, S., Marusic, S., Bendele, A., Shenoy, N., McLure, K. G., . . . Kulikowski, E. (2017)., RVX-297, a BET bromodomain inhibitor, has therapeutic effects in preclinical models of acute inflammation and autoimmune disease., Molecular Pharmacology, 92(6), 694-706. doi:10.1124/mol.117.110379 [doi]

Elhaik Goldman, S., Dotan, S., Talias, A., Lilo, A., Azriel, S., Malka, I., . . . Mizrachi Nebenzahl, Y. (2016)., Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice., International Journal of Molecular Medicine, 37(4), 1127-1138. doi:10.3892/ijmm.2016.2512 [doi]

Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., & Baric, R. (2008), Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge, Journal of Virology, 82(7), 3220-3235. doi:10.1128/JVI.02377-07 [doi]

Hernandez, J. L., Padilla, L., Dakhel, S., Coll, T., Hervas, R., Adan, J., . . . Messeguer, R. (2013)., Therapeutic targeting of tumor growth and angiogenesis with a novel anti-S100A4 monoclonal antibody., PloS One, 8(9), e72480. doi:10.1371/journal.pone.0072480 [doi]

Kuck, L. R., Byrne-Nash, R., Gillis, J., Bueter, K., Couzens, L. K., Eichelberger, M. C., & Rowlen, K. L. (2018)., VaxArray for hemagglutinin and neuraminidase potency testing of influenza vaccines., Vaccine, 36(21), 2937-2945. doi:S0264-410X(18)30545-0 [pii]

Oncology

Karp NA, Wilson Z, Stalker E, Mooney L, Lazic SE, Zhang B, Hardaker E., A multi-batch design to deliver robust estimates of efficacy and reduce animal use - a syngeneic tumour case study, Sci Rep. 2020 Apr 10;10(1):6178. doi: 10.1038/s41598-020-62509-7.

Forte, B. L., Slosky, L. M., Zhang, H., Arnold, M. R., Staatz, W. D., Hay, M., . . . Vanderah, T. W. (2016)., Angiotensin-(1-7)/Mas receptor as an antinociceptive agent in cancer-induced bone pain., Pain, 157(12), 2709-2721. doi:10.1097/j.pain.0000000000000690 [doi]

Bonavita E, Bromley CP, Jonsson G, Pelly VS, Sahoo S, Walwyn-Brown K, Mensurado S, Moeini A, Flanagan E, Bell CR, Chiang SC, Chikkanna-Gowda CP, Rogers N, Silva-Santos B, Jaillon S, Mantovani A, Reis E Sousa C, Guerra N, Davis DM, Zelenay S., Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade, Immunity. 2020 Dec 15;53(6):1215-1229.e8. doi: 10.1016/j.immuni.2020.10.020. Epub 2020 Nov 20.

NuĂąez-Rivera A, Fournier PGJ, Arellano DL, Rodriguez-Hernandez AG, Vazquez-Duhalt R, Cadena-Nava RD., Brome mosaic virus-like particles as siRNA nanocarriers for biomedical purposes, Beilstein J Nanotechnol. 2020 Feb 20;11:372-382. doi: 10.3762/bjnano.11.28. eCollection 2020.

Arroyo-Crespo, Juan J; Armiñán, Ana; Charbonnier, David; Deladriere, Coralie; Palomino-Schätzlein, Martina; Lamas-Domingo, Rubén; Forteza, Jerónimo; Pineda-Lucena, Antonio; Vicent, María, Characterization of triple-negative breast cancer preclinical models provides functional evidence of metastatic progression., International journal of cancer Vol.145, 2019

Teijeira Á, Garasa S, Gato M, Alfaro C, Migueliz I, Cirella A, de Andrea C, Ochoa MC, Otano I, Etxeberria I, Andueza MP, Nieto CP, Resano L, Azpilikueta A, Allegretti M, de Pizzol M, Ponz-Sarvisé M, Rouzaut A, Sanmamed MF, Schalper K, Carleton M, Mellado M, Rodriguez-Ruiz ME, Berraondo P, Perez-Gracia JL, Melero I., CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity, Immunity. 2020 May 19;52(5):856-871.e8. doi: 10.1016/j.immuni.2020.03.001. Epub 2020 Apr 13.

Falvo P, Orecchioni S, Hillje R, Raveane A, Mancuso P, Camisaschi C, Luzi L, Pelicci P, Bertolini F., Cyclophosphamide and vinorelbine activate stem-like CD8+ T cells and improve anti-PD-1 efficacy in triple-negative breast cancer, Cancer Res. 2020 Dec 2:canres.1818.2020. doi: 10.1158/0008-5472.CAN-20-1818. Online ahead of print.

Shamni, Ofer; Grievink, Hilbert; Itamar, Batel; Mishani, Eyal; Abourbeh, Galith;, Development of a Fluorinated Analogue of Erlotinib for PET Imaging of EGFR Mutation-Positive NSCLC, Molecular imaging and biology Vol.21, 2019

Suurs FV, Qiu SQ, Yim JJ, Schröder CP, Timmer-Bosscha H, Bensen ES, Santini JT Jr, de Vries EGE, Bogyo M, van Dam GM., Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model, EJNMMI Res. 2020 Sep 29;10(1):111. doi: 10.1186/s13550-020-00688-0.

Rivera-Huerta, M., Lizarraga-Grimes, V. L., Castro-Torres, I. G., Tinoco-Mendez, M., Macias-Rosales, L., Sanchez-Bartez, F., . . . Gracia-Mora, M. I. (2017)., Functional effects of prebiotic fructans in colon cancer and calcium metabolism in animal models., BioMed Research International, 2017, 9758982. doi:10.1155/2017/9758982 [doi]

Sanchez-Gonzalez, B., Garcia-Vazquez, F. J., Farfan-Morales, J. E., & Jimenez-Zamudio, L. A. (2015)., Increased NHC cells in the peritoneal cavity of plasmacytoma susceptible BALB/c mouse., Mediators of Inflammation, 2015, 313140. doi:10.1155/2015/313140 [doi]

Kranjc Brezar S, Mrak V, Bosnjak M, Savarin M, Sersa G, Cemazar M., Intratumoral Gene Electrotransfer of Plasmid DNA Encoding shRNA against Melanoma Cell Adhesion Molecule Radiosensitizes Tumors by Antivascular Effects and Activation of an Immune Response, Vaccines (Basel). 2020 Mar 19;8(1):135. doi: 10.3390/vaccines8010135.

Alessandri, Giulio; Coccè, Valentina; Pastorino, Fabio; Paroni, Rita; Dei Cas, Michele; Restelli, Francesco; Pollo, Bianca; Gatti, Laura; Tremolada, Carlo; Berenzi, Angiola; Parati, Eugenio; Brini, Anna Teresa; Bondiolotti, Gianpietro; Ponzoni, Mirco; Pessina, Augusto, Microfragmented human fat tissue is a natural scaffold for drug delivery: Potential application in cancer chemotherapy., Journal of controlled release : official journal of the Controlled Release Society Vol.302, 2019

Bach-Griera M, Campo-Pérez V, Barbosa S, Traserra S, Guallar-Garrido S, Moya-Andérico L, Herrero-Abadía P, Luquin M, Rabanal RM, Torrents E, Julián E., Mycolicibacterium brumae Is a Safe and Non-Toxic Immunomodulatory Agent for Cancer Treatment, Vaccines (Basel). 2020 Apr 25;8(2):198. doi: 10.3390/vaccines8020198.

Raineri D, Dianzani C, Cappellano G, Maione F, Baldanzi G, Iacobucci I, Clemente N, Baldone G, Boggio E, Gigliotti CL, Boldorini R, Rojo JM, Monti M, Birolo L, Dianzani U, Chiocchetti A., Osteopontin binds ICOSL promoting tumor metastasis, Commun Biol. 2020 Oct 26;3(1):615. doi: 10.1038/s42003-020-01333-1.

Di Tano M, Raucci F, Vernieri C, Caffa I, Buono R, Fanti M, Brandhorst S, Curigliano G, Nencioni A, de Braud F, Longo VD., Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers, Nat Commun. 2020 May 11;11(1):2332. doi: 10.1038/s41467-020-16243-3.

Pfitzer, Lisa; Moser, Christina; Gegenfurtner, Florian; Arner, Anja; Foerster, Florian; Atzberger, Carina; Zisis, Themistoklis; Kubisch-Dohmen, Rebekka; Busse, Johanna; Smith, Rebecca, Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy., Cell death & disease Vol.10, 2019

Drescher F, Juárez P, Arellano DL, Serafín-Higuera N, Olvera-Rodriguez F, Jiménez S, Licea-Navarro AF, Fournier PG., TIE2 Induces Breast Cancer Cell Dormancy and Inhibits the Development of Osteolytic Bone Metastases, Cancers (Basel). 2020 Apr 3;12(4):868. doi: 10.3390/cancers12040868.

Nguyen, O. N., Grimm, C., Schneider, L. S., Chao, Y. K., Atzberger, C., Bartel, K., . . . Vollmar, A. M. (2017), Two-pore channel function is crucial for the migration of invasive cancer cells., Cancer Research, 77(6), 1427-1438. doi:10.1158/0008-5472.CAN-16-0852 [doi]

Allen KL, Cann J, Zhao W, Peterson N, Lazzaro M, Zhong H, Wu H, Dall'Acqua WF, Borrok MJ, Damschroder MM, Tsui P, Li Q., Upregulation of annexin A1 protein expression in the intratumoral vasculature of human non-small-cell lung carcinoma and rodent tumor models, PLoS One. 2020 Jun 4;15(6):e0234268. doi: 10.1371/journal.pone.0234268. eCollection 2020.

Larrouqučre L, Berthier S, Chovelon B, Garrel C, Vacchina V, Paucot H, Boutonnat J, Faure P, Hazane-Puch F., Preclinical Evaluation of Sodium Selenite in Mice: Toxicological and Tumor Regression Studies after Striatum Implantation of Human Glioblastoma Stem Cells., Int J Mol Sci. 2021 Sep 30;22(19). pii: 10646. doi: 10.3390/ijms221910646.

Marcheteau E, Farge T, et al., Thrombospondin-1 Silencing Improves Lymphocyte Infiltration in Tumors and Response to Anti-PD-1 in Triple-Negative Breast Cancer., Cancers (Basel). 2021 Aug 12;13(16). pii: 4059. doi: 10.3390/cancers13164059.

Baram T, Erlichman N, Dadiani M, Balint-Lahat N, Pavlovski A, Meshel T, Morzaev-Sulzbach D, Gal-Yam EN, Barshack I, Ben-Baruch A., Chemotherapy Shifts the Balance in Favor of CD8+ TNFR2+ TILs in Triple-Negative Breast Tumors., Cells. 2021 Jun 8;10(6). pii: 1429. doi: 10.3390/cells10061429.

Suurs FV, Lorenczewski G, Bailis JM, Stienen S, Friedrich M, Lee F, van der Vegt B, de Vries EGE, de Groot DA, Lub-de Hooge MN., Mesothelin/CD3 half-life extended bispecific T-cell engager molecule shows specific tumor uptake and distributes to mesothelin and CD3 expressing tissues., J Nucl Med. 2021 Apr 30. pii: jnumed.120.259036. doi: 10.2967/jnumed.120.259036. [Epub ahead of print]

Petruk N, Tuominen S, Åkerfelt M, Mattsson J, Sandholm J, Nees M, Yegutkin GG, Jukkola A, Tuomela J, Selander KS., CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer., Sci Rep. 2021 Mar 16;11(1):6035. doi: 10.1038/s41598-021-85379-z.

Ursic K, Kos S, Kamensek U, Cemazar M, Miceska S, Markelc B, Bucek S, Staresinic B, Kloboves Prevodnik V, Heller R, Sersa G., Potentiation of electrochemotherapy effectiveness by immunostimulation with IL-12 gene electrotransfer in mice is dependent on tumor immune status., J Control Release. 2021 Apr 10;332:623-635. doi: 10.1016/j.jconrel.2021.03.009. Epub 2021 Mar 8.

Falvo P, Orecchioni S, Hillje R, Raveane A, Mancuso P, Camisaschi C, Luzi L, Pelicci P, Bertolini F., Cyclophosphamide and Vinorelbine Activate Stem-Like CD8(+) T Cells and Improve Anti-PD-1 Efficacy in Triple-Negative Breast Cancer., Cancer Res. 2021 Feb 1;81(3):685-697. doi: 10.1158/0008-5472.CAN-20-1818. Epub 2020 Dec 2. Erratum in: Cancer Res. 2021 Jun 15;81(12):3426.

Nie P, Kalidindi T, Nagle VL, Wu X, Li T, Liao GP, Frost G, Henry KE, Punzalan B, Carter LM, Lewis JS, Pillarsetty NVK, Li YM., Imaging of Cancer Îł-Secretase Activity Using an Inhibitor-Based PET Probe., Clin Cancer Res. 2021 Nov 15;27(22):6145-6155. doi: 10.1158/1078-0432.CCR-21-0940. Epub 2021 Sep 2.

Maulhardt H, Marin A, Hesseltine H, diZerega G., Submicron particle docetaxel intratumoral injection in combination with anti-mCTLA-4 into 4T1-Luc orthotopic implants reduces primary tumor and metastatic pulmonary lesions., Med Oncol. 2021 Jul 31;38(9):106. doi: 10.1007/s12032-021-01555-1.

Wedekind MF, Miller KE, Chen CY, Wang PY, Hutzen BJ, Currier MA, Nartker B, Roberts RD, Boon L, Conner J, LaHaye S, Kelly BJ, Gordon D, White P, Mardis ER, Cripe TP., Endogenous retrovirus envelope as a tumor-associated immunotherapeutic target in murine osteosarcoma., iScience. 2021 Jun 19;24(7):102759. doi: 10.1016/j.isci.2021.102759. eCollection 2021 Jul 23.

Jang SC, Economides KD, Moniz RJ, Sia CL, Lewis N, McCoy C, Zi T, Zhang K, Harrison RA, Lim J, Dey J, Grenley M, Kirwin K, Ross NL, Bourdeau R, Villiger-Oberbek A, Estes S, Xu K, Sanchez-Salazar J, Dooley K, Dahlberg WK, Williams DE, et al., ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance., Commun Biol. 2021 Apr 22;4(1):497. doi: 10.1038/s42003-021-02004-5.

Lusche DF, Wessels DJ, Reis RJ, Forrest CC, Thumann AR, Soll DR., New monoclonal antibodies that recognize an unglycosylated, conserved, extracellular region of CD44 in vitro and in vivo, and can block tumorigenesis., PLoS One. 2021 Apr 23;16(4):e0250175. doi: 10.1371/journal.pone.0250175. eCollection 2021.

Huang CH, Dong T, Phung AT, Shah JR, Larson C, Sanchez AB, Blair SL, Oronsky B, Trogler WC, Reid T, Kummel AC., Full Remission of CAR-Deficient Tumors by DOTAP-Folate Liposome Encapsulation of Adenovirus, ACS Biomater Sci Eng. 2022 Dec 12;8(12):5199-5209. doi: 10.1021/acsbiomaterials.2c00966. Epub 2022 Nov 17.

Alsaid H, Cheng SH, Bi M, Xie F, Rambo M, Skedzielewski T, Hoang B, Mohanan S, Comroe D, Gehman A, Hsu CY, Farhangi K, Tran H, Sherina V, Doan M, Groseclose MR, Hopson CB, Brett S, Wilson IA, Nicholls A, Ballas M, Waight JD, Jucker BM., Immuno-PET Monitoring of CD8(+) T Cell Infiltration Post ICOS Agonist Antibody Treatment Alone and in Combination with PD-1 Blocking Antibody Using a (89)Zr Anti-CD8(+) Mouse Minibody in EMT6 Syngeneic Tumor Mouse, Mol Imaging Biol. 2022 Oct 20. doi: 10.1007/s11307-022-01781-7. Online ahead of print.

Liu Y, Betori RC, Pagacz J, Frost GB, Efimova EV, Wu D, Wolfgeher DJ, Bryan TM, Cohen SB, Scheidt KA, Kron SJ., Targeting telomerase reverse transcriptase with the covalent inhibitor NU-1 confers immunogenic radiation sensitization, Cell Chem Biol. 2022 Oct 20;29(10):1517-1531.e7. doi: 10.1016/j.chembiol.2022.09.002. Epub 2022 Oct 6.

Karimaa M, Riikonen R, Kettunen H, Taavitsainen P, Ramela M, Chrusciel M, Karlsson S, Rummakko P, Simola O, Wohlfahrt G, Hakulinen P, Vuorela A, Joensuu H, Utriainen T, Fizazi K, Oksala R., First-in-Class Small Molecule to Inhibit CYP11A1 and Steroid Hormone Biosynthesis, Mol Cancer Ther. 2022 Dec 2;21(12):1765-1776. doi: 10.1158/1535-7163.MCT-22-0115.

Meraviglia-Crivelli D, Villanueva H, Menon AP, Zheleva A, Moreno B, Villalba-Esparza M, Pastor F., A pan-tumor-siRNA aptamer chimera to block nonsense-mediated mRNA decay inflames and suppresses tumor progression, Mol Ther Nucleic Acids. 2022 Jul 20;29:413-425. doi: 10.1016/j.omtn.2022.07.017.

Gu Z, Da Silva CG, Hao Y, Schomann T, Camps MGM, van der Maaden K, Liu Q, Ossendorp F, Cruz LJ., Effective combination of liposome-targeted chemotherapy and PD-L1 blockade of murine colon cancer, J Control Release. 2022 Dec 9;353:490-506. doi: 10.1016/j.jconrel.2022.11.049.

Waissengrin B, Leshem Y, Taya M, Meiri D, Merimsky O, Shamai S, Wolf I, Rubinek T., The use of medical cannabis concomitantly with immune checkpoint inhibitors in non-small cell lung cancer: A sigh of relief?, Eur J Cancer. 2023 Feb;180:52-61. doi: 10.1016/j.ejca.2022.11.022.

Kol A, Fan X, Wazynska MA, van Duijnhoven SMJ, Giesen D, Plat A, Van Eenennaam H, Elsinga PH, Nijman HW, de Bruyn M., Development of (89)Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration, J Immunother Cancer. 2022 Dec;10(12):e004877. doi: 10.1136/jitc-2022-004877.

Bordat A, Boissenot T, Ibrahim N, Ferrere M, Levêque M, Potiron L, Denis S, Garcia-Argote S, Carvalho O, Abadie J, Cailleau C, Pieters G, Tsapis N, Nicolas J., A Polymer Prodrug Strategy to Switch from Intravenous to Subcutaneous Cancer Therapy for Irritant/Vesicant Drugs, J Am Chem Soc. 2022 Oct 19;144(41):18844-18860. doi: 10.1021/jacs.2c04944. Epub 2022 Oct 4.

Diamond JR, Pitts TM, Ungermannova D, Nasveschuk CG, Zhang G, Phillips AJ, Bagby SM, Pafford J, Yacob BW, Newton TP, Tentler JJ, Gittleman B, Hartman SJ, DeMattei JA, Winkler JD, Wendt MK, Schiemann WP, Eckhardt SG, Liu X, Piscopio AD., Preclinical Development of the Class-I–Selective Histone Deacetylase Inhibitor OKI-179 for the Treatment of Solid Tumors, Mol Cancer Ther. 2022 Mar 1;21(3):397-406. doi: 10.1158/1535-7163.MCT-21-0455

Hezkiy EE, Kumar S, Gahramanov V, Yaglom J, Hesin A, Jadhav SS, Guzev E, Patel S, Avinery E, Firer MA, Sherman MY., Search for Synergistic Drug Combinations to Treat Chronic Lymphocytic Leukemia, Cells. 2022 Nov 18;11(22):3671. doi: 10.3390/cells11223671

Gutwillig A, Santana-Magal N, Farhat-Younis L, Rasoulouniriana D, Madi A, Luxenburg C, Cohen J, Padmanabhan K, Shomron N, Shapira G, Gleiberman A, Parikh R, Levy C, Feinmesser M, Hershkovitz D, Zemser-Werner V, Zlotnik O, Kroon S, Hardt WD, Debets R, Reticker-Flynn NE, Rider P, Carmi Y., Transient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy, Elife. 2022 Sep 20;11:e80315. doi: 10.7554/eLife.80315.

Hangiu O, Compte M, Dinesen A, Navarro R, Tapia-Galisteo A, Mandrup OA, Erce-Llamazares A, Lázaro-Gorines R, Nehme-Álvarez D, Domínguez-Alonso C, Harwood SL, Alfonso C, Blanco B, Rubio-Pérez L, Jiménez-Reinoso A, Díez-Alonso L, Blanco FJ, Sanz L, Howard KA, Álvarez-Vallina L., Tumor targeted 4-1BB agonist antibody-albumin fusions with high affinity to FcRn induce anti-tumor immunity without toxicity, iScience. 2022 Aug 17;25(9):104958. doi: 10.1016/j.isci.2022.104958. eCollection 2022 Sep 16.

Kumar N, Papillon-Cavanagh S, Tang H, Wang S, Stromko C, Ho CP, Soni-Sheth S, Vasquez-Grinnell S, Broz ML, Tenney DJ, Wichroski MJ, Walsh AM, Hu Y, Benci JL., A multi‐omic single cell sequencing approach to develop a CD8 T cell specific gene signature for anti‐PD1 response in solid tumors, Int J Cancer. 2022 Dec 1;151(11):2043-2054. doi: 10.1002/ijc.34218.

Kandasamy M, Gileadi U, Rijal P, Tan TK, Lee LN, Chen J, Prota G, Klenerman P, Townsend A, Cerundolo V., Recombinant single-cycle influenza virus with exchangeable pseudotypes allows repeated immunization to augment anti-tumour immunity with immune checkpoint inhibitors, Elife. 2023 Jan 10;12:e76414. doi: 10.7554/eLife.76414.

van Beijnum JR, Huijbers EJM, van Loon K, Blanas A, Akbari P, Roos A, Wong TJ, Denisov SS, Hackeng TM, Jimenez CR, Nowak-Sliwinska P, Griffioen AW., Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy, Nat Commun. 2022 May 23;13(1):2842. doi: 10.1038/s41467-022-30063-7.

Hampton JD, Peterson EJ, Katner SJ, Turner TH, Alzubi MA, Harrell JC, Dozmorov MG, Turner JBM, Gigliotti PJ, Kraskauskiene V, Shende M, Idowu MO, Puchalapalli M, Hu B, Litovchick L, Katsuta E, Takabe K, Farrell NP, Koblinski JE., Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer, Mol Cancer Ther. 2022 Feb;21(2):271-281. doi: 10.1158/1535-7163.MCT-20-0969

Benguigui M, Vorontsova A, Timaner M, Levin S, Haj-Shomaly J, Deo A, Menachem R, Manobla B, Cooper TJ, Raviv Z, Shaked Y., Bv8 Blockade Sensitizes Anti-PD1 Therapy Resistant Tumors, Front Immunol. 2022 Jul 7;13:903591. doi: 10.3389/fimmu.2022.903591

Gomes AP, Ilter D, Low V, Drapela S, Schild T, Mullarky E, Han J, Elia I, Broekaert D, Rosenzweig A, Nagiec M, Nunes JB, Schaffer BE, Mutvei AP, Asara JM, Cantley LC, Fendt SM, Blenis J., Altered propionate metabolism contributes to tumour progression and aggressiveness, Nat Metab. 2022 Apr;4(4):435-443. doi: 10.1038/s42255-022-00553-5. Epub 2022 Mar 31.

Tcyganov EN, Sanseviero E, Marvel D, Beer T, Tang HY, Hembach P, Speicher DW, Zhang Q, Donthireddy LR, Mostafa A, Tsyganova S, Pisarev V, Laufer T, Ignatov D, Ferrone S, Meyer C, Maby-El Hajjami H, Speiser DE, Altiok S, Antonia S, Xu X, Xu W, Zheng C, Schuchter LM, Amaravadi RK, Mitchell TC, Karakousis GC, Yuan Z, Montaner LJ, Celis E, Gabrilovich DI., Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy, Cancer Cell. 2022 Oct 10;40(10):1173-1189.e6.

Feola S, Chiaro J, Martins B, Russo S, Fusciello M, Ylösmäki E, Bonini C, Ruggiero E, Hamdan F, Feodoroff M, Antignani G, Viitala T, Pesonen S, Grönholm M, Branca RMM, Lehtiö J, Cerullo V., A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines, Elife. 2022 Mar 22;11:e71156. doi: 10.7554/eLife.71156.

Pharmacology

Narra, H. P., Shubitz, L. F., Mandel, M. A., Trinh, H. T., Griffin, K., Buntzman, A. S., . . . Orbach, M. J. (2016), A coccidioides posadasii CPS1 deletion mutant is avirulent and protects mice from lethal infection., Infection and Immunity, 84(10), 3007-3016. doi:10.1128/IAI.00633-16 [doi]

Hirschberg, H., van Kuijk, S., Loch, J., Jiskoot, W., Bouwstra, J., Kersten, G., & Amorij, J. P. (2012)., A combined approach of vesicle formulations and microneedle arrays for transcutaneous immunization against hepatitis B virus., European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences, 46(1-2), 1-7. doi:10.1016/j.ejps.2012.01.013 [doi]

Bolles, M., Deming, D., Long, K., Agnihothram, S., Whitmore, A., Ferris, M., . . . Baric, R. S. (2011)., A double-inactivated severe acute respiratory syndrome coronavirus vaccine provides incomplete protection in mice and induces increased eosinophilic proinflammatory pulmonary response upon challenge., Journal of Virology, 85(23), 12201-12215. doi:10.1128/JVI.06048-11 [doi]

Cestari, I., Kalidas, S., Monnerat, S., Anupama, A., Phillips, M. A., & Stuart, K. (2013)., A multiple aminoacyl-tRNA synthetase complex that enhances tRNA-aminoacylation in african trypanosomes., Molecular and Cellular Biology, 33(24), 4872-4888. doi:10.1128/MCB.00711-13 [doi]

Sweeney, F. F., O'Leary, O. F., & Cryan, J. F. (2014)., Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice., Neuropharmacology, 81, 303-310. doi:10.1016/j.neuropharm.2013.08.039 [doi]

Ferrini E, Mecozzi L, Corsi L, Ragionieri L, Donofrio G, Stellari FF., Alfaxalone and Dexmedetomidine as an Alternative to Gas Anesthesia for Micro-CT Lung Imaging in a Bleomycin-Induced Pulmonary Fibrosis Murine Model, Front Vet Sci. 2020 Oct 8;7:588592. doi: 10.3389/fvets.2020.588592. eCollection 2020.

Movellan, J., Urban, P., Moles, E., de la Fuente, J. M., Sierra, T., Serrano, J. L., & Fernandez-Busquets, X. (2014)., Amphiphilic dendritic derivatives as nanocarriers for the targeted delivery of antimalarial drugs., Biomaterials, 35(27), 7940-7950. doi:10.1016/j.biomaterials.2014.05.061 [doi]

Novoa, E. M., Camacho, N., Tor, A., Wilkinson, B., Moss, S., Marin-Garcia, P., . . . Ribas de Pouplana, L. (2014)., Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo., Proceedings of the National Academy of Sciences of the United States of America, 111(51), E5508-17. doi:10.1073/pnas.1405994111 [doi]

Savignac, H. M., Kiely, B., Dinan, T. G., & Cryan, J. F. (2014)., Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice., Neurogastroenterology and Motility : The Official Journal of the European Gastrointestinal Motility Society, 26(11), 1615-1627. doi:10.1111/nmo.12427 [doi]

Savignac, H. M., Tramullas, M., Kiely, B., Dinan, T. G., & Cryan, J. F. (2015)., Bifidobacteria modulate cognitive processes in an anxious mouse strain, Behavioural Brain Research, 287, 59-72. doi:10.1016/j.bbr.2015.02.044 [doi]

Schnaider L, Toprakcioglu Z, Ezra A, Liu X, Bychenko D, Levin A, Gazit E, Knowles TPJ., Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo, Nano Lett. 2020 Mar 11;20(3):1590-1597. doi: 10.1021/acs.nanolett.9b04290. Epub 2020 Feb 17.

Felice, D., O'Leary, O. F., Pizzo, R. C., & Cryan, J. F. (2012)., Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action., Neuropharmacology, 63(8), 1380-1388. doi:10.1016/j.neuropharm.2012.06.066 [doi]

Roux, C. M., Rolan, H. G., Santos, R. L., Beremand, P. D., Thomas, T. L., Adams, L. G., & Tsolis, R. M. (2007), Brucella requires a functional type IV secretion system to elicit innate immune responses in mice., Cellular Microbiology, 9(7), 1851-1869. doi:CMI922 [pii]

Zogaj, X., Chakraborty, S., Liu, J., Thanassi, D. G., & Klose, K. E. (2008)., Characterization of the francisella tularensis subsp. novicida type IV pilus, Microbiology (Reading, England), 154(Pt 7), 2139-2150. doi:10.1099/mic.0.2008/018077-0 [doi]

Liu, Y., Muir, B. W., Waddington, L. J., Hinton, T. M., Moffat, B. A., Hao, X., . . . Hughes, T. C. (2015)., Colloidally stabilized magnetic carbon nanotubes providing MRI contrast in mouse liver tumors., Biomacromolecules, 16(3), 790-797. doi:10.1021/bm501706x [doi]

Oh, D. H., Lee, I. Y., Choi, M., Kim, S. H., & Son, H. (2012)., Comparison of neurite outgrowth induced by erythropoietin (EPO) and carbamylated erythropoietin (CEPO) in hippocampal neural progenitor cells., The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 16(4), 281-285. doi:10.4196/kjpp.2012.16.4.281 [doi]

Pérez P, Marín MQ, Lázaro-Frías A, Sorzano CÓS, Gómez CE, Esteban M, García-Arriaza J., Deletion of Vaccinia Virus A40R Gene Improves the Immunogenicity of the HIV-1 Vaccine Candidate MVA-B, Vaccines (Basel). 2020 Feb 6;8(1):70. doi: 10.3390/vaccines8010070.

van der Veen EL, Suurs FV, Cleeren F, Bormans G, Elsinga PH, Hospers GAP, Lub-de Hooge MN, de Vries EGE, de Vries EFJ, Antunes IF., Development and Evaluation of Interleukin-2-Derived Radiotracers for PET Imaging of T Cells in Mice, J Nucl Med. 2020 Sep;61(9):1355-1360. doi: 10.2967/jnumed.119.238782. Epub 2020 Feb 28.

Azcarate, I. G., Marin-Garcia, P., Perez-Benavente, S., Diez, A., Puyet, A., & Bautista, J. M. (2015), Early and late B cell immune responses in lethal and self-cured rodent malaria., Immunobiology, 220(5), 684-691. doi:10.1016/j.imbio.2014.11.010 [doi]

Bjorn, C., Noppa, L., Naslund Salomonsson, E., Johansson, A. L., Nilsson, E., Mahlapuu, M., & Hakansson, J. (2015)., Efficacy and safety profile of the novel antimicrobial peptide PXL150 in a mouse model of infected burn wounds., International Journal of Antimicrobial Agents, 45(5), 519-524. doi:10.1016/j.ijantimicag.2014.12.015 [doi]

Kamali, A. N., Marin-Garcia, P., Azcarate, I. G., Puyet, A., Diez, A., & Bautista, J. M. (2015)., Experimental immunization based on plasmodium antigens isolated by antibody affinity., Journal of Immunology Research, 2015, 723946. doi:10.1155/2015/723946 [doi]

Sweeney, F. F., O'Leary, O. F., & Cryan, J. F. (2013)., GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice., Behavioural Brain Research, 256, 151-156. doi:10.1016/j.bbr.2013.07.035 [doi]

Delviks-Frankenberry, K., Paprotka, T., Cingoz, O., Wildt, S., Hu, W. S., Coffin, J. M., & Pathak, V. K. (2013)., Generation of multiple replication-competent retroviruses through recombination between PreXMRV-1 and PreXMRV-2., Journal of Virology, 87(21), 11525-11537. doi:10.1128/JVI.01787-13 [doi]

Burket JA, Pickle JC, Rusk AM, Haynes BA, Sharp JA, Deutsch SI., Glycine transporter type 1 (GlyT1) inhibition improves conspecific-provoked immobility in BALB/c mice: Analysis of corticosterone response and glucocorticoid gene expression in cortex and hippocampus, Prog Neuropsychopharmacol Biol Psychiatry. 2020 Apr 20;99:109869. doi: 10.1016/j.pnpbp.2020.109869. Epub 2020 Jan 18.

O'Connor, R. M., Pusceddu, M. M., O'Leary, O. F., Savignac, H. M., Bravo, J. A., El Yacoubi, M., . . . Cryan, J. F. (2013)., Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action., Pharmacology, Biochemistry, and Behavior, 103(3), 561-567. doi:10.1016/j.pbb.2012.09.017 [doi]

Borges, O., Cordeiro-da-Silva, A., Tavares, J., Santarem, N., de Sousa, A., Borchard, G., & Junginger, H. E. (2008), Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles., European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 405-416. doi:10.1016/j.ejpb.2008.01.019 [doi]

Brickman, T. J., & Armstrong, S. K. (2007)., Impact of alcaligin siderophore utilization on in vivo growth of bordetella pertussis., Infection and Immunity, 75(11), 5305-5312. doi:IAI.00849-07 [pii]

Salomons, A. R., Arndt, S. S., & Ohl, F. (2012)., Impact of anxiety profiles on cognitive performance in BALB/c and 129P2 mice., Cognitive, Affective & Behavioral Neuroscience, 12(4), 794-803. doi:10.3758/s13415-012-0109-7 [doi]

Terwisscha van Scheltinga, A. G., Lub-de Hooge, M. N., Hinner, M. J., Verheijen, R. B., Allersdorfer, A., Hulsmeyer, M., . . . Olwill, S. A. (2014), In vivo visualization of MET tumor expression and anticalin biodistribution with the MET-specific anticalin 89Zr-PRS-110 PET tracer., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 55(4), 665-671. doi:10.2967/jnumed.113.124941 [doi]

Savignac, H. M., Finger, B. C., Pizzo, R. C., O'Leary, O. F., Dinan, T. G., & Cryan, J. F. (2011), Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain., Neuroscience, 192, 524-536. doi:10.1016/j.neuroscience.2011.04.054 [doi]

Gomez-Gallego, C., Collado, M. C., Ilo, T., Jaakkola, U. M., Bernal, M. J., Periago, M. J., . . . Frias, R. (2012)., Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice., The Journal of Nutritional Biochemistry, 23(11), 1508-1513. doi:10.1016/j.jnutbio.2011.10.003 [doi]

Cestari, I., & Stuart, K. (2013, Inhibition of isoleucyl-tRNA synthetase as a potential treatment for human african trypanosomiasis., The Journal of Biological Chemistry, 288(20), 14256-14263. doi:10.1074/jbc.M112.447441 [doi]

Azcarate, I. G., Marin-Garcia, P., Camacho, N., Perez-Benavente, S., Puyet, A., Diez, A., . . . Bautista, J. M. (2013)., Insights into the preclinical treatment of blood-stage malaria by the antibiotic borrelidin., British Journal of Pharmacology, 169(3), 645-658. doi:10.1111/bph.12156 [doi]

Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J., Iannelli, F., . . . Dockrell, D. H. (2012)., Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages, Infection and Immunity, 80(3), 1140-1149. doi:10.1128/IAI.05697-11 [doi]

Blockus S, Sake SM, Wetzke M, Grethe C, Graalmann T, Pils M, Le Goffic R, Galloux M, Prochnow H, Rox K, HĂźttel S, Rupcic Z, Wiegmann B, Dijkman R, Rameix-Welti MA, ElĂŠouĂŤt JF, Duprex WP, Thiel V, Hansen G, BrĂśnstrup M, Haid S, Pietschmann T., Labyrinthopeptins as virolytic inhibitors of respiratory syncytial virus cell entry, Antiviral Res. 2020 May;177:104774. doi: 10.1016/j.antiviral.2020.104774. Epub 2020 Mar 18.

Oude Munnink, T. H., de Vries, E. G., Vedelaar, S. R., Timmer-Bosscha, H., Schroder, C. P., Brouwers, A. H., & Lub-de Hooge, M. N. (2012)., Lapatinib and 17AAG reduce 89Zr-trastuzumab-F(ab')2 uptake in SKBR3 tumor xenografts., Molecular Pharmaceutics, 9(11), 2995-3002. doi:10.1021/mp3002182 [doi]

O'Leary, O. F., Zandy, S., Dinan, T. G., & Cryan, J. F. (2013)., Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: A role for hippocampal cell proliferation., Neuroscience, 228, 36-46. doi:10.1016/j.neuroscience.2012.09.072 [doi]

O'Leary, O. F., O'Connor, R. M., & Cryan, J. F. (2012), Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice., Neuropharmacology, 62(1), 247-255. doi:10.1016/j.neuropharm.2011.07.015 [doi]

van der Bilt, A. R., Terwisscha van Scheltinga, A. G., Timmer-Bosscha, H., Schroder, C. P., Pot, L., Kosterink, J. G., . . . Reyners, A. K. (2012)., Measurement of tumor VEGF-A levels with 89Zr-bevacizumab PET as an early biomarker for the antiangiogenic effect of everolimus treatment in an ovarian cancer xenograft model., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(22), 6306-6314. doi:10.1158/1078-0432.CCR-12-0406 [doi]

Gottfries, J., Melgar, S., & Michaelsson, E. (2012)., Modelling of mouse experimental colitis by global property screens: A holistic approach to assess drug effects in inflammatory bowel disease., PloS One, 7(1), e30005. doi:10.1371/journal.pone.0030005 [doi]

Bragonzi, A. (2010), Murine models of acute and chronic lung infection with cystic fibrosis pathogens, International Journal of Medical Microbiology : IJMM, 300(8), 584-593. doi:10.1016/j.ijmm.2010.08.012 [doi]

Muchnik, L., Adawi, A., Ohayon, A., Dotan, S., Malka, I., Azriel, S., . . . Nebenzahl, Y. M. (2013)., NADH oxidase functions as an adhesin in streptococcus pneumoniae and elicits a protective immune response in mice., PloS One, 8(4), e61128. doi:10.1371/journal.pone.0061128 [doi]

Halbroth BR, Sebastian S, Salman AM, Ulaszewska M, Gola A, Longley RJ, Janse CJ, Khan SM, Hill AVS, Spencer AJ., Preclinical Development and Assessment of Viral Vectors Expressing a Fusion Antigen of Plasmodium falciparum LSA1 and LSAP2 for Efficacy against Liver-Stage Malaria, Infect Immun. 2020 Jan 22;88(2):e00573-19. doi: 10.1128/IAI.00573-19. Print 2020 Jan 22.

Flores-Villasenor, H., Canizalez-Roman, A., Velazquez-Roman, J., Nazmi, K., Bolscher, J. G., & Leon-Sicairos, N. (2012)., Protective effects of lactoferrin chimera and bovine lactoferrin in a mouse model of enterohaemorrhagic escherichia coli O157:H7 infection., Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 90(3), 405-411. doi:10.1139/o11-089 [doi]

Gomez-Gallego, C., Collado, M. C., Perez, G., Ilo, T., Jaakkola, U. M., Bernal, M. J., . . . Salminen, S. (2014)., Resembling breast milk: Influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota., The British Journal of Nutrition, 111(6), 1050-1058. doi:10.1017/S0007114513003565 [doi]

Savignac, H. M., Dinan, T. G., & Cryan, J. F. (2011)., Resistance to early-life stress in mice: Effects of genetic background and stress duration., Frontiers in Behavioral Neuroscience, 5, 13. doi:10.3389/fnbeh.2011.00013 [doi]

England RM, Moss JI, Gunnarsson A, Parker JS, Ashford MB., Synthesis and Characterization of Dendrimer-Based Polysarcosine Star Polymers: Well-Defined, Versatile Platforms Designed for Drug-Delivery Applications, Biomacromolecules. 2020 Aug 10;21(8):3332-3341. doi: 10.1021/acs.biomac.0c00768. Epub 2020 Jul 28.

Morales, P., Vara, D., Gomez-Canas, M., Zuniga, M. C., Olea-Azar, C., Goya, P., . . . Jagerovic, N. (2013)., Synthetic cannabinoid quinones: Preparation, in vitro antiproliferative effects and in vivo prostate antitumor activity., European Journal of Medicinal Chemistry, 70, 111-119. doi:10.1016/j.ejmech.2013.09.043 [doi]

Gonzalez, R., Ferrin, G., Aguilar-Melero, P., Ranchal, I., Linares, C. I., Bello, R. I., . . . Muntane, J. (2013)., Targeting hepatoma using nitric oxide donor strategies., Antioxidants & Redox Signaling, 18(5), 491-506. doi:10.1089/ars.2011.4476 [doi]

Suurs FV, Lorenczewski G, Stienen S, Friedrich M, de Vries EGE, de Groot DJA, Lub-de Hooge MN., The Biodistribution of a CD3 and EpCAM Bispecific T-Cell Engager Is Driven by the CD3 Arm, J Nucl Med. 2020 Nov;61(11):1594-1601. doi: 10.2967/jnumed.120.241877. Epub 2020 Apr 13.

Aranda, J., Garrido, M. E., Fittipaldi, N., Cortes, P., Llagostera, M., Gottschalk, M., & Barbe, J. (2010)., The cation-uptake regulators AdcR and fur are necessary for full virulence of streptococcus suis., Veterinary Microbiology, 144(1-2), 246-249. doi:10.1016/j.vetmic.2009.12.037 [doi]

Huuskonen, M. T., Tuo, Q. Z., Loppi, S., Dhungana, H., Korhonen, P., McInnes, L. E., . . . Kanninen, K. M. (2017)., The copper bis(thiosemicarbazone) complex cu(II)(atsm) is protective against cerebral ischemia through modulation of the inflammatory milieu., Neurotherapeutics : The Journal of the American Society for Experimental NeuroTherapeutics, 14(2), 519-532. doi:10.1007/s13311-016-0504-9 [doi]

Savignac, H. M., Hyland, N. P., Dinan, T. G., & Cryan, J. F. (2011), The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain., Behavioural Brain Research, 216(2), 576-584. doi:10.1016/j.bbr.2010.08.049 [doi]

Barradas, A. M., Yuan, H., van der Stok, J., Le Quang, B., Fernandes, H., Chaterjea, A., . . . de Boer, J. (2012)., The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice., Biomaterials, 33(23), 5696-5705. doi:10.1016/j.biomaterials.2012.04.021 [doi]

Roper, J., O'Carroll, A. M., Young, W.,3rd, & Lolait, S. (2011)., The vasopressin Avpr1b receptor: Molecular and pharmacological studies, Stress (Amsterdam, Netherlands), 14(1), 98-115. doi:10.3109/10253890.2010.512376 [doi]

Makdasi E, Amsili S, Aronin A, Prigozhina TB, Tzdaka K, Gozlan YM, Ben Gigi-Tamir L, Sagiv JY, Shkedy F, Shani N, Tykocinski ML, Dranitzki Elhalel M., Toxicology and Pharmacokinetic Studies in Mice and Nonhuman Primates of the Nontoxic, Efficient, Targeted Hexameric FasL: CTLA4-FasL, Mol Cancer Ther. 2020 Feb;19(2):513-524. doi: 10.1158/1535-7163.MCT-19-0558. Epub 2019 Dec 23.

Urban, P., Valle-Delgado, J. J., Mauro, N., Marques, J., Manfredi, A., Rottmann, M., . . . Fernandez-Busquets, X. (2014)., Use of poly(amidoamine) drug conjugates for the delivery of antimalarials to plasmodium, Journal of Controlled Release : Official Journal of the Controlled Release Society, 177, 84-95. doi:10.1016/j.jconrel.2013.12.032 [doi]

Terwisscha van Scheltinga, A. G., Berghuis, P., Nienhuis, H. H., Timmer-Bosscha, H., Pot, L., Gaykema, S. B., . . . Schroder, C. P. (2014)., Visualising dual downregulation of insulin-like growth factor receptor-1 and vascular endothelial growth factor-A by heat shock protein 90 inhibition effect in triple negative breast cancer., European Journal of Cancer (Oxford, England : 1990), 50(14), 2508-2516. doi:10.1016/j.ejca.2014.06.008 [doi]

Liu, Y., Hughes, T. C., Muir, B. W., Waddington, L. J., Gengenbach, T. R., Easton, C. D., . . . Qiu, J. (2014)., Water-dispersible magnetic carbon nanotubes as T2-weighted MRI contrast agents, Biomaterials, 35(1), 378-386. doi:10.1016/j.biomaterials.2013.09.079 [doi]

Gómez-Aguado I, et al., mRNA-Based Nanomedicinal Products to Address Corneal Inflammation by Interleukin-10 Supplementation., Pharmaceutics. 2021 Sep 15;13(9). pii: 1472. doi: 10.3390/pharmaceutics13091472.

Westlund KN, Montera MA, Goins AE, Alles SRA, Afaghpour-Becklund M, Bartel R, Durvasula R, Kunamneni A., Single-chain Fragment variable antibody targeting cholecystokinin-B receptor for pain reduction., Neurobiol Pain. 2021 Jul 15;10:100067. doi: 10.1016/j.ynpai.2021.100067. eCollection 2021 Aug-Dec.

Lugo-Fabres PH, Otero-Sastre LM, Bernáldez-Sarabia J, Camacho-Villegas TA, Sánchez-Campos N, Serrano-Bello J, Medina LA, Muñiz-Hernández S, de la Cruz L, Arenas I, Barajas-Martínez A, Garcia DE, Nuñez-Garcia L, González-Canudas J, Licea-Navarro AF., Potential Therapeutic Applications of Synthetic Conotoxin s-cal14.2b, Derived from Californiconus californicus, for Treating Type 2 Diabetes., Biomedicines. 2021 Aug 1;9(8). pii: 936. doi: 10.3390/biomedicines9080936.

Gautam N, McMillan JM, Kumar D, Bade AN, Pan Q, Kulkarni TA, Li W, Sillman B, Smith NA, Shetty BLD, Szlachetka A, Edagwa BJ, Gendelman HE, Alnouti Y., Lipophilic nanocrystal prodrug-release defines the extended pharmacokinetic profiles of a year-long cabotegravir., Nat Commun. 2021 Jun 8;12(1):3453. doi: 10.1038/s41467-021-23668-x.

van Ballegooie C, Wretham N, Ren T, Popescu IM, Yapp DT, Bally MB., PEG Conjugated Zein Nanoparticles for In Vivo Use, Pharmaceutics. 2022 Aug 31;14(9):1831. doi: 10.3390/pharmaceutics14091831.

Chang PY, Bakke J, Rosen CJ, Bjornstad KA, Mao JH, Blakely EA., Heavy-Ion-Induced Lung Tumors: Dose- & LET-Dependence, Life (Basel). 2022 Jun 17;12(6):907. doi: 10.3390/life12060907.

Estrada S, Elgland M, Selvaraju RK, Mani K, Tegler G, Wanhainen A, Wågsäter D, Bergström M, Jimenez-Royo P, Jahan M, Nordeman P, Antoni G., Preclinical evaluation of [(11)C]GW457427 as a tracer for neutrophil elastase, Nucl Med Biol. 2022 Mar-Apr;106-107:62-71. doi: 10.1016/j.nucmedbio.2022.01.001. Epub 2022 Jan 11.

Yang Z, Rajendran S, Spires V, Poirson B, Gururajan M, Lin Z, Arbanas J, Krystek S, Loy J, Cheng Y, Carl S, Pace S, Wang Y, Mehl J, Xu S, Vasudevan K, Broz M, Lehman-McKeeman L, Morin P, Graziano RF., Target-Mediated Drug Disposition Affects the Pharmacokinetics of Interleukin-10 Fragment Crystallizable Fusion Proteins at Pharmacologically Active Doses, Drug Metab Dispos. 2022 Jul;50(7):898-908. doi: 10.1124/dmd.121.000799

Marin AA, Decker RE, Kumar S, Lamantia Z, Yokota H, Emrick T, Figueiredo ML., Enhancing Prednisone-Based Arthritis Therapy with Targeted IL-27 Gene Delivery, Gene Delivery. Bioengineering (Basel). 2022 Jun 9;9(6):248.

Meyer RA, Hussmann GP, Peterson NC, Santos JL, Tuesca AD., A scalable and robust cationic lipid/polymer hybrid nanoparticle platform for mRNA delivery, Int J Pharm. 2022 Jan 5;611:121314. doi: 10.1016/j.ijpharm.2021.121314

Xu Y, Harinck L, Lokras AG, Gerde P, Selg E, Sjöberg CO, Franzyk H, Thakur A, Foged C., Leucine improves the aerosol performance of dry powder inhaler formulations of siRNA-loaded nanoparticles, Int J Pharm. 2022 Jun 10;621:121758. doi: 10.1016/j.ijpharm.2022.121758. Epub 2022 Apr 26.

Teratology

Craig, M., & Slauch, J. M. (2009), Phagocytic superoxide specifically damages an extracytoplasmic target to inhibit or kill salmonella., PloS One, 4(3), e4975. doi:10.1371/journal.pone.0004975 [doi]

Montalban-Soler, L., Alarcon-Martinez, L., Jimenez-Lopez, M., Salinas-Navarro, M., Galindo-Romero, C., Bezerra de Sa, F., . . . Villegas-Perez, M. P. (2012)., Retinal compensatory changes after light damage in albino mice., Molecular Vision, 18, 675-693.

Kawedia, J. D., Janke, L., Funk, A. J., Ramsey, L. B., Liu, C., Jenkins, D., . . . Relling, M. V. (2012)., Substrain-specific differences in survival and osteonecrosis incidence in a mouse model., Comparative Medicine, 62(6), 466-471.

Williams, L. K., Csaki, L. S., Cantor, R. M., Reue, K., & Lawson, G. W. (2012)., Ulcerative dermatitis in C57BL/6 mice exhibits an oxidative stress response consistent with normal wound healing, Comparative Medicine, 62(3), 166-171.

Toxicology

Kienhuis, A. S., Slob, W., Gremmer, E. R., Vermeulen, J. P., & Ezendam, J. (2015)., A dose-response modeling approach shows that effects from mixture exposure to the skin sensitizers isoeugenol and cinnamal are in line with dose addition and not with synergism, Toxicological Sciences : An Official Journal of the Society of Toxicology, 147(1), 68-74. doi:10.1093/toxsci/kfv109 [doi]

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